Published in BMC Plant Biol on January 24, 2008
A modified TILLING approach to detect induced mutations in tetraploid and hexaploid wheat. BMC Plant Biol (2009) 2.57
Development and characterization of an oat TILLING-population and identification of mutations in lignin and beta-glucan biosynthesis genes. BMC Plant Biol (2010) 1.82
Reverse genetics in zebrafish by TILLING. Brief Funct Genomic Proteomic (2008) 1.73
Applying genotyping (TILLING) and phenotyping analyses to elucidate gene function in a chemically induced sorghum mutant population. BMC Plant Biol (2008) 1.57
A comparative analysis of insertional effects in genetically engineered plants: considerations for pre-market assessments. Transgenic Res (2014) 1.57
Phenotypic and genomic analyses of a fast neutron mutant population resource in soybean. Plant Physiol (2011) 1.45
A soybean cyst nematode resistance gene points to a new mechanism of plant resistance to pathogens. Nature (2012) 1.42
Engineering melon plants with improved fruit shelf life using the TILLING approach. PLoS One (2010) 1.37
High-throughput detection of induced mutations and natural variation using KeyPoint technology. PLoS One (2009) 1.35
Implementation of two high through-put techniques in a novel application: detecting point mutations in large EMS mutated plant populations. Plant Methods (2009) 1.34
A new mutant genetic resource for tomato crop improvement by TILLING technology. BMC Res Notes (2010) 1.29
Targeted mutagenesis of duplicated genes in soybean with zinc-finger nucleases. Plant Physiol (2011) 1.29
TILLING: a shortcut in functional genomics. J Appl Genet (2011) 1.16
Retention of induced mutations in a Drosophila reverse-genetic resource. Genetics (2008) 1.14
Functional genomics of soybean for improvement of productivity in adverse conditions. Funct Integr Genomics (2010) 1.12
New sources of soybean seed meal and oil composition traits identified through TILLING. BMC Plant Biol (2009) 1.12
TILLING in Lotus japonicus identified large allelic series for symbiosis genes and revealed a bias in functionally defective ethyl methanesulfonate alleles toward glycine replacements. Plant Physiol (2009) 1.09
Simultaneous mutation detection of three homoeologous genes in wheat by High Resolution Melting analysis and Mutation Surveyor. BMC Plant Biol (2009) 1.09
Characterization of highly efficient heavy-ion mutagenesis in Arabidopsis thaliana. BMC Plant Biol (2011) 1.07
Development and characterization of a new TILLING population of common bread wheat (Triticum aestivum L.). PLoS One (2012) 1.04
A diploid wheat TILLING resource for wheat functional genomics. BMC Plant Biol (2012) 1.02
Towards a TILLING platform for functional genomics in Piel de Sapo melons. BMC Res Notes (2011) 1.02
A high-density collection of EMS-induced mutations for TILLING in Landsberg erecta genetic background of Arabidopsis. BMC Plant Biol (2009) 1.00
TILLING for allergen reduction and improvement of quality traits in peanut (Arachis hypogaea L.). BMC Plant Biol (2011) 0.99
Targeted mutagenesis in soybean using the CRISPR-Cas9 system. Sci Rep (2015) 0.98
Polyploid genome of Camelina sativa revealed by isolation of fatty acid synthesis genes. BMC Plant Biol (2010) 0.98
Statistical mutation calling from sequenced overlapping DNA pools in TILLING experiments. BMC Bioinformatics (2011) 0.97
Establishment of a soybean (Glycine max Merr. L) transposon-based mutagenesis repository. Planta (2008) 0.96
Mutagenesis and beyond! Tools for understanding legume biology. Plant Physiol (2009) 0.96
Application of TILLING and EcoTILLING as Reverse Genetic Approaches to Elucidate the Function of Genes in Plants and Animals. Curr Genomics (2008) 0.96
Tnt1 retrotransposon mutagenesis: a tool for soybean functional genomics. Plant Physiol (2012) 0.94
iTILLING: a personalized approach to the identification of induced mutations in Arabidopsis. Plant Physiol (2010) 0.93
Identification of rice transcription factors associated with drought tolerance using the Ecotilling method. PLoS One (2012) 0.89
Soybean cyst nematode resistance in soybean is independent of the Rhg4 locus LRR-RLK gene. Funct Integr Genomics (2011) 0.89
Potential of a mutant-based reverse genetic approach for functional genomics and molecular breeding in soybean. Breed Sci (2012) 0.88
Mutagenesis as a tool in plant genetics, functional genomics, and breeding. Int J Plant Genomics (2012) 0.87
Discovery of nucleotide polymorphisms in the Musa gene pool by Ecotilling. Theor Appl Genet (2010) 0.87
Production of a high-efficiency TILLING population through polyploidization. Plant Physiol (2013) 0.86
High-throughput discovery of mutations in tef semi-dwarfing genes by next-generation sequencing analysis. Genetics (2012) 0.85
Rapid identification and recovery of ENU-induced mutations with next-generation sequencing and Paired-End Low-Error analysis. BMC Genomics (2015) 0.85
Natural and artificial mutants as valuable resources for functional genomics and molecular breeding. Int J Biol Sci (2010) 0.83
Deletions of the SACPD-C locus elevate seed stearic acid levels but also result in fatty acid and morphological alterations in nitrogen fixing nodules. BMC Plant Biol (2014) 0.82
Construction of a high-density mutant library in soybean and development of a mutant retrieval method using amplicon sequencing. BMC Genomics (2015) 0.82
Genomics approaches for crop improvement against abiotic stress. ScientificWorldJournal (2013) 0.82
Updating the Micro-Tom TILLING platform. Breed Sci (2013) 0.81
A mutant Brassica napus (canola) population for the identification of new genetic diversity via TILLING and next generation sequencing. PLoS One (2013) 0.81
NEATTILL: A simplified procedure for nucleic acid extraction from arrayed tissue for TILLING and other high-throughput reverse genetic applications. Plant Methods (2010) 0.80
Ion Torrent sequencing as a tool for mutation discovery in the flax (Linum usitatissimum L.) genome. Plant Methods (2015) 0.78
Fast neutron-induced structural rearrangements at a soybean NAP1 locus result in gnarled trichomes. Theor Appl Genet (2016) 0.77
pENCODE: a plant encyclopedia of DNA elements. Annu Rev Genet (2014) 0.77
New approach for fish breeding by chemical mutagenesis: establishment of TILLING method in fugu (Takifugu rubripes) with ENU mutagenesis. BMC Genomics (2013) 0.77
Discovery of rare mutations in extensively pooled DNA samples using multiple target enrichment. Plant Biotechnol J (2014) 0.77
Quantitative trait loci from identification to exploitation for crop improvement. Plant Cell Rep (2017) 0.77
MicroRNA Maturation and MicroRNA Target Gene Expression Regulation Are Severely Disrupted in Soybean dicer-like1 Double Mutants. G3 (Bethesda) (2015) 0.76
Exploring Genetic Diversity in Plants Using High-Throughput Sequencing Techniques. Curr Genomics (2016) 0.75
Validation of doubled haploid plants by enzymatic mismatch cleavage. Plant Methods (2013) 0.75
Development and utilization of a new chemically-induced soybean library with a high mutation density. J Integr Plant Biol (2016) 0.75
Genotyping-by-Sequencing Based Investigation of the Genetic Architecture Responsible for a ~7-Fold Increase in Soybean Seed Stearic Acid. G3 (Bethesda) (2016) 0.75
Fighting Asian Soybean Rust. Front Plant Sci (2016) 0.75
Mutations in SACPD-C result in a range of elevated stearic acid concentration in soybean seed. PLoS One (2014) 0.75
Mutagenesis and TILLING to Dissect Gene Function in Plants. Curr Genomics (2016) 0.75
Lotus Base: An integrated information portal for the model legume Lotus japonicus. Sci Rep (2016) 0.75
COTIP: Cotton TILLING Platform, a Resource for Plant Improvement and Reverse Genetic Studies. Front Plant Sci (2016) 0.75
Characterization of the FAD2 Gene Family in Soybean Reveals the Limitations of Gel-Based TILLING in Genes with High Copy Number. Front Plant Sci (2017) 0.75
The endogenous transposable element Tgm9 is suitable for generating knockout mutants for functional analyses of soybean genes and genetic improvement in soybean. PLoS One (2017) 0.75
Primer3 on the WWW for general users and for biologist programmers. Methods Mol Biol (2000) 128.08
Targeting induced local lesions IN genomes (TILLING) for plant functional genomics. Plant Physiol (2000) 4.66
Large-scale discovery of induced point mutations with high-throughput TILLING. Genome Res (2003) 4.39
Spectrum of chemically induced mutations from a large-scale reverse-genetic screen in Arabidopsis. Genetics (2003) 3.70
Isolation and properties of soybean [Glycine max (L.) Merr.] mutants that nodulate in the presence of high nitrate concentrations. Proc Natl Acad Sci U S A (1985) 3.27
A reverse genetic, nontransgenic approach to wheat crop improvement by TILLING. Nat Biotechnol (2004) 3.03
Mutation detection using a novel plant endonuclease. Nucleic Acids Res (1998) 2.78
A structured mutant population for forward and reverse genetics in Barley (Hordeum vulgare L.). Plant J (2004) 2.77
Discovery of induced point mutations in maize genes by TILLING. BMC Plant Biol (2004) 2.57
Discovery of chemically induced mutations in rice by TILLING. BMC Plant Biol (2007) 2.46
A TILLING reverse genetics tool and a web-accessible collection of mutants of the legume Lotus japonicus. Plant Physiol (2003) 2.30
Blocks-based methods for detecting protein homology. Electrophoresis (2000) 2.19
Chemical- and irradiation-induced mutants of indica rice IR64 for forward and reverse genetics. Plant Mol Biol (2005) 1.85
Target-selected mutant screen by TILLING in Drosophila. Genome Res (2005) 1.83
DNA base changes and alkylation following in vivo exposure of Escherichia coli to N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea. Proc Natl Acad Sci U S A (1987) 1.81
High-throughput TILLING for functional genomics. Methods Mol Biol (2003) 1.70
Automated band mapping in electrophoretic gel images using background information. Nucleic Acids Res (2005) 1.49
RNA interference of soybean isoflavone synthase genes leads to silencing in tissues distal to the transformation site and to enhanced susceptibility to Phytophthora sojae. Plant Physiol (2005) 1.42
Isolation of ethylene-insensitive soybean mutants that are altered in pathogen susceptibility and gene-for-gene disease resistance Plant Physiol (1999) 1.33
Recent advances in legume transformation. Plant Physiol (2003) 1.31
Lotus japonicus: legume research in the fast lane. Trends Plant Sci (2005) 1.30
High-throughput discovery of rare human nucleotide polymorphisms by Ecotilling. Nucleic Acids Res (2006) 1.28
High-efficiency induction of soybean hairy roots and propagation of the soybean cyst nematode. Planta (2000) 1.26
RNAi-mediated silencing of the myo-inositol-1-phosphate synthase gene (GmMIPS1) in transgenic soybean inhibited seed development and reduced phytate content. Planta (2006) 1.19
Efficient soybean transformation using hygromycin B selection in the cotyledonary-node method. Planta (2002) 1.17
Identification and functional characterization of a leucine-rich repeat receptor-like kinase gene that is involved in regulation of soybean leaf senescence. Plant Mol Biol (2006) 0.94
Transformation of 12 different plasmids into soybean via particle bombardment. Plant Cell Rep (1996) 0.90
Soybean (Glycine max) transformation using immature cotyledon explants. Methods Mol Biol (2006) 0.87
Soybean (Glycine max) transformation using mature cotyledonary node explants. Methods Mol Biol (2006) 0.85
Different mutation frequencies and spectra among organs by N-methyl-N-nitrosourea in rpsL (strA) transgenic mice. Jpn J Cancer Res (2000) 0.84
Molecular control of gene co-suppression in transgenic soybean via particle bombardment. J Biochem Mol Biol (2006) 0.82
SIFT: Predicting amino acid changes that affect protein function. Nucleic Acids Res (2003) 52.26
Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm. Nat Protoc (2009) 38.62
Accounting for human polymorphisms predicted to affect protein function. Genome Res (2002) 14.10
Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science (2010) 12.39
Genome-wide analysis of Arabidopsis thaliana DNA methylation uncovers an interdependence between methylation and transcription. Nat Genet (2006) 11.88
Unlocking the secrets of the genome. Nature (2009) 11.80
Predicting the effects of amino acid substitutions on protein function. Annu Rev Genomics Hum Genet (2006) 9.80
The histone variant H3.3 marks active chromatin by replication-independent nucleosome assembly. Mol Cell (2002) 9.80
Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project. Science (2010) 9.78
The epigenetic progenitor origin of human cancer. Nat Rev Genet (2006) 9.65
Genome-scale profiling of histone H3.3 replacement patterns. Nat Genet (2005) 7.22
Understanding mechanisms of novel gene expression in polyploids. Trends Genet (2003) 4.90
Histone H3.3 is enriched in covalent modifications associated with active chromatin. Proc Natl Acad Sci U S A (2004) 4.88
Genome-wide kinetics of nucleosome turnover determined by metabolic labeling of histones. Science (2010) 4.72
Centromeric nucleosomes induce positive DNA supercoils. Cell (2009) 4.57
DNA demethylation in the Arabidopsis genome. Proc Natl Acad Sci U S A (2007) 4.55
SIFT web server: predicting effects of amino acid substitutions on proteins. Nucleic Acids Res (2012) 4.45
Histone variants--ancient wrap artists of the epigenome. Nat Rev Mol Cell Biol (2010) 4.45
Large-scale discovery of induced point mutations with high-throughput TILLING. Genome Res (2003) 4.39
Histone H2A.Z and DNA methylation are mutually antagonistic chromatin marks. Nature (2008) 4.20
Histone replacement marks the boundaries of cis-regulatory domains. Science (2007) 4.06
Genomewide nonadditive gene regulation in Arabidopsis allotetraploids. Genetics (2005) 3.78
Spectrum of chemically induced mutations from a large-scale reverse-genetic screen in Arabidopsis. Genetics (2003) 3.70
Sequencing of a rice centromere uncovers active genes. Nat Genet (2004) 3.66
CODEHOP (COnsensus-DEgenerate Hybrid Oligonucleotide Primer) PCR primer design. Nucleic Acids Res (2003) 3.55
DNA methylation profiling identifies CG methylation clusters in Arabidopsis genes. Curr Biol (2005) 3.54
Phylogenomics of the nucleosome. Nat Struct Biol (2003) 3.52
DNA demethylation by DNA repair. Trends Genet (2009) 3.49
Single-nucleotide mutations for plant functional genomics. Annu Rev Plant Biol (2003) 3.39
Genome-wide profiling of DNA methylation reveals transposon targets of CHROMOMETHYLASE3. Curr Biol (2002) 3.37
Extensive demethylation of repetitive elements during seed development underlies gene imprinting. Science (2009) 3.33
A comprehensive map of insulator elements for the Drosophila genome. PLoS Genet (2010) 3.25
Tetrameric structure of centromeric nucleosomes in interphase Drosophila cells. PLoS Biol (2007) 3.25
Histone H3 variants specify modes of chromatin assembly. Proc Natl Acad Sci U S A (2002) 3.06
Centromeric localization and adaptive evolution of an Arabidopsis histone H3 variant. Plant Cell (2002) 2.72
Regulation of nucleosome dynamics by histone modifications. Nat Struct Mol Biol (2013) 2.71
Spreading of silent chromatin: inaction at a distance. Nat Rev Genet (2006) 2.64
Stochastic and epigenetic changes of gene expression in Arabidopsis polyploids. Genetics (2004) 2.62
Parent-dependent loss of gene silencing during interspecies hybridization. Curr Biol (2006) 2.58
Discovery of induced point mutations in maize genes by TILLING. BMC Plant Biol (2004) 2.57
A modified TILLING approach to detect induced mutations in tetraploid and hexaploid wheat. BMC Plant Biol (2009) 2.57
Major evolutionary transitions in centromere complexity. Cell (2009) 2.49
Discovery of chemically induced mutations in rice by TILLING. BMC Plant Biol (2007) 2.46
Efficient discovery of DNA polymorphisms in natural populations by Ecotilling. Plant J (2004) 2.45
Remodeling of DNA methylation and phenotypic and transcriptional changes in synthetic Arabidopsis allotetraploids. Plant Physiol (2002) 2.41
TILLING. Traditional mutagenesis meets functional genomics. Plant Physiol (2004) 2.29
Genomic changes in synthetic Arabidopsis polyploids. Plant J (2005) 2.26
A simple method for gene expression and chromatin profiling of individual cell types within a tissue. Dev Cell (2010) 2.24
Epigenome characterization at single base-pair resolution. Proc Natl Acad Sci U S A (2011) 2.22
Conflict begets complexity: the evolution of centromeres. Curr Opin Genet Dev (2002) 2.14
Mismatch cleavage by single-strand specific nucleases. Nucleic Acids Res (2004) 2.14
Genome-wide analysis of DNA methylation patterns. Development (2007) 2.13
Chromosomal locus rearrangements are a rapid response to formation of the allotetraploid Arabidopsis suecica genome. Proc Natl Acad Sci U S A (2004) 2.12
A protocol for TILLING and Ecotilling in plants and animals. Nat Protoc (2006) 2.09
Chromatin immunoprecipitation reveals that the 180-bp satellite repeat is the key functional DNA element of Arabidopsis thaliana centromeres. Genetics (2003) 2.05
Maize centromeres: organization and functional adaptation in the genetic background of oat. Plant Cell (2004) 2.01
Chaperone-mediated assembly of centromeric chromatin in vitro. Proc Natl Acad Sci U S A (2006) 1.98
Distinct HP1 and Su(var)3-9 complexes bind to sets of developmentally coexpressed genes depending on chromosomal location. Genes Dev (2003) 1.96
Aneuploidy and genetic variation in the Arabidopsis thaliana triploid response. Genetics (2005) 1.94
TILLING: practical single-nucleotide mutation discovery. Plant J (2006) 1.94
Adaptive evolution of centromere proteins in plants and animals. J Biol (2004) 1.90
The INTACT method for cell type-specific gene expression and chromatin profiling in Arabidopsis thaliana. Nat Protoc (2010) 1.87
A unified phylogeny-based nomenclature for histone variants. Epigenetics Chromatin (2012) 1.82
Structure, dynamics, and evolution of centromeric nucleosomes. Proc Natl Acad Sci U S A (2007) 1.81
A BAC- and BIBAC-based physical map of the soybean genome. Genome Res (2004) 1.73
Maintenance of chromatin states: an open-and-shut case. Curr Opin Cell Biol (2003) 1.72
The R1 gene for potato resistance to late blight (Phytophthora infestans) belongs to the leucine zipper/NBS/LRR class of plant resistance genes. Plant J (2002) 1.71
High-throughput TILLING for functional genomics. Methods Mol Biol (2003) 1.70
Changes in H2A.Z occupancy and DNA methylation during B-cell lymphomagenesis. Genome Res (2010) 1.69
Cytokinins play opposite roles in lateral root formation, and nematode and Rhizobial symbioses. Plant J (2004) 1.66
The effect of stress on genome regulation and structure. Ann Bot (2004) 1.66
Centromere targeting element within the histone fold domain of Cid. Mol Cell Biol (2002) 1.64
Epigenetic consequences of nucleosome dynamics. Cell (2002) 1.60
Doxorubicin enhances nucleosome turnover around promoters. Curr Biol (2013) 1.58
Positive selection drives the evolution of rhino, a member of the heterochromatin protein 1 family in Drosophila. PLoS Genet (2005) 1.57
Chromatin and siRNA pathways cooperate to maintain DNA methylation of small transposable elements in Arabidopsis. Genome Biol (2005) 1.55
Automated band mapping in electrophoretic gel images using background information. Nucleic Acids Res (2005) 1.49
Recurrent evolution of DNA-binding motifs in the Drosophila centromeric histone. Proc Natl Acad Sci U S A (2002) 1.48
Tripartite organization of centromeric chromatin in budding yeast. Proc Natl Acad Sci U S A (2011) 1.47
Two callose synthases, GSL1 and GSL5, play an essential and redundant role in plant and pollen development and in fertility. Plant Mol Biol (2005) 1.47
MiR-30-regulated autophagy mediates angiotensin II-induced myocardial hypertrophy. PLoS One (2013) 1.46
Genomic analysis of parent-of-origin allelic expression in Arabidopsis thaliana seeds. PLoS One (2011) 1.45
Germline histone dynamics and epigenetics. Curr Opin Cell Biol (2007) 1.42
A soybean cyst nematode resistance gene points to a new mechanism of plant resistance to pathogens. Nature (2012) 1.42
Histone H3.3 variant dynamics in the germline of Caenorhabditis elegans. PLoS Genet (2006) 1.42
H2A.Z nucleosomes enriched over active genes are homotypic. Nat Struct Mol Biol (2010) 1.41
DNA methylation dynamics in plant genomes. Biochim Biophys Acta (2007) 1.41