Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 A resolution.
|
Nature
|
1981
|
24.17
|
2
|
Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin.
|
Annu Rev Biochem
|
2000
|
19.03
|
3
|
Atomic structure of the ectodomain from HIV-1 gp41.
|
Nature
|
1997
|
16.31
|
4
|
Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation.
|
Nature
|
1981
|
15.85
|
5
|
Structure of influenza haemagglutinin at the pH of membrane fusion.
|
Nature
|
1994
|
14.61
|
6
|
Structure of the human class I histocompatibility antigen, HLA-A2.
|
Nature
|
1987
|
14.54
|
7
|
The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens.
|
Nature
|
1987
|
12.43
|
8
|
The structure and function of the hemagglutinin membrane glycoprotein of influenza virus.
|
Annu Rev Biochem
|
1987
|
11.99
|
9
|
Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1.
|
Nature
|
1993
|
8.75
|
10
|
Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid.
|
Nature
|
1988
|
8.32
|
11
|
Single amino acid substitutions in influenza haemagglutinin change receptor binding specificity.
|
Nature
|
1983
|
8.28
|
12
|
The structure and receptor binding properties of the 1918 influenza hemagglutinin.
|
Science
|
2004
|
7.74
|
13
|
Changes in the conformation of influenza virus hemagglutinin at the pH optimum of virus-mediated membrane fusion.
|
Proc Natl Acad Sci U S A
|
1982
|
7.34
|
14
|
Crystal structure of the human class II MHC protein HLA-DR1 complexed with an influenza virus peptide.
|
Nature
|
1994
|
7.13
|
15
|
Structure of the complex between human T-cell receptor, viral peptide and HLA-A2.
|
Nature
|
1996
|
6.20
|
16
|
A hypothetical model of the foreign antigen binding site of class II histocompatibility molecules.
|
Nature
|
1988
|
5.99
|
17
|
X-ray structures of H5 avian and H9 swine influenza virus hemagglutinins bound to avian and human receptor analogs.
|
Proc Natl Acad Sci U S A
|
2001
|
5.92
|
18
|
HLA-A2-peptide complexes: refolding and crystallization of molecules expressed in Escherichia coli and complexed with single antigenic peptides.
|
Proc Natl Acad Sci U S A
|
1992
|
5.02
|
19
|
Identification of self peptides bound to purified HLA-B27.
|
Nature
|
1991
|
4.88
|
20
|
Fusion mutants of the influenza virus hemagglutinin glycoprotein.
|
Cell
|
1985
|
4.84
|
21
|
Crystal structure of the Ebola virus membrane fusion subunit, GP2, from the envelope glycoprotein ectodomain.
|
Mol Cell
|
1998
|
4.73
|
22
|
Herpes simplex virus glycoprotein D bound to the human receptor HveA.
|
Mol Cell
|
2001
|
4.44
|
23
|
Refined structure of the human histocompatibility antigen HLA-A2 at 2.6 A resolution.
|
J Mol Biol
|
1991
|
4.44
|
24
|
A carbohydrate side chain on hemagglutinins of Hong Kong influenza viruses inhibits recognition by a monoclonal antibody.
|
Proc Natl Acad Sci U S A
|
1984
|
4.37
|
25
|
Specificity pockets for the side chains of peptide antigens in HLA-Aw68.
|
Nature
|
1989
|
4.34
|
26
|
Coiled coils in both intracellular vesicle and viral membrane fusion.
|
Cell
|
1998
|
4.26
|
27
|
N- and C-terminal residues combine in the fusion-pH influenza hemagglutinin HA(2) subunit to form an N cap that terminates the triple-stranded coiled coil.
|
Proc Natl Acad Sci U S A
|
1999
|
3.90
|
28
|
The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation.
|
Nature
|
1991
|
3.84
|
29
|
Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle.
|
Nature
|
1992
|
3.82
|
30
|
Selection of gp41-mediated HIV-1 cell entry inhibitors from biased combinatorial libraries of non-natural binding elements.
|
Nat Struct Biol
|
1999
|
3.72
|
31
|
Structure of the hemagglutinin precursor cleavage site, a determinant of influenza pathogenicity and the origin of the labile conformation.
|
Cell
|
1998
|
3.69
|
32
|
Three-dimensional structure of a human class II histocompatibility molecule complexed with superantigen.
|
Nature
|
1994
|
3.60
|
33
|
The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2.
|
Cell
|
1993
|
3.44
|
34
|
Analyses of the antigenicity of influenza haemagglutinin at the pH optimum for virus-mediated membrane fusion.
|
J Gen Virol
|
1983
|
3.43
|
35
|
The three-dimensional structure of HLA-B27 at 2.1 A resolution suggests a general mechanism for tight peptide binding to MHC.
|
Cell
|
1992
|
3.27
|
36
|
Structural basis for membrane fusion by enveloped viruses.
|
Mol Membr Biol
|
1999
|
3.26
|
37
|
Atomic structure of a human MHC molecule presenting an influenza virus peptide.
|
Nature
|
1992
|
3.12
|
38
|
The receptor-binding and membrane-fusion properties of influenza virus variants selected using anti-haemagglutinin monoclonal antibodies.
|
EMBO J
|
1987
|
3.03
|
39
|
Binding of influenza virus hemagglutinin to analogs of its cell-surface receptor, sialic acid: analysis by proton nuclear magnetic resonance spectroscopy and X-ray crystallography.
|
Biochemistry
|
1992
|
3.03
|
40
|
The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3.
|
Nature
|
1995
|
2.90
|
41
|
Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical.
|
Immunity
|
1999
|
2.86
|
42
|
The human class II MHC protein HLA-DR1 assembles as empty alpha beta heterodimers in the absence of antigenic peptide.
|
Cell
|
1992
|
2.79
|
43
|
Studies with crosslinking reagents on the oligomeric structure of the env glycoprotein of HIV.
|
Virology
|
1989
|
2.74
|
44
|
Refinement of the influenza virus hemagglutinin by simulated annealing.
|
J Mol Biol
|
1990
|
2.61
|
45
|
Crystal structure of the human natural killer cell inhibitory receptor KIR2DL1-HLA-Cw4 complex.
|
Nat Immunol
|
2001
|
2.52
|
46
|
Binding of the influenza A virus to cell-surface receptors: structures of five hemagglutinin-sialyloligosaccharide complexes determined by X-ray crystallography.
|
Virology
|
1997
|
2.51
|
47
|
Introduction of intersubunit disulfide bonds in the membrane-distal region of the influenza hemagglutinin abolishes membrane fusion activity.
|
Cell
|
1992
|
2.47
|
48
|
Crystal and molecular structures of native and CTP-liganded aspartate carbamoyltransferase from Escherichia coli.
|
J Mol Biol
|
1982
|
2.46
|
49
|
Peptide binding to HLA-DR1: a peptide with most residues substituted to alanine retains MHC binding.
|
EMBO J
|
1990
|
2.42
|
50
|
Structure of the haemagglutinin-esterase-fusion glycoprotein of influenza C virus.
|
Nature
|
1998
|
2.41
|
51
|
Crystallographic determination of symmetry of aspartate transcarbamylase.
|
Nature
|
1968
|
2.37
|
52
|
Structure of a human insulin peptide-HLA-DQ8 complex and susceptibility to type 1 diabetes.
|
Nat Immunol
|
2001
|
2.34
|
53
|
Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids.
|
Immunity
|
1998
|
2.31
|
54
|
A soluble domain of the membrane-anchoring chain of influenza virus hemagglutinin (HA2) folds in Escherichia coli into the low-pH-induced conformation.
|
Proc Natl Acad Sci U S A
|
1995
|
2.24
|
55
|
Hemagglutinins from two influenza virus variants bind to sialic acid derivatives with millimolar dissociation constants: a 500-MHz proton nuclear magnetic resonance study.
|
Biochemistry
|
1989
|
2.24
|
56
|
Toxic shock syndrome toxin-1 complexed with a class II major histocompatibility molecule HLA-DR1.
|
Science
|
1994
|
2.24
|
57
|
The ectodomain of HIV-1 env subunit gp41 forms a soluble, alpha-helical, rod-like oligomer in the absence of gp120 and the N-terminal fusion peptide.
|
EMBO J
|
1996
|
2.21
|
58
|
Studies on the structure of the influenza virus haemagglutinin at the pH of membrane fusion.
|
J Gen Virol
|
1988
|
2.21
|
59
|
Conformational changes in the hemagglutinin of influenza virus which accompany heat-induced fusion of virus with liposomes.
|
Virology
|
1986
|
2.13
|
60
|
X-ray crystal structure of HLA-DR4 (DRA*0101, DRB1*0401) complexed with a peptide from human collagen II.
|
Immunity
|
1997
|
2.07
|
61
|
alpha beta T cell receptor ligand-specific oligomerization revisited.
|
Immunity
|
2001
|
2.04
|
62
|
Cleavage of the human respiratory syncytial virus fusion protein at two distinct sites is required for activation of membrane fusion.
|
Proc Natl Acad Sci U S A
|
2001
|
2.04
|
63
|
Structure of a covalently stabilized complex of a human alphabeta T-cell receptor, influenza HA peptide and MHC class II molecule, HLA-DR1.
|
EMBO J
|
2000
|
2.00
|
64
|
Studies on the adaptation of influenza viruses to MDCK cells.
|
EMBO J
|
1984
|
1.98
|
65
|
Studies of the membrane fusion activities of fusion peptide mutants of influenza virus hemagglutinin.
|
J Virol
|
1995
|
1.96
|
66
|
Studies of the binding properties of influenza hemagglutinin receptor-site mutants.
|
Virology
|
1998
|
1.95
|
67
|
Crystal structure of HLA-DR2 (DRA*0101, DRB1*1501) complexed with a peptide from human myelin basic protein.
|
J Exp Med
|
1998
|
1.94
|
68
|
Evidence from studies with a cross-linking reagent that the haemagglutinin of influenza virus is a trimer.
|
Virology
|
1977
|
1.93
|
69
|
Host-mediated selection of influenza virus receptor variants. Sialic acid-alpha 2,6Gal-specific clones of A/duck/Ukraine/1/63 revert to sialic acid-alpha 2,3Gal-specific wild type in ovo.
|
J Biol Chem
|
1985
|
1.91
|
70
|
Structure of the ABC ATPase domain of human TAP1, the transporter associated with antigen processing.
|
EMBO J
|
2001
|
1.91
|
71
|
Sequential mutations in hemagglutinins of influenza B virus isolates: definition of antigenic domains.
|
Proc Natl Acad Sci U S A
|
1983
|
1.88
|
72
|
Electron microscopy of the human respiratory syncytial virus fusion protein and complexes that it forms with monoclonal antibodies.
|
Virology
|
2000
|
1.87
|
73
|
Structural characterization of a soluble and partially folded class I major histocompatibility heavy chain/beta 2m heterodimer.
|
Nat Struct Biol
|
1998
|
1.82
|
74
|
Amantadine selection of a mutant influenza virus containing an acid-stable hemagglutinin glycoprotein: evidence for virus-specific regulation of the pH of glycoprotein transport vesicles.
|
Proc Natl Acad Sci U S A
|
1991
|
1.79
|
75
|
Binary and ternary complexes between T-cell receptor, class II MHC and superantigen in vitro.
|
Nature
|
1994
|
1.79
|
76
|
Studies of influenza haemagglutinin-mediated membrane fusion.
|
Virology
|
1986
|
1.78
|
77
|
Crystal structures of two closely related but antigenically distinct HLA-A2/melanocyte-melanoma tumor-antigen peptide complexes.
|
J Immunol
|
2001
|
1.77
|
78
|
A structural motif in the variant surface glycoproteins of Trypanosoma brucei.
|
Nature
|
1993
|
1.77
|
79
|
Evidence that multiple residues on both the alpha-helices of the class I MHC molecule are simultaneously recognized by the T cell receptor.
|
Cell
|
1988
|
1.77
|
80
|
Electron microscopy of antibody complexes of influenza virus haemagglutinin in the fusion pH conformation.
|
EMBO J
|
1995
|
1.74
|
81
|
The structure and stability of an HLA-A*0201/octameric tax peptide complex with an empty conserved peptide-N-terminal binding site.
|
J Immunol
|
2000
|
1.74
|
82
|
Three-dimensional structure of an antigenic mutant of the influenza virus haemagglutinin.
|
Nature
|
1984
|
1.72
|
83
|
Antigenic peptide binding by class I and class II histocompatibility proteins.
|
Structure
|
1994
|
1.71
|
84
|
Receptor-binding characteristics of monoclonal antibody-selected antigenic variants of influenza virus.
|
J Virol
|
1987
|
1.70
|
85
|
Membrane fusion by peptide analogues of influenza virus haemagglutinin.
|
J Gen Virol
|
1988
|
1.69
|
86
|
Comparative analyses of the specificities of anti-influenza hemagglutinin antibodies in human sera.
|
J Virol
|
1986
|
1.65
|
87
|
Antigenic analyses of influenza virus haemagglutinins with different receptor-binding specificities.
|
Virology
|
1984
|
1.64
|
88
|
Antigen presentation subverted: Structure of the human cytomegalovirus protein US2 bound to the class I molecule HLA-A2.
|
Proc Natl Acad Sci U S A
|
2001
|
1.60
|
89
|
Assembly, specific binding, and crystallization of a human TCR-alphabeta with an antigenic Tax peptide from human T lymphotropic virus type 1 and the class I MHC molecule HLA-A2.
|
J Immunol
|
1996
|
1.59
|
90
|
The central structural feature of the membrane fusion protein subunit from the Ebola virus glycoprotein is a long triple-stranded coiled coil.
|
Proc Natl Acad Sci U S A
|
1998
|
1.58
|
91
|
Importance of peptide amino and carboxyl termini to the stability of MHC class I molecules.
|
Science
|
1994
|
1.58
|
92
|
Reconstitution by MHC-restricted peptides of HLA-A2 heavy chain with beta 2-microglobulin, in vitro.
|
Nature
|
1991
|
1.55
|
93
|
The structure of HLA-DM, the peptide exchange catalyst that loads antigen onto class II MHC molecules during antigen presentation.
|
Immunity
|
1998
|
1.53
|
94
|
Structure of the inhibitory receptor for human natural killer cells resembles haematopoietic receptors.
|
Nature
|
1997
|
1.53
|
95
|
Structure of the human class I histocompatibility antigen, HLA-A2.
|
J Immunol
|
2005
|
1.52
|
96
|
Deacylation of the hemagglutinin of influenza A/Aichi/2/68 has no effect on membrane fusion properties.
|
Virology
|
1991
|
1.50
|
97
|
MHC class II function preserved by low-affinity peptide interactions preceding stable binding.
|
Nature
|
1994
|
1.50
|
98
|
Conversion of a T cell antagonist into an agonist by repairing a defect in the TCR/peptide/MHC interface: implications for TCR signaling.
|
Immunity
|
2000
|
1.48
|
99
|
Truncated variants of gp120 bind CD4 with high affinity and suggest a minimum CD4 binding region.
|
EMBO J
|
1992
|
1.47
|
100
|
Studies using double mutants of the conformational transitions in influenza hemagglutinin required for its membrane fusion activity.
|
Proc Natl Acad Sci U S A
|
1996
|
1.43
|
101
|
Crystallographic analysis of endogenous peptides associated with HLA-DR1 suggests a common, polyproline II-like conformation for bound peptides.
|
Proc Natl Acad Sci U S A
|
1996
|
1.42
|
102
|
The 5.5 Angstrom resolution structure of the regulatory enzyme, asparate transcarbamylase.
|
Cold Spring Harb Symp Quant Biol
|
1972
|
1.41
|
103
|
Assembly of a rod-shaped chimera of a trimeric GCN4 zipper and the HIV-1 gp41 ectodomain expressed in Escherichia coli.
|
Proc Natl Acad Sci U S A
|
1997
|
1.35
|
104
|
T cell receptor-MHC interactions up close.
|
Cell
|
2001
|
1.31
|
105
|
Structure of a soluble secreted chemokine inhibitor vCCI (p35) from cowpox virus.
|
Proc Natl Acad Sci U S A
|
1999
|
1.29
|
106
|
A surface plasmon resonance assay for the binding of influenza virus hemagglutinin to its sialic acid receptor.
|
Virology
|
1996
|
1.29
|
107
|
Crystallographic detection of a second ligand binding site in influenza virus hemagglutinin.
|
Proc Natl Acad Sci U S A
|
1992
|
1.27
|
108
|
Expression, purification, and characterization of gp160e, the soluble, trimeric ectodomain of the simian immunodeficiency virus envelope glycoprotein, gp160.
|
J Biol Chem
|
2000
|
1.26
|
109
|
Antigenic and amino acid sequence variations in the haemagglutinins of type A influenza viruses recently isolated from human subjects.
|
Bull World Health Organ
|
1983
|
1.26
|
110
|
Three-dimensional structure of a peptide extending from one end of a class I MHC binding site.
|
Nature
|
1994
|
1.26
|
111
|
Amino acid sequences of haemagglutinins of influenza viruses of the H3 subtype isolated from horses.
|
J Gen Virol
|
1985
|
1.26
|
112
|
Crystal structures of influenza virus hemagglutinin in complex with high-affinity receptor analogs.
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Structure
|
1994
|
1.24
|
113
|
Studies on influenza haemagglutinin fusion peptide mutants generated by reverse genetics.
|
EMBO J
|
2001
|
1.23
|
114
|
Temperature dependence of fusion by sendai virus.
|
Virology
|
2000
|
1.23
|
115
|
Antigenic and amino acid sequence analyses of influenza viruses of the H1N1 subtype isolated between 1982 and 1984.
|
Bull World Health Organ
|
1985
|
1.21
|
116
|
Adaptation of egg-grown and transfectant influenza viruses for growth in mammalian cells: selection of hemagglutinin mutants with elevated pH of membrane fusion.
|
Virology
|
1997
|
1.20
|
117
|
Crystallization and X-ray diffraction studies on the histocompatibility antigens HLA-A2 and HLA-A28 from human cell membranes.
|
J Mol Biol
|
1985
|
1.18
|
118
|
Peptide recognition by two HLA-A2/Tax11-19-specific T cell clones in relationship to their MHC/peptide/TCR crystal structures.
|
J Immunol
|
1999
|
1.18
|
119
|
HOOK: a program for finding novel molecular architectures that satisfy the chemical and steric requirements of a macromolecule binding site.
|
Proteins
|
1994
|
1.17
|
120
|
Ligand recognition by influenza virus. The binding of bivalent sialosides.
|
J Biol Chem
|
1991
|
1.15
|
121
|
Identification of a crucial energetic footprint on the alpha1 helix of human histocompatibility leukocyte antigen (HLA)-A2 that provides functional interactions for recognition by tax peptide/HLA-A2-specific T cell receptors.
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J Exp Med
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2001
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1.15
|
122
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Aspartate transcarbamoylase from Escherichia coli: electron density at 5.5 A resolution.
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Proc Natl Acad Sci U S A
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1973
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1.14
|
123
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Protein, DNA, and virus crystallography with a focused imaging proportional counter.
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Science
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1986
|
1.12
|
124
|
Crystallization and preliminary X-ray diffraction studies of the human major histocompatibility antigen HLA-B27.
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Proteins
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1992
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1.11
|
125
|
The structure of a membrane fusion mutant of the influenza virus haemagglutinin.
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EMBO J
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1990
|
1.11
|
126
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Conformational aspects of the acid-induced fusion mechanism of influenza virus hemagglutinin. Circular dichroism and fluorescence studies.
|
J Biol Chem
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1988
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1.11
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127
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Membrane fusion by influenza hemagglutinin.
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Cold Spring Harb Symp Quant Biol
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1995
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1.10
|
128
|
Proton nuclear magnetic resonance studies of the binding of sialosides to intact influenza virus.
|
Virology
|
1992
|
1.10
|
129
|
Expression and crystallization of the complex of HLA-DR2 (DRA, DRB1*1501) and an immunodominant peptide of human myelin basic protein.
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Proc Natl Acad Sci U S A
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1998
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1.09
|
130
|
Direct binding of a soluble natural killer cell inhibitory receptor to a soluble human leukocyte antigen-Cw4 class I major histocompatibility complex molecule.
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Proc Natl Acad Sci U S A
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1996
|
1.09
|
131
|
Two variant surface glycoproteins of Trypanosoma brucei of different sequence classes have similar 6 A resolution X-ray structures.
|
Nature
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1987
|
1.07
|
132
|
The structure and role of the carbohydrate moieties of influenza virus haemagglutinin.
|
Biochem Soc Trans
|
1983
|
1.05
|
133
|
Influenza fusion peptides.
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Biochem Soc Trans
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2001
|
1.05
|
134
|
Comparison of the P2 specificity pocket in three human histocompatibility antigens: HLA-A*6801, HLA-A*0201, and HLA-B*2705.
|
Proc Natl Acad Sci U S A
|
1993
|
1.04
|
135
|
Zinc-dependent dimers observed in crystals of human endostatin.
|
Proc Natl Acad Sci U S A
|
1998
|
1.03
|
136
|
Structure of a trimeric domain of the MHC class II-associated chaperonin and targeting protein Ii.
|
EMBO J
|
1998
|
1.03
|
137
|
Electron microscopy of influenza haemagglutinin-monoclonal antibody complexes.
|
Virology
|
1983
|
1.01
|
138
|
6 A-resolution X-ray structure of a variable surface glycoprotein from Trypanosoma brucei.
|
Nature
|
1984
|
1.00
|
139
|
Structure of human histocompatibility leukocyte antigen (HLA)-Cw4, a ligand for the KIR2D natural killer cell inhibitory receptor.
|
J Exp Med
|
1999
|
0.98
|
140
|
Invariant chain made in Escherichia coli has an exposed N-terminal segment that blocks antigen binding to HLA-DR1 and a trimeric C-terminal segment that binds empty HLA-DR1.
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Proc Natl Acad Sci U S A
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1995
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0.98
|
141
|
Crystallization and x-ray diffraction studies on the haemagglutinin glycoprotein from the membrane of influenza virus.
|
J Mol Biol
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1977
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0.97
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142
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The structure of aspartate transcarbamylase, I. A molecular twofold axis in the complex with cytidine triphosphate.
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Proc Natl Acad Sci U S A
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1967
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0.95
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143
|
Overexpression of native human beta 2-microglobulin in Escherichia coli and its purification.
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Gene
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1989
|
0.94
|
144
|
Phosphorylated T cell receptor zeta-chain and ZAP70 tandem SH2 domains form a 1:3 complex in vitro.
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Eur J Biochem
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1996
|
0.94
|
145
|
Cobalt-mediated dimerization of the human natural killer cell inhibitory receptor.
|
J Biol Chem
|
2000
|
0.94
|
146
|
Influenza viruses and cell membranes.
|
Am J Respir Crit Care Med
|
1995
|
0.94
|
147
|
The structure of an HIV-1 specific cell entry inhibitor in complex with the HIV-1 gp41 trimeric core.
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