Ian S Young

Author PubWeight™ 134.12‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Prevalence of age-related maculopathy in older Europeans: the European Eye Study (EUREYE). Arch Ophthalmol 2006 2.82
2 Vitamins C and E for prevention of pre-eclampsia in women with type 1 diabetes (DAPIT): a randomised placebo-controlled trial. Lancet 2010 2.78
3 Total synthesis of palau'amine. Angew Chem Int Ed Engl 2010 2.62
4 Novel biomarkers in early diagnosis of acute myocardial infarction compared with cardiac troponin T. Eur Heart J 2008 2.15
5 Oxidative-nitrosative stress and systemic vascular function in highlanders with and without exaggerated hypoxemia. Chest 2013 2.03
6 Clustering of metabolic syndrome risk factors and arterial stiffness in young adults: the Northern Ireland Young Hearts Project. J Hypertens 2007 1.84
7 Genetic and nutritional factors contributing to hyperhomocysteinemia in young adults. Blood 2003 1.57
8 Prediction of Recurrent Events by D-Dimer and Inflammatory Markers in Patients with Normal Cardiac Troponin I (PREDICT) Study. Am Heart J 2003 1.54
9 Prognostic value of a multimarker approach for patients presenting to hospital with acute chest pain. Am J Cardiol 2008 1.53
10 C-reactive protein (CRP) elevation in patients with abdominal aortic aneurysm is independent of the most important CRP genetic polymorphism. J Vasc Surg 2008 1.48
11 Troponin T is an independent predictor of mortality in renal transplant recipients. Nephrol Dial Transplant 2007 1.45
12 Randomized controlled trial assessing the effect of simvastatin in primary biliary cirrhosis. Liver Int 2013 1.45
13 Antioxidants and oxidative stress in BAL fluid of atopic asthmatic children. Pediatr Res 2003 1.45
14 Total synthesis of (+/-)-axinellamines A and B. Angew Chem Int Ed Engl 2008 1.44
15 The role of smoking in abdominal aortic aneurysm development. Angiology 2008 1.41
16 Ascorbic acid reduces blood pressure and arterial stiffness in type 2 diabetes. Hypertension 2002 1.40
17 Synthesis of 1,9-dideoxy-pre-axinellamine. Angew Chem Int Ed Engl 2008 1.39
18 Reproducibility and validity of a food frequency questionnaire among pregnant women in a Mediterranean area. Nutr J 2013 1.34
19 Total syntheses of (+/-)-massadine and massadine chloride. J Am Chem Soc 2008 1.26
20 Enantioselective total syntheses of (-)-palau'amine, (-)-axinellamines, and (-)-massadines. J Am Chem Soc 2011 1.25
21 Free radical-mediated damage to barrier function is not associated with altered brain morphology in high-altitude headache. J Cereb Blood Flow Metab 2006 1.22
22 Sunlight exposure, antioxidants, and age-related macular degeneration. Arch Ophthalmol 2008 1.21
23 Inflammation markers are associated with cardiovascular diseases risk in adolescents: the Young Hearts project 2000. J Adolesc Health 2010 1.20
24 Randomised controlled trial of home-based walking programmes at and below current recommended levels of exercise in sedentary adults. J Epidemiol Community Health 2007 1.19
25 Variations in apolipoprotein E frequency with age in a pooled analysis of a large group of older people. Am J Epidemiol 2011 1.19
26 Evidence of association of APOE with age-related macular degeneration: a pooled analysis of 15 studies. Hum Mutat 2011 1.17
27 Increased cerebral output of free radicals during hypoxia: implications for acute mountain sickness? Am J Physiol Regul Integr Comp Physiol 2009 1.16
28 Regulation of free radical outflow from an isolated muscle bed in exercising humans. Am J Physiol Heart Circ Physiol 2004 1.14
29 Saturated and trans fatty acids and coronary heart disease. Curr Atheroscler Rep 2008 1.14
30 High-altitude pulmonary hypertension is associated with a free radical-mediated reduction in pulmonary nitric oxide bioavailability. J Physiol 2010 1.14
31 High density lipoprotein subfractions: isolation, composition, and their duplicitous role in oxidation. J Lipid Res 2006 1.13
32 Plasma concentrations of carotenoids and vitamin C are better correlated with dietary intake in normal weight than overweight and obese elderly subjects. Br J Nutr 2007 1.09
33 EPR spectroscopic detection of free radical outflow from an isolated muscle bed in exercising humans. J Appl Physiol (1985) 2003 1.09
34 Electron paramagnetic spectroscopic evidence of exercise-induced free radical accumulation in human skeletal muscle. Free Radic Res 2007 1.08
35 Bilirubin and coronary heart disease risk in the Prospective Epidemiological Study of Myocardial Infarction (PRIME). Eur J Cardiovasc Prev Rehabil 2007 1.07
36 Dietary intake of fruits and vegetables improves microvascular function in hypertensive subjects in a dose-dependent manner. Circulation 2009 1.07
37 Genetic screening protocol for familial hypercholesterolemia which includes splicing defects gives an improved mutation detection rate. Atherosclerosis 2005 1.07
38 Micronutrients: dietary intake v. supplement use. Proc Nutr Soc 2005 1.05
39 Effect of eucaloric high- and low-sucrose diets with identical macronutrient profile on insulin resistance and vascular risk: a randomized controlled trial. Diabetes 2006 1.03
40 Blood levels of vitamin C, carotenoids and retinol are inversely associated with cataract in a North Indian population. Invest Ophthalmol Vis Sci 2008 1.03
41 Optimal glycemic control, pre-eclampsia, and gestational hypertension in women with type 1 diabetes in the diabetes and pre-eclampsia intervention trial. Diabetes Care 2011 1.02
42 Paraoxonase polymorphisms PON1 192 and 55 and longevity in Italian centenarians and Irish nonagenarians. A pooled analysis. Exp Gerontol 2004 1.01
43 SNPs at the APOA5 gene account for the strong association with hypertriglyceridaemia at the APOA5/A4/C3/A1 locus on chromosome 11q23 in the Northern Irish population. Atherosclerosis 2005 1.01
44 Low-fat versus low-carbohydrate weight reduction diets: effects on weight loss, insulin resistance, and cardiovascular risk: a randomized control trial. Diabetes 2009 1.01
45 Elevated serum phosphate predicts mortality in renal transplant recipients. Transplantation 2009 1.00
46 Sedentary aging increases resting and exercise-induced intramuscular free radical formation. J Appl Physiol (1985) 2010 0.99
47 Biomarkers of fruit and vegetable intake in human intervention studies: a systematic review. Crit Rev Food Sci Nutr 2011 0.94
48 Exercise, free radicals, and lipid peroxidation in type 1 diabetes mellitus. Free Radic Biol Med 2002 0.94
49 The reduced folate carrier (SLC19A1) c.80G>A polymorphism is associated with red cell folate concentrations among women. Ann Hum Genet 2009 0.94
50 A posteriori dietary patterns are related to risk of type 2 diabetes: findings from a systematic review and meta-analysis. J Acad Nutr Diet 2014 0.93
51 An insertion/deletion polymorphism of the dihydrofolate reductase (DHFR) gene is associated with serum and red blood cell folate concentrations in women. Hum Genet 2008 0.93
52 Fruit and vegetable intake and risk of cardiovascular disease. Proc Nutr Soc 2013 0.92
53 A possible role for the PPARG Pro12Ala polymorphism in preterm birth. Diabetes 2007 0.91
54 Vitamin C prophylaxis promotes oxidative lipid damage during surgical ischemia-reperfusion. Free Radic Biol Med 2005 0.91
55 Prevalence and risk factors for vitamin C deficiency in north and south India: a two centre population based study in people aged 60 years and over. PLoS One 2011 0.91
56 Insulin sensitivity and clustering of coronary heart disease risk factors in young adults. The Northern Ireland Young Hearts Study. Prev Med 2005 0.91
57 Effect of fruit and vegetable consumption on immune function in older people: a randomized controlled trial. Am J Clin Nutr 2012 0.89
58 Genetic evidence that nitric oxide modulates homocysteine: the NOS3 894TT genotype is a risk factor for hyperhomocystenemia. Arterioscler Thromb Vasc Biol 2003 0.89
59 Conduit artery structure and function in lowlanders and native highlanders: relationships with oxidative stress and role of sympathoexcitation. J Physiol 2013 0.89
60 The 5,10-methylenetetrahydrofolate reductase C677T polymorphism interacts with smoking to increase homocysteine. Atherosclerosis 2004 0.88
61 Effect of a Web-Based Behavior Change Program on Weight Loss and Cardiovascular Risk Factors in Overweight and Obese Adults at High Risk of Developing Cardiovascular Disease: Randomized Controlled Trial. J Med Internet Res 2015 0.88
62 Inverse association of vitamin C with cataract in older people in India. Ophthalmology 2011 0.88
63 Lipoprotein composition in HNF1A-MODY: differentiating between HNF1A-MODY and type 2 diabetes. Clin Chim Acta 2012 0.88
64 Oxidative stress and inflammation in lean and obese subjects with polycystic ovary syndrome. J Reprod Med 2013 0.88
65 Retinal vein occlusion, homocysteine, and methylene tetrahydrofolate reductase genotype. Invest Ophthalmol Vis Sci 2005 0.88
66 Lycopene intervention reduces inflammation and improves HDL functionality in moderately overweight middle-aged individuals. J Nutr Biochem 2012 0.88
67 Fruits and vegetables: measuring intake and encouraging increased consumption. Proc Nutr Soc 2013 0.88
68 Pretreatment with intravenous ascorbic acid preserves endothelial function during acute hyperglycaemia (R1). Clin Exp Pharmacol Physiol 2005 0.87
69 Epr spectroscopic evidence of free radical outflow from an isolated muscle bed in exercising humans: functional significance of decreasing intracellular PO2 vs. increasing O2 flux. Adv Exp Med Biol 2003 0.86
70 Primary biliary cirrhosis is associated with oxidative stress and endothelial dysfunction but not increased cardiovascular risk. Hepatol Res 2010 0.86
71 Antioxidants and periodontitis in 60-70-year-old men. J Clin Periodontol 2009 0.86
72 The thymidylate synthase tandem repeat polymorphism is not associated with homocysteine concentrations in healthy young subjects. Hum Genet 2003 0.86
73 Evaluating the effects of a low volume stairclimbing programme on measures of health-related fitness in sedentary office workers. J Sports Sci Med 2007 0.85
74 Evidence for sex differences in the determinants of homocysteine concentrations. Mol Genet Metab 2008 0.85
75 The role of angiogenic and antiangiogenic factors in the second trimester in the prediction of preeclampsia in pregnant women with type 1 diabetes. Diabetes Care 2013 0.85
76 ARMS2 increases the risk of early and late age-related macular degeneration in the European Eye Study. Ophthalmology 2012 0.84
77 Familial combined hyperlipidaemia: under - defined and under - diagnosed? Curr Vasc Pharmacol 2008 0.84
78 Dose-response effect of fruit and vegetables on insulin resistance in people at high risk of cardiovascular disease: a randomized controlled trial. Diabetes Care 2013 0.83
79 Genetic screening of the LPL gene in hypertriglyceridaemic patients. Atherosclerosis 2008 0.83
80 Resting energy expenditure in non-ventilated, non-sedated patients recovering from serious traumatic brain injury: comparison of prediction equations with indirect calorimetry values. Clin Nutr 2009 0.83
81 Effect of increased fruit and vegetable consumption on physical function and muscle strength in older adults. Age (Dordr) 2013 0.83
82 Increased circulating CC chemokine levels in the metabolic syndrome are reduced by low-dose atorvastatin treatment: evidence from a randomized controlled trial. Clin Endocrinol (Oxf) 2013 0.83
83 Plasma clusterin levels and the rs11136000 genotype in individuals with mild cognitive impairment and Alzheimer's disease. Curr Alzheimer Res 2013 0.83
84 Retroperitoneal repair of abdominal aortic aneurysm reduces bowel dysfunction. Vasc Endovascular Surg 2009 0.83
85 Influence of the cystathionine beta-synthase 844ins68 and methylenetetrahydrofolate reductase 677C>T polymorphisms on folate and homocysteine concentrations. Eur J Hum Genet 2008 0.83
86 Dietary patterns and bone mineral status in young adults: the Northern Ireland Young Hearts Project. Br J Nutr 2012 0.83
87 Methylprednisolone increases urinary nitrate concentrations and reduces subclinical renal injury during infrarenal aortic ischemia reperfusion. Ann Surg 2006 0.82
88 A dual role for lecithin:cholesterol acyltransferase (EC 2.3.1.43) in lipoprotein oxidation. Free Radic Biol Med 2007 0.82
89 The pro-oxidant activity of high-dose vitamin E supplements in vivo. BioDrugs 2006 0.82
90 Folate/homocysteine phenotypes and MTHFR 677C>T genotypes are associated with serum levels of monocyte chemoattractant protein-1. Clin Immunol 2009 0.82
91 Elevated homocysteine is a predictor of all-cause mortality in a prospective cohort of renal transplant recipients. Nephron Clin Pract 2009 0.82
92 Restoration of adipose function in obese glucose-tolerant men following pioglitazone treatment is associated with CCAAT enhancer-binding protein β up-regulation. Clin Sci (Lond) 2012 0.82
93 The vascular and biochemical effects of cilostazol in patients with peripheral arterial disease. J Vasc Surg 2009 0.82
94 A randomised controlled trial of increasing fruit and vegetable intake and how this influences the carotenoid concentration and activities of PON-1 and LCAT in HDL from subjects with type 2 diabetes. Cardiovasc Diabetol 2014 0.81
95 Exercise-induced endotoxemia: the effect of ascorbic acid supplementation. Free Radic Biol Med 2003 0.81
96 Folate and vitamin B12: friendly or enemy nutrients for the elderly. Proc Nutr Soc 2007 0.81
97 Protective effects of ascorbic acid on arterial hemodynamics during acute hyperglycemia. Am J Physiol Heart Circ Physiol 2004 0.81
98 Methylprednisolone favourably alters plasma and urinary cytokine homeostasis and subclinical renal injury at cardiac surgery. Cytokine 2004 0.80
99 Cell salvage alters the systemic inflammatory response after off-pump coronary artery bypass grafting surgery. Ann Thorac Surg 2007 0.80
100 Mitochondrial J haplogroup is associated with lower blood pressure and anti-oxidant status: findings in octo/nonagenarians from the BELFAST Study. Age (Dordr) 2012 0.79
101 The association between glucose-lowering drug use and mortality among breast cancer patients with type 2 diabetes. Breast Cancer Res Treat 2015 0.79
102 Exercise-induced oxidative-nitrosative stress is associated with impaired dynamic cerebral autoregulation and blood-brain barrier leakage. Exp Physiol 2011 0.79
103 Short-term phytoestrogen supplementation alters insulin-like growth factor profile but not lipid or antioxidant status. J Nutr Biochem 2005 0.79
104 Surveillance strategies according to the rate of growth of small abdominal aortic aneurysms. Vasc Med 2011 0.79
105 Elevated soluble cellular adhesion molecules are associated with increased mortality in a prospective cohort of renal transplant recipients. BMC Nephrol 2011 0.78
106 Association between the NAT1 1095C > A polymorphism and homocysteine concentration. Am J Med Genet A 2006 0.78
107 The effects of cilostazol on peripheral neuropathy in diabetic patients with peripheral arterial disease. Angiology 2008 0.78
108 Comparison of 5% versus 15% sucrose intakes as part of a eucaloric diet in overweight and obese subjects: effects on insulin sensitivity, glucose metabolism, vascular compliance, body composition and lipid profile. A randomised controlled trial. Metabolism 2013 0.78
109 Lipid metabolism. Curr Opin Lipidol 2010 0.78
110 Critical difference applied to exercise-induced oxidative stress: the dilemma of distinguishing biological from statistical change. J Physiol Biochem 2012 0.78
111 The assessment of vascular function during dietary intervention trials in human subjects. Br J Nutr 2011 0.78
112 A reduced abbreviated indirect calorimetry protocol is clinically acceptable for use in spontaneously breathing patients with traumatic brain injury. Nutr Clin Pract 2009 0.78
113 Rapid isolation of VLDL subfractions: assessment of composition and susceptibility to copper-mediated oxidation. J Lipid Res 2002 0.78
114 High-density lipoprotein subfractions display proatherogenic properties in overweight and obese children. Pediatr Res 2013 0.78
115 Effect of fruit and vegetable intake on oxidative stress and inflammation in COPD: a randomised controlled trial. Eur Respir J 2011 0.78
116 Progress towards standardization: an IFCC Scientific Division Perspective. Clin Chem Lab Med 2013 0.78
117 A posteriori-derived dietary patterns and retinal vessel caliber in an elderly population. Invest Ophthalmol Vis Sci 2013 0.78
118 Effect of supplementation with B vitamins and antioxidants on levels of asymmetric dimethylarginine (ADMA) and C-reactive protein (CRP): a double-blind, randomised, factorial design, placebo-controlled trial. Eur J Nutr 2010 0.78
119 The two faces of α- and γ-tocopherols: an in vitro and ex vivo investigation into VLDL, LDL and HDL oxidation. J Nutr Biochem 2011 0.78
120 The vascular and biochemical effects of cilostazol in diabetic patients with peripheral arterial disease. Vasc Endovascular Surg 2009 0.78
121 Session 4: CVD, diabetes and cancer: Evidence for the use of the Mediterranean diet in patients with CHD. Proc Nutr Soc 2009 0.77
122 Association between breast-feeding and anthropometry and CVD risk factor status in adolescence and young adulthood: the Young Hearts Project, Northern Ireland. Public Health Nutr 2009 0.77
123 The effect of lutein- and zeaxanthin-rich foods v. supplements on macular pigment level and serological markers of endothelial activation, inflammation and oxidation: pilot studies in healthy volunteers. Br J Nutr 2012 0.77
124 Symptoms of infection and acute mountain sickness; associated metabolic sequelae and problems in differential diagnosis. High Alt Med Biol 2003 0.77
125 Effects of antioxidants on endothelial function in human saphenous vein in an ex vivo model. Angiology 2008 0.77
126 Manipulation of systemic oxygen flux by acute exercise and normobaric hypoxia: implications for reactive oxygen species generation. Clin Sci (Lond) 2006 0.77
127 Oxidative stress and vascular disease: insights from isoprostane measurement. Clin Chem 2005 0.76
128 The relationship between microvascular endothelial function and carotid-radial pulse wave velocity in patients with mild hypertension. Clin Exp Hypertens 2010 0.76
129 The influence of COX-2 single nucleotide polymorphisms on abdominal aortic aneurysm development and the associated inflammation. Angiology 2009 0.76
130 Susceptibility of low-density lipoprotein to oxidation and circulating cell adhesion molecules in young healthy adult offspring of parents with type 2 diabetes. Metabolism 2004 0.76
131 A randomized clinical trial of ascorbic acid in open abdominal aortic aneurysm repair. Intensive Care Med Exp 2015 0.75
132 A few thoughts on reflective testing. Ann Clin Biochem 2006 0.75
133 Lycopene status is not associated with insulin-like growth factor-1 concentration in a healthy male population. Int J Vitam Nutr Res 2007 0.75
134 A clinical, renal and immunological assessment of surface modifying additive treated (SMART) cardiopulmonary bypass circuits. Perfusion 2005 0.75
135 The LDLR variant T705I does not cause the typical phenotype of familial hypercholesterolaemia. Atherosclerosis 2006 0.75
136 Dietary patterns and cardiovascular risk factors in adolescents and young adults: the Northern Ireland Young Hearts Project - CORRIGENDUM. Br J Nutr 2016 0.75
137 Lipid metabolism. Curr Opin Lipidol 2012 0.75
138 Dietary patterns and smoking in Northern Irish men: a population at high risk of coronary heart disease. Int J Vitam Nutr Res 2011 0.75
139 Lipid metabolism. Curr Opin Lipidol 2005 0.75
140 Lipid metabolism. Curr Opin Lipidol 2007 0.75
141 Retroperitoneal approach to abdominal aortic aneurysm repair preserves splanchnic perfusion as measured by gastric tonometry. Ann Vasc Surg 2009 0.75
142 Thiol and cardiovascular risk factor status in a male northern Irish population. Int J Vitam Nutr Res 2009 0.75
143 Synthetic approaches to a chiral 4-amino-3-hydroxy piperidine with pharmaceutical relevance. Org Biomol Chem 2012 0.75
144 Lipid metabolism. Curr Opin Lipidol 2006 0.75
145 Lipid metabolism. Curr Opin Lipidol 2004 0.75
146 Decreased antioxidant vitamin concentration may be a risk factor for recurrent carotid stenosis. Vasc Endovascular Surg 2007 0.75
147 Decreased serum retinol is associated with increased mortality in renal transplant recipients. Clin Chem 2007 0.75
148 Lipid metabolism. Curr Opin Lipidol 2002 0.75
149 α-Tocopherol induces proatherogenic changes to HDL2 & HDL3: an in vitro and ex vivo investigation. Atherosclerosis 2012 0.75
150 IDENTIFYING FEATURES OF EARLY AND LATE AGE-RELATED MACULAR DEGENERATION: A Comparison of Multicolor Versus Traditional Color Fundus Photography. Retina 2017 0.75
151 IFCC Scientific Division. Clin Chem Lab Med 2010 0.75
152 Folate: in vitro and in vivo effects on VLDL and LDL oxidation. Int J Vitam Nutr Res 2007 0.75
153 How well are we training the next generation of clinical pathologists and clinical laboratory directors? A global perspective. Clin Chem 2011 0.75
154 Lipid metabolism. Curr Opin Lipidol 2010 0.75
155 Pioglitazone protects HDL(2&3) against oxidation in overweight and obese men. Ann Clin Biochem 2012 0.75
156 Lipid metabolism. Curr Opin Lipidol 2009 0.75
157 Lipid metabolism. Curr Opin Lipidol 2003 0.75
158 A curvilinear approach to the kinetic analysis of linoleate peroxidation in aqueous liposomes by 2,2'azobis(2-amidoinopropane) dihydrochloride. Chem Phys Lipids 2012 0.75