PubRank

Emmanuel Mignot

Author PubWeight™ 175.94‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index. PLoS Med 2004 11.17
2 Narcolepsy with cataplexy. Lancet 2007 4.81
3 History of the development of sleep medicine in the United States. J Clin Sleep Med 2005 4.22
4 Narcolepsy onset is seasonal and increased following the 2009 H1N1 pandemic in China. Ann Neurol 2011 4.09
5 Narcolepsy is strongly associated with the T-cell receptor alpha locus. Nat Genet 2009 3.33
6 Post-H1N1 narcolepsy-cataplexy. Sleep 2010 3.10
7 Elevated anti-streptococcal antibodies in patients with recent narcolepsy onset. Sleep 2009 3.06
8 Kleine-Levin syndrome: a systematic study of 108 patients. Ann Neurol 2008 3.03
9 Mapping multiple sclerosis susceptibility to the HLA-DR locus in African Americans. Am J Hum Genet 2003 2.71
10 Retracted CD4+ T cell autoimmunity to hypocretin/orexin and cross-reactivity to a 2009 H1N1 influenza A epitope in narcolepsy. Sci Transl Med 2013 2.51
11 Characterization of sleep in zebrafish and insomnia in hypocretin receptor mutants. PLoS Biol 2007 2.34
12 The role of hypocretins (orexins) in sleep regulation and narcolepsy. Annu Rev Neurosci 2002 2.28
13 Genetics of sleep and sleep disorders. Cell 2011 2.26
14 Variant between CPT1B and CHKB associated with susceptibility to narcolepsy. Nat Genet 2008 2.09
15 Correlates of serum C-reactive protein (CRP)--no association with sleep duration or sleep disordered breathing. Sleep 2007 1.88
16 DQB1*0602 predicts interindividual differences in physiologic sleep, sleepiness, and fatigue. Neurology 2010 1.86
17 Diagnosis, disease course, and management of patients with Kleine-Levin syndrome. Lancet Neurol 2012 1.83
18 The narcoleptic borderland: a multimodal diagnostic approach including cerebrospinal fluid levels of hypocretin-1 (orexin A). Sleep Med 2003 1.72
19 A link between short sleep and obesity: building the evidence for causation. Sleep 2005 1.67
20 Common variants in P2RY11 are associated with narcolepsy. Nat Genet 2010 1.65
21 Clinical and therapeutic aspects of childhood narcolepsy-cataplexy: a retrospective study of 51 children. Sleep 2010 1.64
22 Circadian and homeostatic regulation of hypocretin in a primate model: implications for the consolidation of wakefulness. J Neurosci 2003 1.64
23 Effects of IV and ICV hypocretin-1 (orexin A) in hypocretin receptor-2 gene mutated narcoleptic dogs and IV hypocretin-1 replacement therapy in a hypocretin-ligand-deficient narcoleptic dog. Sleep 2003 1.63
24 Clinical aspects of narcolepsy-cataplexy across ethnic groups. Sleep 2002 1.59
25 ImmunoChip study implicates antigen presentation to T cells in narcolepsy. PLoS Genet 2013 1.55
26 PER3 polymorphism predicts cumulative sleep homeostatic but not neurobehavioral changes to chronic partial sleep deprivation. PLoS One 2009 1.54
27 Mutations in DNMT1 cause autosomal dominant cerebellar ataxia, deafness and narcolepsy. Hum Mol Genet 2012 1.48
28 Anti-Tribbles homolog 2 (TRIB2) autoantibodies in narcolepsy are associated with recent onset of cataplexy. Sleep 2010 1.47
29 Complex movement disorders at disease onset in childhood narcolepsy with cataplexy. Brain 2011 1.35
30 Circadian and homeostatic regulation of structural synaptic plasticity in hypocretin neurons. Neuron 2010 1.33
31 Sleep/wake fragmentation disrupts metabolism in a mouse model of narcolepsy. J Physiol 2007 1.30
32 Relationship between CSF hypocretin levels and hypocretin neuronal loss. Exp Neurol 2003 1.28
33 Predictors of hypocretin (orexin) deficiency in narcolepsy without cataplexy. Sleep 2012 1.28
34 Diurnal variation of cerebrospinal fluid hypocretin-1 (Orexin-A) levels in control and depressed subjects. Biol Psychiatry 2003 1.27
35 Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1. PLoS Genet 2011 1.27
36 CSF hypocretin-1 assessment in sleep and neurological disorders. Lancet Neurol 2008 1.24
37 The diurnal rhythm of hypocretin in young and old F344 rats. Sleep 2004 1.22
38 Different periodicity and time structure of leg movements during sleep in narcolepsy/cataplexy and restless legs syndrome. Sleep 2006 1.19
39 The genetics of narcolepsy. Annu Rev Genomics Hum Genet 2003 1.18
40 The neurobiology of hypocretins (orexins), narcolepsy and related therapeutic interventions. Trends Pharmacol Sci 2006 1.18
41 Narcolepsy with hypocretin/orexin deficiency, infections and autoimmunity of the brain. Curr Opin Neurobiol 2011 1.17
42 Decreased CSF histamine in narcolepsy with and without low CSF hypocretin-1 in comparison to healthy controls. Sleep 2009 1.16
43 A study of the diagnostic utility of HLA typing, CSF hypocretin-1 measurements, and MSLT testing for the diagnosis of narcolepsy in 163 Korean patients with unexplained excessive daytime sleepiness. Sleep 2006 1.16
44 CSF versus serum leptin in narcolepsy: is there an effect of hypocretin deficiency? Sleep 2006 1.15
45 Genomic and functional conservation of sedative-hypnotic targets in the zebrafish. Pharmacogenet Genomics 2007 1.14
46 Body mass index-independent metabolic alterations in narcolepsy with cataplexy. Sleep 2009 1.13
47 DQB1*0301 and DQB1*0601 modulate narcolepsy susceptibility in Koreans. Hum Immunol 2006 1.12
48 Future of genetics of mood disorders research. Biol Psychiatry 2002 1.11
49 IGFBP3 colocalizes with and regulates hypocretin (orexin). PLoS One 2009 1.11
50 Cataplexy features in childhood narcolepsy. Mov Disord 2008 1.11
51 Regulation of hypocretin (orexin) expression in embryonic zebrafish. J Biol Chem 2006 1.10
52 Decreased incidence of childhood narcolepsy 2 years after the 2009 H1N1 winter flu pandemic. Ann Neurol 2012 1.09
53 Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic. PLoS Genet 2013 1.08
54 REM behavior disorder (RBD) can be one of the first symptoms of childhood narcolepsy. Sleep Med 2007 1.07
55 Sleep-wake regulation and hypocretin-melatonin interaction in zebrafish. Proc Natl Acad Sci U S A 2009 1.04
56 Increase of histaminergic tuberomammillary neurons in narcolepsy. Ann Neurol 2013 1.04
57 Daytime continuous polysomnography predicts MSLT results in hypersomnias of central origin. J Sleep Res 2012 1.04
58 The autoimmune basis of narcolepsy. Curr Opin Neurobiol 2013 1.03
59 Depression: relationships to sleep paralysis and other sleep disturbances in a community sample. J Sleep Res 2007 1.03
60 Nocturnal rapid eye movement sleep latency for identifying patients with narcolepsy/hypocretin deficiency. JAMA Neurol 2013 1.02
61 Early IVIg treatment has no effect on post-H1N1 narcolepsy phenotype or hypocretin deficiency. Neurology 2012 1.02
62 The genetics of sleep disorders. Lancet Neurol 2002 1.02
63 Genetic association, seasonal infections and autoimmune basis of narcolepsy. J Autoimmun 2013 0.99
64 Narcolepsy with cataplexy associated with holoprosencephaly misdiagnosed as epileptic drop attacks. Mov Disord 2010 0.98
65 Apolipoprotein E and obstructive sleep apnea: evaluating whether a candidate gene explains a linkage peak. Genet Epidemiol 2006 0.97
66 Lesions of the suprachiasmatic nucleus eliminate the daily rhythm of hypocretin-1 release. Sleep 2004 0.97
67 Increased hypocretin-1 (orexin-a) levels in cerebrospinal fluid of rats after short-term forced activity. Regul Pept 2004 0.96
68 Report of a case of immunosuppression with prednisone in an 8-year-old boy with an acute onset of hypocretin-deficiency narcolepsy. Sleep 2003 0.96
69 Periodic leg movements during sleep are associated with polymorphisms in BTBD9, TOX3/BC034767, MEIS1, MAP2K5/SKOR1, and PTPRD. Sleep 2014 0.95
70 Disrupted nighttime sleep in narcolepsy. J Clin Sleep Med 2013 0.95
71 Intravenous high-dose immunoglobulin treatment in recent onset childhood narcolepsy with cataplexy. J Neurol 2008 0.95
72 English translations of the first clinical reports on narcolepsy and cataplexy by Westphal and Gélineau in the late 19th century, with commentary. J Clin Sleep Med 2007 0.95
73 Characterization of two melanin-concentrating hormone genes in zebrafish reveals evolutionary and physiological links with the mammalian MCH system. J Comp Neurol 2009 0.94
74 Decreased hypocretin-1 (Orexin-A) levels in the cerebrospinal fluid of patients with myotonic dystrophy and excessive daytime sleepiness. Sleep 2003 0.94
75 Narcolepsy: genetic predisposition and neuropharmacological mechanisms. REVIEW ARTICLE. Sleep Med Rev 2000 0.94
76 Comparative expression of p2x receptors and ecto-nucleoside triphosphate diphosphohydrolase 3 in hypocretin and sensory neurons in zebrafish. Brain Res 2007 0.93
77 High prevalence of precocious puberty and obesity in childhood narcolepsy with cataplexy. Sleep 2013 0.92
78 Association of sleep disordered breathing and cognitive deficit in APOE ε4 carriers. Sleep 2013 0.92
79 Late-onset narcolepsy presenting as rapidly progressing muscle weakness: response to plasmapheresis. Ann Neurol 2005 0.91
80 Increasing length of wakefulness and modulation of hypocretin-1 in the wake-consolidated squirrel monkey. Am J Physiol Regul Integr Comp Physiol 2007 0.91
81 Month of birth as a risk factor for narcolepsy. Sleep 2003 0.91
82 Normal CSF hypocretin-1 (orexin A) levels in dementia with Lewy bodies associated with excessive daytime sleepiness. Eur Neurol 2004 0.91
83 A step forward for restless legs syndrome. Nat Genet 2007 0.90
84 Hypocretin receptor expression in canine and murine narcolepsy models and in hypocretin-ligand deficient human narcolepsy. Sleep 2008 0.90
85 Sleep and EEG features in genetic models of Down syndrome. Neurobiol Dis 2007 0.90
86 Polymorphisms within the canine MLPH gene are associated with dilute coat color in dogs. BMC Genet 2005 0.89
87 Catechol-O-methyltransferase Val158Met polymorphism associates with individual differences in sleep physiologic responses to chronic sleep loss. PLoS One 2011 0.89
88 HLA and hypocretin studies in Korean patients with narcolepsy. Sleep 2002 0.89
89 Presentations of primary hypersomnia in Chinese children. Sleep 2011 0.88
90 Narcolepsy and cataplexy. Handb Clin Neurol 2011 0.88
91 Clinical and polysomnographic course of childhood narcolepsy with cataplexy. Brain 2013 0.87
92 Voxel-based morphometry in hypocretin-deficient narcolepsy. Sleep 2003 0.87
93 CSF levels of hypocretin-1 (orexin-A) peak during early infancy in humans. Sleep 2012 0.86
94 Excessive daytime sleepiness: population and etiology versus nosology. Sleep Med Rev 2008 0.86
95 On the value of measuring CSF hypocretin-1 in diagnosing narcolepsy. Sleep 2003 0.86
96 Time-course of cerebrospinal fluid histamine in the wake-consolidated squirrel monkey. J Sleep Res 2011 0.86
97 The type III neurofilament peripherin is expressed in the tuberomammillary neurons of the mouse. BMC Neurosci 2008 0.85
98 Locomotor-dependent and -independent components to hypocretin-1 (orexin A) regulation in sleep-wake consolidating monkeys. J Physiol 2004 0.85
99 Angiotensin-converting enzyme, sleep-disordered breathing, and hypertension. Am J Respir Crit Care Med 2004 0.85
100 Behavioural and neurophysiological correlates of human cataplexy: a video-polygraphic study. Clin Neurophysiol 2009 0.84
101 T-box 3 is expressed in the adult mouse hypothalamus and medulla. Brain Res 2009 0.84
102 Post-streptococcal auto-antibodies inhibit protein disulfide isomerase and are associated with insulin resistance. PLoS One 2010 0.84
103 TCRA, P2RY11, and CPT1B/CHKB associations in Chinese narcolepsy. Sleep Med 2011 0.84
104 β2 adrenergic receptor polymorphisms and nocturnal blood pressure dipping status in the Wisconsin Sleep Cohort Study. J Am Soc Hypertens 2011 0.83
105 Increased hypocretin-1 levels in cerebrospinal fluid after REM sleep deprivation. Brain Res 2004 0.83
106 A novel de novo exon 21 DNMT1 mutation causes cerebellar ataxia, deafness, and narcolepsy in a Brazilian patient. Sleep 2013 0.83
107 DQB1*06:02 allele-specific expression varies by allelic dosage, not narcolepsy status. Hum Immunol 2012 0.83
108 Association of narcolepsy-cataplexy with HLA-DRB1 and DQB1 in Mexican patients: a relationship between HLA and gender is suggested. BMC Med Genet 2008 0.83
109 The association of angiotensin converting enzyme (ACE) polymorphisms with sleep apnea and hypertension. Sleep 2007 0.83
110 Genome-wide association study of HLA-DQB1*06:02 negative essential hypersomnia. PeerJ 2013 0.82
111 The roles of midbrain and diencephalic dopamine cell groups in the regulation of cataplexy in narcoleptic Dobermans. Neurobiol Dis 2004 0.82
112 Sympathetic and cardiovascular activity during cataplexy in narcolepsy. J Sleep Res 2008 0.81
113 Narcolepsy with cataplexy associated with nocturnal compulsive behaviors: a case-control study. Sleep 2011 0.81
114 Modafinil and γ-hydroxybutyrate have sleep state-specific pharmacological actions on hypocretin-1 physiology in a primate model of human sleep. Behav Pharmacol 2009 0.80
115 Transient total sleep loss in cerebral Whipple's disease: a longitudinal study. J Sleep Res 2002 0.80
116 Sleep well and stay slim: dream or reality? Ann Intern Med 2010 0.80
117 Analysis of onset location, laterality and propagation of cataplexy in canine narcolepsy. Psychiatry Clin Neurosci 2002 0.79
118 Reduced expression of TAC1, PENK and SOCS2 in Hcrtr-2 mutated narcoleptic dog brain. BMC Neurosci 2007 0.79
119 Sodium oxybate for excessive daytime sleepiness in narcolepsy-cataplexy. Sleep 2004 0.79
120 Sleep disturbances and hypocretin deficiency in Niemann-Pick disease type C. Sleep 2003 0.79
121 Narcolepsy with cataplexy mimicry: the strange case of two sisters. J Clin Sleep Med 2013 0.79
122 Dual cases of type 1 narcolepsy with schizophrenia and other psychotic disorders. J Clin Sleep Med 2014 0.79
123 Normal hypocretin-1 (orexin-A) cerebrospinal fluid level in a previously reported case of severe, life-long insomnia with motor hyperactivity. Sleep Med 2003 0.78
124 Transcriptional regulation of the hypocretin/orexin gene by NR6A1. Biochem Biophys Res Commun 2010 0.78
125 Analysis of extended HLA haplotypes in multiple sclerosis and narcolepsy families confirms a predisposing effect for the class I region in Tasmanian MS patients. Immunogenetics 2007 0.78
126 Article reviewed: Plasma orexin-A is lower in patients with narcolepsy. Sleep Med 2002 0.77
127 Hypocretin (orexin) neuropeptide precursor gene, HCRT, polymorphisms in early-onset narcolepsy with cataplexy. Sleep Med 2013 0.77
128 An update on the pharmacotherapy of excessive daytime sleepiness and cataplexy. Sleep Med Rev 2004 0.77
129 Effect of the prion 129 polymorphism on nocturnal sleep and insomnia complaints: a population-based study. J Sleep Res 2002 0.76
130 Sodium oxybate is an effective and safe treatment for narcolepsy. Sleep Med 2009 0.76
131 CSF hypocretin-1 levels in schizophrenics and controls: relationship to sleep architecture. Psychiatry Res 2002 0.76
132 The effect of hypocretin replacement therapy in a 3-year-old Weimaraner with narcolepsy. J Vet Intern Med 2004 0.76
133 Hypersomnolence and increased REM sleep with low cerebrospinal fluid hypocretin level in a patient after removal of craniopharyngioma. Sleep Med 2005 0.76
134 CSF hypocretin levels are normal in Huntington's disease patients. Sleep 2005 0.76
135 Faster REM sleep EEG and worse restedness in older insomniacs with HLA DQB1*0602. Psychiatry Res 2011 0.75
136 Letter to the editor regarding our previous publication: "Secondary narcolepsy in children with brain tumors," SLEEP 2002; 25:435-439. Sleep 2003 0.75
137 The treatment of sleep disorders. Neurotherapeutics 2012 0.75
138 Correction: Design and Validation of a Periodic Leg Movement Detector. PLoS One 2015 0.75
139 Post-streptococcal antibodies are associated with metabolic syndrome in a population-based cohort. PLoS One 2011 0.75
140 Undetectable CSF hypocretin-1 in "Hashimoto's encephalopathy" associated with coma. Neurology 2004 0.75
141 Autoimmunity in narcolepsy. Curr Opin Pulm Med 2017 0.75
142 Normal hypocretin-1 levels in the cerebrospinal fluid of patients with fatal familial insomnia. Sleep 2003 0.75
143 Episodic hypersomnia and unusual behaviors in a 14-year old adolescent. J Dev Behav Pediatr 2010 0.75
144 The MSLT is Repeatable in Narcolepsy Type 1 But Not Narcolepsy Type 2: A Retrospective Patient Study. J Clin Sleep Med 2017 0.75
145 Normal cerebrospinal fluid levels of hypocretin-1 (orexin A) in patients with fibromyalgia syndrome. Sleep Med 2007 0.75
146 [Not Available]. Hist Sci Med 2016 0.75
147 Episodic hypersomnia and unusual behaviors in a 14-year old adolescent. J Dev Behav Pediatr 2007 0.75