Published in Antioxid Redox Signal on July 01, 2007
Radical-free biology of oxidative stress. Am J Physiol Cell Physiol (2008) 4.33
Nonequilibrium thermodynamics of thiol/disulfide redox systems: a perspective on redox systems biology. Free Radic Biol Med (2007) 2.47
Redox compartmentalization in eukaryotic cells. Biochim Biophys Acta (2008) 2.35
Redox compartmentalization and cellular stress. Diabetes Obes Metab (2010) 1.27
Redox control systems in the nucleus: mechanisms and functions. Antioxid Redox Signal (2010) 1.25
The depletion of nuclear glutathione impairs cell proliferation in 3t3 fibroblasts. PLoS One (2009) 1.06
Protein Cysteines Map to Functional Networks According to Steady-state Level of Oxidation. J Proteomics Bioinform (2011) 1.04
A nuclear-localized fluorescent hydrogen peroxide probe for monitoring sirtuin-mediated oxidative stress responses in vivo. Chem Biol (2011) 1.01
The cysteine proteome. Free Radic Biol Med (2015) 1.00
Selective targeting of the cysteine proteome by thioredoxin and glutathione redox systems. Mol Cell Proteomics (2013) 0.93
Annexin A2: the importance of being redox sensitive. Int J Mol Sci (2013) 0.86
Increased nuclear thioredoxin-1 potentiates cadmium-induced cytotoxicity. Toxicol Sci (2012) 0.85
Oxidation of survival factor MEF2D in neuronal death and Parkinson's disease. Antioxid Redox Signal (2014) 0.83
Transactivation of gene expression by NF-κB is dependent on thioredoxin reductase activity. Free Radic Biol Med (2011) 0.78
Hydrogen peroxide and central redox theory for aerobic life: A tribute to Helmut Sies: Scout, trailblazer, and redox pioneer. Arch Biochem Biophys (2016) 0.75
Systemic remodeling of the redox regulatory network due to RNAi perturbations of glutaredoxin 1, thioredoxin 1, and glucose-6-phosphate dehydrogenase. BMC Syst Biol (2011) 0.75
Using Sensors and Generators of H2O2 to Elucidate the Toxicity Mechanism of Piperlongumine and Phenethyl Isothiocyanate. Antioxid Redox Signal (2016) 0.75
Exposure Memory and Lung Regeneration. Ann Am Thorac Soc (2016) 0.75
Mediators of endoplasmic reticulum stress-induced apoptosis. EMBO Rep (2006) 8.16
The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore. Nature (2004) 5.85
Cellular stress responses: cell survival and cell death. Int J Cell Biol (2010) 2.74
Nuclear and mitochondrial compartmentation of oxidative stress and redox signaling. Annu Rev Pharmacol Toxicol (2006) 2.48
Nonequilibrium thermodynamics of thiol/disulfide redox systems: a perspective on redox systems biology. Free Radic Biol Med (2007) 2.47
Extracellular thiols and thiol/disulfide redox in metabolism. Annu Rev Nutr (2004) 2.41
The eIF2α kinases: their structures and functions. Cell Mol Life Sci (2013) 2.37
Redox compartmentalization in eukaryotic cells. Biochim Biophys Acta (2008) 2.35
Caspase-12 and ER-stress-mediated apoptosis: the story so far. Ann N Y Acad Sci (2003) 2.26
Loss of total and visceral adipose tissue mass predicts decreases in oxidative stress after weight-loss surgery. Obesity (Silver Spring) (2008) 2.23
Redox potential of human thioredoxin 1 and identification of a second dithiol/disulfide motif. J Biol Chem (2003) 2.14
Compartmentation of Nrf-2 redox control: regulation of cytoplasmic activation by glutathione and DNA binding by thioredoxin-1. Toxicol Sci (2004) 2.12
Association between novel oxidative stress markers and C-reactive protein among adults without clinical coronary heart disease. Atherosclerosis (2005) 2.02
Bcl-2 family on guard at the ER. Am J Physiol Cell Physiol (2009) 1.99
apLCMS--adaptive processing of high-resolution LC/MS data. Bioinformatics (2009) 1.98
Cysteine/cystine couple is a newly recognized node in the circuitry for biologic redox signaling and control. FASEB J (2004) 1.97
TRAIL receptor signalling and modulation: Are we on the right TRAIL? Cancer Treat Rev (2008) 1.94
Trophic and cytoprotective nutrition for intestinal adaptation, mucosal repair, and barrier function. Annu Rev Nutr (2003) 1.93
Targeting the endoplasmic reticulum-stress response as an anticancer strategy. Eur J Pharmacol (2009) 1.92
Intracellular proatherogenic events and cell adhesion modulated by extracellular thiol/disulfide redox state. Circulation (2005) 1.90
Commensal bacteria modulate cullin-dependent signaling via generation of reactive oxygen species. EMBO J (2007) 1.86
Oxidation of glutathione and cysteine in human plasma associated with smoking. Free Radic Biol Med (2003) 1.82
Losing heart: the role of apoptosis in heart disease--a novel therapeutic target? FASEB J (2002) 1.81
Compartmental oxidation of thiol-disulphide redox couples during epidermal growth factor signalling. Biochem J (2005) 1.78
Oxidative stress markers are associated with persistent atrial fibrillation. Clin Chem (2007) 1.72
ER stress contributes to ischemia-induced cardiomyocyte apoptosis. Biochem Biophys Res Commun (2006) 1.68
Unfolded proteins and endoplasmic reticulum stress in neurodegenerative disorders. J Cell Mol Med (2011) 1.68
Diurnal variation in glutathione and cysteine redox states in human plasma. Am J Clin Nutr (2007) 1.66
The role of plasma aminothiols in the prediction of coronary microvascular dysfunction and plaque vulnerability. Atherosclerosis (2011) 1.62
A small molecule inhibits and misdirects assembly of hepatitis B virus capsids. J Virol (2002) 1.61
xMSanalyzer: automated pipeline for improved feature detection and downstream analysis of large-scale, non-targeted metabolomics data. BMC Bioinformatics (2013) 1.61
The relationship between plasma levels of oxidized and reduced thiols and early atherosclerosis in healthy adults. J Am Coll Cardiol (2006) 1.59
Statin therapy for the prevention of atrial fibrillation trial (SToP AF trial). J Cardiovasc Electrophysiol (2010) 1.57
Are plasma citrulline and glutamine biomarkers of intestinal absorptive function in patients with short bowel syndrome? JPEN J Parenter Enteral Nutr (2007) 1.55
Stress management at the ER: regulators of ER stress-induced apoptosis. Pharmacol Ther (2012) 1.52
Extracellular thiol/disulfide redox state affects proliferation rate in a human colon carcinoma (Caco2) cell line. Free Radic Biol Med (2002) 1.51
Thioredoxin and its role in toxicology. Toxicol Sci (2003) 1.48
The redox proteome. J Biol Chem (2013) 1.48
EF24, a novel synthetic curcumin analog, induces apoptosis in cancer cells via a redox-dependent mechanism. Anticancer Drugs (2005) 1.48
Role of the multidrug resistance protein-1 in hypertension and vascular dysfunction caused by angiotensin II. Arterioscler Thromb Vasc Biol (2007) 1.47
Oxidant-induced apoptosis in human retinal pigment epithelial cells: dependence on extracellular redox state. Invest Ophthalmol Vis Sci (2005) 1.47
Overexpressed human mitochondrial thioredoxin confers resistance to oxidant-induced apoptosis in human osteosarcoma cells. J Biol Chem (2002) 1.46
The role of the multidrug resistance protein-1 in modulation of endothelial cell oxidative stress. Circ Res (2005) 1.46
Lactobacillus rhamnosus blocks inflammatory signaling in vivo via reactive oxygen species generation. Free Radic Biol Med (2009) 1.45
Metabolic flexibility permits mesenchymal stem cell survival in an ischemic environment. Stem Cells (2008) 1.45
Designed tumor necrosis factor-related apoptosis-inducing ligand variants initiating apoptosis exclusively via the DR5 receptor. Proc Natl Acad Sci U S A (2006) 1.45
Differential oxidation of thioredoxin-1, thioredoxin-2, and glutathione by metal ions. Free Radic Biol Med (2005) 1.44
Predicting network activity from high throughput metabolomics. PLoS Comput Biol (2013) 1.44
Mitochondrial thioredoxin-2 has a key role in determining tumor necrosis factor-alpha-induced reactive oxygen species generation, NF-kappaB activation, and apoptosis. Toxicol Sci (2006) 1.43
Dietary supplementation with orotate and uracil increases adaptive growth of jejunal mucosa after massive small bowel resection in rats. JPEN J Parenter Enteral Nutr (2005) 1.43
Metabolic effects of albumin therapy in acute lung injury measured by proton nuclear magnetic resonance spectroscopy of plasma: a pilot study. Crit Care Med (2011) 1.42
HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction. PLoS Biol (2010) 1.42
Cysteine/cystine redox signaling in cardiovascular disease. Free Radic Biol Med (2010) 1.42
A practical approach to detect unique metabolic patterns for personalized medicine. Analyst (2010) 1.41
Glutathione and thioredoxin redox during differentiation in human colon epithelial (Caco-2) cells. Am J Physiol Gastrointest Liver Physiol (2002) 1.40
Prohibitin protects against oxidative stress in intestinal epithelial cells. FASEB J (2006) 1.39
A model of redox kinetics implicates the thiol proteome in cellular hydrogen peroxide responses. Antioxid Redox Signal (2010) 1.38
New directions in ER stress-induced cell death. Apoptosis (2013) 1.36
The unfolded protein response at the crossroads of cellular life and death during endoplasmic reticulum stress. Biol Cell (2012) 1.35
Extracellular cysteine/cystine redox potential controls lung fibroblast proliferation and matrix expression through upregulation of transforming growth factor-beta. Am J Physiol Lung Cell Mol Physiol (2007) 1.34
Stress-induced self-cannibalism: on the regulation of autophagy by endoplasmic reticulum stress. Cell Mol Life Sci (2012) 1.34
Mitochondrial thioredoxin-2/peroxiredoxin-3 system functions in parallel with mitochondrial GSH system in protection against oxidative stress. Arch Biochem Biophys (2007) 1.33
Association between adherence to the Mediterranean diet and oxidative stress. Am J Clin Nutr (2008) 1.32
Oxidative stress causes bone loss in estrogen-deficient mice through enhanced bone marrow dendritic cell activation. Proc Natl Acad Sci U S A (2007) 1.31
A key role for mitochondria in endothelial signaling by plasma cysteine/cystine redox potential. Free Radic Biol Med (2009) 1.31
Cysteine redox potential determines pro-inflammatory IL-1beta levels. PLoS One (2009) 1.30
Thiol redox disturbances in children with severe asthma are associated with posttranslational modification of the transcription factor nuclear factor (erythroid-derived 2)-like 2. J Allergy Clin Immunol (2011) 1.30
Glutathione depletion enforces the mitochondrial permeability transition and causes cell death in Bcl-2 overexpressing HL60 cells. FASEB J (2002) 1.30
Oxidation of nuclear thioredoxin during oxidative stress. FEBS Lett (2003) 1.27
Redox control systems in the nucleus: mechanisms and functions. Antioxid Redox Signal (2010) 1.25
Dieldrin exposure induces oxidative damage in the mouse nigrostriatal dopamine system. Exp Neurol (2007) 1.24
Clinical trials of antioxidants as cancer prevention agents: past, present, and future. Free Radic Biol Med (2011) 1.23
Oxidative stress is associated with impaired arterial elasticity. Atherosclerosis (2011) 1.23
Detectable serum flagellin and lipopolysaccharide and upregulated anti-flagellin and lipopolysaccharide immunoglobulins in human short bowel syndrome. Am J Physiol Regul Integr Comp Physiol (2007) 1.23
Attenuation of angiotensin II-induced vascular dysfunction and hypertension by overexpression of Thioredoxin 2. Hypertension (2009) 1.23
Mitochondrial thioredoxin in regulation of oxidant-induced cell death. FEBS Lett (2006) 1.22
Disruption of endothelial peroxisome proliferator-activated receptor-gamma reduces vascular nitric oxide production. Am J Physiol Heart Circ Physiol (2009) 1.22
Lipocalin 2 deficiency dysregulates iron homeostasis and exacerbates endotoxin-induced sepsis. J Immunol (2012) 1.22
Reactive aldehyde modification of thioredoxin-1 activates early steps of inflammation and cell adhesion. Am J Pathol (2007) 1.21
Extracellular cysteine/cystine redox regulates the p44/p42 MAPK pathway by metalloproteinase-dependent epidermal growth factor receptor signaling. Am J Physiol Gastrointest Liver Physiol (2005) 1.21
SOD1 targeted to the mitochondrial intermembrane space prevents motor neuropathy in the Sod1 knockout mouse. Brain (2010) 1.21
Inhibition of influenza infection by glutathione. Free Radic Biol Med (2003) 1.20
Selective protection of nuclear thioredoxin-1 and glutathione redox systems against oxidation during glucose and glutamine deficiency in human colonic epithelial cells. Free Radic Biol Med (2006) 1.19
Oxidation of extracellular cysteine/cystine redox state in bleomycin-induced lung fibrosis. Am J Physiol Lung Cell Mol Physiol (2008) 1.18
Increased expression of endoplasmic reticulum stress-related signaling pathway molecules in multiple sclerosis lesions. J Neuropathol Exp Neurol (2008) 1.17