Published in Med Hypotheses on April 27, 2007
Management of acute liver failure. Nat Rev Gastroenterol Hepatol (2009) 1.32
Ammonia toxicity to the brain. J Inherit Metab Dis (2012) 1.04
Drug-induced acute liver failure. Clin Liver Dis (2013) 1.03
Changing face of hepatic encephalopathy: role of inflammation and oxidative stress. World J Gastroenterol (2010) 1.00
Current trends in the treatment of hepatic encephalopathy. Ther Clin Risk Manag (2009) 0.90
A current review of the diagnostic and treatment strategies of hepatic encephalopathy. Int J Hepatol (2012) 0.88
Management of hepatic encephalopathy. Int J Hepatol (2011) 0.82
Sodium benzoate for treatment of hepatic encephalopathy. Gastroenterol Hepatol (N Y) (2013) 0.82
Hepatic encephalopathy: an updated approach from pathogenesis to treatment. Med Sci Monit (2011) 0.81
Evidence of a vicious cycle in glutamine synthesis and breakdown in pathogenesis of hepatic encephalopathy-therapeutic perspectives. Metab Brain Dis (2013) 0.80
Impaired gluconeogenesis in a porcine model of paracetamol induced acute liver failure. World J Gastroenterol (2011) 0.79
Covert and Overt Hepatic Encephalopathy: Diagnosis and Management. Clin Gastroenterol Hepatol (2015) 0.79
(1)H nuclear magnetic resonance spectroscopy-based metabonomic study in patients with cirrhosis and hepatic encephalopathy. World J Hepatol (2015) 0.79
Hepatic encephalopathy therapy: An overview. World J Gastrointest Pharmacol Ther (2010) 0.78
The brain in acute on chronic liver failure. Metab Brain Dis (2014) 0.78
Hepatic Encephalopathy: From the Pathogenesis to the New Treatments. ISRN Hepatol (2014) 0.75
Ammonia mediates cortical hemichannel dysfunction in rodent models of chronic liver disease. Hepatology (2017) 0.75
A morphological method for ammonia detection in liver. PLoS One (2017) 0.75
Managing complications in cirrhotic patients. United European Gastroenterol J (2015) 0.75
Impact of ornithine phenylacetate (OCR-002) in lowering plasma ammonia after upper gastrointestinal bleeding in cirrhotic patients. Therap Adv Gastroenterol (2016) 0.75
Role of albumin in cirrhosis: from a hospitalist's perspective. J Community Hosp Intern Med Perspect (2017) 0.75
Stromal gene signatures in large-B-cell lymphomas. N Engl J Med (2008) 11.34
Biomedical informatics: we are what we publish. Methods Inf Med (2013) 2.79
THE ELECTROCARDIOGRAM IN FRIEDREICH DISEASE. Br Heart J (1942) 2.39
GeneMANIA Cytoscape plugin: fast gene function predictions on the desktop. Bioinformatics (2010) 2.39
The accuracy of EUS-FNA in assessing mediastinal lymphadenopathy and staging patients with NSCLC. Eur Respir J (2005) 2.37
Submillimetre galaxies reside in dark matter haloes with masses greater than 3 × 10(11) solar masses. Nature (2011) 2.21
Hazards for elderly people admitted for respite ("holiday admissions") and social care ("social admissions"). Br Med J (Clin Res Ed) (1986) 2.19
Distinctive patterns of BCL6 molecular alterations and their functional consequences in different subgroups of diffuse large B-cell lymphoma. Leukemia (2007) 2.03
Musculoskeletal ultrasound training in rheumatology: the Belfast experience. Rheumatology (Oxford) (2005) 1.86
Insulin-like growth factor binding protein 1 stimulates cell migration and binds to the alpha 5 beta 1 integrin by means of its Arg-Gly-Asp sequence. Proc Natl Acad Sci U S A (1993) 1.85
Urban exposure to carbon monoxide. Arch Environ Health (1972) 1.79
Treatment-related chromosome abnormalities in human embryos. Hum Reprod (1997) 1.65
Videocinematography of fresh and cryopreserved embryos: a retrospective analysis of embryonic morphology and implantation. Fertil Steril (1989) 1.63
An evaluation of nebulized prostacyclin in patients with primary and secondary pulmonary hypertension. Eur Heart J (1997) 1.59
Role of ammonia and inflammation in minimal hepatic encephalopathy. Metab Brain Dis (2007) 1.57
Analysis of multidisciplinary lung cancer practice. Intern Med J (2007) 1.55
Focal neuronal migration disorders and intractable partial epilepsy: a study of 30 patients. Ann Neurol (1991) 1.45
The miRNA-17∼92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation. Leukemia (2011) 1.43
A comparison of two systems for assessing cerebral venous oxyhaemoglobin saturation during cardiopulmonary bypass in humans. Anaesthesia (1993) 1.42
Multiple pregnancy rate and embryo number transferred during in vitro fertilization. Am J Obstet Gynecol (1997) 1.42
N2-phenyldeoxyguanosine: a novel selective inhibitor of herpes simplex thymidine kinase. J Med Chem (1988) 1.40
FMD control strategies. Vet Rec (2001) 1.39
Materials and techniques for electrochemical biosensor design and construction. Biosens Bioelectron (2000) 1.34
Human menopausal gonadotropin/human chorionic gonadotropin follicular maturation for oocyte aspiration: phase II, 1981. Fertil Steril (1983) 1.33
Tumour necrosis factor alpha is an important mediator of portal and systemic haemodynamic derangements in alcoholic hepatitis. Gut (2003) 1.32
A blind randomised cross-over trial comparing metipranolol 0.3% with timolol 0.25% in open-angle glaucoma: a pilot study. Br J Ophthalmol (1986) 1.30
A decade of diabetes: keeping children out of hospital. BMJ (1993) 1.27
What are the implications of variation in root hair length on tolerance to phosphorus deficiency in combination with water stress in barley (Hordeum vulgare)? Ann Bot (2012) 1.26
Critical role for transcriptional repressor Snail2 in transformation by oncogenic RAS in colorectal carcinoma cells. Oncogene (2010) 1.24
The program for in vitro fertilization at Norfolk. Fertil Steril (1982) 1.21
Assisted hatching with or without bovine oviductal epithelial cell co-culture for poor prognosis in-vitro fertilization patients. Hum Reprod (1994) 1.19
Structure-activity relationships of N2-substituted guanines as inhibitors of HSV1 and HSV2 thymidine kinases. J Med Chem (1990) 1.19
Reproductive and other factors and risk of epithelial ovarian cancer: an Australian case-control study. Survey of Women's Health Study Group. Int J Cancer (1995) 1.18
Brain damage in dogs immediately following pulsatile and non-pulsatile blood flows in extracorporeal circulation. Thorax (1972) 1.18
Birth after cryopreservation of immature oocytes with subsequent in vitro maturation. Fertil Steril (1998) 1.15
Japanese fermented soybean food as the major determinant of the large geographic difference in circulating levels of vitamin K2: possible implications for hip-fracture risk. Nutrition (2001) 1.13
Reduced bone formation in UK Gulf War veterans: a bone histomorphometric study. J Clin Pathol (2002) 1.12
Interleukin 6 production by lipopolysaccharide-stimulated human fibroblasts is potently inhibited by naphthoquinone (vitamin K) compounds. Cytokine (1995) 1.12
Positive regulatory domain I binding factor 1 silences class II transactivator expression in multiple myeloma cells. J Biol Chem (2001) 1.11
Reinsemination by intracytoplasmic sperm injection of 1-day-old oocytes after complete conventional fertilization failure. Fertil Steril (1997) 1.08
The importance of the follicular phase to success and failure in in vitro fertilization. Fertil Steril (1983) 1.05
Surgery for early stage non-small cell lung cancer. Cochrane Database Syst Rev (2005) 1.05
Partial dissection of the zona pellucida of frozen-thawed human embryos may enhance blastocyst hatching, implantation, and pregnancy rates. Am J Obstet Gynecol (1991) 1.04
Carbon monoxide and driving skills. Arch Environ Health (1973) 1.03
Structure of bovine eye lens gammaD (gammaIIIb)-crystallin at 1.95 A. Acta Crystallogr D Biol Crystallogr (1996) 1.02
Pattern of developing the performance template. Br J Sports Med (2009) 1.01
Chemical removal of the outside of the zona pellucida of day 3 human embryos has no impact on implantation rate. J Assist Reprod Genet (1993) 1.01
Remote ischaemic preconditioning of the hind limb reduces experimental liver warm ischaemia-reperfusion injury. Br J Surg (2006) 0.99
Relationship between Heberden's nodes and underlying radiographic changes of osteoarthritis. Ann Rheum Dis (2005) 0.99
Prolyl hydroxylase inhibitor treatment confers whole-animal hypoxia tolerance. Acta Physiol (Oxf) (2007) 0.98
Identification of the forms of insulin-like growth factor-binding proteins produced by human fibroblasts and the mechanisms that regulate their secretion. J Biol Chem (1992) 0.98
Application of photodiode array UV detection in the development of stability-indicating LC methods: determination of mefenamic acid. J Pharm Biomed Anal (1990) 0.97
Effects of nitric oxide and peroxynitrite on the cytochrome oxidase K(m) for oxygen: implications for mitochondrial pathology. Biochim Biophys Acta (2000) 0.96
Quantitative structure-activity relationships of N2-phenylguanines as inhibitors of herpes simplex virus thymidine kinases. J Med Chem (1992) 0.96
Cancer of the cervix--old and young, now and then. Gynecol Oncol (1991) 0.96
Pharmacokinetically guided phase 1 trial of the IGF-1 receptor antagonist RG1507 in children with recurrent or refractory solid tumors. Clin Cancer Res (2010) 0.96
A novel element and a TEF-2-like element activate the major histocompatibility complex class II transactivator in B-lymphocytes. J Biol Chem (1999) 0.95
Structure to 1.9 A resolution of a complex with herpes simplex virus type-1 thymidine kinase of a novel, non-substrate inhibitor: X-ray crystallographic comparison with binding of aciclovir. FEBS Lett (1999) 0.95
Allopurinol pretreatment improves postoperative recovery and reduces lipid peroxidation in patients undergoing coronary artery bypass grafting. J Thorac Cardiovasc Surg (1994) 0.95
Rescuing transgene expression by co-integration. Biotechnology (N Y) (1992) 0.95
Identification of the sites of phosphorylation in insulin-like growth factor binding protein-1. Regulation of its affinity by phosphorylation of serine 101. J Biol Chem (1993) 0.94
Massive epistaxis due to pseudoaneurysm. Treated with detachable balloons. Arch Otolaryngol Head Neck Surg (1992) 0.94
Use of leeches in a case of severe periorbital haematoma. Br J Ophthalmol (1991) 0.93
Role of Toll-like receptors 2, 4, and 9 in mediating neutrophil dysfunction in alcoholic hepatitis. Am J Physiol Gastrointest Liver Physiol (2008) 0.93
A model to study total hepatic ischemia-reperfusion injury. Transplant Proc (2004) 0.92
Conversion of pig pancreas phospholipase A2 by protein engineering into enzyme active against Escherichia coli treated with the bactericidal/permeability-increasing protein. J Biol Chem (1991) 0.92
Implantation of embryos after partial opening of oocyte zona pellucida to facilitate sperm penetration. Lancet (1988) 0.92
In vitro and in vivo reactivity and specificity of fractions from sonicates of Mycobacterium tuberculosis separated by gradient acrylamide gel electrophoresis. Am Rev Respir Dis (1980) 0.92
Bacteriophage T4 and human type I DNA ligases relax DNA under joining conditions. Nucleic Acids Res (1993) 0.90
Towards open collaborative health informatics - The Role of free/libre open source principles. Contribution of the IMIA Open Source Health Informatics Working Group. Yearb Med Inform (2011) 0.90
Glucose sensor with improved haemocompatibilty. Biosens Bioelectron (2000) 0.89
Inhibition of DNA polymerase alpha by aphidicolin derivatives. Nucleic Acids Res (1988) 0.89
Coculture of human zygotes on fetal bovine uterine fibroblasts: embryonic morphology and implantation. Fertil Steril (1989) 0.89
In-vitro development and implantation of human embryos following culture on fetal bovine uterine fibroblast cells. Hum Reprod (1989) 0.89
Investigations of host defence in patients with sickle cell disease. Br J Haematol (1985) 0.89
Clinical application of human egg cryopreservation. Hum Reprod (1998) 0.89
Brain damage and mortality in dogs following pulsatile and non-pulsatile blood flows in extracorporeal circulation. Thorax (1972) 0.88
Preliminary experience with human oocyte cryopreservation using 1,2-propanediol and sucrose. Hum Reprod (1996) 0.88
Exercise-associated generation of PPARγ ligands activates PPARγ signaling events and upregulates genes related to lipid metabolism. J Appl Physiol (1985) (2011) 0.87
Effect of high-dose methylprednisolone therapy on phagocyte function in systemic lupus erythematosus. Ann Rheum Dis (1984) 0.87
Prognostic value of morphologic characteristics of cryopreserved embryos: a study using videocinematography. Fertil Steril (1988) 0.87
A study of mutation rates and the characterisation of intermediate, null and duplicated alleles for 13 Y chromosome STRs. Forensic Sci Int (2005) 0.86
Wrist compliance [proceedings]. J Physiol (1979) 0.86
Organizational issues in health informatics: a model approach. Int J Med Inform (1999) 0.86
The effect of vaccine on a closed epidemic of Hong Kong influenza. S Afr Med J (1970) 0.86
Double-blind, placebo controlled study of acetyl-l-carnitine in patients with Alzheimer's dementia. Curr Med Res Opin (1990) 0.86
An in-vacuum diffractometer for resonant elastic soft x-ray scattering. Rev Sci Instrum (2011) 0.86
The pH dependence of naturally occurring low-spin forms of methaemoglobin and metmyoglobin: an EPR study. Biochem J (2000) 0.86
Proteolytic cleavage of insulin-like growth factor binding protein 4 (IGFBP-4). Localization of cleavage site to non-homologous region of native IGFBP-4. J Biol Chem (1995) 0.86
Cobra cardiotoxins. Purification, effects on skeletal muscle and structure/activity relationships [published errtum appears in Eur J Biochem 1988 Feb 1;171(3):727]. Eur J Biochem (1987) 0.86
Review article: the molecular adsorbents recirculating system (MARS) in liver failure. Aliment Pharmacol Ther (2002) 0.86
Effects of bilateral adrenalectomy on the induction of learned helplessness behavior. Neuropsychopharmacology (1990) 0.85
Transgenic livestock as bioreactors: stable expression of human alpha-1-antitrypsin by a flock of sheep. Biotechnology (N Y) (1993) 0.85
Effect of coculture on subsequent survival and implantation of cryopreserved human embryos. J Assist Reprod Genet (1995) 0.85
Enhancement of outcome from intracytoplasmic sperm injection: does co-culture or assisted hatching improve implantation rates? Hum Reprod (1996) 0.85
Blastocyst transfer: a useful tool for reduction of high-order multiple gestations in a human assisted reproduction program. Am J Obstet Gynecol (2000) 0.85
Nucleoside analogs as non-substrate inhibitors of herpes simplex viruses thymidine kinase. Methods Find Exp Clin Pharmacol (1989) 0.85
Cystoid macular oedema with trypan blue use. Br J Ophthalmol (2004) 0.85
Pathological effects of intra-arterial blood transfusions in dogs. Cardiovasc Res (1975) 0.85