PubRank

Lance C Seefeldt

Author PubWeight™ 63.18‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Climbing nitrogenase: toward a mechanism of enzymatic nitrogen fixation. Acc Chem Res 2009 2.43
2 Substrate interactions with the nitrogenase active site. Acc Chem Res 2005 2.27
3 Testing if the interstitial atom, X, of the nitrogenase molybdenum-iron cofactor is N or C: ENDOR, ESEEM, and DFT studies of the S = 3/2 resting state in multiple environments. Inorg Chem 2007 2.12
4 Trapping H- bound to the nitrogenase FeMo-cofactor active site during H2 evolution: characterization by ENDOR spectroscopy. J Am Chem Soc 2005 1.93
5 An organometallic intermediate during alkyne reduction by nitrogenase. J Am Chem Soc 2004 1.89
6 Frontiers, opportunities, and challenges in biochemical and chemical catalysis of CO2 fixation. Chem Rev 2013 1.86
7 Mechanism of nitrogen fixation by nitrogenase: the next stage. Chem Rev 2014 1.83
8 Connecting nitrogenase intermediates with the kinetic scheme for N2 reduction by a relaxation protocol and identification of the N2 binding state. Proc Natl Acad Sci U S A 2007 1.79
9 Intermediates trapped during nitrogenase reduction of N triple bond N, CH3-N=NH, and H2N-NH2. J Am Chem Soc 2005 1.68
10 Nitrogen fixation: the mechanism of the Mo-dependent nitrogenase. Crit Rev Biochem Mol Biol 2003 1.65
11 Nitrogenase: a draft mechanism. Acc Chem Res 2013 1.64
12 Trapping a hydrazine reduction intermediate on the nitrogenase active site. Biochemistry 2005 1.44
13 Substrate interaction at an iron-sulfur face of the FeMo-cofactor during nitrogenase catalysis. J Biol Chem 2004 1.40
14 Localization of a substrate binding site on the FeMo-cofactor in nitrogenase: trapping propargyl alcohol with an alpha-70-substituted MoFe protein. Biochemistry 2003 1.37
15 Is Mo involved in hydride binding by the four-electron reduced (E4) intermediate of the nitrogenase MoFe protein? J Am Chem Soc 2010 1.33
16 Diazene (HN=NH) is a substrate for nitrogenase: insights into the pathway of N2 reduction. Biochemistry 2007 1.29
17 A methyldiazene (HN=N-CH3)-derived species bound to the nitrogenase active-site FeMo cofactor: Implications for mechanism. Proc Natl Acad Sci U S A 2006 1.28
18 Molybdenum nitrogenase catalyzes the reduction and coupling of CO to form hydrocarbons. J Biol Chem 2011 1.20
19 Breaking the N2 triple bond: insights into the nitrogenase mechanism. Dalton Trans 2006 1.20
20 57Fe ENDOR spectroscopy and 'electron inventory' analysis of the nitrogenase E4 intermediate suggest the metal-ion core of FeMo-cofactor cycles through only one redox couple. J Am Chem Soc 2011 1.20
21 Localization of a catalytic intermediate bound to the FeMo-cofactor of nitrogenase. J Biol Chem 2004 1.20
22 Trapping an intermediate of dinitrogen (N2) reduction on nitrogenase. Biochemistry 2009 1.20
23 ENDOR/HYSCORE studies of the common intermediate trapped during nitrogenase reduction of N2H2, CH3N2H, and N2H4 support an alternating reaction pathway for N2 reduction. J Am Chem Soc 2011 1.19
24 Alkyne substrate interaction within the nitrogenase MoFe protein. J Inorg Biochem 2007 1.18
25 MECHANISTIC FEATURES OF THE MO-CONTAINING NITROGENASE. Annu Rev Plant Physiol Plant Mol Biol 2001 1.17
26 Characterization of a fatty acyl-CoA reductase from Marinobacter aquaeolei VT8: a bacterial enzyme catalyzing the reduction of fatty acyl-CoA to fatty alcohol. Biochemistry 2011 1.15
27 Biodiesel production by simultaneous extraction and conversion of total lipids from microalgae, cyanobacteria, and wild mixed-cultures. Bioresour Technol 2010 1.13
28 Carbon dioxide reduction to methane and coupling with acetylene to form propylene catalyzed by remodeled nitrogenase. Proc Natl Acad Sci U S A 2012 1.06
29 Conformational gating of electron transfer from the nitrogenase Fe protein to MoFe protein. J Am Chem Soc 2010 1.06
30 Differences in substrate specificities of five bacterial wax ester synthases. Appl Environ Microbiol 2012 1.05
31 On reversible H2 loss upon N2 binding to FeMo-cofactor of nitrogenase. Proc Natl Acad Sci U S A 2013 1.05
32 The interstitial atom of the nitrogenase FeMo-cofactor: ENDOR and ESEEM show it is not an exchangeable nitrogen. J Am Chem Soc 2003 1.04
33 Crystal structure of the L protein of Rhodobacter sphaeroides light-independent protochlorophyllide reductase with MgADP bound: a homologue of the nitrogenase Fe protein. Biochemistry 2008 1.03
34 The interstitial atom of the nitrogenase FeMo-cofactor: ENDOR and ESEEM evidence that it is not a nitrogen. J Am Chem Soc 2005 1.02
35 Purification, characterization, and potential bacterial wax production role of an NADPH-dependent fatty aldehyde reductase from Marinobacter aquaeolei VT8. Appl Environ Microbiol 2009 1.01
36 Insights into substrate binding at FeMo-cofactor in nitrogenase from the structure of an alpha-70(Ile) MoFe protein variant. J Inorg Biochem 2009 1.00
37 Electron transfer within nitrogenase: evidence for a deficit-spending mechanism. Biochemistry 2011 0.98
38 A substrate channel in the nitrogenase MoFe protein. J Biol Inorg Chem 2009 0.96
39 Unification of reaction pathway and kinetic scheme for N2 reduction catalyzed by nitrogenase. Proc Natl Acad Sci U S A 2012 0.95
40 A confirmation of the quench-cryoannealing relaxation protocol for identifying reduction states of freeze-trapped nitrogenase intermediates. Inorg Chem 2014 0.94
41 Uncoupling nitrogenase: catalytic reduction of hydrazine to ammonia by a MoFe protein in the absence of Fe protein-ATP. J Am Chem Soc 2010 0.94
42 A conformational mimic of the MgATP-bound "on state" of the nitrogenase iron protein. Biochemistry 2004 0.92
43 Steric control of the Hi-CO MoFe nitrogenase complex revealed by stopped-flow infrared spectroscopy. Angew Chem Int Ed Engl 2011 0.89
44 EXAFS and NRVS reveal a conformational distortion of the FeMo-cofactor in the MoFe nitrogenase propargyl alcohol complex. J Inorg Biochem 2012 0.89
45 Electron transfer precedes ATP hydrolysis during nitrogenase catalysis. Proc Natl Acad Sci U S A 2013 0.86
46 Insights into the role of nucleotide-dependent conformational change in nitrogenase catalysis: Structural characterization of the nitrogenase Fe protein Leu127 deletion variant with bound MgATP. J Inorg Biochem 2006 0.83
47 Probing the MgATP-bound conformation of the nitrogenase Fe protein by solution small-angle X-ray scattering. Biochemistry 2007 0.82
48 Structural and biochemical implications of single amino acid substitutions in the nucleotide-dependent switch regions of the nitrogenase Fe protein from Azotobacter vinelandii. J Biol Inorg Chem 2004 0.81
49 Substrate channel in nitrogenase revealed by a molecular dynamics approach. Biochemistry 2014 0.80
50 Nitrite and hydroxylamine as nitrogenase substrates: mechanistic implications for the pathway of N₂ reduction. J Am Chem Soc 2014 0.80
51 Temperature invariance of the nitrogenase electron transfer mechanism. Biochemistry 2012 0.79
52 Elucidating thermodynamic parameters for electron transfer proteins using isothermal titration calorimetry: application to the nitrogenase Fe protein. J Biol Inorg Chem 2003 0.77
53 Mechanism of Mo-dependent nitrogenase. Methods Mol Biol 2011 0.76
54 The nitrogenase regulatory enzyme dinitrogenase reductase ADP-ribosyltransferase (DraT) is activated by direct interaction with the signal transduction protein GlnB. J Bacteriol 2012 0.76
55 Correction to temperature invariance of the nitrogenase electron transfer mechanism. Biochemistry 2012 0.75
56 Electron paramagnetic resonance spectroscopy. Methods Mol Biol 2011 0.75
57 Establishing a Thermodynamic Landscape for the Active Site of Mo-Dependent Nitrogenase. J Am Chem Soc 2019 0.75