Published in Pharmacogenet Genomics on April 01, 2007
Characterization of sleep in zebrafish and insomnia in hypocretin receptor mutants. PLoS Biol (2007) 2.34
The genetic and molecular regulation of sleep: from fruit flies to humans. Nat Rev Neurosci (2009) 1.82
Unearthing the phylogenetic roots of sleep. Curr Biol (2008) 1.71
Adult zebrafish as a model organism for behavioural genetics. BMC Neurosci (2010) 1.57
Three-dimensional neurophenotyping of adult zebrafish behavior. PLoS One (2011) 1.37
Acute and chronic alcohol dose: population differences in behavior and neurochemistry of zebrafish. Genes Brain Behav (2009) 1.36
Zebrafish antipredatory responses: a future for translational research? Behav Brain Res (2009) 1.35
Use of zebrafish as a model to understand mechanisms of addiction and complex neurobehavioral phenotypes. Neurobiol Dis (2010) 1.20
Zebrafish Behavior in Novel Environments: Effects of Acute Exposure to Anxiolytic Compounds and Choice of Danio rerio Line. Int J Comp Psychol (2010) 1.12
Tracking zebrafish larvae in group--status and perspectives. Methods (2013) 1.07
Chemobehavioural phenomics and behaviour-based psychiatric drug discovery in the zebrafish. Brief Funct Genomic Proteomic (2008) 1.06
A second-generation device for automated training and quantitative behavior analyses of molecularly-tractable model organisms. PLoS One (2010) 1.02
Identification of a brain center whose activity discriminates a choice behavior in zebrafish. Proc Natl Acad Sci U S A (2011) 1.01
Dopamine receptor antagonism disrupts social preference in zebrafish: a strain comparison study. Amino Acids (2012) 0.93
Strain dependent gene expression and neurochemical levels in the brain of zebrafish: focus on a few alcohol related targets. Physiol Behav (2012) 0.89
Regulation of zebrafish sleep and arousal states: current and prospective approaches. Front Neural Circuits (2013) 0.84
Melatonin is required for the circadian regulation of sleep. Neuron (2015) 0.84
Norepinephrine is required to promote wakefulness and for hypocretin-induced arousal in zebrafish. Elife (2015) 0.81
A New Anaesthetic Protocol for Adult Zebrafish (Danio rerio): Propofol Combined with Lidocaine. PLoS One (2016) 0.81
Neurochemical measurements in the zebrafish brain. Front Behav Neurosci (2015) 0.78
Developmental Deltamethrin Exposure Causes Persistent Changes in Dopaminergic Gene Expression, Neurochemistry, and Locomotor Activity in Zebrafish. Toxicol Sci (2015) 0.77
QRFP and Its Receptors Regulate Locomotor Activity and Sleep in Zebrafish. J Neurosci (2016) 0.77
Leveraging Large-scale Behavioral Profiling in Zebrafish to Explore Neuroactive Polypharmacology. ACS Chem Biol (2016) 0.76
Unraveling the Evolutionary Determinants of Sleep. Curr Biol (2016) 0.76
Function Over Form: Modeling Groups of Inherited Neurological Conditions in Zebrafish. Front Mol Neurosci (2016) 0.76
Genetic Analysis of Histamine Signaling in Larval Zebrafish Sleep. eNeuro (2017) 0.75
Tetramethylenedisulfotetramine: pest control gone awry. Ann N Y Acad Sci (2016) 0.75
Zebrafish models in neuropsychopharmacology and CNS drug discovery. Br J Pharmacol (2017) 0.75
Assessing the value of the zebrafish conditioned place preference model for predicting human abuse potential. J Pharmacol Exp Ther (2017) 0.75
Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index. PLoS Med (2004) 11.17
Narcolepsy with cataplexy. Lancet (2007) 4.81
History of the development of sleep medicine in the United States. J Clin Sleep Med (2005) 4.22
Narcolepsy onset is seasonal and increased following the 2009 H1N1 pandemic in China. Ann Neurol (2011) 4.09
Narcolepsy is strongly associated with the T-cell receptor alpha locus. Nat Genet (2009) 3.33
Post-H1N1 narcolepsy-cataplexy. Sleep (2010) 3.10
Elevated anti-streptococcal antibodies in patients with recent narcolepsy onset. Sleep (2009) 3.06
Kleine-Levin syndrome: a systematic study of 108 patients. Ann Neurol (2008) 3.03
Mapping multiple sclerosis susceptibility to the HLA-DR locus in African Americans. Am J Hum Genet (2003) 2.71
Retracted CD4+ T cell autoimmunity to hypocretin/orexin and cross-reactivity to a 2009 H1N1 influenza A epitope in narcolepsy. Sci Transl Med (2013) 2.51
Characterization of sleep in zebrafish and insomnia in hypocretin receptor mutants. PLoS Biol (2007) 2.34
The role of hypocretins (orexins) in sleep regulation and narcolepsy. Annu Rev Neurosci (2002) 2.28
Genetics of sleep and sleep disorders. Cell (2011) 2.26
Variant between CPT1B and CHKB associated with susceptibility to narcolepsy. Nat Genet (2008) 2.09
Correlates of serum C-reactive protein (CRP)--no association with sleep duration or sleep disordered breathing. Sleep (2007) 1.88
DQB1*0602 predicts interindividual differences in physiologic sleep, sleepiness, and fatigue. Neurology (2010) 1.86
Diagnosis, disease course, and management of patients with Kleine-Levin syndrome. Lancet Neurol (2012) 1.83
The narcoleptic borderland: a multimodal diagnostic approach including cerebrospinal fluid levels of hypocretin-1 (orexin A). Sleep Med (2003) 1.72
A link between short sleep and obesity: building the evidence for causation. Sleep (2005) 1.67
Common variants in P2RY11 are associated with narcolepsy. Nat Genet (2010) 1.65
Clinical and therapeutic aspects of childhood narcolepsy-cataplexy: a retrospective study of 51 children. Sleep (2010) 1.64
Circadian and homeostatic regulation of hypocretin in a primate model: implications for the consolidation of wakefulness. J Neurosci (2003) 1.64
Clinical aspects of narcolepsy-cataplexy across ethnic groups. Sleep (2002) 1.59
ImmunoChip study implicates antigen presentation to T cells in narcolepsy. PLoS Genet (2013) 1.55
PER3 polymorphism predicts cumulative sleep homeostatic but not neurobehavioral changes to chronic partial sleep deprivation. PLoS One (2009) 1.54
parachute/n-cadherin is required for morphogenesis and maintained integrity of the zebrafish neural tube. Development (2002) 1.53
Mutations in DNMT1 cause autosomal dominant cerebellar ataxia, deafness and narcolepsy. Hum Mol Genet (2012) 1.48
Anti-Tribbles homolog 2 (TRIB2) autoantibodies in narcolepsy are associated with recent onset of cataplexy. Sleep (2010) 1.47
Melanopsin as a sleep modulator: circadian gating of the direct effects of light on sleep and altered sleep homeostasis in Opn4(-/-) mice. PLoS Biol (2009) 1.43
8-OH-DPAT acts on both 5-HT1A and 5-HT7 receptors to induce hypothermia in rodents. Eur J Pharmacol (2004) 1.40
Blockade of orexin-1 receptors attenuates orexin-2 receptor antagonism-induced sleep promotion in the rat. J Pharmacol Exp Ther (2009) 1.40
Increased risk of narcolepsy in children and adults after pandemic H1N1 vaccination in France. Brain (2013) 1.39
Complex movement disorders at disease onset in childhood narcolepsy with cataplexy. Brain (2011) 1.35
Circadian and homeostatic regulation of structural synaptic plasticity in hypocretin neurons. Neuron (2010) 1.33
Sleep/wake fragmentation disrupts metabolism in a mouse model of narcolepsy. J Physiol (2007) 1.30
Relationship between CSF hypocretin levels and hypocretin neuronal loss. Exp Neurol (2003) 1.28
Predictors of hypocretin (orexin) deficiency in narcolepsy without cataplexy. Sleep (2012) 1.28
Diurnal variation of cerebrospinal fluid hypocretin-1 (Orexin-A) levels in control and depressed subjects. Biol Psychiatry (2003) 1.27
Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1. PLoS Genet (2011) 1.27
CSF hypocretin-1 assessment in sleep and neurological disorders. Lancet Neurol (2008) 1.24
The diurnal rhythm of hypocretin in young and old F344 rats. Sleep (2004) 1.22
Different periodicity and time structure of leg movements during sleep in narcolepsy/cataplexy and restless legs syndrome. Sleep (2006) 1.19
The genetics of narcolepsy. Annu Rev Genomics Hum Genet (2003) 1.18
The neurobiology of hypocretins (orexins), narcolepsy and related therapeutic interventions. Trends Pharmacol Sci (2006) 1.18
Narcolepsy with hypocretin/orexin deficiency, infections and autoimmunity of the brain. Curr Opin Neurobiol (2011) 1.17
Decreased CSF histamine in narcolepsy with and without low CSF hypocretin-1 in comparison to healthy controls. Sleep (2009) 1.16
CSF versus serum leptin in narcolepsy: is there an effect of hypocretin deficiency? Sleep (2006) 1.15
Body mass index-independent metabolic alterations in narcolepsy with cataplexy. Sleep (2009) 1.13
DQB1*0301 and DQB1*0601 modulate narcolepsy susceptibility in Koreans. Hum Immunol (2006) 1.12
INSL5 is a high affinity specific agonist for GPCR142 (GPR100). J Biol Chem (2004) 1.12
Future of genetics of mood disorders research. Biol Psychiatry (2002) 1.11
IGFBP3 colocalizes with and regulates hypocretin (orexin). PLoS One (2009) 1.11
Cataplexy features in childhood narcolepsy. Mov Disord (2008) 1.11
Regulation of hypocretin (orexin) expression in embryonic zebrafish. J Biol Chem (2006) 1.10
Decreased incidence of childhood narcolepsy 2 years after the 2009 H1N1 winter flu pandemic. Ann Neurol (2012) 1.09
Selective blockade of the orexin-2 receptor attenuates ethanol self-administration, place preference, and reinstatement. Psychopharmacology (Berl) (2010) 1.08
Acute light exposure suppresses circadian rhythms in clock gene expression. J Biol Rhythms (2011) 1.08
Genome wide analysis of narcolepsy in China implicates novel immune loci and reveals changes in association prior to versus after the 2009 H1N1 influenza pandemic. PLoS Genet (2013) 1.08
REM behavior disorder (RBD) can be one of the first symptoms of childhood narcolepsy. Sleep Med (2007) 1.07
Sleep-wake regulation and hypocretin-melatonin interaction in zebrafish. Proc Natl Acad Sci U S A (2009) 1.04
Increase of histaminergic tuberomammillary neurons in narcolepsy. Ann Neurol (2013) 1.04
Daytime continuous polysomnography predicts MSLT results in hypersomnias of central origin. J Sleep Res (2012) 1.04
R3(BDelta23 27)R/I5 chimeric peptide, a selective antagonist for GPCR135 and GPCR142 over relaxin receptor LGR7: in vitro and in vivo characterization. J Biol Chem (2007) 1.03
The autoimmune basis of narcolepsy. Curr Opin Neurobiol (2013) 1.03
Depression: relationships to sleep paralysis and other sleep disturbances in a community sample. J Sleep Res (2007) 1.03
Nocturnal rapid eye movement sleep latency for identifying patients with narcolepsy/hypocretin deficiency. JAMA Neurol (2013) 1.02
Early IVIg treatment has no effect on post-H1N1 narcolepsy phenotype or hypocretin deficiency. Neurology (2012) 1.02
The genetics of sleep disorders. Lancet Neurol (2002) 1.02
Genetic association, seasonal infections and autoimmune basis of narcolepsy. J Autoimmun (2013) 0.99
Narcolepsy with cataplexy associated with holoprosencephaly misdiagnosed as epileptic drop attacks. Mov Disord (2010) 0.98
Distribution of relaxin-3 and RXFP3 within arousal, stress, affective, and cognitive circuits of mouse brain. J Comp Neurol (2010) 0.97
Lesions of the suprachiasmatic nucleus eliminate the daily rhythm of hypocretin-1 release. Sleep (2004) 0.97
Apolipoprotein E and obstructive sleep apnea: evaluating whether a candidate gene explains a linkage peak. Genet Epidemiol (2006) 0.97
Non-circadian direct effects of light on sleep and alertness: lessons from transgenic mouse models. Sleep Med Rev (2013) 0.97
Increased hypocretin-1 (orexin-a) levels in cerebrospinal fluid of rats after short-term forced activity. Regul Pept (2004) 0.96
Report of a case of immunosuppression with prednisone in an 8-year-old boy with an acute onset of hypocretin-deficiency narcolepsy. Sleep (2003) 0.96
Periodic leg movements during sleep are associated with polymorphisms in BTBD9, TOX3/BC034767, MEIS1, MAP2K5/SKOR1, and PTPRD. Sleep (2014) 0.95
Disrupted nighttime sleep in narcolepsy. J Clin Sleep Med (2013) 0.95
Distribution of G-protein-coupled receptor (GPCR)135 binding sites and receptor mRNA in the rat brain suggests a role for relaxin-3 in neuroendocrine and sensory processing. Neuroendocrinology (2005) 0.95
Mechano-sensory organ regeneration in adults: the zebrafish lateral line as a model. Mol Cell Neurosci (2006) 0.95
Intravenous high-dose immunoglobulin treatment in recent onset childhood narcolepsy with cataplexy. J Neurol (2008) 0.95
English translations of the first clinical reports on narcolepsy and cataplexy by Westphal and Gélineau in the late 19th century, with commentary. J Clin Sleep Med (2007) 0.95
Relaxin-3/insulin-like peptide 5 chimeric peptide, a selective ligand for G protein-coupled receptor (GPCR)135 and GPCR142 over leucine-rich repeat-containing G protein-coupled receptor 7. Mol Pharmacol (2004) 0.94
Narcolepsy: genetic predisposition and neuropharmacological mechanisms. REVIEW ARTICLE. Sleep Med Rev (2000) 0.94
Characterization of two melanin-concentrating hormone genes in zebrafish reveals evolutionary and physiological links with the mammalian MCH system. J Comp Neurol (2009) 0.94
Decreased hypocretin-1 (Orexin-A) levels in the cerebrospinal fluid of patients with myotonic dystrophy and excessive daytime sleepiness. Sleep (2003) 0.94
Comparative expression of p2x receptors and ecto-nucleoside triphosphate diphosphohydrolase 3 in hypocretin and sensory neurons in zebrafish. Brain Res (2007) 0.93
Association of sleep disordered breathing and cognitive deficit in APOE ε4 carriers. Sleep (2013) 0.92
The novel, selective, brain-penetrant neuropeptide Y Y2 receptor antagonist, JNJ-31020028, tested in animal models of alcohol consumption, relapse, and anxiety. Alcohol (2010) 0.92
High prevalence of precocious puberty and obesity in childhood narcolepsy with cataplexy. Sleep (2013) 0.92
Complex interaction of circadian and non-circadian effects of light on mood: shedding new light on an old story. Sleep Med Rev (2012) 0.92
Late-onset narcolepsy presenting as rapidly progressing muscle weakness: response to plasmapheresis. Ann Neurol (2005) 0.91