Published in Adv Cancer Res on January 01, 2007
Nonlinear modelling of cancer: bridging the gap between cells and tumours. Nonlinearity (2010) 2.08
The upstream components of the Wnt signalling pathway in the dynamic EMT and MET associated with colorectal cancer progression. Clin Exp Metastasis (2008) 1.65
Extracellular matrix control of mammary gland morphogenesis and tumorigenesis: insights from imaging. Histochem Cell Biol (2008) 1.55
Three-dimensional multispecies nonlinear tumor growth-II: Tumor invasion and angiogenesis. J Theor Biol (2010) 1.37
Gene expression in histologically normal epithelium from breast cancer patients and from cancer-free prophylactic mastectomy patients shares a similar profile. Br J Cancer (2010) 1.29
MEK4 function, genistein treatment, and invasion of human prostate cancer cells. J Natl Cancer Inst (2009) 1.20
Depletion of nuclear actin is a key mediator of quiescence in epithelial cells. J Cell Sci (2011) 1.16
Genome-wide gene expression analysis in cancer cells reveals 3D growth to affect ECM and processes associated with cell adhesion but not DNA repair. PLoS One (2012) 1.10
Elevated matrix metalloproteinases and collagen fragmentation in photodamaged human skin: impact of altered extracellular matrix microenvironment on dermal fibroblast function. J Invest Dermatol (2013) 1.06
Prolyl-4-hydroxylase α subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition. BMC Cancer (2014) 1.01
Extracellular matrix protein CCN1 limits oncolytic efficacy in glioma. Cancer Res (2012) 1.01
Gene expression in the third dimension: the ECM-nucleus connection. J Mammary Gland Biol Neoplasia (2010) 0.99
Tamoxifen induces pleiotrophic changes in mammary stroma resulting in extracellular matrix that suppresses transformed phenotypes. Breast Cancer Res (2009) 0.99
Isotropic 3D nuclear morphometry of normal, fibrocystic and malignant breast epithelial cells reveals new structural alterations. PLoS One (2012) 0.97
Genetic polymorphisms at TIMP3 are associated with survival of adenocarcinoma of the gastroesophageal junction. PLoS One (2013) 0.86
Breast cancer genomes--form and function. Curr Opin Genet Dev (2010) 0.85
Alterations of Dermal Connective Tissue Collagen in Diabetes: Molecular Basis of Aged-Appearing Skin. PLoS One (2016) 0.79
The RhoA-Rok-myosin II pathway is involved in extracellular matrix-mediated regulation of prolactin signaling in mammary epithelial cells. J Cell Physiol (2012) 0.79
Architecture Is the Message: The role of extracellular matrix and 3-D structure in tissue-specific gene expression and breast cancer. Pezcoller Found J (2007) 0.77
For whom the cells pull: Hydrogel and micropost devices for measuring traction forces. Methods (2015) 0.77
A shift in paradigm towards human biology-based systems for cholestatic-liver diseases. J Physiol (2015) 0.76
The elastin peptide (VGVAPG)3 induces the 3D reorganisation of PML-NBs and SC35 speckles architecture, and accelerates proliferation of fibroblasts and melanoma cells. Histochem Cell Biol (2014) 0.75
Prostate cancer cells specifically reorganize epithelial cell-fibroblast communication through proteoglycan and junction pathways. Cell Adh Migr (2016) 0.75
Loss of Interneuron-Derived Collagen XIX Leads to a Reduction in Perineuronal Nets in the Mammalian Telencephalon. ASN Neuro (2017) 0.75
Cytoplasmic poly (A) binding protein (PABPC2) critically regulates epidermal maintenance and turnover in planarian Schmidtea mediterranea. Development (2017) 0.75
Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. J Cell Biol (1997) 10.61
Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells. Proc Natl Acad Sci U S A (1992) 8.69
Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure. Proc Natl Acad Sci U S A (1997) 7.24
Nuclear speckles: a model for nuclear organelles. Nat Rev Mol Cell Biol (2003) 6.98
Basement membranes: structure, assembly and role in tumour angiogenesis. Nat Rev Cancer (2003) 6.65
Integrin signalling during tumour progression. Nat Rev Mol Cell Biol (2004) 6.53
Coupling of the nucleus and cytoplasm: role of the LINC complex. J Cell Biol (2005) 6.47
Specific inhibition of nuclear RNA polymerase II by alpha-amanitin. Science (1970) 6.39
How does the extracellular matrix direct gene expression? J Theor Biol (1982) 6.38
STATs: signal transducers and activators of transcription. Cell (1996) 6.10
Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane. Development (1989) 5.62
Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: a different perspective in epithelial biology. Proc Natl Acad Sci U S A (1998) 5.34
The dynamics of a pre-mRNA splicing factor in living cells. Nature (1997) 4.97
Control of mammary epithelial differentiation: basement membrane induces tissue-specific gene expression in the absence of cell-cell interaction and morphological polarity. J Cell Biol (1991) 4.91
Global nature of dynamic protein-chromatin interactions in vivo: three-dimensional genome scanning and dynamic interaction networks of chromatin proteins. Mol Cell Biol (2004) 4.41
Regulation of matrix biology by matrix metalloproteinases. Curr Opin Cell Biol (2004) 4.16
Modeling tissue-specific signaling and organ function in three dimensions. J Cell Sci (2003) 3.52
Epithelial cytoskeletal framework and nuclear matrix-intermediate filament scaffold: three-dimensional organization and protein composition. J Cell Biol (1984) 3.48
Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription. EMBO J (1994) 3.32
Interaction of mouse mammary epithelial cells with collagen substrata: regulation of casein gene expression and secretion. Proc Natl Acad Sci U S A (1985) 3.23
Form follows function: The genomic organization of cellular differentiation. Genes Dev (2004) 3.20
Microenvironmental regulators of tissue structure and function also regulate tumor induction and progression: the role of extracellular matrix and its degrading enzymes. Cold Spring Harb Symp Quant Biol (2005) 3.19
Nesprin-3, a novel outer nuclear membrane protein, associates with the cytoskeletal linker protein plectin. J Cell Biol (2005) 3.17
Multi-faceted regulation of cell differentiation by extracellular matrix. FASEB J (1993) 3.14
The cytoskeleton and cell signaling: component localization and mechanical coupling. Physiol Rev (1998) 3.13
Chromatin remodelling in mammalian differentiation: lessons from ATP-dependent remodellers. Nat Rev Genet (2006) 3.12
Integrin signaling to the actin cytoskeleton. Curr Opin Cell Biol (2003) 3.11
RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivo. Mol Cell (1999) 3.10
Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction. Proc Natl Acad Sci U S A (1994) 3.09
Polarity and proliferation are controlled by distinct signaling pathways downstream of PI3-kinase in breast epithelial tumor cells. J Cell Biol (2004) 2.93
Visualization of gene activity in living cells. Nat Cell Biol (2000) 2.88
Tissue structure, nuclear organization, and gene expression in normal and malignant breast. Cancer Res (1999) 2.84
Laminin mediates tissue-specific gene expression in mammary epithelia. J Cell Biol (1995) 2.83
A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle. Cell (1993) 2.80
Pondering the promyelocytic leukemia protein (PML) puzzle: possible functions for PML nuclear bodies. Mol Cell Biol (2002) 2.57
In vivo analysis of the stability and transport of nuclear poly(A)+ RNA. J Cell Biol (1994) 2.52
A hierarchy of ECM-mediated signalling regulates tissue-specific gene expression. Curr Opin Cell Biol (1995) 2.33
Tissue phenotype depends on reciprocal interactions between the extracellular matrix and the structural organization of the nucleus. Proc Natl Acad Sci U S A (1998) 2.32
Rapid periodic binding and displacement of the glucocorticoid receptor during chromatin remodeling. Mol Cell (2004) 2.25
Concepts in nuclear architecture. Bioessays (2005) 2.19
Tyrosine phosphorylation of mammalian RNA polymerase II carboxyl-terminal domain. Proc Natl Acad Sci U S A (1993) 2.17
A novel transcriptional enhancer is involved in the prolactin- and extracellular matrix-dependent regulation of beta-casein gene expression. Mol Biol Cell (1992) 2.15
The extracellular matrix coordinately modulates liver transcription factors and hepatocyte morphology. Mol Cell Biol (1991) 2.11
Promyelocytic leukemia (PML) nuclear bodies are protein structures that do not accumulate RNA. J Cell Biol (2000) 2.11
Subnuclear organelles: new insights into form and function. Trends Cell Biol (2005) 2.10
Extracellular matrix regulates expression of the TGF-beta 1 gene. J Cell Biol (1993) 1.84
A novel regulatory mechanism for whey acidic protein gene expression. Cell Regul (1989) 1.82
Progesterone and glucocorticoid receptors recruit distinct coactivator complexes and promote distinct patterns of local chromatin modification. Mol Cell Biol (2003) 1.73
Gene expression signature in organized and growth-arrested mammary acini predicts good outcome in breast cancer. Cancer Res (2006) 1.69
Identification of a nuclear domain with deacetylase activity. Proc Natl Acad Sci U S A (2000) 1.64
p300/CREB-binding protein enhances the prolactin-mediated transcriptional induction through direct interaction with the transactivation domain of Stat5, but does not participate in the Stat5-mediated suppression of the glucocorticoid response. Mol Endocrinol (1998) 1.62
Nuclear organization of pre-mRNA processing. Curr Opin Cell Biol (1993) 1.62
Disruption of 3D tissue integrity facilitates adenovirus infection by deregulating the coxsackievirus and adenovirus receptor. Proc Natl Acad Sci U S A (2003) 1.61
Regulation of milk protein gene expression. Annu Rev Nutr (1999) 1.55
Characterization of BCE-1, a transcriptional enhancer regulated by prolactin and extracellular matrix and modulated by the state of histone acetylation. Mol Cell Biol (1998) 1.52
Reconstitution of glucocorticoid receptor-dependent transcription in vivo. Mol Cell Biol (2004) 1.45
Nuclear bodies and compartments: functional roles and cellular signalling in health and disease. Cell Signal (2004) 1.41
The role of the nuclear envelope in cellular organization. Cell Mol Life Sci (2006) 1.32
AZU-1: a candidate breast tumor suppressor and biomarker for tumor progression. Mol Biol Cell (2000) 1.30
DNA methylation control of tissue polarity and cellular differentiation in the mammary epithelium. Exp Cell Res (2004) 1.23
Dynamics of nuclear receptor movement and transcription. Biochim Biophys Acta (2004) 1.20
PML interaction with p53 and its role in apoptosis and replicative senescence. Oncogene (2001) 1.19
Abrogation of retinoblastoma protein function by c-Abl through tyrosine kinase-dependent and -independent mechanisms. Mol Cell Biol (1995) 1.19
Higher-order nuclear organization in growth arrest of human mammary epithelial cells: a novel role for telomere-associated protein TIN2. J Cell Sci (2005) 1.17
Nuclear structure and the three-dimensional organization of DNA. J Cell Biochem (1991) 1.16
Chromatin organization measured by AluI restriction enzyme changes with malignancy and is regulated by the extracellular matrix and the cytoskeleton. Am J Pathol (2005) 1.14
Extracellular matrix regulates whey acidic protein gene expression by suppression of TGF-alpha in mouse mammary epithelial cells: studies in culture and in transgenic mice. J Cell Biol (1995) 1.13
Automated local bright feature image analysis of nuclear protein distribution identifies changes in tissue phenotype. Proc Natl Acad Sci U S A (2006) 1.13
Identification of a binding site in c-Ab1 tyrosine kinase for the C-terminal repeated domain of RNA polymerase II. Mol Cell Biol (1996) 1.13
Regulation of mammary differentiation by extracellular matrix involves protein-tyrosine phosphatases. J Biol Chem (1998) 1.07
A role for the cytoskeleton in prolactin-dependent mammary epithelial cell differentiation. J Cell Sci (2004) 1.06
A conserved organization of transcription during embryonic stem cell differentiation and in cells with high C value. Mol Biol Cell (2006) 1.06
Prolactin-mediated gene activation in mammary epithelial cells. Curr Opin Genet Dev (1995) 1.05
Trichostatin A inhibits beta-casein expression in mammary epithelial cells. J Cell Biochem (2001) 1.04
Epithelial structure revealed by chemical dissection and unembedded electron microscopy. J Cell Biol (1984) 1.01
The nuclear matrix and the regulation of chromatin organization and function. Int Rev Cytol (1995) 0.99
Rearrangement of nuclear ribonucleoprotein (RNP)-containing structures during apoptosis and transcriptional arrest. Biol Cell (2004) 0.97
NCoA-1/SRC-1 is an essential coactivator of STAT5 that binds to the FDL motif in the alpha-helical region of the STAT5 transactivation domain. J Biol Chem (2003) 0.97
Integrin signaling and mammary cell function. J Mammary Gland Biol Neoplasia (2003) 0.95
STAT5B-mediated growth hormone signaling is organized by highly dynamic microtubules in hepatic cells. J Biol Chem (2004) 0.93
Transcriptional activation by viral enhancers: critical dependence on extracellular matrix-cell interactions in mammary epithelial cells. Mol Carcinog (1994) 0.90
Malignant mammary cells acquire independence from extracellular context for regulation of estrogen receptor alpha. Clin Cancer Res (2004) 0.88
Dystroglycan: emerging roles in mammary gland function. J Mammary Gland Biol Neoplasia (2003) 0.87
Lactoferrin expression in mammary epithelial cells is mediated by changes in cell shape and actin cytoskeleton. J Cell Sci (1997) 0.86
Age-dependent remodeling of connective tissue: role of fibronectin and laminin. Pathol Biol (Paris) (2003) 0.84
An extracellular matrix response element in the promoter of the LpS1 genes of the sea urchin Lytechinus pictus. Nucleic Acids Res (1997) 0.79
Extracellular matrix regulates alpha s1-casein gene expression in rabbit primary mammary cells and CCAAT enhancer binding protein (C/EBP) binding activity. J Cell Biochem (2001) 0.78
Three-dimensional culture models of normal and malignant breast epithelial cells. Nat Methods (2007) 7.43
Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability. Nature (2005) 7.24
Of extracellular matrix, scaffolds, and signaling: tissue architecture regulates development, homeostasis, and cancer. Annu Rev Cell Dev Biol (2006) 6.64
Isolation, immortalization, and characterization of a human breast epithelial cell line with stem cell properties. Genes Dev (2002) 6.55
The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression. Mol Oncol (2007) 5.81
beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium. Cancer Cell (2002) 5.56
Regulation of in situ to invasive breast carcinoma transition. Cancer Cell (2008) 4.46
Normal and tumor-derived myoepithelial cells differ in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition. J Cell Sci (2002) 4.25
Tissue geometry determines sites of mammary branching morphogenesis in organotypic cultures. Science (2006) 4.12
Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway. Cell (2012) 4.09
Evidence for a stem cell hierarchy in the adult human breast. J Cell Biol (2007) 3.76
Modeling tissue-specific signaling and organ function in three dimensions. J Cell Sci (2003) 3.52
Phenotypic reversion or death of cancer cells by altering signaling pathways in three-dimensional contexts. J Natl Cancer Inst (2002) 3.39
The perivascular niche regulates breast tumour dormancy. Nat Cell Biol (2013) 3.36
Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition. Cancer Res (2009) 3.14
Regulation of mammary gland branching morphogenesis by the extracellular matrix and its remodeling enzymes. Breast Cancer Res (2003) 3.13
Tumor reversion: correction of malignant behavior by microenvironmental cues. Int J Cancer (2003) 3.02
Polarity and proliferation are controlled by distinct signaling pathways downstream of PI3-kinase in breast epithelial tumor cells. J Cell Biol (2004) 2.93
Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo. Cancer Res (2006) 2.86
Site-specific inductive and inhibitory activities of MMP-2 and MMP-3 orchestrate mammary gland branching morphogenesis. J Cell Biol (2003) 2.68
Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance. Cancer Cell (2012) 2.61
MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrin subunits. Nat Cell Biol (2012) 2.61
Modeling dynamic reciprocity: engineering three-dimensional culture models of breast architecture, function, and neoplastic transformation. Semin Cancer Biol (2005) 2.53
Unraveling the microenvironmental influences on the normal mammary gland and breast cancer. Semin Cancer Biol (2008) 2.41
Mechanism of Akt1 inhibition of breast cancer cell invasion reveals a protumorigenic role for TSC2. Proc Natl Acad Sci U S A (2006) 2.41
HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment. Breast Cancer Res Treat (2009) 2.34
Fibrosis and cancer: do myofibroblasts come also from epithelial cells via EMT? J Cell Biochem (2007) 2.32
Targeting TACE-dependent EGFR ligand shedding in breast cancer. J Clin Invest (2007) 2.29
Mechanisms of disease: epithelial-mesenchymal transition--does cellular plasticity fuel neoplastic progression? Nat Clin Pract Oncol (2008) 2.18
Prognostic breast cancer signature identified from 3D culture model accurately predicts clinical outcome across independent datasets. PLoS One (2008) 2.12
Epithelial to mesenchymal transition in human breast cancer can provide a nonmalignant stroma. Am J Pathol (2003) 2.06
The MAPK(ERK-1,2) pathway integrates distinct and antagonistic signals from TGFalpha and FGF7 in morphogenesis of mouse mammary epithelium. Dev Biol (2007) 1.98
Tissue architecture and function: dynamic reciprocity via extra- and intra-cellular matrices. Cancer Metastasis Rev (2009) 1.93
Myoepithelial cells: their origin and function in breast morphogenesis and neoplasia. J Mammary Gland Biol Neoplasia (2005) 1.92
Beta1 integrin inhibition dramatically enhances radiotherapy efficacy in human breast cancer xenografts. Cancer Res (2008) 1.83
Human mammary progenitor cell fate decisions are products of interactions with combinatorial microenvironments. Integr Biol (Camb) (2008) 1.82
The hyaluronan receptors CD44 and Rhamm (CD168) form complexes with ERK1,2 that sustain high basal motility in breast cancer cells. J Biol Chem (2007) 1.82
A microRNA regulatory mechanism of osteoblast differentiation. Proc Natl Acad Sci U S A (2009) 1.80
A human breast cell model of preinvasive to invasive transition. Cancer Res (2008) 1.79
The tumor microenvironment is a dominant force in multidrug resistance. Drug Resist Updat (2012) 1.77
Laminin and biomimetic extracellular elasticity enhance functional differentiation in mammary epithelia. EMBO J (2008) 1.74
The dominance of the microenvironment in breast and ovarian cancer. Semin Cancer Biol (2002) 1.73
Targeting the tumor microenvironment. Front Biosci (2007) 1.72
Gene expression signature in organized and growth-arrested mammary acini predicts good outcome in breast cancer. Cancer Res (2006) 1.69
Myoepithelial cells: good fences make good neighbors. Breast Cancer Res (2005) 1.66
A role for dystroglycan in epithelial polarization: loss of function in breast tumor cells. Cancer Res (2002) 1.65
Cell shape regulates global histone acetylation in human mammary epithelial cells. Exp Cell Res (2007) 1.64
Cancer. Respect thy neighbor! Science (2004) 1.62
Ionizing radiation predisposes nonmalignant human mammary epithelial cells to undergo transforming growth factor beta induced epithelial to mesenchymal transition. Cancer Res (2007) 1.60
Breast cancer by proxy: can the microenvironment be both the cause and consequence? Trends Mol Med (2008) 1.60
Evidence for formation of DNA repair centers and dose-response nonlinearity in human cells. Proc Natl Acad Sci U S A (2011) 1.58
β1 integrin mediates an alternative survival pathway in breast cancer cells resistant to lapatinib. Breast Cancer Res (2011) 1.56
Extracellular matrix control of mammary gland morphogenesis and tumorigenesis: insights from imaging. Histochem Cell Biol (2008) 1.55
Sema3A regulates bone-mass accrual through sensory innervations. Nature (2013) 1.53
Dystroglycan loss disrupts polarity and beta-casein induction in mammary epithelial cells by perturbing laminin anchoring. J Cell Sci (2006) 1.49
Molecular predictors of 3D morphogenesis by breast cancer cell lines in 3D culture. PLoS Comput Biol (2010) 1.46
Extracellular matrix-regulated gene expression requires cooperation of SWI/SNF and transcription factors. J Biol Chem (2007) 1.46
Coherent angular motion in the establishment of multicellular architecture of glandular tissues. Proc Natl Acad Sci U S A (2012) 1.45
Cytokeratin-18 is a useful serum biomarker for early determination of response of breast carcinomas to chemotherapy. Clin Cancer Res (2007) 1.45
Sustained activation of STAT5 is essential for chromatin remodeling and maintenance of mammary-specific function. J Cell Biol (2009) 1.44
Change in cell shape is required for matrix metalloproteinase-induced epithelial-mesenchymal transition of mammary epithelial cells. J Cell Biochem (2008) 1.41
Self-organization of engineered epithelial tubules by differential cellular motility. Proc Natl Acad Sci U S A (2009) 1.36
Splicing program of human MENA produces a previously undescribed isoform associated with invasive, mesenchymal-like breast tumors. Proc Natl Acad Sci U S A (2012) 1.36
Three-dimensional lithographically defined organotypic tissue arrays for quantitative analysis of morphogenesis and neoplastic progression. Nat Protoc (2008) 1.35
Proteolytic enzymes and altered glycosylation modulate dystroglycan function in carcinoma cells. Cancer Res (2004) 1.33
Is CD133 a marker of metastatic colon cancer stem cells? J Clin Invest (2008) 1.32
Breast cancer cells in three-dimensional culture display an enhanced radioresponse after coordinate targeting of integrin alpha5beta1 and fibronectin. Cancer Res (2010) 1.32
Rhamm-/- fibroblasts are defective in CD44-mediated ERK1,2 motogenic signaling, leading to defective skin wound repair. J Cell Biol (2006) 1.28
Collagen-IV and laminin-1 regulate estrogen receptor alpha expression and function in mouse mammary epithelial cells. J Cell Sci (2003) 1.27
Three-dimensional culture of human breast epithelial cells: the how and the why. Methods Mol Biol (2013) 1.26
Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin β1. Development (2013) 1.23
Rap1 integrates tissue polarity, lumen formation, and tumorigenic potential in human breast epithelial cells. Cancer Res (2007) 1.22
Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity. Proc Natl Acad Sci U S A (2012) 1.21
Epithelial-mesenchymal transition: general principles and pathological relevance with special emphasis on the role of matrix metalloproteinases. Cold Spring Harb Perspect Biol (2012) 1.20
Dissecting regional variations in stress fiber mechanics in living cells with laser nanosurgery. Biophys J (2010) 1.20
To create the correct microenvironment: three-dimensional heterotypic collagen assays for human breast epithelial morphogenesis and neoplasia. Methods (2003) 1.19
p53-dependent integration of telomere and growth factor deprivation signals. Proc Natl Acad Sci U S A (2007) 1.18
Delivering the message: epimorphin and mammary epithelial morphogenesis. Trends Cell Biol (2003) 1.18
The organization of tight junctions in epithelia: implications for mammary gland biology and breast tumorigenesis. J Mammary Gland Biol Neoplasia (2003) 1.18
Higher-order nuclear organization in growth arrest of human mammary epithelial cells: a novel role for telomere-associated protein TIN2. J Cell Sci (2005) 1.17
Depletion of nuclear actin is a key mediator of quiescence in epithelial cells. J Cell Sci (2011) 1.16
Order and disorder: the role of extracellular matrix in epithelial cancer. Cancer Invest (2002) 1.15
Epithelial progenitor cell lines as models of normal breast morphogenesis and neoplasia. Cell Prolif (2003) 1.15
Raf-induced MMP9 disrupts tissue architecture of human breast cells in three-dimensional culture and is necessary for tumor growth in vivo. Genes Dev (2010) 1.14
The tumor microenvironment modulates tamoxifen resistance in breast cancer: a role for soluble stromal factors and fibronectin through β1 integrin. Breast Cancer Res Treat (2011) 1.14
Chromatin organization measured by AluI restriction enzyme changes with malignancy and is regulated by the extracellular matrix and the cytoskeleton. Am J Pathol (2005) 1.14
Cytoplasmic SnoN in normal tissues and nonmalignant cells antagonizes TGF-beta signaling by sequestration of the Smad proteins. Proc Natl Acad Sci U S A (2005) 1.14
Of microenvironments and mammary stem cells. Stem Cell Rev (2007) 1.14
Automated local bright feature image analysis of nuclear protein distribution identifies changes in tissue phenotype. Proc Natl Acad Sci U S A (2006) 1.13
Tumor engineering: the other face of tissue engineering. Tissue Eng Part A (2010) 1.12
Single proteins might have dual but related functions in intracellular and extracellular microenvironments. Nat Rev Mol Cell Biol (2009) 1.12
Increased sugar uptake promotes oncogenesis via EPAC/RAP1 and O-GlcNAc pathways. J Clin Invest (2013) 1.11
Self-organization is a dynamic and lineage-intrinsic property of mammary epithelial cells. Proc Natl Acad Sci U S A (2011) 1.11
A closed-loop brain-computer interface triggering an active ankle-foot orthosis for inducing cortical neural plasticity. IEEE Trans Biomed Eng (2014) 1.11
IL-25 causes apoptosis of IL-25R-expressing breast cancer cells without toxicity to nonmalignant cells. Sci Transl Med (2011) 1.11