PubRank

Julio M Fernandez

Author PubWeight™ 73.01‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Stretching single talin rod molecules activates vinculin binding. Science 2009 8.11
2 The mechanical stability of ubiquitin is linkage dependent. Nat Struct Biol 2003 4.66
3 Reverse engineering of the giant muscle protein titin. Nature 2002 3.54
4 Linkage between ATP consumption and mechanical unfolding during the protein processing reactions of an AAA+ degradation machine. Cell 2003 3.33
5 The unfolding kinetics of ubiquitin captured with single-molecule force-clamp techniques. Proc Natl Acad Sci U S A 2004 3.18
6 The mechanical hierarchies of fibronectin observed with single-molecule AFM. J Mol Biol 2002 3.09
7 Probing the chemistry of thioredoxin catalysis with force. Nature 2007 2.17
8 Force-dependent chemical kinetics of disulfide bond reduction observed with single-molecule techniques. Proc Natl Acad Sci U S A 2006 1.95
9 Contour length and refolding rate of a small protein controlled by engineered disulfide bonds. Biophys J 2006 1.82
10 Mechanical unfolding intermediates observed by single-molecule force spectroscopy in a fibronectin type III module. J Mol Biol 2005 1.79
11 PEVK domain of titin: an entropic spring with actin-binding properties. J Struct Biol 2002 1.49
12 Mechanical design of the first proximal Ig domain of human cardiac titin revealed by single molecule force spectroscopy. J Mol Biol 2003 1.39
13 Ligand binding modulates the mechanical stability of dihydrofolate reductase. Biophys J 2005 1.35
14 Mechanical unfolding pathways of the enhanced yellow fluorescent protein revealed by single molecule force spectroscopy. J Biol Chem 2006 1.35
15 Single-molecule paleoenzymology probes the chemistry of resurrected enzymes. Nat Struct Mol Biol 2011 1.32
16 Simultaneous atomic force microscope and fluorescence measurements of protein unfolding using a calibrated evanescent wave. Proc Natl Acad Sci U S A 2004 1.30
17 Chair-boat transitions in single polysaccharide molecules observed with force-ramp AFM. Proc Natl Acad Sci U S A 2002 1.27
18 Single homopolypeptide chains collapse into mechanically rigid conformations. Proc Natl Acad Sci U S A 2009 1.25
19 Signatures of hydrophobic collapse in extended proteins captured with force spectroscopy. Proc Natl Acad Sci U S A 2007 1.24
20 Single-molecule force spectroscopy measurements of bond elongation during a bimolecular reaction. J Am Chem Soc 2008 1.22
21 Stepwise unfolding of ankyrin repeats in a single protein revealed by atomic force microscopy. Biophys J 2005 1.20
22 Dwell-time distribution analysis of polyprotein unfolding using force-clamp spectroscopy. Biophys J 2007 1.17
23 Collapse dynamics of single proteins extended by force. Biophys J 2010 1.16
24 The elasticity of individual titin PEVK exons measured by single molecule atomic force microscopy. J Biol Chem 2005 1.16
25 Modulation of titin-based stiffness by disulfide bonding in the cardiac titin N2-B unique sequence. Biophys J 2009 1.15
26 Retracted Solvent molecules bridge the mechanical unfolding transition state of a protein. Proc Natl Acad Sci U S A 2008 1.14
27 Diversity of chemical mechanisms in thioredoxin catalysis revealed by single-molecule force spectroscopy. Nat Struct Mol Biol 2009 1.11
28 Force dependency of biochemical reactions measured by single-molecule force-clamp spectroscopy. Nat Protoc 2013 1.08
29 Comparison of the protein-unfolding pathways between mitochondrial protein import and atomic-force microscopy measurements. Proc Natl Acad Sci U S A 2005 1.04
30 Nanomechanics of HaloTag tethers. J Am Chem Soc 2013 1.03
31 A single-molecule assay to directly identify solvent-accessible disulfide bonds and probe their effect on protein folding. J Am Chem Soc 2007 1.01
32 Cardiac titin: molecular basis of elasticity and cellular contribution to elastic and viscous stiffness components in myocardium. J Muscle Res Cell Motil 2002 0.96
33 Rate limit of protein elastic response is tether dependent. Proc Natl Acad Sci U S A 2012 0.94
34 Elasticity, structure, and relaxation of extended proteins under force. Proc Natl Acad Sci U S A 2013 0.94
35 Water's role in the force-induced unfolding of ubiquitin. Proc Natl Acad Sci U S A 2010 0.93
36 Dwell time analysis of a single-molecule mechanochemical reaction. Langmuir 2007 0.91
37 A single-molecule perspective on the role of solvent hydrogen bonds in protein folding and chemical reactions. Chemphyschem 2008 0.89
38 The mechanical fingerprint of a parallel polyprotein dimer. Biophys J 2006 0.89
39 The force-driven conformations of heparin studied with single molecule force microscopy. Biophys J 2003 0.88
40 Conservation of protein structure over four billion years. Structure 2013 0.87
41 Force-clamp spectroscopy detects residue co-evolution in enzyme catalysis. J Biol Chem 2008 0.87
42 Single-molecule force spectroscopy approach to enzyme catalysis. J Biol Chem 2010 0.83
43 Tandem repeating modular proteins avoid aggregation in single molecule force spectroscopy experiments. J Phys Chem A 2007 0.82
44 Extended Kalman filter estimates the contour length of a protein in single molecule atomic force microscopy experiments. Rev Sci Instrum 2009 0.80
45 Role of conservative mutations in protein multi-property adaptation. Biochem J 2010 0.80
46 Protein folding under mechanical forces: a physiological view. Physiology (Bethesda) 2013 0.79
47 Retracted Probing osmolyte participation in the unfolding transition state of a protein. Proc Natl Acad Sci U S A 2011 0.77
48 Probing the effect of force on HIV-1 receptor CD4. ACS Nano 2014 0.77
49 Fingerprinting DHFR in single-molecule AFM studies. Biophys J 2006 0.76