Published in Genomics on May 23, 2007
Multiplex targeted sequencing identifies recurrently mutated genes in autism spectrum disorders. Science (2012) 6.21
Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion. Nat Genet (2012) 2.55
TBC1D14 regulates autophagosome formation via Rab11- and ULK1-positive recycling endosomes. J Cell Biol (2012) 2.00
RUTBC1 protein, a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins. J Biol Chem (2011) 1.25
An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes. Nat Genet (2015) 1.25
RUTBC2 protein, a Rab9A effector and GTPase-activating protein for Rab36. J Biol Chem (2012) 0.93
Evidence for age as a modifier of genetic associations for lipid levels. Ann Hum Genet (2011) 0.92
TBC-8, a putative RAB-2 GAP, regulates dense core vesicle maturation in Caenorhabditis elegans. PLoS Genet (2012) 0.82
Analysis of genome-wide copy number variations in Chinese indigenous and western pig breeds by 60 K SNP genotyping arrays. PLoS One (2014) 0.81
Autosomal dominant late-onset spinal motor neuronopathy is linked to a new locus on chromosome 22q11.2-q13.2. Eur J Hum Genet (2012) 0.80
RUFY, Rab and Rap Family Proteins Involved in a Regulation of Cell Polarity and Membrane Trafficking. Int J Mol Sci (2013) 0.79
Proteomic analysis of detergent resistant membrane domains during early interaction of macrophages with rough and smooth Brucella melitensis. PLoS One (2014) 0.77
Monoclonal antibodies against the connexin43-interacting protein CIP85. Hybridoma (Larchmt) (2009) 0.75
Functional Genomics Identifies Tis21-Dependent Mechanisms and Putative Cancer Drug Targets Underlying Medulloblastoma Shh-Type Development. Front Pharmacol (2016) 0.75
Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst (2005) 13.00
Integrative annotation of 21,037 human genes validated by full-length cDNA clones. PLoS Biol (2004) 7.17
The medaka draft genome and insights into vertebrate genome evolution. Nature (2007) 5.77
Genome sequence of the ultrasmall unicellular red alga Cyanidioschyzon merolae 10D. Nature (2004) 5.08
DMY is a Y-specific DM-domain gene required for male development in the medaka fish. Nature (2002) 4.73
Presence of epidermal growth factor receptor gene T790M mutation as a minor clone in non-small cell lung cancer. Cancer Res (2006) 4.72
Role of TBX1 in human del22q11.2 syndrome. Lancet (2003) 4.45
Somatic mutations of the HER2 kinase domain in lung adenocarcinomas. Cancer Res (2005) 4.25
Interleukin-22, a member of the IL-10 subfamily, induces inflammatory responses in colonic subepithelial myofibroblasts. Gastroenterology (2005) 3.65
Identification of eight members of the Argonaute family in the human genome. Genomics (2003) 3.55
LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death. Mol Cell (2002) 3.36
A duplicated copy of DMRT1 in the sex-determining region of the Y chromosome of the medaka, Oryzias latipes. Proc Natl Acad Sci U S A (2002) 3.20
The relationship between epidermal growth factor receptor mutations and clinicopathologic features in non-small cell lung cancers. Clin Cancer Res (2005) 3.11
A unified nomenclature for the superfamily of TRP cation channels. Mol Cell (2002) 2.99
A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming. Nat Genet (2009) 2.96
The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. Nucleic Acids Res (2007) 2.07
The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. Genome Res (2002) 2.03
Smoke exposure, histologic type and geography-related differences in the methylation profiles of non-small cell lung cancer. Int J Cancer (2003) 2.01
Spinocerebellar ataxia type 31 is associated with "inserted" penta-nucleotide repeats containing (TGGAA)n. Am J Hum Genet (2009) 1.96
Preoperative localization of small pulmonary lesions with a short hook wire and suture system: experience with 168 procedures. Radiology (2002) 1.96
Absence of the candidate male sex-determining gene dmrt1b(Y) of medaka from other fish species. Curr Biol (2003) 1.92
DNA sequence and analysis of human chromosome 8. Nature (2006) 1.91
Detection of EGFR gene mutation in lung cancer by mutant-enriched polymerase chain reaction assay. Clin Cancer Res (2006) 1.91
Recommendations of the 2006 Human Variome Project meeting. Nat Genet (2007) 1.90
XAGE-1 expression in non-small cell lung cancer and antibody response in patients. Clin Cancer Res (2005) 1.87
Piccolo, a Ca2+ sensor in pancreatic beta-cells. Involvement of cAMP-GEFII.Rim2. Piccolo complex in cAMP-dependent exocytosis. J Biol Chem (2002) 1.85
Endoscopic management of biliary complications after adult living donor liver transplantation. Am J Gastroenterol (2006) 1.78
Molecular cloning and expression analysis of a novel gene DGCR8 located in the DiGeorge syndrome chromosomal region. Biochem Biophys Res Commun (2003) 1.77
Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. Antimicrob Agents Chemother (2010) 1.74
Novel PINK1 mutations in early-onset parkinsonism. Ann Neurol (2004) 1.72
Genomic organization of the sex-determining and adjacent regions of the sex chromosomes of medaka. Genome Res (2006) 1.61
Efficacy and safety of low-pressured and short-time dilation in endoscopic papillary balloon dilation for bile duct stone removal. J Gastroenterol Hepatol (2007) 1.60
Nucleolar localization of DGCR8 and identification of eleven DGCR8-associated proteins. Exp Cell Res (2007) 1.60
Results of the Tokyo trial of prevention of post-ERCP pancreatitis with risperidone-2: a multicenter, randomized, placebo-controlled, double-blind clinical trial. Gastrointest Endosc (2013) 1.58
The transmembrane serine protease (TMPRSS3) mutated in deafness DFNB8/10 activates the epithelial sodium channel (ENaC) in vitro. Hum Mol Genet (2002) 1.58
Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population. Nat Genet (2012) 1.58
Interleukin-17 augments tumor necrosis factor-alpha-induced granulocyte and granulocyte/macrophage colony-stimulating factor release from human colonic myofibroblasts. J Gastroenterol (2005) 1.54
Mutational and epigenetic evidence for independent pathways for lung adenocarcinomas arising in smokers and never smokers. Cancer Res (2006) 1.53
Renal cancer cells lacking hypoxia inducible factor (HIF)-1alpha expression maintain vascular endothelial growth factor expression through HIF-2alpha. Carcinogenesis (2006) 1.49
Impact of introduction of wire-guided cannulation in therapeutic biliary endoscopic retrograde cholangiopancreatography. J Gastroenterol Hepatol (2011) 1.47
Aberrant promoter methylation of human DAB2 interactive protein (hDAB2IP) gene in lung cancers. Int J Cancer (2005) 1.45
Lower incidence of biliary carcinoma in patients with primary sclerosing cholangitis and high serum levels of immunoglobulin E. Clin Gastroenterol Hepatol (2011) 1.44
FTY720 reduces T-cell recruitment into murine intestinal allograft and prevents activation of graft-infiltrating cells. Transplantation (2003) 1.44
Long-term prognosis of autoimmune pancreatitis with and without corticosteroid treatment. Gut (2007) 1.43
Addition of a neutrophil elastase inhibitor to the organ flushing solution decreases lung reperfusion injury in rat lung transplantation. Eur J Cardiothorac Surg (2007) 1.43
Clinical utility of single-operator cholangiopancreatoscopy using a SpyGlass probe through an endoscopic retrograde cholangiopancreatography catheter. J Gastroenterol Hepatol (2012) 1.42
Aberrant promoter methylation in human DAB2 interactive protein (hDAB2IP) gene in breast cancer. Clin Cancer Res (2004) 1.39
Increased nuclear factor-kappa B activation is related to the tumor development of renal cell carcinoma. Carcinogenesis (2003) 1.37
Rapid and accurate identification of human-associated staphylococci by use of multiplex PCR. J Clin Microbiol (2011) 1.37
Efficacy and safety of luseogliflozin as monotherapy in Japanese patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled, phase 3 study. Curr Med Res Opin (2014) 1.37
Reduced expression of the REIC/Dkk-3 gene by promoter-hypermethylation in human tumor cells. Gene (2002) 1.34
Polymorphic segmental duplications at 8p23.1 challenge the determination of individual defensin gene repertoires and the assembly of a contiguous human reference sequence. BMC Genomics (2004) 1.32
Cholecystitis after metallic stent placement in patients with malignant distal biliary obstruction. Clin Gastroenterol Hepatol (2006) 1.31
Variants in optineurin gene and their association with tumor necrosis factor-alpha polymorphisms in Japanese patients with glaucoma. Invest Ophthalmol Vis Sci (2004) 1.28
Caffeic acid phenethyl ester induces apoptosis by inhibition of NFkappaB and activation of Fas in human breast cancer MCF-7 cells. J Biol Chem (2003) 1.27
MEPD: a resource for medaka gene expression patterns. Bioinformatics (2005) 1.22
Genomic structure and functional control of the Dlx3-7 bigene cluster. Proc Natl Acad Sci U S A (2002) 1.22
Measurement of radial and axial forces of biliary self-expandable metallic stents. Gastrointest Endosc (2009) 1.22
Aberrant methylation of HIN-1 (high in normal-1) is a frequent event in many human malignancies. Int J Cancer (2005) 1.21
AIRE functions as an E3 ubiquitin ligase. J Exp Med (2004) 1.19
Smqnr, a new chromosome-carried quinolone resistance gene in Stenotrophomonas maltophilia. Antimicrob Agents Chemother (2008) 1.18
Development of vaccine strains of H5 and H7 influenza viruses. Jpn J Vet Res (2008) 1.18
Two novel mutations in the EYS gene are possible major causes of autosomal recessive retinitis pigmentosa in the Japanese population. PLoS One (2012) 1.17
Medaka genomics: a bridge between mutant phenotype and gene function. Mech Dev (2004) 1.17
Frequent translocations occur between low copy repeats on chromosome 22q11.2 (LCR22s) and telomeric bands of partner chromosomes. Hum Mol Genet (2003) 1.17
Dose-finding study of luseogliflozin in Japanese patients with type 2 diabetes mellitus: a 12-week, randomized, double-blind, placebo-controlled, phase II study. Curr Med Res Opin (2014) 1.16
Electrotransformation of Lactobacillus delbrueckii subsp. bulgaricus and L. delbrueckii subsp. lactis with various plasmids. Appl Environ Microbiol (2002) 1.16
Aberrant promoter methylation of insulin-like growth factor binding protein-3 gene in human cancers. Int J Cancer (2007) 1.16
Expression of AIRE gene in peripheral monocyte/dendritic cell lineage. Immunol Lett (2002) 1.16
Usefulness of EGFR mutation screening in pleural fluid to predict the clinical outcome of gefitinib treated patients with lung cancer. Int J Cancer (2006) 1.15
Genetic diversity of staphylocoagulase genes (coa): insight into the evolution of variable chromosomal virulence factors in Staphylococcus aureus. PLoS One (2009) 1.14
Genomic analysis of Hox clusters in the sea lamprey Petromyzon marinus. J Exp Zool (2002) 1.14
Pneumothorax, pleural effusion, and chest tube placement after radiofrequency ablation of lung tumors: incidence and risk factors. Radiology (2006) 1.13
Clinical outcomes of chemotherapy for diabetic and nondiabetic patients with pancreatic cancer: better prognosis with statin use in diabetic patients. Pancreas (2013) 1.12
Efficacy and safety of luseogliflozin monotherapy in Japanese patients with type 2 diabetes mellitus: a 12-week, randomized, placebo-controlled, phase II study. Curr Med Res Opin (2014) 1.12
A novel giant gene CSMD3 encoding a protein with CUB and sushi multiple domains: a candidate gene for benign adult familial myoclonic epilepsy on human chromosome 8q23.3-q24.1. Biochem Biophys Res Commun (2003) 1.12
Management of distal malignant biliary obstruction with the ComVi stent, a new covered metallic stent. Surg Endosc (2009) 1.11
Thoracoscopic operation with local and epidural anesthesia in the treatment of pneumothorax after lung transplantation. J Thorac Cardiovasc Surg (2005) 1.10
Slow pull versus suction in endoscopic ultrasound-guided fine-needle aspiration of pancreatic solid masses. Dig Dis Sci (2014) 1.09
The impact of epidermal growth factor receptor gene status on gefitinib-treated Japanese patients with non-small-cell lung cancer. Int J Cancer (2007) 1.09