Renoprotective role of the vitamin D receptor in diabetic nephropathy.

PubWeight™: 3.06‹?› | Rank: Top 1%

🔗 View Article (PMID 17928826)

Published in Kidney Int on October 10, 2007

Authors

Z Zhang1, L Sun, Y Wang, G Ning, A W Minto, J Kong, R J Quigg, Y C Li

Author Affiliations

1: Division of Biological Sciences, Department of Medicine, The University of Chicago, Chicago, Illinois, USA.

Articles citing this

Vitamin D and human health: lessons from vitamin D receptor null mice. Endocr Rev (2008) 5.28

MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy. FASEB J (2008) 2.75

Chronic kidney disease, hypovitaminosis D, and mortality in the United States. Kidney Int (2009) 2.52

Combination therapy with AT1 blocker and vitamin D analog markedly ameliorates diabetic nephropathy: blockade of compensatory renin increase. Proc Natl Acad Sci U S A (2008) 2.06

Vitamin D reduces the expression of collagen and key profibrotic factors by inducing an antifibrotic phenotype in mesenchymal multipotent cells. J Endocrinol (2008) 1.72

Plasma 25-hydroxyvitamin D and regulation of the renin-angiotensin system in humans. Hypertension (2010) 1.69

The world pandemic of vitamin D deficiency could possibly be explained by cellular inflammatory response activity induced by the renin-angiotensin system. Am J Physiol Cell Physiol (2013) 1.56

Possible renoprotection by vitamin D in chronic renal disease: beyond mineral metabolism. Nat Rev Nephrol (2009) 1.51

Vitamin D receptor attenuates renal fibrosis by suppressing the renin-angiotensin system. J Am Soc Nephrol (2010) 1.50

1,25-Dihydroxyvitamin D3 suppresses high glucose-induced angiotensinogen expression in kidney cells by blocking the NF-{kappa}B pathway. Am J Physiol Renal Physiol (2009) 1.31

Effect of the monocyte chemoattractant protein-1/CC chemokine receptor 2 system on nephrin expression in streptozotocin-treated mice and human cultured podocytes. Diabetes (2009) 1.25

Low-dose paclitaxel ameliorates fibrosis in the remnant kidney model by down-regulating miR-192. J Pathol (2011) 1.24

Vitamin D and chronic kidney disease. Ethn Dis (2009) 1.20

Vitamin D and kidney disease. Clin J Am Soc Nephrol (2008) 1.16

Long-term therapeutic effect of vitamin D analog doxercalciferol on diabetic nephropathy: strong synergism with AT1 receptor antagonist. Am J Physiol Renal Physiol (2009) 1.13

Potential for vitamin D receptor agonists in the treatment of cardiovascular disease. Br J Pharmacol (2009) 1.13

Podocytopathy in diabetes: a metabolic and endocrine disorder. Am J Kidney Dis (2011) 1.10

Therapeutic effects of vitamin D analogs on cardiac hypertrophy in spontaneously hypertensive rats. Am J Pathol (2010) 1.09

Vitamin D and diabetes: let the sunshine in. Diabetes Educ (2008) 1.05

Oral supplementation with cholecalciferol 800 IU ameliorates albuminuria in Chinese type 2 diabetic patients with nephropathy. PLoS One (2012) 1.02

Kidney aging--inevitable or preventable? Nat Rev Nephrol (2011) 0.99

Vitamin D: roles in renal and cardiovascular protection. Curr Opin Nephrol Hypertens (2012) 0.99

Vitamin D receptor signaling in podocytes protects against diabetic nephropathy. J Am Soc Nephrol (2012) 0.98

Vitamin D receptor signaling inhibits atherosclerosis in mice. Mol Endocrinol (2012) 0.97

Serum vitamin D levels are not predictive of the progression of chronic liver disease in hepatitis C patients with advanced fibrosis. PLoS One (2012) 0.93

Vitamin D receptor agonist doxercalciferol modulates dietary fat-induced renal disease and renal lipid metabolism. Am J Physiol Renal Physiol (2011) 0.92

Pathogenesis and novel treatment from the mouse model of type 2 diabetic nephropathy. ScientificWorldJournal (2013) 0.92

Uric acid suppresses 1 alpha hydroxylase in vitro and in vivo. Metabolism (2013) 0.92

Rap1 ameliorates renal tubular injury in diabetic nephropathy. Diabetes (2013) 0.92

Can vitamin D slow down the progression of chronic kidney disease? Pediatr Nephrol (2011) 0.90

Renin-angiotensin system activity in vitamin D deficient, obese individuals with hypertension: An urban Indian study. Indian J Endocrinol Metab (2011) 0.89

Chronic kidney disease: a new look at pathogenetic mechanisms and treatment options. Pediatr Nephrol (2013) 0.88

Role of vitamin d in cardiometabolic diseases. J Diabetes Res (2013) 0.88

Renoprotection with vitamin D: specific for diabetic nephropathy? Kidney Int (2008) 0.87

Nuclear hormone receptors in diabetic nephropathy. Nat Rev Nephrol (2010) 0.86

Whether vitamin D3 is effective in reducing proteinuria in type 2 diabetic patients? J Res Med Sci (2013) 0.86

Molecular mechanism underlying 1,25-dihydroxyvitamin D regulation of nephrin gene expression. J Biol Chem (2011) 0.85

VDR attenuates acute lung injury by blocking Ang-2-Tie-2 pathway and renin-angiotensin system. Mol Endocrinol (2013) 0.85

Lower levels of 25-hydroxyvitamin D3 are associated with a higher prevalence of microvascular complications in patients with type 2 diabetes. BMJ Open Diabetes Res Care (2015) 0.85

Combined losartan and nitro-oleic acid remarkably improves diabetic nephropathy in mice. Am J Physiol Renal Physiol (2013) 0.84

The impact of pretransplant 25-hydroxy vitamin D deficiency on subsequent graft function: an observational study. BMC Nephrol (2012) 0.84

Impact of vitamin D on chronic kidney diseases in non-dialysis patients: a meta-analysis of randomized controlled trials. PLoS One (2013) 0.84

Nuclear receptors in renal disease. Biochim Biophys Acta (2011) 0.84

Twenty years after ACEIs and ARBs: emerging treatment strategies for diabetic nephropathy. Am J Physiol Renal Physiol (2015) 0.83

Calcitriol, calcidiol, parathyroid hormone, and fibroblast growth factor-23 interactions in chronic kidney disease. J Vet Emerg Crit Care (San Antonio) (2013) 0.83

Analysis of the associations between vitamin D and albuminuria or β-cell function in Chinese type 2 diabetes. Biomed Res Int (2014) 0.82

The effects of vitamin d on gentamicin-induced acute kidney injury in experimental rat model. Int J Endocrinol (2013) 0.81

Vitamin D receptor signaling in renal and cardiovascular protection. Semin Nephrol (2013) 0.81

Plasma Vitamin D Level and Change in Albuminuria and eGFR According to Sodium Intake. Clin J Am Soc Nephrol (2015) 0.80

Elevated serum 1,25(OH)2-vitamin D3 level attenuates renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction in kl/kl mice. Sci Rep (2014) 0.80

Loss of vitamin D receptor produces polyuria by increasing thirst. J Am Soc Nephrol (2008) 0.80

A commentary on the VITAL study: Does vitamin D (receptor activation) protect against nephropathy in type 2 diabetes? J Diabetes Investig (2012) 0.79

Diabetes: Effect of vitamin D on diabetic kidney disease in T1DM. Nat Rev Endocrinol (2012) 0.78

The effect of calcium with or without calcitriol supplementation on renal function in patients with hypovitaminosis d and chronic kidney disease. Nephrourol Mon (2014) 0.78

Paricalcitol for secondary hyperparathyroidism in renal transplantation. J Am Soc Nephrol (2014) 0.78

Vitamin D & its analogues in type 2 diabetic nephropathy: a systematic review. J Diabetes Metab Disord (2015) 0.78

Vitamin D and Diabetic Complications: True or False Prophet? Diabetes Ther (2016) 0.78

Nuclear hormone receptors in podocytes. Cell Biosci (2012) 0.77

Effect of vitamin-D analogue on albuminuria in patients with non-dialysed chronic kidney disease stage 4-5: a retrospective single center study. BMC Nephrol (2012) 0.77

RIPK3-Mediated Necroptosis and Apoptosis Contributes to Renal Tubular Cell Progressive Loss and Chronic Kidney Disease Progression in Rats. PLoS One (2016) 0.76

Pharmacologic targets and peritoneal membrane remodeling. Perit Dial Int (2014) 0.76

1,25-dihydroxyvitamin D(3) inhibits podocyte uPAR expression and reduces proteinuria. PLoS One (2013) 0.76

Potential role of vitamin D deficiency on Fabry cardiomyopathy. J Inherit Metab Dis (2013) 0.75

Vitamin D on Early Stages of Diabetic Kidney Disease: A Cross-sectional Study in Patients with Type 1 Diabetes Mellitus. Front Endocrinol (Lausanne) (2016) 0.75

Effect of vitamin D on proteinuria in type 2 diabetic patients. J Nephropathol (2016) 0.75

Vitamin D therapy in diabetic kidney disease. J Nephropharmacol (2014) 0.75

Vitamin D deficiency and related risk factors in patients with diabetic nephropathy. J Int Med Res (2016) 0.75

Involvement of the NLRC4-Inflammasome in Diabetic Nephropathy. PLoS One (2016) 0.75

Analysis of Adequacy of 25-Hydroxi vitamin D3 Supplementation in Patients on Hemodialysis and Parathormone, Calcium and Phosphorus Level in the Blood of These Patients. Mater Sociomed (2015) 0.75

Vitamin D Receptor Deficit Induces Activation of Renin Angiotensin System Via SIRT1 Modulation in Podocytes. Exp Mol Pathol (2017) 0.75

Diabetic nephropathy: What does the future hold? Int Urol Nephrol (2015) 0.75

The use of vitamin D analogues in chronic kidney diseases: possible mechanisms beyond bone and mineral metabolism. NDT Plus (2009) 0.75

Probucol ameliorates renal injury in diabetic nephropathy by inhibiting the expression of the redox enzyme p66Shc. Redox Biol (2017) 0.75

Current evidence on vitamin D deficiency and kidney transplant: What's new? Rev Endocr Metab Disord (2017) 0.75

Vitamin D3 ameliorates podocyte injury through the nephrin signalling pathway. J Cell Mol Med (2017) 0.75

Astragaloside IV protects against podocyte injury via SERCA2-dependent ER stress reduction and AMPKα-regulated autophagy induction in streptozotocin-induced diabetic nephropathy. Sci Rep (2017) 0.75

ISN Forefronts Symposium 2015: Nuclear Receptors and Diabetic Nephropathy. KI Rep (2016) 0.75

The cellular selection between apoptosis and autophagy: roles of vitamin D, glucose and immune response in diabetic nephropathy. Endocrine (2017) 0.75

Articles by these authors

(truncated to the top 100)

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature (2002) 28.79

Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials. Lancet (2005) 24.57

Gene transfer into mouse lyoma cells by electroporation in high electric fields. EMBO J (1982) 17.98

Complete genome sequence of Neisseria meningitidis serogroup B strain MC58. Science (2000) 16.04

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability. Science (1995) 13.15

Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics. J Bacteriol (1997) 12.21

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol Cell (1998) 11.54

Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials. Lancet (2011) 9.20

The relationship between glucose and incident cardiovascular events. A metaregression analysis of published data from 20 studies of 95,783 individuals followed for 12.4 years. Diabetes Care (1999) 9.16

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis. Cancer Res (1994) 9.00

Coronary-artery calcification in young adults with end-stage renal disease who are undergoing dialysis. N Engl J Med (2000) 8.47

The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol. Cell (1996) 8.25

Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 22 randomised trials. Lancet (2014) 8.04

Positional cloning of the gene for multiple endocrine neoplasia-type 1. Science (1997) 7.95

The frequency of chimeric molecules as a consequence of PCR co-amplification of 16S rRNA genes from different bacterial species. Microbiology (1996) 7.78

Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate. Neuron (1996) 7.20

Frequency of formation of chimeric molecules as a consequence of PCR coamplification of 16S rRNA genes from mixed bacterial genomes. Appl Environ Microbiol (1997) 7.09

A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature (1996) 7.04

Statistical tests for detection of misspecified relationships by use of genome-screen data. Am J Hum Genet (2000) 6.96

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks. Science (1999) 6.93

TFAR19, a novel apoptosis-related gene cloned from human leukemia cell line TF-1, could enhance apoptosis of some tumor cells induced by growth factor withdrawal. Biochem Biophys Res Commun (1999) 6.33

Effects of prenatal and postnatal methylmercury exposure from fish consumption on neurodevelopment: outcomes at 66 months of age in the Seychelles Child Development Study. JAMA (1998) 6.30

Readmission after hospitalization for congestive heart failure among Medicare beneficiaries. Arch Intern Med (1997) 5.93

A cluster of hydrophobic amino acid residues required for fast Na(+)-channel inactivation. Proc Natl Acad Sci U S A (1992) 5.60

Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA. Chem Biol (1997) 5.49

Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice. Science (1992) 5.46

Blood transfusion in elderly patients with acute myocardial infarction. N Engl J Med (2001) 5.43

IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs. Cancer Res (1998) 5.41

Genetic diversity and disease control in rice. Nature (2000) 5.34

A role for the lissencephaly gene LIS1 in mitosis and cytoplasmic dynein function. Nat Cell Biol (2000) 5.29

Racial differences in the use of cardiac catheterization after acute myocardial infarction. N Engl J Med (2001) 5.29

Organizing principles for a diversity of GABAergic interneurons and synapses in the neocortex. Science (2000) 5.27

Podocyte loss and progressive glomerular injury in type II diabetes. J Clin Invest (1997) 4.83

Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors. Science (1997) 4.70

Differential signaling via the same axon of neocortical pyramidal neurons. Proc Natl Acad Sci U S A (1998) 4.59

POWER_SAGE: comparing statistical tests for SAGE experiments. Bioinformatics (2000) 4.56

BACE1 is the major beta-secretase for generation of Abeta peptides by neurons. Nat Neurosci (2001) 4.54

Graphene as a subnanometre trans-electrode membrane. Nature (2010) 4.45

Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance. Proc Natl Acad Sci U S A (1996) 4.45

SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling. Mol Cell Biol (2000) 4.30

Do "America's Best Hospitals" perform better for acute myocardial infarction? N Engl J Med (1999) 4.30

SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types. Cancer Res (1999) 4.23

Fringe is a glycosyltransferase that modifies Notch. Nature (2000) 4.09

Broadly protective vaccine for Staphylococcus aureus based on an in vivo-expressed antigen. Science (1999) 4.08

Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation. Immunity (1996) 3.91

Transmissibility of Pseudomonas cepacia infection in clinic patients and lung-transplant recipients with cystic fibrosis. N Engl J Med (1994) 3.89

Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing. Proc Natl Acad Sci U S A (1994) 3.85

Rapid and highly efficient transduction by double-stranded adeno-associated virus vectors in vitro and in vivo. Gene Ther (2003) 3.85

Pleiotropic defects in ataxia-telangiectasia protein-deficient mice. Proc Natl Acad Sci U S A (1996) 3.78

Follicle stimulating hormone is required for ovarian follicle maturation but not male fertility. Nat Genet (1997) 3.69

The presynaptic particle web: ultrastructure, composition, dissolution, and reconstitution. Neuron (2001) 3.68

Signal timing across the macaque visual system. J Neurophysiol (1998) 3.66

The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development. Proc Natl Acad Sci U S A (2000) 3.55

A Myb-related transcription factor is involved in the phytochrome regulation of an Arabidopsis Lhcb gene. Plant Cell (1997) 3.54

The alternative oxidase lowers mitochondrial reactive oxygen production in plant cells. Proc Natl Acad Sci U S A (1999) 3.53

Mutations in SCN9A, encoding a sodium channel alpha subunit, in patients with primary erythermalgia. J Med Genet (2004) 3.45

The ica locus of Staphylococcus epidermidis encodes production of the capsular polysaccharide/adhesin. Infect Immun (1998) 3.44

Cooperative interaction of S. pombe proteins required for mating and morphogenesis. Cell (1994) 3.41

Focal adhesion kinase is involved in mechanosensing during fibroblast migration. Proc Natl Acad Sci U S A (2001) 3.41

A family of mammalian Na+-dependent L-ascorbic acid transporters. Nature (1999) 3.40

Midzone microtubule bundles are continuously required for cytokinesis in cultured epithelial cells. J Cell Biol (1996) 3.36

Criteria and recommendations for vitamin C intake. JAMA (1999) 3.32

Non-Alu family interspersed repeats in human DNA and their transcriptional activity. Nucleic Acids Res (1984) 3.30

Wildtype Kras2 can inhibit lung carcinogenesis in mice. Nat Genet (2001) 3.27

Male fertility potential in terms of semen quality: a review of the past, a study of the present. Fertil Steril (1979) 3.19

Formation of protein kinase recognition sites by covalent modification of the substrate. Molecular mechanism for the synergistic action of casein kinase II and glycogen synthase kinase 3. J Biol Chem (1987) 3.19

The rate-pressure product as an index of myocardial oxygen consumption during exercise in patients with angina pectoris. Circulation (1978) 3.19

Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains. Proc Natl Acad Sci U S A (1996) 3.17

Regulated chromosomal DNA replication in the absence of a nucleus. Mol Cell (1998) 3.11

Identification of toxicants in cinnamon-flavored electronic cigarette refill fluids. Toxicol In Vitro (2014) 3.10

Enhanced Galphaq signaling: a common pathway mediates cardiac hypertrophy and apoptotic heart failure. Proc Natl Acad Sci U S A (1998) 3.05

Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies. Protein Sci (2000) 3.00

Changes in reliability of synaptic function as a mechanism for plasticity. Nature (1994) 2.97

Protective mucosal immunity elicited by targeted iliac lymph node immunization with a subunit SIV envelope and core vaccine in macaques. Nat Med (1996) 2.96

Facilitation and depression at single central synapses. Neuron (1995) 2.95

Mammalian hepatocyte differentiation requires the transcription factor HNF-4alpha. Genes Dev (2000) 2.93

Vam3p structure reveals conserved and divergent properties of syntaxins. Nat Struct Biol (2001) 2.92

Effectiveness of laser therapy and topical desensitising agents in treating dentine hypersensitivity: a systematic review. J Oral Rehabil (2011) 2.91

Antigens displayed on murine B lymphocyte precursors. J Immunol (1981) 2.91

Overview of the randomized trials of radiotherapy in ductal carcinoma in situ of the breast. J Natl Cancer Inst Monogr (2010) 2.91

A member of the Frizzled protein family mediating axis induction by Wnt-5A. Science (1997) 2.90

Stable histone deacetylase complexes distinguished by the presence of SANT domain proteins CoREST/kiaa0071 and Mta-L1. J Biol Chem (2000) 2.89

Multiple independent loci within the human cytomegalovirus unique short region down-regulate expression of major histocompatibility complex class I heavy chains. J Virol (1995) 2.87

Dendrimer-encapsulated metal nanoparticles: synthesis, characterization, and applications to catalysis. Acc Chem Res (2001) 2.85

Expression of Light-Harvesting Chlorophyll a/b-Protein Genes Is Phytochrome-Regulated in Etiolated Arabidopsis thaliana Seedlings. Plant Physiol (1988) 2.85

Coronectomy vs. total removal for third molar extraction: a systematic review. J Dent Res (2012) 2.84

Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency. J Control Release (2001) 2.84

Kinetochore localisation and phosphorylation of the mitotic checkpoint components Bub1 and BubR1 are differentially regulated by spindle events in human cells. J Cell Sci (2001) 2.76

Dentinogenesis imperfecta 1 with or without progressive hearing loss is associated with distinct mutations in DSPP. Nat Genet (2001) 2.75

Distinct types of rRNA operons exist in the genome of the actinomycete Thermomonospora chromogena and evidence for horizontal transfer of an entire rRNA operon. J Bacteriol (1999) 2.72

Aiolos, a lymphoid restricted transcription factor that interacts with Ikaros to regulate lymphocyte differentiation. EMBO J (1997) 2.71

Predictors of readmission among elderly survivors of admission with heart failure. Am Heart J (2000) 2.71

National use and effectiveness of beta-blockers for the treatment of elderly patients after acute myocardial infarction: National Cooperative Cardiovascular Project. JAMA (1998) 2.70

RANTES and monocyte chemoattractant protein-1 (MCP-1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP-1 is involved in crescent formation and interstitial fibrosis. J Exp Med (1997) 2.69

A novel putative low-affinity insulin-like growth factor-binding protein, LIBC (lost in inflammatory breast cancer), and RhoC GTPase correlate with the inflammatory breast cancer phenotype. Clin Cancer Res (1999) 2.69

Regulatory CD4(+) T cells expressing endogenous T cell receptor chains protect myelin basic protein-specific transgenic mice from spontaneous autoimmune encephalomyelitis. J Exp Med (1998) 2.69

Feasibility of a high-speed gamma-camera design using the high-yield-pileup-event-recovery method. J Nucl Med (2001) 2.69

A high-affinity iron permease essential for Candida albicans virulence. Science (2000) 2.68

Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy. Cell (1999) 2.68

Crystallographic comparison of the estrogen and progesterone receptor's ligand binding domains. Proc Natl Acad Sci U S A (1998) 2.68