Published in J Virol on April 01, 1995
Cellular reservoirs of HIV-1 and their role in viral persistence. Curr HIV Res (2008) 2.40
Highly productive infection with pseudotyped human immunodeficiency virus type 1 (HIV-1) indicates no intracellular restrictions to HIV-1 replication in primary human astrocytes. J Virol (2001) 1.28
Low TRBP levels support an innate human immunodeficiency virus type 1 resistance in astrocytes by enhancing the PKR antiviral response. J Virol (2005) 1.17
Human immunodeficiency virus type 1 efficiently binds to human fetal astrocytes and induces neuroinflammatory responses independent of infection. BMC Neurosci (2007) 1.08
Gamma interferon primes productive human immunodeficiency virus infection in astrocytes. J Virol (2006) 1.07
Diminished rev-mediated stimulation of human immunodeficiency virus type 1 protein synthesis is a hallmark of human astrocytes. J Virol (1999) 1.06
Expression of exogenous Sam68, the 68-kilodalton SRC-associated protein in mitosis, is able to alleviate impaired Rev function in astrocytes. J Virol (2002) 1.05
Human immunodeficiency virus infection of the brain: pitfalls in evaluating infected/affected cell populations. Brain Pathol (2004) 0.98
Nuclear preservation and cytoplasmic degradation of human immunodeficiency virus type 1 Rev protein. J Virol (1996) 0.90
HIV-1 entry and trans-infection of astrocytes involves CD81 vesicles. PLoS One (2014) 0.90
Astrocyte apoptosis induced by HIV-1 transactivation of the c-kit protooncogene. Proc Natl Acad Sci U S A (1997) 0.88
Identification of a novel Rev-interacting cellular protein. BMC Cell Biol (2005) 0.87
Puralpha as a cellular co-factor of Rev/RRE-mediated expression of HIV-1 intron-containing mRNA. J Cell Biochem (2008) 0.86
The brain-specific factor FEZ1 is a determinant of neuronal susceptibility to HIV-1 infection. Proc Natl Acad Sci U S A (2009) 0.86
Sterile alpha motif and histidine/aspartic acid domain-containing protein 1 (SAMHD1)-facilitated HIV restriction in astrocytes is regulated by miRNA-181a. J Neuroinflammation (2015) 0.86
Role of resident CNS cell populations in HTLV-1-associated neuroinflammatory disease. Front Biosci (Landmark Ed) (2009) 0.84
Cross-interaction between JC virus agnoprotein and human immunodeficiency virus type 1 (HIV-1) Tat modulates transcription of the HIV-1 long terminal repeat in glial cells. J Virol (2006) 0.84
Endocytosis-mediated HIV-1 entry and its significance in the elusive behavior of the virus in astrocytes. Virology (2014) 0.82
A mechanism of restricted human immunodeficiency virus type 1 expression in human glial cells. J Virol (1996) 0.82
Human chromosome 6- and 11-encoded factors support human immunodeficiency virus type 1 Rev function in A9 cells. J Virol (1996) 0.82
Cooperativity among Rev-associated nuclear export signals regulates HIV-1 gene expression and is a determinant of virus species tropism. J Virol (2014) 0.81
Genetic variation and HIV-associated neurologic disease. Adv Virus Res (2013) 0.81
HIV-associated neuropathogenesis: a systems biology perspective for modeling and therapy. Biosystems (2014) 0.80
Cell-cell contact viral transfer contributes to HIV infection and persistence in astrocytes. J Neurovirol (2014) 0.80
The human T-cell leukemia virus type 1 Rex regulatory protein exhibits an impaired functionality in human lymphoblastoid Jurkat T cells. J Virol (1997) 0.79
Mapping the binding interface between an HIV-1 inhibiting intrabody and the viral protein Rev. PLoS One (2013) 0.78
HIV-1 increases TLR responses in human primary astrocytes. Sci Rep (2015) 0.78
Unperturbed posttranscriptional regulatory Rev protein function and HIV-1 replication in astrocytes. PLoS One (2014) 0.78
Impact of viral factors on subcellular distribution and RNA export activity of HIV-1 rev in astrocytes 1321N1. PLoS One (2013) 0.77
HIV-1 endocytosis in astrocytes: a kiss of death or survival of the fittest? Neurosci Res (2014) 0.77
Functional nuclear topography of transcriptionally inducible extra-chromosomal transgene clusters. Chromosome Res (2010) 0.77
A model system for human cytomegalovirus-mediated modulation of human immunodeficiency virus type 1 long terminal repeat activity in brain cells. J Virol (1997) 0.77
Endocytosis of human immunodeficiency virus 1 (HIV-1) in astrocytes: a fiery path to its destination. Microb Pathog (2014) 0.76
Chronic low-level expression of HIV-1 Tat promotes a neurodegenerative phenotype with aging. Sci Rep (2017) 0.75
DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A (1977) 790.54
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry (1979) 180.95
A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology (1973) 127.36
Firefly luciferase gene: structure and expression in mammalian cells. Mol Cell Biol (1987) 26.70
The HIV-1 rev trans-activator acts through a structured target sequence to activate nuclear export of unspliced viral mRNA. Nature (1989) 13.92
HTLV-III expression and production involve complex regulation at the levels of splicing and translation of viral RNA. Cell (1986) 12.74
rev protein of human immunodeficiency virus type 1 affects the stability and transport of the viral mRNA. Proc Natl Acad Sci U S A (1989) 8.76
Evidence for a role of virulent human immunodeficiency virus (HIV) variants in the pathogenesis of acquired immunodeficiency syndrome: studies on sequential HIV isolates. J Virol (1989) 8.32
Functional dissection of the HIV-1 Rev trans-activator--derivation of a trans-dominant repressor of Rev function. Cell (1989) 7.46
Cytokine-induced expression of HIV-1 in a chronically infected promonocyte cell line. Science (1987) 7.22
Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone. Proc Natl Acad Sci U S A (1989) 6.32
The rev gene product of the human immunodeficiency virus affects envelope-specific RNA localization. Cell (1989) 6.13
Pathogenesis of human immunodeficiency virus infection. Microbiol Rev (1993) 5.88
Regulation of human immunodeficiency virus env expression by the rev gene product. J Virol (1989) 5.79
Cloning and functional analysis of multiply spliced mRNA species of human immunodeficiency virus type 1. J Virol (1990) 5.64
An optimized freeze-squeeze method for the recovery of DNA fragments from agarose gels. Anal Biochem (1983) 5.40
The rev (trs/art) protein of human immunodeficiency virus type 1 affects viral mRNA and protein expression via a cis-acting sequence in the env region. J Virol (1989) 5.07
Cells nonproductively infected with HIV-1 exhibit an aberrant pattern of viral RNA expression: a molecular model for latency. Cell (1990) 4.78
Steroid-receptor fusion of the human immunodeficiency virus type 1 Rev transactivator: mapping cryptic functions of the arginine-rich motif. Proc Natl Acad Sci U S A (1990) 4.63
Restricted expression of human T-cell leukemia--lymphoma virus (HTLV) in transformed human umbilical cord blood lymphocytes. Virology (1983) 4.11
Mutational definition of the human immunodeficiency virus type 1 Rev activation domain. J Virol (1991) 3.94
Characterization of a promonocyte clone chronically infected with HIV and inducible by 13-phorbol-12-myristate acetate. J Immunol (1988) 3.45
Distinct RNA sequences in the gag region of human immunodeficiency virus type 1 decrease RNA stability and inhibit expression in the absence of Rev protein. J Virol (1992) 3.44
The HIV-1 Rev trans-activator shuttles between the nucleus and the cytoplasm. Genes Dev (1994) 3.34
Human immunodeficiency virus as a prototypic complex retrovirus. J Virol (1991) 3.19
Tumor necrosis factor alpha functions in an autocrine manner in the induction of human immunodeficiency virus expression. Proc Natl Acad Sci U S A (1990) 3.18
Mutational inactivation of an inhibitory sequence in human immunodeficiency virus type 1 results in Rev-independent gag expression. J Virol (1992) 3.14
Rev is necessary for translation but not cytoplasmic accumulation of HIV-1 vif, vpr, and env/vpu 2 RNAs. Genes Dev (1991) 3.06
The biochemistry of AIDS. Annu Rev Biochem (1991) 3.06
The Rev protein of human immunodeficiency virus type 1 promotes polysomal association and translation of gag/pol and vpu/env mRNAs. Mol Cell Biol (1992) 2.83
Oligomerization and RNA binding domains of the type 1 human immunodeficiency virus Rev protein: a dual function for an arginine-rich binding motif. Proc Natl Acad Sci U S A (1991) 2.66
Heterogeneity of Genotypic and phenotypic characteristics of fifteen permanent cell lines derived from human gliomas. J Neuropathol Exp Neurol (1981) 2.65
Functional analysis of CAR, the target sequence for the Rev protein of HIV-1. Science (1989) 2.62
A human cell factor is essential for HIV-1 Rev action. EMBO J (1990) 2.43
Mutational analysis of the human immunodeficiency virus type 1 Rev transactivator: essential residues near the amino terminus. J Virol (1990) 2.36
T4 positive human neoplastic cell lines susceptible to and permissive for HTLV-III. Lancet (1984) 2.28
Structure-function analyses of the HTLV-I Rex and HIV-1 Rev RNA response elements: insights into the mechanism of Rex and Rev action. Genes Dev (1990) 2.24
Determinants for the establishment of permanent tissue culture lines from human gliomas. Acta Pathol Microbiol Scand A (1973) 2.23
Tat and Rev: positive regulators of HIV gene expression. AIDS (1990) 2.18
Feedback regulation of human immunodeficiency virus type 1 expression by the Rev protein. J Virol (1990) 2.17
Identification of trans-dominant HIV-1 rev protein mutants by direct transfer of bacterially produced proteins into human cells. Nucleic Acids Res (1990) 2.14
Structural and functional characterization of the human immunodeficiency virus rev protein. J Acquir Immune Defic Syndr (1989) 2.10
Specific complex of human immunodeficiency virus type 1 rev and nucleolar B23 proteins: dissociation by the Rev response element. Mol Cell Biol (1991) 2.02
Different sites of interaction for Rev, Tev, and Rex proteins within the Rev-responsive element of human immunodeficiency virus type 1. J Virol (1990) 1.90
Elements distinct from human immunodeficiency virus type 1 splice sites are responsible for the Rev dependence of env mRNA. J Virol (1994) 1.88
HIV-1 infection of subcortical astrocytes in the pediatric central nervous system. Neurology (1994) 1.86
Overexpression of nef as a marker for restricted HIV-1 infection of astrocytes in postmortem pediatric central nervous tissues. Neurology (1994) 1.80
Evidence for neurotoxic activity of tat from human immunodeficiency virus type 1. J Virol (1991) 1.75
Efficient replication of human immunodeficiency virus type 1 requires a threshold level of Rev: potential implications for latency. J Virol (1992) 1.74
Regulation of HIV-1 gene expression. Annu Rev Immunol (1990) 1.66
Mechanism of translation of monocistronic and multicistronic human immunodeficiency virus type 1 mRNAs. Mol Cell Biol (1992) 1.61
Temporal patterns of human immunodeficiency virus type 1 transcripts in human fetal astrocytes. J Virol (1994) 1.50
The HIV-1 Rev protein: a model system for coupled RNA transport and translation. New Biol (1991) 1.50
Induction of human immunodeficiency virus type 1 expression in chronically infected cells is associated primarily with a shift in RNA splicing patterns. J Virol (1991) 1.48
HIV-1 Rev is capable of shuttling between the nucleus and cytoplasm. Virology (1994) 1.45
Binding of trans-dominant mutant Rev protein of human immunodeficiency virus type 1 to the cis-acting Rev-responsive element does not affect the fate of viral mRNA. New Biol (1990) 1.37
The blocks to human immunodeficiency virus type 1 Tat and Rev functions in mouse cell lines are independent. J Virol (1993) 1.34
Sodium butyrate treatment of cells latently infected with HIV-1 results in the expression of unspliced viral RNA. Virology (1993) 1.27
Molecular biology of HIV-1: positive and negative regulatory elements important for virus expression. AIDS (1993) 1.27
HIV-1 latency due to the site of proviral integration. Virology (1993) 1.23
Analysis of Tat function in human immunodeficiency virus type 1-infected low-level-expression cell lines U1 and ACH-2. J Virol (1994) 1.22
Splicing variability in HIV type 1 revealed by quantitative RNA polymerase chain reaction. AIDS Res Hum Retroviruses (1994) 1.20
Negative regulation of human immune deficiency virus replication in monocytes. Distinctions between restricted and latent expression in THP-1 cells. J Exp Med (1990) 1.18
Infection of human brain cells by HIV-1: restricted virus production in chronically infected human glial cell lines. AIDS (1992) 1.11
Cell lines derived from a human myelomonocytic leukaemia. Br J Haematol (1982) 1.09
Cellular localization of Nef expressed in persistently HIV-1-infected low-producer astrocytes. AIDS (1992) 1.03
HIV-1 Nef protein exhibits structural and functional similarity to scorpion peptides interacting with K+ channels. AIDS (1991) 1.02
Infection of human fibroblasts and osteoblast-like cells with HIV-1. AIDS (1990) 1.00
Lethal neurotoxicity in mice of the basic domains of HIV and SIV Rev proteins. Study of these regions by circular dichroism. FEBS Lett (1991) 0.97
Restricted expression of HIV1 in human astrocytes: molecular basis for viral persistence in the CNS. Res Virol (1995) 0.95
Regulated expression of human immunodeficiency virus type 1 in human glial cells: induction of dormant virus. Pathobiology (1992) 0.94
Human immunodeficiency virus type 1 infection of the brain. Clin Microbiol Rev (1993) 0.94
Pathogenesis and therapy of HIV-1 infection of the central nervous system. AIDS (1992) 0.90
Inhibition of human immunodeficiency virus type 1 Rev function by a Rev mutant which interferes with nuclear/nucleolar localization of Rev. J Virol (1992) 0.88
Cellular latency of human immunodeficiency virus type 1. Curr Opin Immunol (1992) 0.86
Transient expression of human immunodeficiency virus type 1 genome results in a nonproductive infection in human fetal dorsal root ganglia glial cells. Virology (1989) 0.82
Tat contains a sequence related to snake neurotoxins. AIDS (1992) 0.81
HPLC purification of PCR products for direct sequencing. Trends Genet (1993) 0.79
rev protein of human immunodeficiency virus type 1 affects the stability and transport of the viral mRNA. Proc Natl Acad Sci U S A (1989) 8.76
The pX protein of HTLV-I is a transcriptional activator of its long terminal repeats. Science (1985) 6.60
TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleus. Mol Cell (1998) 5.85
Cloning and functional analysis of multiply spliced mRNA species of human immunodeficiency virus type 1. J Virol (1990) 5.64
Electroencephalographic signatures of attentional and cognitive default modes in spontaneous brain activity fluctuations at rest. Proc Natl Acad Sci U S A (2003) 5.23
Expression and characterization of the trans-activator of HTLV-III/LAV virus. Science (1986) 5.15
The rev (trs/art) protein of human immunodeficiency virus type 1 affects viral mRNA and protein expression via a cis-acting sequence in the env region. J Virol (1989) 5.07
Distinct RNA sequences in the gag region of human immunodeficiency virus type 1 decrease RNA stability and inhibit expression in the absence of Rev protein. J Virol (1992) 3.44
Env and Vpu proteins of human immunodeficiency virus type 1 are produced from multiple bicistronic mRNAs. J Virol (1990) 3.42
EEG-correlated fMRI of human alpha activity. Neuroimage (2003) 3.34
Inactivation of the human immunodeficiency virus type 1 inhibitory elements allows Rev-independent expression of Gag and Gag/protease and particle formation. J Virol (1997) 3.28
Non-replicating vaccinia vector efficiently expresses bacteriophage T7 RNA polymerase. FEBS Lett (1995) 3.28
Sequence and secondary structure of Drosophila melanogaster 5.8S and 2S rRNAs and of the processing site between them. Nucleic Acids Res (1979) 3.15
Mutational inactivation of an inhibitory sequence in human immunodeficiency virus type 1 results in Rev-independent gag expression. J Virol (1992) 3.14
Cis-acting sequences responsible for the transcriptional activation of human T-cell leukemia virus type I constitute a conditional enhancer. Proc Natl Acad Sci U S A (1986) 3.12
Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles: a mechanism for cellular human immunodeficiency virus 1 infection. Nat Med (2000) 3.10
Regulation of a metallothionein-growth hormone hybrid gene in bovine papilloma virus. Proc Natl Acad Sci U S A (1983) 3.06
A quantitative bioassay for HIV-1 based on trans-activation. Science (1988) 2.99
The Rev protein of human immunodeficiency virus type 1 promotes polysomal association and translation of gag/pol and vpu/env mRNAs. Mol Cell Biol (1992) 2.83
The structural basis for spectral variations in green fluorescent protein. Nat Struct Biol (1997) 2.79
Duplicated heavy metal control sequences of the mouse metallothionein-I gene. Proc Natl Acad Sci U S A (1984) 2.69
Regulation of expression of human immunodeficiency virus. New Biol (1990) 2.60
Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation. EMBO J (1997) 2.57
Improved DNA: liposome complexes for increased systemic delivery and gene expression. Nat Biotechnol (1997) 2.52
Complex splicing in the human T-cell leukemia virus (HTLV) family of retroviruses: novel mRNAs and proteins produced by HTLV type I. J Virol (1992) 2.52
Expression of human immunodeficiency virus type 1 vif and vpr mRNAs is Rev-dependent and regulated by splicing. Virology (1991) 2.43
Nucleoporins nup98 and nup214 participate in nuclear export of human immunodeficiency virus type 1 Rev. J Virol (1999) 2.37
The human poly(A)-binding protein 1 shuttles between the nucleus and the cytoplasm. J Biol Chem (1998) 2.23
Intracellular and surface expression of the HIV-1 coreceptor CXCR4/fusin on various leukocyte subsets: rapid internalization and recycling upon activation. J Immunol (1998) 2.22
Tat and Rev: positive regulators of HIV gene expression. AIDS (1990) 2.18
Feedback regulation of human immunodeficiency virus type 1 expression by the Rev protein. J Virol (1990) 2.17
Identification of trans-dominant HIV-1 rev protein mutants by direct transfer of bacterially produced proteins into human cells. Nucleic Acids Res (1990) 2.14
Identification of novel import and export signals of human TAP, the protein that binds to the constitutive transport element of the type D retrovirus mRNAs. Mol Cell Biol (1999) 2.09
Highly attenuated modified vaccinia virus Ankara replicates in baby hamster kidney cells, a potential host for virus propagation, but not in various human transformed and primary cells. J Gen Virol (1998) 2.06
Dynamic uncoupling and recoupling of perfusion and oxidative metabolism during focal brain activation in man. Magn Reson Med (1996) 2.02
First pass annotation of promoters on human chromosome 22. Genome Res (2001) 1.99
Representation of the temporal envelope of sounds in the human brain. J Neurophysiol (2000) 1.96
Different sites of interaction for Rev, Tev, and Rex proteins within the Rev-responsive element of human immunodeficiency virus type 1. J Virol (1990) 1.90
Elements distinct from human immunodeficiency virus type 1 splice sites are responsible for the Rev dependence of env mRNA. J Virol (1994) 1.88
A novel human immunodeficiency virus type 1 protein, tev, shares sequences with tat, env, and rev proteins. J Virol (1990) 1.87
Where the BOLD signal goes when alpha EEG leaves. Neuroimage (2006) 1.86
The posttranscriptional control element of the simian retrovirus type 1 forms an extensive RNA secondary structure necessary for its function. J Virol (1996) 1.85
The anticancer drug imatinib induces cellular autophagy. Leukemia (2007) 1.84
Astrocytes: HIV cellular reservoirs and important participants in neuropathogenesis. AIDS (1999) 1.84
Disruption of experience-dependent synaptic modifications in striate cortex by infusion of an NMDA receptor antagonist. J Neurosci (1990) 1.77
Competition for cellular factors that activate metallothionein gene transcription. Nature (1985) 1.76
The inducibly expressed GTPase localizes to the endoplasmic reticulum, independently of GTP binding. J Biol Chem (1997) 1.75
A bioassay for HIV-1 based on Env-CD4 interaction. AIDS Res Hum Retroviruses (1990) 1.70
Dissociating neural correlates of cognitive components in mental calculation. Cereb Cortex (2001) 1.69
Development and applications of enhanced green fluorescent protein mutants. Biotechniques (1998) 1.68
Cross-activation of the Rex proteins of HTLV-I and BLV and of the Rev protein of HIV-1 and nonreciprocal interactions with their RNA responsive elements. New Biol (1989) 1.66
Mechanism of translation of monocistronic and multicistronic human immunodeficiency virus type 1 mRNAs. Mol Cell Biol (1992) 1.61
Sex but no hand difference in the isthmus of the corpus callosum. Neurology (1992) 1.60
Identification and characterization of SET, a nuclear phosphoprotein encoded by the translocation break point in acute undifferentiated leukemia. J Biol Chem (1994) 1.57
Intracellular trafficking and interactions of the HIV-1 Tat protein. Virology (1998) 1.57
Contributions of sensory input, auditory search and verbal comprehension to cortical activity during speech processing. Cereb Cortex (2004) 1.53
The mRNA export in Caenorhabditis elegans is mediated by Ce-NXF-1, an ortholog of human TAP/NXF and Saccharomyces cerevisiae Mex67p. RNA (2000) 1.52
Cerebral microembolism in symptomatic and asymptomatic high-grade internal carotid artery stenosis. Neurology (1994) 1.52
Rapidly and slowly replicating human immunodeficiency virus type 1 isolates can be distinguished according to target-cell tropism in T-cell and monocyte cell lines. Proc Natl Acad Sci U S A (1989) 1.51
Human SSAV-related endogenous retroviral element: LTR-like sequence and chromosomal localization to 18q21. Genomics (1989) 1.49
The HIV-1 virion-associated protein vpr is a coactivator of the human glucocorticoid receptor. J Exp Med (1999) 1.43
Evaluation of novel human immunodeficiency virus type 1 Gag DNA vaccines for protein expression in mammalian cells and induction of immune responses. J Virol (1999) 1.43
Noninvasive functional imaging of human brain using light. J Cereb Blood Flow Metab (2000) 1.41
Abnormal RNA splicing causes one form of alpha thalassemia. Cell (1982) 1.41
Significance of restricted HIV expression for HIV neuropathogenesis: still an unresolved issue. AIDS (1997) 1.41
A group model for stable multi-subject ICA on fMRI datasets. Neuroimage (2010) 1.41
Expression of two human growth hormone genes in monkey cells infected by simian virus 40 recombinants. Proc Natl Acad Sci U S A (1981) 1.39
Virions released from cells transfected with a molecular clone of human T-cell leukemia virus type I give rise to primary and secondary infections of T cells. J Virol (1995) 1.37
Binding of trans-dominant mutant Rev protein of human immunodeficiency virus type 1 to the cis-acting Rev-responsive element does not affect the fate of viral mRNA. New Biol (1990) 1.37
Antimicrobial peptides melittin and cecropin inhibit replication of human immunodeficiency virus 1 by suppressing viral gene expression. J Gen Virol (1998) 1.36