Published in Org Lett on May 17, 2007
Incorporation of heterocycles into the backbone of peptoids to generate diverse peptoid-inspired one bead one compound libraries. ACS Comb Sci (2012) 1.11
Sophistication of foldamer form and function in vitro and in vivo. Curr Opin Chem Biol (2007) 1.11
Probing the bioactive conformation of an archetypal natural product HDAC inhibitor with conformationally homogeneous triazole-modified cyclic tetrapeptides. Angew Chem Int Ed Engl (2009) 1.08
Acyl hydrazides as peptoid sub-monomers. Chem Commun (Camb) (2011) 1.07
Protein prosthesis: 1,5-disubstituted[1,2,3]triazoles as cis-peptide bond surrogates. J Am Chem Soc (2007) 1.04
Construction of peptoids with all trans-amide backbones and peptoid reverse turns via the tactical incorporation of N-aryl side chains capable of hydrogen bonding. J Org Chem (2010) 0.96
Submonomer synthesis of a hybrid peptoid-azapeptoid library. ACS Comb Sci (2012) 0.93
Synthesis of new triazole-based trifluoromethyl scaffolds. Beilstein J Org Chem (2008) 0.81
Close mimicry of lung surfactant protein B by "clicked" dimers of helical, cationic peptoids. Biopolymers (2009) 0.80
1,4-linked 1,2,3-Triazole des-peptidic analogues of PNA (TzNA): Synthesis of TzNA oligomers by "click" reaction on solid phase and stabilization of derived triplexes with DNA. Artif DNA PNA XNA (2010) 0.79
Conformational properties of 1,4- and 1,5-substituted 1,2,3-triazole amino acids – building units for peptidic foldamers. Org Biomol Chem (2015) 0.75
A conserved mechanism for centromeric nucleosome recognition by centromere protein CENP-C. Science (2013) 2.00
Structural basis for recognition of centromere histone variant CenH3 by the chaperone Scm3. Nature (2011) 1.99
Protein folding: defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins. Protein Sci (2005) 1.91
Structure of the Tfb1/p53 complex: Insights into the interaction between the p62/Tfb1 subunit of TFIIH and the activation domain of p53. Mol Cell (2006) 1.82
A protein folding pathway with multiple folding intermediates at atomic resolution. Proc Natl Acad Sci U S A (2005) 1.82
Membrane fusion. Chem Rev (2003) 1.69
Chz1, a nuclear chaperone for histone H2AZ. Mol Cell (2007) 1.64
Relating molecular flexibility to function: a case study of tubulin. Biophys J (2002) 1.62
15N NMR spin relaxation dispersion study of the molecular crowding effects on protein folding under native conditions. J Am Chem Soc (2006) 1.60
Architecture of the high mobility group nucleosomal protein 2-nucleosome complex as revealed by methyl-based NMR. Proc Natl Acad Sci U S A (2011) 1.59
NMR structure of chaperone Chz1 complexed with histones H2A.Z-H2B. Nat Struct Mol Biol (2008) 1.40
Probing the structural requirements of peptoids that inhibit HDM2-p53 interactions. J Am Chem Soc (2006) 1.31
Relationship between the native-state hydrogen exchange and folding pathways of a four-helix bundle protein. Biochemistry (2002) 1.29
Structural basis for p300 Taz2-p53 TAD1 binding and modulation by phosphorylation. Structure (2009) 1.28
Gamma-substituted peptide nucleic acids constructed from L-lysine are a versatile scaffold for multifunctional display. Angew Chem Int Ed Engl (2007) 1.24
Substrate specificity of the human protein phosphatase 2Cdelta, Wip1. Biochemistry (2005) 1.23
Specific non-native hydrophobic interactions in a hidden folding intermediate: implications for protein folding. Biochemistry (2003) 1.22
Positive feedback between p53 and TRF2 during telomere-damage signalling and cellular senescence. Nat Cell Biol (2010) 1.14
Detection of a hidden folding intermediate of the third domain of PDZ. J Mol Biol (2004) 1.13
An exchange-free measure of 15N transverse relaxation: an NMR spectroscopy application to the study of a folding intermediate with pervasive chemical exchange. J Am Chem Soc (2007) 1.11
A model of voltage gating developed using the KvAP channel crystal structure. Biophys J (2004) 1.09
The folding pathway of T4 lysozyme: the high-resolution structure and folding of a hidden intermediate. J Mol Biol (2006) 1.08
Structural insights into the histone H1-nucleosome complex. Proc Natl Acad Sci U S A (2013) 1.08
Programmable multivalent display of receptor ligands using peptide nucleic acid nanoscaffolds. Nat Commun (2012) 1.06
Development of a substrate-based cyclic phosphopeptide inhibitor of protein phosphatase 2Cdelta, Wip1. Biochemistry (2006) 1.06
p53 N-terminal phosphorylation: a defining layer of complex regulation. Carcinogenesis (2012) 1.06
Structural and functional insights into the HIV-1 maturation inhibitor binding pocket. PLoS Pathog (2012) 1.06
Detection and structure determination of an equilibrium unfolding intermediate of Rd-apocytochrome b562: native fold with non-native hydrophobic interactions. J Mol Biol (2004) 1.05
Models of voltage-dependent conformational changes in NaChBac channels. Biophys J (2008) 1.05
The Wip1 phosphatase PPM1D dephosphorylates SQ/TQ motifs in checkpoint substrates phosphorylated by PI3K-like kinases. Biochemistry (2007) 1.04
Redesign of a four-helix bundle protein by phage display coupled with proteolysis and structural characterization by NMR and X-ray crystallography. J Mol Biol (2002) 1.04
Colorimetric detection of anthrax DNA with a Peptide nucleic acid sandwich-hybridization assay. J Am Chem Soc (2007) 1.04
Specificity of acyl transfer from 2-mercaptobenzamide thioesters to the HIV-1 nucleocapsid protein. J Am Chem Soc (2007) 1.03
(S,S)-trans-cyclopentane-constrained peptide nucleic acids. a general backbone modification that improves binding affinity and sequence specificity. J Am Chem Soc (2004) 1.03
Sialylated core 1 O-glycans influence the sorting of Pmel17/gp100 and determine its capacity to form fibrils. J Biol Chem (2007) 1.03
The folding pathway of barnase: the rate-limiting transition state and a hidden intermediate under native conditions. Biochemistry (2004) 1.02
Solution structure of a multifunctional DNA- and protein-binding motif of human Werner syndrome protein. Proc Natl Acad Sci U S A (2005) 1.00
NMR structure of the complex between the Tfb1 subunit of TFIIH and the activation domain of VP16: structural similarities between VP16 and p53. J Am Chem Soc (2008) 0.99
Synthesis of gamma-substituted peptide nucleic acids: a new place to attach fluorophores without affecting DNA binding. Org Lett (2005) 0.98
Unfolding, aggregation, and amyloid formation by the tetramerization domain from mutant p53 associated with lung cancer. Biochemistry (2006) 0.98
An on-pathway hidden intermediate and the early rate-limiting transition state of Rd-apocytochrome b562 characterized by protein engineering. J Mol Biol (2005) 0.98
Models of the structure and gating mechanisms of the pore domain of the NaChBac ion channel. Biophys J (2008) 0.98
Click dimers to target HIV TAR RNA conformation. Biochemistry (2012) 0.97
Small-molecule inactivation of HIV-1 NCp7 by repetitive intracellular acyl transfer. Nat Chem Biol (2010) 0.96
The folding pathway of T4 lysozyme: an on-pathway hidden folding intermediate. J Mol Biol (2006) 0.95
Selective characterization of microsecond motions in proteins by NMR relaxation. J Am Chem Soc (2009) 0.95
N-acylpolyamine inhibitors of HDM2 and HDMX binding to p53. Bioorg Med Chem (2009) 0.95
The high-resolution NMR structure of the early folding intermediate of the Thermus thermophilus ribonuclease H. J Mol Biol (2008) 0.94
Advantages of peptide nucleic acids as diagnostic platforms for detection of nucleic acids in resource-limited settings. J Infect Dis (2010) 0.94
Synthesis and anticancer activities of 6-amino amonafide derivatives. Anticancer Drugs (2008) 0.94
Populating partially unfolded forms by hydrogen exchange-directed protein engineering. Biochemistry (2002) 0.94
Probing the transition state ensemble of a protein folding reaction by pressure-dependent NMR relaxation dispersion. J Am Chem Soc (2006) 0.93
Characterization of the N-terminal tail domain of histone H3 in condensed nucleosome arrays by hydrogen exchange and NMR. J Am Chem Soc (2009) 0.93
Importance of electrostatic interactions in the association of intrinsically disordered histone chaperone Chz1 and histone H2A.Z-H2B. PLoS Comput Biol (2012) 0.92
Detection of a hidden folding intermediate in the focal adhesion target domain: Implications for its function and folding. Proteins (2006) 0.91
Structural biology: analysis of protein-folding cooperativity. Nature (2007) 0.90
Spectroscopic and functional determination of the interaction of Pb2+ with GATA proteins. J Am Chem Soc (2005) 0.89
Optimization of a cyclic peptide inhibitor of Ser/Thr phosphatase PPM1D (Wip1). Biochemistry (2011) 0.89
Topical microbicides: a promising approach for controlling the AIDS pandemic via retroviral zinc finger inhibitors. Adv Pharmacol (2008) 0.89
Structural examination of phi-value analysis in protein folding. Biochemistry (2004) 0.89
Stabilization of G-quadruplex in the BCL2 promoter region in double-stranded DNA by invading short PNAs. Nucleic Acids Res (2009) 0.89
An 15N NMR spin relaxation dispersion study of the folding of a pair of engineered mutants of apocytochrome b562. J Am Chem Soc (2005) 0.89
Methoxyethylamino-numonafide is an efficacious and minimally toxic amonafide derivative in murine models of human cancer. Neoplasia (2011) 0.88
Beta-barrel models of soluble amyloid beta oligomers and annular protofibrils. Proteins (2010) 0.88
Histone H4 K16Q mutation, an acetylation mimic, causes structural disorder of its N-terminal basic patch in the nucleosome. J Mol Biol (2012) 0.88
PNA-DNA duplexes, triplexes, and quadruplexes are stabilized with trans-cyclopentane units. J Am Chem Soc (2006) 0.87
Identification of functionally conserved regions in the structure of the chaperone/CenH3/H4 complex. J Mol Biol (2012) 0.87
Enhanced oligonucleotide binding to self-assembled nanofibers. Bioconjug Chem (2005) 0.86
Recognition of HIV-TAR RNA using neomycin-benzimidazole conjugates. Bioorg Med Chem Lett (2013) 0.85
Structure of the budding yeast Saccharomyces cerevisiae centromeric histones Cse4-H4 complexed with the chaperone Scm3. Proc Natl Acad Sci U S A (2011) 0.84
Nonionic side chains modulate the affinity and specificity of binding between functionalized polyamines and structured RNA. J Am Chem Soc (2004) 0.84
Multivalent binding oligomers inhibit HIV Tat-TAR interaction critical for viral replication. Bioorg Med Chem Lett (2009) 0.84
Targeting DNA G-quadruplex structures with peptide nucleic acids. Curr Pharm Des (2012) 0.84
Design and folding of a multidomain protein. Biochemistry (2005) 0.83
Binding kinetics of histone chaperone Chz1 and variant histone H2A.Z-H2B by relaxation dispersion NMR spectroscopy. J Mol Biol (2009) 0.83
Comparison of the specificity of interaction of cellular and viral zinc-binding domains with 2-mercaptobenzamide thioesters. J Am Chem Soc (2006) 0.83