Published in BMC Plant Biol on April 11, 2007
SIFT web server: predicting effects of amino acid substitutions on proteins. Nucleic Acids Res (2012) 4.45
A modified TILLING approach to detect induced mutations in tetraploid and hexaploid wheat. BMC Plant Biol (2009) 2.57
The million mutation project: a new approach to genetics in Caenorhabditis elegans. Genome Res (2013) 2.20
TILLING to detect induced mutations in soybean. BMC Plant Biol (2008) 2.13
Development and characterization of an oat TILLING-population and identification of mutations in lignin and beta-glucan biosynthesis genes. BMC Plant Biol (2010) 1.82
Reverse genetics in zebrafish by TILLING. Brief Funct Genomic Proteomic (2008) 1.73
MNU-induced mutant pools and high performance TILLING enable finding of any gene mutation in rice. Mol Genet Genomics (2007) 1.69
Applying genotyping (TILLING) and phenotyping analyses to elucidate gene function in a chemically induced sorghum mutant population. BMC Plant Biol (2008) 1.57
UTILLdb, a Pisum sativum in silico forward and reverse genetics tool. Genome Biol (2008) 1.56
Harvesting the promising fruits of genomics: applying genome sequencing technologies to crop breeding. PLoS Biol (2014) 1.42
Engineering melon plants with improved fruit shelf life using the TILLING approach. PLoS One (2010) 1.37
Implementation of two high through-put techniques in a novel application: detecting point mutations in large EMS mutated plant populations. Plant Methods (2009) 1.34
Discovery of rare mutations in populations: TILLING by sequencing. Plant Physiol (2011) 1.32
A new mutant genetic resource for tomato crop improvement by TILLING technology. BMC Res Notes (2010) 1.29
Mutant resources in rice for functional genomics of the grasses. Plant Physiol (2009) 1.25
Efficient Genome-Wide Detection and Cataloging of EMS-Induced Mutations Using Exome Capture and Next-Generation Sequencing. Plant Cell (2014) 1.21
Systems approaches to identifying gene regulatory networks in plants. Annu Rev Cell Dev Biol (2008) 1.21
TILLING: a shortcut in functional genomics. J Appl Genet (2011) 1.16
Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animals. BMC Genomics (2008) 1.14
Retention of induced mutations in a Drosophila reverse-genetic resource. Genetics (2008) 1.14
TILLING in Lotus japonicus identified large allelic series for symbiosis genes and revealed a bias in functionally defective ethyl methanesulfonate alleles toward glycine replacements. Plant Physiol (2009) 1.09
Characterization of highly efficient heavy-ion mutagenesis in Arabidopsis thaliana. BMC Plant Biol (2011) 1.07
Reference genome-independent assessment of mutation density using restriction enzyme-phased sequencing. BMC Genomics (2012) 1.05
Development and characterization of a new TILLING population of common bread wheat (Triticum aestivum L.). PLoS One (2012) 1.04
A diploid wheat TILLING resource for wheat functional genomics. BMC Plant Biol (2012) 1.02
Towards a TILLING platform for functional genomics in Piel de Sapo melons. BMC Res Notes (2011) 1.02
Assessment of FAE1 polymorphisms in three Brassica species using EcoTILLING and their association with differences in seed erucic acid contents. BMC Plant Biol (2010) 1.00
A high-density collection of EMS-induced mutations for TILLING in Landsberg erecta genetic background of Arabidopsis. BMC Plant Biol (2009) 1.00
A TILLING Platform for Functional Genomics in Brachypodium distachyon. PLoS One (2013) 1.00
TILLING for allergen reduction and improvement of quality traits in peanut (Arachis hypogaea L.). BMC Plant Biol (2011) 0.99
A nonsense mutation in a putative sulphate transporter gene results in low phytic acid in barley. Funct Integr Genomics (2011) 0.99
Statistical mutation calling from sequenced overlapping DNA pools in TILLING experiments. BMC Bioinformatics (2011) 0.97
Reduction of phytic acid and enhancement of bioavailable micronutrients in food grains. J Food Sci Technol (2013) 0.96
TILLING in grass species. Plant Physiol (2009) 0.96
High Resolution Melt (HRM) analysis is an efficient tool to genotype EMS mutants in complex crop genomes. Plant Methods (2011) 0.96
Application of TILLING and EcoTILLING as Reverse Genetic Approaches to Elucidate the Function of Genes in Plants and Animals. Curr Genomics (2008) 0.96
iTILLING: a personalized approach to the identification of induced mutations in Arabidopsis. Plant Physiol (2010) 0.93
Attenuation of cocaine-induced locomotor sensitization in rats sustaining genetic or pharmacologic antagonism of ghrelin receptors. Addict Biol (2011) 0.92
Genome-wide survey of artificial mutations induced by ethyl methanesulfonate and gamma rays in tomato. Plant Biotechnol J (2015) 0.89
sunTILL: a TILLING resource for gene function analysis in sunflower. Plant Methods (2011) 0.88
Potential of a mutant-based reverse genetic approach for functional genomics and molecular breeding in soybean. Breed Sci (2012) 0.88
Mutagenesis as a tool in plant genetics, functional genomics, and breeding. Int J Plant Genomics (2012) 0.87
Genetic screening of Fabry patients with EcoTILLING and HRM technology. BMC Res Notes (2011) 0.86
Production of a high-efficiency TILLING population through polyploidization. Plant Physiol (2013) 0.86
Rapid identification and recovery of ENU-induced mutations with next-generation sequencing and Paired-End Low-Error analysis. BMC Genomics (2015) 0.85
High-throughput discovery of mutations in tef semi-dwarfing genes by next-generation sequencing analysis. Genetics (2012) 0.85
Natural and artificial mutants as valuable resources for functional genomics and molecular breeding. Int J Biol Sci (2010) 0.83
PT-Flax (phenotyping and TILLinG of flax): development of a flax (Linum usitatissimum L.) mutant population and TILLinG platform for forward and reverse genetics. BMC Plant Biol (2013) 0.83
Construction of a high-density mutant library in soybean and development of a mutant retrieval method using amplicon sequencing. BMC Genomics (2015) 0.82
Ghrelin and ghrelin receptor modulation of psychostimulant action. Front Neurosci (2013) 0.82
EMS mutagenesis in mature seed-derived rice calli as a new method for rapidly obtaining TILLING mutant populations. Plant Methods (2014) 0.82
Updating the Micro-Tom TILLING platform. Breed Sci (2013) 0.81
Genetic analysis of ion-beam induced extremely late heading mutants in rice. Breed Sci (2014) 0.81
International Consortium of Rice Mutagenesis: resources and beyond. Rice (N Y) (2013) 0.79
Physiological, anatomical and transcriptional alterations in a rice mutant leading to enhanced water stress tolerance. AoB Plants (2015) 0.79
Development of a Cucumis sativus TILLinG platform for forward and reverse genetics. PLoS One (2014) 0.79
Brain reinforcement system function is ghrelin dependent: studies in the rat using pharmacological fMRI and intracranial self-stimulation. Addict Biol (2011) 0.79
Mutations in single FT- and TFL1-paralogs of rapeseed (Brassica napus L.) and their impact on flowering time and yield components. Front Plant Sci (2014) 0.78
Ion Torrent sequencing as a tool for mutation discovery in the flax (Linum usitatissimum L.) genome. Plant Methods (2015) 0.78
Scanning the effects of ethyl methanesulfonate on the whole genome of Lotus japonicus using second-generation sequencing analysis. G3 (Bethesda) (2015) 0.78
DHPLC technology for high-throughput detection of mutations in a durum wheat TILLING population. BMC Genet (2016) 0.78
Induction, rapid fixation and retention of mutations in vegetatively propagated banana. Plant Biotechnol J (2012) 0.78
Discovery of rare mutations in extensively pooled DNA samples using multiple target enrichment. Plant Biotechnol J (2014) 0.77
Genetic architecture of variation in heading date among Asian rice accessions. BMC Plant Biol (2015) 0.77
TILLING by sequencing to identify induced mutations in stress resistance genes of peanut (Arachis hypogaea). BMC Genomics (2015) 0.77
Quantitative trait loci from identification to exploitation for crop improvement. Plant Cell Rep (2017) 0.77
Integrated metabolomics and phytochemical genomics approaches for studies on rice. Gigascience (2016) 0.76
A novel GmFAD3-2a mutant allele developed through TILLING reduces α-linolenic acid content in soybean seed oil. Breed Sci (2014) 0.76
EcoTILLING-Based Association Mapping Efficiently Delineates Functionally Relevant Natural Allelic Variants of Candidate Genes Governing Agronomic Traits in Chickpea. Front Plant Sci (2016) 0.75
Development of EMS-induced mutation population for amylose and resistant starch variation in bread wheat (Triticum aestivum) and identification of candidate genes responsible for amylose variation. BMC Plant Biol (2016) 0.75
Development and utilization of a new chemically-induced soybean library with a high mutation density. J Integr Plant Biol (2016) 0.75
Review of functional markers for improving cooking, eating, and the nutritional qualities of rice. Front Plant Sci (2015) 0.75
Mutagenesis and TILLING to Dissect Gene Function in Plants. Curr Genomics (2016) 0.75
Gene Overexpression Resources in Cereals for Functional Genomics and Discovery of Useful Genes. Front Plant Sci (2016) 0.75
Microspore Induced Doubled Haploids Production from Ethyl Methanesulfonate (EMS) Soaked Flower Buds Is an Efficient Strategy for Mutagenesis in Chinese Cabbage. Front Plant Sci (2016) 0.75
Ascribing Functions to Genes: Journey Towards Genetic Improvement of Rice Via Functional Genomics. Curr Genomics (2016) 0.75
High-Throughput Sequencing Reveals Single Nucleotide Variants in Longer-Kernel Bread Wheat. Front Plant Sci (2016) 0.75
Lotus Base: An integrated information portal for the model legume Lotus japonicus. Sci Rep (2016) 0.75
COTIP: Cotton TILLING Platform, a Resource for Plant Improvement and Reverse Genetic Studies. Front Plant Sci (2016) 0.75
Identification and linkage analysis of a new rice bacterial blight resistance gene from XM14, a mutant line from IR24. Breed Sci (2016) 0.75
Induced Mutagenesis in UGT74S1 Gene Leads to Stable New Flax Lines with Altered Secoisolariciresinol Diglucoside (SDG) Profiles. Front Plant Sci (2017) 0.75
Morphological phenotyping and genetic analyses of a new chemical-mutagenized population of tobacco (Nicotiana tabacum L.). Planta (2017) 0.75
SIFT: Predicting amino acid changes that affect protein function. Nucleic Acids Res (2003) 52.26
A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science (2002) 42.78
Genome-wide insertional mutagenesis of Arabidopsis thaliana. Science (2003) 39.19
The map-based sequence of the rice genome. Nature (2005) 24.17
A draft sequence of the rice genome (Oryza sativa L. ssp. japonica). Science (2002) 21.26
Construct design for efficient, effective and high-throughput gene silencing in plants. Plant J (2001) 7.73
Targeted screening for induced mutations. Nat Biotechnol (2000) 4.89
Large-scale discovery of induced point mutations with high-throughput TILLING. Genome Res (2003) 4.39
Spectrum of chemically induced mutations from a large-scale reverse-genetic screen in Arabidopsis. Genetics (2003) 3.70
Efficient target-selected mutagenesis in zebrafish. Genome Res (2003) 3.61
Single-nucleotide mutations for plant functional genomics. Annu Rev Plant Biol (2003) 3.39
A reverse genetic, nontransgenic approach to wheat crop improvement by TILLING. Nat Biotechnol (2004) 3.03
A structured mutant population for forward and reverse genetics in Barley (Hordeum vulgare L.). Plant J (2004) 2.77
Generation of a flanking sequence-tag database for activation-tagging lines in japonica rice. Plant J (2006) 2.69
Discovery of induced point mutations in maize genes by TILLING. BMC Plant Biol (2004) 2.57
An SNP resource for rice genetics and breeding based on subspecies indica and japonica genome alignments. Genome Res (2004) 2.56
Efficient discovery of DNA polymorphisms in natural populations by Ecotilling. Plant J (2004) 2.45
A TILLING reverse genetics tool and a web-accessible collection of mutants of the legume Lotus japonicus. Plant Physiol (2003) 2.30
Mismatch cleavage by single-strand specific nucleases. Nucleic Acids Res (2004) 2.14
RNA silencing of single and multiple members in a gene family of rice. Plant Physiol (2005) 2.10
Rice mutant resources for gene discovery. Plant Mol Biol (2004) 1.99
TILLING: practical single-nucleotide mutation discovery. Plant J (2006) 1.94
Chemical- and irradiation-induced mutants of indica rice IR64 for forward and reverse genetics. Plant Mol Biol (2005) 1.85
Target-selected mutant screen by TILLING in Drosophila. Genome Res (2005) 1.83
DNA base changes and alkylation following in vivo exposure of Escherichia coli to N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea. Proc Natl Acad Sci U S A (1987) 1.81
Effectiveness of RNA interference in transgenic plants. FEBS Lett (2004) 1.79
A fast neutron deletion mutagenesis-based reverse genetics system for plants. Plant J (2001) 1.79
High-throughput TILLING for functional genomics. Methods Mol Biol (2003) 1.70
PARSESNP: A tool for the analysis of nucleotide polymorphisms. Nucleic Acids Res (2003) 1.63
Automated band mapping in electrophoretic gel images using background information. Nucleic Acids Res (2005) 1.49
A review of the genetic effects of ethyl methanesulfonate. Mutat Res (1985) 1.45
TILLING is an effective reverse genetics technique for Caenorhabditis elegans. BMC Genomics (2006) 1.40
Mutational specificity of ethyl methanesulfonate in excision-repair-proficient and -deficient strains of Drosophila melanogaster. Mol Gen Genet (1991) 1.26
Efficient insertional mutagenesis in rice using the maize En/Spm elements. Plant J (2005) 1.13
Reverse genetic approaches for functional genomics of rice. Plant Mol Biol (2005) 1.07
TILLING without a plough: a new method with applications for reverse genetics. Curr Opin Plant Biol (2005) 1.05
Site preferences of insertional mutagenesis agents in Arabidopsis. Plant Physiol (2004) 0.98
High-throughput TILLING for Arabidopsis. Methods Mol Biol (2006) 0.94
Chemical mutagenesis of the mouse genome: an overview. Genetica (2004) 0.93
Sodium azide mutagenesis: preferential generation of A.T-->G.C transitions in the barley Ant18 gene. Proc Natl Acad Sci U S A (1993) 0.93
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Different mutation frequencies and spectra among organs by N-methyl-N-nitrosourea in rpsL (strA) transgenic mice. Jpn J Cancer Res (2000) 0.84
Quantitative relationship between ethylated DNA bases and gene mutation at two loci in CHO cells. Environ Mol Mutagen (1993) 0.81
SIFT: Predicting amino acid changes that affect protein function. Nucleic Acids Res (2003) 52.26
Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm. Nat Protoc (2009) 38.62
Accounting for human polymorphisms predicted to affect protein function. Genome Res (2002) 14.10
Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science (2010) 12.39
Genome-wide analysis of Arabidopsis thaliana DNA methylation uncovers an interdependence between methylation and transcription. Nat Genet (2006) 11.88
Unlocking the secrets of the genome. Nature (2009) 11.80
Predicting the effects of amino acid substitutions on protein function. Annu Rev Genomics Hum Genet (2006) 9.80
The histone variant H3.3 marks active chromatin by replication-independent nucleosome assembly. Mol Cell (2002) 9.80
Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project. Science (2010) 9.78
The epigenetic progenitor origin of human cancer. Nat Rev Genet (2006) 9.65
Genome-scale profiling of histone H3.3 replacement patterns. Nat Genet (2005) 7.22
Genetic structure and diversity in Oryza sativa L. Genetics (2005) 5.74
Understanding mechanisms of novel gene expression in polyploids. Trends Genet (2003) 4.90
Histone H3.3 is enriched in covalent modifications associated with active chromatin. Proc Natl Acad Sci U S A (2004) 4.88
Genome-wide kinetics of nucleosome turnover determined by metabolic labeling of histones. Science (2010) 4.72
Centromeric nucleosomes induce positive DNA supercoils. Cell (2009) 4.57
DNA demethylation in the Arabidopsis genome. Proc Natl Acad Sci U S A (2007) 4.55
SIFT web server: predicting effects of amino acid substitutions on proteins. Nucleic Acids Res (2012) 4.45
Histone variants--ancient wrap artists of the epigenome. Nat Rev Mol Cell Biol (2010) 4.45
Large-scale discovery of induced point mutations with high-throughput TILLING. Genome Res (2003) 4.39
Histone H2A.Z and DNA methylation are mutually antagonistic chromatin marks. Nature (2008) 4.20
Histone replacement marks the boundaries of cis-regulatory domains. Science (2007) 4.06
Genomewide nonadditive gene regulation in Arabidopsis allotetraploids. Genetics (2005) 3.78
Spectrum of chemically induced mutations from a large-scale reverse-genetic screen in Arabidopsis. Genetics (2003) 3.70
Sequencing of a rice centromere uncovers active genes. Nat Genet (2004) 3.66
CODEHOP (COnsensus-DEgenerate Hybrid Oligonucleotide Primer) PCR primer design. Nucleic Acids Res (2003) 3.55
DNA methylation profiling identifies CG methylation clusters in Arabidopsis genes. Curr Biol (2005) 3.54
Phylogenomics of the nucleosome. Nat Struct Biol (2003) 3.52
DNA demethylation by DNA repair. Trends Genet (2009) 3.49
Single-nucleotide mutations for plant functional genomics. Annu Rev Plant Biol (2003) 3.39
Genome-wide profiling of DNA methylation reveals transposon targets of CHROMOMETHYLASE3. Curr Biol (2002) 3.37
Extensive demethylation of repetitive elements during seed development underlies gene imprinting. Science (2009) 3.33
A comprehensive map of insulator elements for the Drosophila genome. PLoS Genet (2010) 3.25
Tetrameric structure of centromeric nucleosomes in interphase Drosophila cells. PLoS Biol (2007) 3.25
Histone H3 variants specify modes of chromatin assembly. Proc Natl Acad Sci U S A (2002) 3.06
Centromeric localization and adaptive evolution of an Arabidopsis histone H3 variant. Plant Cell (2002) 2.72
Regulation of nucleosome dynamics by histone modifications. Nat Struct Mol Biol (2013) 2.71
Spreading of silent chromatin: inaction at a distance. Nat Rev Genet (2006) 2.64
Stochastic and epigenetic changes of gene expression in Arabidopsis polyploids. Genetics (2004) 2.62
Parent-dependent loss of gene silencing during interspecies hybridization. Curr Biol (2006) 2.58
Discovery of induced point mutations in maize genes by TILLING. BMC Plant Biol (2004) 2.57
A modified TILLING approach to detect induced mutations in tetraploid and hexaploid wheat. BMC Plant Biol (2009) 2.57
Major evolutionary transitions in centromere complexity. Cell (2009) 2.49
Efficient discovery of DNA polymorphisms in natural populations by Ecotilling. Plant J (2004) 2.45
Remodeling of DNA methylation and phenotypic and transcriptional changes in synthetic Arabidopsis allotetraploids. Plant Physiol (2002) 2.41
TILLING. Traditional mutagenesis meets functional genomics. Plant Physiol (2004) 2.29
Genomic changes in synthetic Arabidopsis polyploids. Plant J (2005) 2.26
A simple method for gene expression and chromatin profiling of individual cell types within a tissue. Dev Cell (2010) 2.24
Epigenome characterization at single base-pair resolution. Proc Natl Acad Sci U S A (2011) 2.22
Conflict begets complexity: the evolution of centromeres. Curr Opin Genet Dev (2002) 2.14
Mismatch cleavage by single-strand specific nucleases. Nucleic Acids Res (2004) 2.14
TILLING to detect induced mutations in soybean. BMC Plant Biol (2008) 2.13
Genome-wide analysis of DNA methylation patterns. Development (2007) 2.13
Chromosomal locus rearrangements are a rapid response to formation of the allotetraploid Arabidopsis suecica genome. Proc Natl Acad Sci U S A (2004) 2.12
A protocol for TILLING and Ecotilling in plants and animals. Nat Protoc (2006) 2.09
Chromatin immunoprecipitation reveals that the 180-bp satellite repeat is the key functional DNA element of Arabidopsis thaliana centromeres. Genetics (2003) 2.05
Maize centromeres: organization and functional adaptation in the genetic background of oat. Plant Cell (2004) 2.01
Chaperone-mediated assembly of centromeric chromatin in vitro. Proc Natl Acad Sci U S A (2006) 1.98
Distinct HP1 and Su(var)3-9 complexes bind to sets of developmentally coexpressed genes depending on chromosomal location. Genes Dev (2003) 1.96
Aneuploidy and genetic variation in the Arabidopsis thaliana triploid response. Genetics (2005) 1.94
TILLING: practical single-nucleotide mutation discovery. Plant J (2006) 1.94
Adaptive evolution of centromere proteins in plants and animals. J Biol (2004) 1.90
The INTACT method for cell type-specific gene expression and chromatin profiling in Arabidopsis thaliana. Nat Protoc (2010) 1.87
Comorbid bipolar disorder and panic disorder in families with a high prevalence of bipolar disorder. Am J Psychiatry (2002) 1.87
A unified phylogeny-based nomenclature for histone variants. Epigenetics Chromatin (2012) 1.82
Inhibition of autophagy in mitotic animal cells. Traffic (2002) 1.81
Structure, dynamics, and evolution of centromeric nucleosomes. Proc Natl Acad Sci U S A (2007) 1.81
Maintenance of chromatin states: an open-and-shut case. Curr Opin Cell Biol (2003) 1.72
High-throughput TILLING for functional genomics. Methods Mol Biol (2003) 1.70
Changes in H2A.Z occupancy and DNA methylation during B-cell lymphomagenesis. Genome Res (2010) 1.69
The effect of stress on genome regulation and structure. Ann Bot (2004) 1.66
Centromere targeting element within the histone fold domain of Cid. Mol Cell Biol (2002) 1.64
PARSESNP: A tool for the analysis of nucleotide polymorphisms. Nucleic Acids Res (2003) 1.63
Epigenetic consequences of nucleosome dynamics. Cell (2002) 1.60
Doxorubicin enhances nucleosome turnover around promoters. Curr Biol (2013) 1.58
Positive selection drives the evolution of rhino, a member of the heterochromatin protein 1 family in Drosophila. PLoS Genet (2005) 1.57
Chromatin and siRNA pathways cooperate to maintain DNA methylation of small transposable elements in Arabidopsis. Genome Biol (2005) 1.55
Automated band mapping in electrophoretic gel images using background information. Nucleic Acids Res (2005) 1.49
Recurrent evolution of DNA-binding motifs in the Drosophila centromeric histone. Proc Natl Acad Sci U S A (2002) 1.48
Tripartite organization of centromeric chromatin in budding yeast. Proc Natl Acad Sci U S A (2011) 1.47
Two callose synthases, GSL1 and GSL5, play an essential and redundant role in plant and pollen development and in fertility. Plant Mol Biol (2005) 1.47
Genomic analysis of parent-of-origin allelic expression in Arabidopsis thaliana seeds. PLoS One (2011) 1.45
Mandating nurse staffing in Pennsylvania: more than a numbers game. J Nurs Adm (2009) 1.42
Germline histone dynamics and epigenetics. Curr Opin Cell Biol (2007) 1.42
Histone H3.3 variant dynamics in the germline of Caenorhabditis elegans. PLoS Genet (2006) 1.42
H2A.Z nucleosomes enriched over active genes are homotypic. Nat Struct Mol Biol (2010) 1.41
DNA methylation dynamics in plant genomes. Biochim Biophys Acta (2007) 1.41
A differential dosage hypothesis for parental effects in seed development. Plant Cell (2004) 1.37