Published in J Am Chem Soc on June 15, 2007
Using commercially available personal glucose meters for portable quantification of DNA. Anal Chem (2012) 1.03
Advantages of peptide nucleic acids as diagnostic platforms for detection of nucleic acids in resource-limited settings. J Infect Dis (2010) 0.94
Facile SNP detection using bifunctional, cross-linking oligonucleotide probes. Nucleic Acids Res (2008) 0.92
Non-natural nucleic acids for synthetic biology. Curr Opin Chem Biol (2009) 0.86
Sandwich assay for mixed-sequence recognition of double-stranded DNA: invader-based detection of targets specific to foodborne pathogens. Chem Commun (Camb) (2013) 0.83
Sequence-specific nucleic acid detection from binary pore conductance measurement. J Am Chem Soc (2012) 0.81
Inducible alkylation of DNA by a quinone methide-peptide nucleic acid conjugate. Biochemistry (2012) 0.81
Nucleic acid sandwich hybridization assay with quantum dot-induced fluorescence resonance energy transfer for pathogen detection. Sensors (Basel) (2012) 0.79
Cyclopentane-peptide nucleic acids for qualitative, quantitative, and repetitive detection of nucleic acids. Anal Chem (2012) 0.78
Separation of Mycobacterium abscessus into subspecies or genotype level by direct application of peptide nucleic acid multi-probe- real-time PCR method into sputa samples. BMC Infect Dis (2015) 0.76
Development of peptide nucleic acid probes for detection of the HER2 oncogene. PLoS One (2013) 0.75
Quantification of plasma HIV RNA using chemically engineered peptide nucleic acids. Nat Commun (2014) 0.75
Nanopore biosensor for label-free and real-time detection of anthrax lethal factor. ACS Appl Mater Interfaces (2014) 0.75
Probing the structural requirements of peptoids that inhibit HDM2-p53 interactions. J Am Chem Soc (2006) 1.31
Gamma-substituted peptide nucleic acids constructed from L-lysine are a versatile scaffold for multifunctional display. Angew Chem Int Ed Engl (2007) 1.24
Programmable multivalent display of receptor ligands using peptide nucleic acid nanoscaffolds. Nat Commun (2012) 1.06
(S,S)-trans-cyclopentane-constrained peptide nucleic acids. a general backbone modification that improves binding affinity and sequence specificity. J Am Chem Soc (2004) 1.03
Introduction of a triazole amino acid into a peptoid oligomer induces turn formation in aqueous solution. Org Lett (2007) 1.00
Synthesis of gamma-substituted peptide nucleic acids: a new place to attach fluorophores without affecting DNA binding. Org Lett (2005) 0.98
Click dimers to target HIV TAR RNA conformation. Biochemistry (2012) 0.97
Small-molecule inactivation of HIV-1 NCp7 by repetitive intracellular acyl transfer. Nat Chem Biol (2010) 0.96
N-acylpolyamine inhibitors of HDM2 and HDMX binding to p53. Bioorg Med Chem (2009) 0.95
Advantages of peptide nucleic acids as diagnostic platforms for detection of nucleic acids in resource-limited settings. J Infect Dis (2010) 0.94
Synthesis and anticancer activities of 6-amino amonafide derivatives. Anticancer Drugs (2008) 0.94
Stabilization of G-quadruplex in the BCL2 promoter region in double-stranded DNA by invading short PNAs. Nucleic Acids Res (2009) 0.89
Optimization of a cyclic peptide inhibitor of Ser/Thr phosphatase PPM1D (Wip1). Biochemistry (2011) 0.89
Methoxyethylamino-numonafide is an efficacious and minimally toxic amonafide derivative in murine models of human cancer. Neoplasia (2011) 0.88
PNA-DNA duplexes, triplexes, and quadruplexes are stabilized with trans-cyclopentane units. J Am Chem Soc (2006) 0.87
Enhanced oligonucleotide binding to self-assembled nanofibers. Bioconjug Chem (2005) 0.86
Recognition of HIV-TAR RNA using neomycin-benzimidazole conjugates. Bioorg Med Chem Lett (2013) 0.85
Nonionic side chains modulate the affinity and specificity of binding between functionalized polyamines and structured RNA. J Am Chem Soc (2004) 0.84
Multivalent binding oligomers inhibit HIV Tat-TAR interaction critical for viral replication. Bioorg Med Chem Lett (2009) 0.84
Targeting DNA G-quadruplex structures with peptide nucleic acids. Curr Pharm Des (2012) 0.84
Peptide nucleic acids with a flexible secondary amine in the backbone maintain oligonucleotide binding affinity. Org Lett (2004) 0.81
A small molecular scaffold for selective inhibition of Wip1 phosphatase. ChemMedChem (2008) 0.81
Quadruplex formation is necessary for stable PNA invasion into duplex DNA of BCL2 promoter region. Nucleic Acids Res (2011) 0.81
A new family of small molecules to probe the reactivation of mutant p53. J Am Chem Soc (2005) 0.80
Solid-phase synthesis and screening of N-acylated polyamine (NAPA) combinatorial libraries for protein binding. Bioorg Med Chem Lett (2010) 0.80
Programmable nanoscaffolds that control ligand display to a G-protein-coupled receptor in membranes to allow dissection of multivalent effects. J Am Chem Soc (2014) 0.79
Cyclopentane-peptide nucleic acids for qualitative, quantitative, and repetitive detection of nucleic acids. Anal Chem (2012) 0.78
A cyclopentane conformational restraint for a peptide nucleic acid: design, asymmetric synthesis, and improved binding affinity to DNA and RNA. Org Lett (2003) 0.78
Aziridination of aliphatic alkenes catalyzed by N-heterocyclic carbene copper complexes. Org Lett (2008) 0.78
An efficient synthesis of a probe for protein function: 2,3-diaminopropionic acid with orthogonal protecting groups. Org Lett (2004) 0.77
Cyclopentane peptide nucleic acids. Methods Mol Biol (2014) 0.77
PPG peptide nucleic acids that promote DNA guanine quadruplexes. Chembiochem (2014) 0.77
Novel inhibitors of a Grb2 SH3C domain interaction identified by a virtual screen. Bioorg Med Chem (2012) 0.76
Inhibition of multidrug resistance by SV40 pseudovirion delivery of an antigene peptide nucleic acid (PNA) in cultured cells. PLoS One (2011) 0.76
Directed evolution: overcoming biology's limitations. Nat Chem Biol (2010) 0.76
Combinatorial Synthesis, Screening, and Binding Studies of Highly Functionalized Polyamino-amido Oligomers for Binding to Folded RNA. J Nucleic Acids (2012) 0.75
Induction of apoptosis promoted by Bang52; a small molecule that downregulates Bcl-x(L). Bioorg Med Chem Lett (2009) 0.75
G-quadruplex formation between G-rich PNA and homologous sequences in oligonucleotides and supercoiled plasmid DNA. Nucleic Acid Ther (2015) 0.75
A one-pot preparation of N-2-mercaptobenzoyl-amino amides. Tetrahedron Lett (2011) 0.75
Practical synthesis of trans-tert-butyl-2-aminocyclopentylcarbamate and resolution of enantiomers. J Org Chem (2006) 0.75
Mimicking nature: from fundamentals to applications. Curr Opin Chem Biol (2009) 0.75
Cyclopentane-modified PNA improves the sensitivity of nanoparticle-based scanometric DNA detection. Chem Commun (Camb) (2005) 0.75
Peptide nucleic acid microarrays made with (S,S)-trans-cyclopentane-constrained peptide nucleic acids. Methods Enzymol (2006) 0.75