Published in J Virol on March 28, 2007
Cellular reservoirs of HIV-1 and their role in viral persistence. Curr HIV Res (2008) 2.40
HIV-1 transcription and latency: an update. Retrovirology (2013) 1.49
Active beta-catenin signaling is an inhibitory pathway for human immunodeficiency virus replication in peripheral blood mononuclear cells. J Virol (2008) 1.18
IFN-gamma mediates enhancement of HIV replication in astrocytes by inducing an antagonist of the beta-catenin pathway (DKK1) in a STAT 3-dependent manner. J Immunol (2011) 1.18
Targeting Wnt pathways in disease. Cold Spring Harb Perspect Biol (2012) 1.11
Role of β-catenin and TCF/LEF family members in transcriptional activity of HIV in astrocytes. J Virol (2011) 1.09
RNA Viruses: ROS-Mediated Cell Death. Int J Cell Biol (2014) 1.01
HIV-1 gp120 and drugs of abuse: interactions in the central nervous system. Curr HIV Res (2012) 0.98
HIV gp120- and methamphetamine-mediated oxidative stress induces astrocyte apoptosis via cytochrome P450 2E1. Cell Death Dis (2013) 0.96
Cocaine and HIV-1 interplay: molecular mechanisms of action and addiction. J Neuroimmune Pharmacol (2011) 0.93
Role of β-catenin/TCF-4 signaling in HIV replication and pathogenesis: insights to informing novel anti-HIV molecular therapeutics. J Neuroimmune Pharmacol (2011) 0.92
Interplay between Wnt/β-catenin signaling and HIV: virologic and biologic consequences in the CNS. J Neuroimmune Pharmacol (2012) 0.89
Identification of novel T cell factor 4 (TCF-4) binding sites on the HIV long terminal repeat which associate with TCF-4, β-catenin, and SMAR1 to repress HIV transcription. J Virol (2012) 0.89
Epigenetic regulation of HIV-1 latency in astrocytes. J Virol (2013) 0.89
Inhibition of Tat-mediated HIV-1 replication and neurotoxicity by novel GSK3-beta inhibitors. Virology (2011) 0.88
Mechanisms of HIV Transcriptional Regulation and Their Contribution to Latency. Mol Biol Int (2012) 0.86
Methamphetamine and HIV-1 Tat down regulate β-catenin signaling: implications for methampetamine abuse and HIV-1 co-morbidity. J Neuroimmune Pharmacol (2011) 0.85
Mitogen-activated protein kinase p38 in HIV infection and associated brain injury. J Neuroimmune Pharmacol (2011) 0.83
Dynamic interaction between astrocytes and infiltrating PBMCs in context of neuroAIDS. Glia (2014) 0.81
Interactions of HIV and drugs of abuse: the importance of glia, neural progenitors, and host genetic factors. Int Rev Neurobiol (2014) 0.81
Cell-cell contact viral transfer contributes to HIV infection and persistence in astrocytes. J Neurovirol (2014) 0.80
Limited TCF7L2 expression in MS lesions. PLoS One (2013) 0.80
HIV-1, methamphetamine and astrocytes at neuroinflammatory Crossroads. Front Microbiol (2015) 0.80
HIV eradication: combinatorial approaches to activate latent viruses. Viruses (2014) 0.77
Opiate addiction therapies and HIV-1 Tat: interactive effects on glial [Ca²⁺]i, oxyradical and neuroinflammatory chemokine production and correlative neurotoxicity. Curr HIV Res (2014) 0.76
HIV's Nef interacts with β-catenin of the Wnt signaling pathway in HEK293 cells. PLoS One (2013) 0.76
HIV-tat alters Connexin43 expression and trafficking in human astrocytes: role in NeuroAIDS. J Neuroinflammation (2016) 0.76
Mechanisms of HIV Neuropathogenesis: Role of Cellular Communication Systems. Curr HIV Res (2016) 0.75
Macrophages and Phospholipases at the Intersection between Inflammation and the Pathogenesis of HIV-1 Infection. Int J Mol Sci (2017) 0.75
Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients. Proc Natl Acad Sci U S A (1986) 8.45
Wnt signalling regulates adult hippocampal neurogenesis. Nature (2005) 6.66
Human immunodeficiency virus can productively infect cultured human glial cells. Proc Natl Acad Sci U S A (1987) 3.14
TCF transcription factors: molecular switches in carcinogenesis. Biochim Biophys Acta (1999) 2.37
HTLV-III/LAV-like retrovirus particles in the brains of patients with AIDS encephalopathy. AIDS Res (1986) 2.27
Human immunodeficiency virus (HIV) proteins in neuropathogenesis of HIV dementia. J Infect Dis (2002) 2.19
Detection of HIV-1 DNA in microglia/macrophages, astrocytes and neurons isolated from brain tissue with HIV-1 encephalitis by laser capture microdissection. Brain Pathol (2003) 2.11
Differential activation of astrocytes by innate and adaptive immune stimuli. Glia (2005) 1.99
Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription. Eur J Immunol (2001) 1.63
Partial rescue of the Vif-negative phenotype of mutant human immunodeficiency virus type 1 strains from nonpermissive cells by intravirion reverse transcription. J Virol (2000) 1.60
Histone deacetylase inhibitors: multifunctional anticancer agents. Cancer Treat Rev (2006) 1.57
HIV-1 TAR RNA: the target of molecular interactions between the virus and its host. Curr HIV Res (2005) 1.56
Ultrastructural morphology and intracellular production of human immunodeficiency virus (HIV) in brain. J Neuropathol Exp Neurol (1987) 1.54
CD4-independent infection of astrocytes by human immunodeficiency virus type 1: requirement for the human mannose receptor. J Virol (2004) 1.52
Temporal patterns of human immunodeficiency virus type 1 transcripts in human fetal astrocytes. J Virol (1994) 1.50
Astrocyte infection by HIV-1: mechanisms of restricted virus replication, and role in the pathogenesis of HIV-1-associated dementia. Curr HIV Res (2003) 1.47
The TAR RNA-binding protein, TRBP, stimulates the expression of TAR-containing RNAs in vitro and in vivo independently of its ability to inhibit the dsRNA-dependent kinase PKR. J Biol Chem (2002) 1.47
Two dimerization domains in the trans-activation response RNA-binding protein (TRBP) individually reverse the protein kinase R inhibition of HIV-1 long terminal repeat expression. J Biol Chem (2001) 1.42
Effects of human immunodeficiency virus type 1 on astrocyte gene expression and function: potential role in neuropathogenesis. J Neurovirol (2004) 1.38
Stabilized beta-catenin extends thymocyte survival by up-regulating Bcl-xL. J Immunol (2005) 1.37
HIV-1 down-regulates the expression of CD1d via Nef. Eur J Immunol (2006) 1.36
Repressor roles for TCF-4 and Sfrp1 in Wnt signaling in breast cancer. Oncogene (2006) 1.35
Astrocytes protect neurons from nitric oxide toxicity by a glutathione-dependent mechanism. J Neurochem (2001) 1.35
Gene expression array of HTLV type 1-infected T cells: Up-regulation of transcription factors and cell cycle genes. AIDS Res Hum Retroviruses (2000) 1.30
Deciphering the roles of the histone H2B N-terminal domain in genome-wide transcription. Mol Cell Biol (2006) 1.28
Environmental signals and cell fate specification in premigratory neural crest. Bioessays (2000) 1.28
Highly productive infection with pseudotyped human immunodeficiency virus type 1 (HIV-1) indicates no intracellular restrictions to HIV-1 replication in primary human astrocytes. J Virol (2001) 1.28
SWI/SNF remodeling and p300-dependent transcription of histone variant H2ABbd nucleosomal arrays. EMBO J (2004) 1.23
Restriction of human immunodeficiency virus type 1 production in a human astrocytoma cell line is associated with a cellular block in Rev function. J Virol (1995) 1.23
Histone deacetylase inhibitors: latest developments, trends and prospects. Curr Med Chem Anticancer Agents (2005) 1.19
Cyr61 suppresses the growth of non-small-cell lung cancer cells via the beta-catenin-c-myc-p53 pathway. Oncogene (2004) 1.19
Impaired cell surface expression of human CD1d by the formation of an HIV-1 Nef/CD1d complex. Virology (2005) 1.19
Low TRBP levels support an innate human immunodeficiency virus type 1 resistance in astrocytes by enhancing the PKR antiviral response. J Virol (2005) 1.17
Detection and localisation of HIV-1 DNA and RNA in fixed adult AIDS brain by polymerase chain reaction/in situ hybridisation technique. Acta Neuropathol (1999) 1.14
Astrocytes prevent neuronal death induced by reactive oxygen and nitrogen species. Glia (1999) 1.14
HIV type 1 infection of human astrocytes is restricted by inefficient viral entry. AIDS Res Hum Retroviruses (2001) 1.09
Nonproductive human immunodeficiency virus type 1 infection of human fetal astrocytes: independence from CD4 and major chemokine receptors. Virology (1999) 1.09
Gamma interferon primes productive human immunodeficiency virus infection in astrocytes. J Virol (2006) 1.07
Diminished rev-mediated stimulation of human immunodeficiency virus type 1 protein synthesis is a hallmark of human astrocytes. J Virol (1999) 1.06
Expression of exogenous Sam68, the 68-kilodalton SRC-associated protein in mitosis, is able to alleviate impaired Rev function in astrocytes. J Virol (2002) 1.05
Direct participation of Sam68, the 68-kilodalton Src-associated protein in mitosis, in the CRM1-mediated Rev nuclear export pathway. J Virol (2002) 1.04
Gene expression changes and signaling events associated with the direct antimelanoma effect of IFN-gamma. Cancer Res (2005) 1.03
Crosstalk between components of the blood brain barrier and cells of the CNS in microglial activation in AIDS. Brain Pathol (2001) 1.02
Astrocyte activation and apoptosis: their roles in the neuropathology of HIV infection. Brain Pathol (2003) 1.01
Novel pathway of human immunodeficiency virus type 1 uptake and release in astrocytes. Virology (2006) 0.99
Regulation of HIV-1 infection in astrocytes: expression of Nef, TNF-alpha and IL-6 is enhanced in coculture of astrocytes with macrophages. J Neurovirol (1996) 0.97
Role for human immunodeficiency virus type 1 Tat protein in suppression of viral reverse transcriptase activity during late stages of viral replication. J Virol (2001) 0.95
Human immunodeficiency virus type 1 Tat prevents dephosphorylation of Sp1 by TCF-4 in astrocytes. J Gen Virol (2006) 0.94
Evidence for regulation of long terminal repeat transcription by Wnt transcription factor TCF-4 in human astrocytic cells. J Virol (2002) 0.94
Replication of different clones of human immunodeficiency virus type 1 in primary fetal human astrocytes: enhancement of viral gene expression by Nef. J Neurovirol (1999) 0.93
Wnt signaling in lymphopoiesis. Curr Top Microbiol Immunol (2005) 0.92
Differential abilities of central nervous system resident endothelial cells and astrocytes to serve as inducible antigen-presenting cells. Blood (2002) 0.91
Detection of human immunodeficiency virus type 1 infection in young pediatric patients by using polymerase chain reaction and biotinylated probes. J Clin Microbiol (1992) 0.90
Stimulation of HIV type 1 gene expression and induction of NF-kappa B (p50/p65)-binding activity in tumor necrosis factor alpha-treated human fetal glial cells. AIDS Res Hum Retroviruses (1994) 0.84
A mechanism of restricted human immunodeficiency virus type 1 expression in human glial cells. J Virol (1996) 0.82
Chromatin modifications (acetylation/ deacetylation/ methylation) as new targets for HIV therapy. Curr Pharm Des (2006) 0.81
Immune modulation of HIV replication: relevance to HIV immuno- and neuro-pathogenesis. Curr HIV Res (2004) 0.77
HIV-1 TAR element is processed by Dicer to yield a viral micro-RNA involved in chromatin remodeling of the viral LTR. BMC Mol Biol (2007) 2.20
Interleukin-7-treated naive T cells can be productively infected by T-cell-adapted and primary isolates of human immunodeficiency virus 1. Blood (2002) 1.70
Differential requirement of PKC-theta in the development and function of natural regulatory T cells. Mol Immunol (2008) 1.63
Tat gets the "green" light on transcription initiation. Retrovirology (2005) 1.61
CD8(+) T cell activation in women coinfected with human immunodeficiency virus type 1 and hepatitis C virus. J Infect Dis (2008) 1.49
Anti-HTLV antibody profiling reveals an antibody signature for HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Retrovirology (2008) 1.45
Long-term mitochondrial toxicity in HIV-uninfected infants born to HIV-infected mothers. J Acquir Immune Defic Syndr (2003) 1.44
Activation of CD8 T cells predicts progression of HIV infection in women coinfected with hepatitis C virus. J Infect Dis (2010) 1.42
Whole-blood interleukin-18 level during early HIV-1 infection is associated with reduced CXCR4 coreceptor expression and interferon- gamma levels. J Infect Dis (2007) 1.42
Enhancement of nuclear factor-kappa B acetylation by coactivator p300 and HIV-1 Tat proteins. J Biol Chem (2001) 1.42
The utilization of humanized mouse models for the study of human retroviral infections. Retrovirology (2009) 1.42
Intracytoplasmic maturation of the human immunodeficiency virus type 1 reverse transcription complexes determines their capacity to integrate into chromatin. Retrovirology (2006) 1.39
Effect of SWI/SNF chromatin remodeling complex on HIV-1 Tat activated transcription. Retrovirology (2006) 1.36
HIV-1 TAR miRNA protects against apoptosis by altering cellular gene expression. Retrovirology (2009) 1.35
Exosomes derived from HIV-1-infected cells contain trans-activation response element RNA. J Biol Chem (2013) 1.31
Coordination of transcription factor phosphorylation and histone methylation by the P-TEFb kinase during human immunodeficiency virus type 1 transcription. J Virol (2004) 1.30
Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR. Retrovirology (2008) 1.30
Protein profile of tax-associated complexes. J Biol Chem (2003) 1.28
Phosphorylation of HIV-1 Tat by CDK2 in HIV-1 transcription. Retrovirology (2006) 1.25
Gene expression profile of HIV-1 Tat expressing cells: a close interplay between proliferative and differentiation signals. BMC Biochem (2002) 1.24
Iron chelators of the di-2-pyridylketone thiosemicarbazone and 2-benzoylpyridine thiosemicarbazone series inhibit HIV-1 transcription: identification of novel cellular targets--iron, cyclin-dependent kinase (CDK) 2, and CDK9. Mol Pharmacol (2010) 1.21
Wnt/β-catenin and its diverse physiological cell signaling pathways in neurodegenerative and neuropsychiatric disorders. J Neuroimmune Pharmacol (2012) 1.19
Active beta-catenin signaling is an inhibitory pathway for human immunodeficiency virus replication in peripheral blood mononuclear cells. J Virol (2008) 1.18
Activation of plasmacytoid dendritic cells with TLR9 agonists initiates invariant NKT cell-mediated cross-talk with myeloid dendritic cells. J Immunol (2006) 1.18
Bromodomain protein Brd4 regulates human immunodeficiency virus transcription through phosphorylation of CDK9 at threonine 29. J Virol (2008) 1.18
The HTLV-I Tax oncoprotein targets the retinoblastoma protein for proteasomal degradation. Oncogene (2005) 1.18
Induction of DNA damage signaling upon Rift Valley fever virus infection results in cell cycle arrest and increased viral replication. J Biol Chem (2012) 1.18
IFN-gamma mediates enhancement of HIV replication in astrocytes by inducing an antagonist of the beta-catenin pathway (DKK1) in a STAT 3-dependent manner. J Immunol (2011) 1.18
Antiviral activity of CYC202 in HIV-1-infected cells. J Biol Chem (2004) 1.17
Negative-strand hepatitis C virus (HCV) RNA in peripheral blood mononuclear cells from anti-HCV-positive/HIV-infected women. J Infect Dis (2006) 1.17
HTLV tax: a fascinating multifunctional co-regulator of viral and cellular pathways. Front Microbiol (2012) 1.16
Absence of DICER in monocytes and its regulation by HIV-1. J Biol Chem (2010) 1.15
HIV-1 Tat interaction with RNA polymerase II C-terminal domain (CTD) and a dynamic association with CDK2 induce CTD phosphorylation and transcription from HIV-1 promoter. J Biol Chem (2002) 1.15
The Tat/TAR-dependent phosphorylation of RNA polymerase II C-terminal domain stimulates cotranscriptional capping of HIV-1 mRNA. Proc Natl Acad Sci U S A (2003) 1.13
Chromatin remodeling and modification during HIV-1 Tat-activated transcription. Curr HIV Res (2003) 1.12
Stimulation of the liver X receptor pathway inhibits HIV-1 replication via induction of ATP-binding cassette transporter A1. Mol Pharmacol (2010) 1.12
Nuclear targeting of protein phosphatase-1 by HIV-1 Tat protein. J Biol Chem (2005) 1.10
Role of β-catenin and TCF/LEF family members in transcriptional activity of HIV in astrocytes. J Virol (2011) 1.09
Gamma interferon primes productive human immunodeficiency virus infection in astrocytes. J Virol (2006) 1.07
Effect of transcription peptide inhibitors on HIV-1 replication. Virology (2008) 1.06
Acetylated Tat regulates human immunodeficiency virus type 1 splicing through its interaction with the splicing regulator p32. J Virol (2006) 1.06
p53 Activation following Rift Valley fever virus infection contributes to cell death and viral production. PLoS One (2012) 1.03
The role of cyclin D2 and p21/waf1 in human T-cell leukemia virus type 1 infected cells. Retrovirology (2004) 1.02
Chromatin dynamics associated with HIV-1 Tat-activated transcription. Biochim Biophys Acta (2009) 1.01
CD1d-restricted natural killer T cells are potent targets for human immunodeficiency virus infection. Immunology (2003) 1.01
Hepcidin induces HIV-1 transcription inhibited by ferroportin. Retrovirology (2010) 1.00
RNA interference directed to CDK2 inhibits HIV-1 transcription. Virology (2005) 0.99
CDK13, a new potential human immunodeficiency virus type 1 inhibitory factor regulating viral mRNA splicing. J Virol (2008) 0.99
Reverse-phase phosphoproteome analysis of signaling pathways induced by Rift valley fever virus in human small airway epithelial cells. PLoS One (2010) 0.98
Impact of class A, B and C CpG-oligodeoxynucleotides on in vitro activation of innate immune cells in human immunodeficiency virus-1 infected individuals. Immunology (2007) 0.98
Role of viral regulatory and accessory proteins in HIV-1 replication. Front Biosci (2004) 0.98
CDK2 regulates HIV-1 transcription by phosphorylation of CDK9 on serine 90. Retrovirology (2012) 0.95
Modulation of GSK-3β activity in Venezuelan equine encephalitis virus infection. PLoS One (2012) 0.95
The carrying pigeons of the cell: exosomes and their role in infectious diseases caused by human pathogens. Pathog Dis (2014) 0.95
Novel HIV-1 therapeutics through targeting altered host cell pathways. Expert Opin Biol Ther (2009) 0.94
Methylation of the tumor suppressor protein, BRCA1, influences its transcriptional cofactor function. PLoS One (2010) 0.94
Beta-catenin signaling mediates CD4 expression on mature CD8+ T cells. J Immunol (2010) 0.93
Activation of cyclin D1 and D2 promoters by human T-cell leukemia virus type I tax protein is associated with IL-2-independent growth of T cells. Int J Cancer (2002) 0.93
Potent HIV-specific responses are enriched in a unique subset of CD8+ T cells that coexpresses CD4 on its surface. Blood (2009) 0.93
Transcription through the HIV-1 nucleosomes: effects of the PBAF complex in Tat activated transcription. Virology (2010) 0.93
Identifying the membrane proteome of HIV-1 latently infected cells. J Biol Chem (2007) 0.92
Inhibition of HIV-1 virus replication using small soluble Tat peptides. Virology (2005) 0.92
Varying modulation of HIV-1 LTR activity by Baf complexes. J Mol Biol (2011) 0.92
Role of β-catenin/TCF-4 signaling in HIV replication and pathogenesis: insights to informing novel anti-HIV molecular therapeutics. J Neuroimmune Pharmacol (2011) 0.92
Potential use of pharmacological cyclin-dependent kinase inhibitors as anti-HIV therapeutics. Curr Pharm Des (2006) 0.92
Liver X receptor agonist inhibits HIV-1 replication and prevents HIV-induced reduction of plasma HDL in humanized mouse model of HIV infection. Biochem Biophys Res Commun (2012) 0.91
Analysis of the roles of HIV-derived microRNAs. Expert Opin Biol Ther (2011) 0.91
17β-Estradiol inhibits HIV-1 by inducing a complex formation between β-catenin and estrogen receptor α on the HIV promoter to suppress HIV transcription. Virology (2013) 0.89
Mechanisms of HTLV-1 transformation. Front Biosci (2004) 0.89
Identification of novel T cell factor 4 (TCF-4) binding sites on the HIV long terminal repeat which associate with TCF-4, β-catenin, and SMAR1 to repress HIV transcription. J Virol (2012) 0.89
NKG2D signaling on CD8⁺ T cells represses T-bet and rescues CD4-unhelped CD8⁺ T cell memory recall but not effector responses. Nat Med (2012) 0.89
Curcumin inhibits Rift Valley fever virus replication in human cells. J Biol Chem (2012) 0.89
Alteration in superoxide dismutase 1 causes oxidative stress and p38 MAPK activation following RVFV infection. PLoS One (2011) 0.89
Human T-lymphotropic virus type 1 transcription and chromatin-remodeling complexes. J Virol (2010) 0.89
Epigenetic regulation of HIV-1 latency in astrocytes. J Virol (2013) 0.89
Effect of mimetic CDK9 inhibitors on HIV-1-activated transcription. J Mol Biol (2012) 0.89
Dynamics of cytokine expression in HIV productively infected primary CD4+ T cells. Blood (2004) 0.88
Construction and characterization of a human T-cell lymphotropic virus type 3 infectious molecular clone. J Virol (2008) 0.88
Pharmacological cyclin-dependent kinase inhibitors as HIV-1 antiviral therapeutics. Curr HIV Res (2003) 0.88
Inhibition of Tat-mediated HIV-1 replication and neurotoxicity by novel GSK3-beta inhibitors. Virology (2011) 0.88
Inhibition of HTLV-1 transcription by cyclin dependent kinase inhibitors. Mol Cell Biochem (2002) 0.88
Bacillus anthracis interacts with plasmin(ogen) to evade C3b-dependent innate immunity. PLoS One (2011) 0.88
Therapeutic targets for HIV-1 infection in the host proteome. Retrovirology (2005) 0.88
Secreted Bacillus anthracis proteases target the host fibrinolytic system. FEMS Immunol Med Microbiol (2011) 0.87
Multiple populations of T lymphocytes are distinguished by the level of CD4 and CD8 coexpression and require individual consideration. J Leukoc Biol (2006) 0.87
Interleukin-7 induces HIV replication in primary naive T cells through a nuclear factor of activated T cell (NFAT)-dependent pathway. Virology (2006) 0.87
Use of a multi-virus array for the study of human viral and retroviral pathogens: gene expression studies and ChIP-chip analysis. Retrovirology (2004) 0.87
Drug 9AA reactivates p21/Waf1 and Inhibits HIV-1 progeny formation. Virol J (2008) 0.87
Enduring cortical alterations after a single in-vivo treatment of HIV-1 Tat. Neuroreport (2012) 0.87
XBP-1, a novel human T-lymphotropic virus type 1 (HTLV-1) tax binding protein, activates HTLV-1 basal and tax-activated transcription. J Virol (2008) 0.86
In vivo murine and in vitro M-like cell models of gastrointestinal anthrax. Microbes Infect (2012) 0.86
Interleukin-7 signalling is sufficient to phenotypically and functionally prime human CD4 naive T cells. Immunology (2005) 0.86
Paradoxical effects of a stress signal on pro- and anti-apoptotic machinery in HTLV-1 Tax expressing cells. Mol Cell Biochem (2003) 0.85
microRNA machinery is an integral component of drug-induced transcription inhibition in HIV-1 infection. J RNAi Gene Silencing (2010) 0.85