Published in J Biol Chem on October 24, 2002
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The intracellular II-III loops of Cav1.2 and Cav1.3 uncouple L-type voltage-gated Ca2+ channels from glucagon-like peptide-1 potentiation of insulin secretion in INS-1 cells via displacement from lipid rafts. J Pharmacol Exp Ther (2009) 0.86
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Cyclic AMP dynamics in the pancreatic β-cell. Ups J Med Sci (2012) 0.84
Sequential onset of presynaptic molecules during olfactory sensory neuron maturation. J Comp Neurol (2009) 0.83
Inflammation-Mediated Regulation of MicroRNA Expression in Transplanted Pancreatic Islets. J Transplant (2012) 0.83
Rap1 promotes multiple pancreatic islet cell functions and signals through mammalian target of rapamycin complex 1 to enhance proliferation. J Biol Chem (2010) 0.82
Nerve growth factor mediates a switch in intracellular signaling for PGE2-induced sensitization of sensory neurons from protein kinase A to Epac. PLoS One (2014) 0.82
Piccolo Directs Activity Dependent F-Actin Assembly from Presynaptic Active Zones via Daam1. PLoS One (2015) 0.82
Differential distribution of exchange proteins directly activated by cyclic AMP within the adult rat retina. Neuroscience (2009) 0.81
In vivo knockdown of Piccolino disrupts presynaptic ribbon morphology in mouse photoreceptor synapses. Front Cell Neurosci (2014) 0.79
Glucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: A Long March to Therapeutic Successes. Pharmacol Rev (2016) 0.78
Potentiation of sulfonylurea action by an EPAC-selective cAMP analog in INS-1 cells: comparison of tolbutamide and gliclazide and a potential role for EPAC activation of a 2-APB-sensitive Ca2+ influx. Mol Pharmacol (2012) 0.78
Insulin secretion from beta cells within intact islets: location matters. Clin Exp Pharmacol Physiol (2015) 0.78
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Uncoupling of Cav1.2 from Ca(2+)-induced Ca(2+) release and SK channel regulation in pancreatic β-cells. Mol Endocrinol (2014) 0.77
Fife organizes synaptic vesicles and calcium channels for high-probability neurotransmitter release. J Cell Biol (2016) 0.76
PCLO variants are nominally associated with early-onset type 2 diabetes and insulin resistance in Pima Indians. Diabetes (2008) 0.75
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Retracted Valsartan in a Japanese population with hypertension and other cardiovascular disease (Jikei Heart Study): a randomised, open-label, blinded endpoint morbidity-mortality study. Lancet (2007) 5.17
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Role of TBX1 in human del22q11.2 syndrome. Lancet (2003) 4.45
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PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis. Physiol Rev (2005) 3.12
A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming. Nat Genet (2009) 2.96
Role of sarcolemmal K(ATP) channels in cardioprotection against ischemia/reperfusion injury in mice. J Clin Invest (2002) 2.74
Kir6.2 is required for adaptation to stress. Proc Natl Acad Sci U S A (2002) 2.60
Essential role of Epac2/Rap1 signaling in regulation of insulin granule dynamics by cAMP. Proc Natl Acad Sci U S A (2007) 2.59
Identification of multiple isolated lymphoid follicles on the antimesenteric wall of the mouse small intestine. J Immunol (2002) 2.57
Mouse model of Prinzmetal angina by disruption of the inward rectifier Kir6.1. Nat Med (2002) 2.45
GLP-1 receptor activation and Epac2 link atrial natriuretic peptide secretion to control of blood pressure. Nat Med (2013) 2.31
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PGRN is a key adipokine mediating high fat diet-induced insulin resistance and obesity through IL-6 in adipose tissue. Cell Metab (2012) 2.24
Age- and sex-specific prevalence of diabetes and impaired glucose regulation in 11 Asian cohorts. Diabetes Care (2003) 2.18
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Cyclic GMP-dependent protein kinase II is a molecular switch from proliferation to hypertrophic differentiation of chondrocytes. Genes Dev (2004) 2.00
Postprandial glucose regulation and diabetic complications. Arch Intern Med (2004) 1.97
DNA sequence and analysis of human chromosome 8. Nature (2006) 1.91
The cAMP sensor Epac2 is a direct target of antidiabetic sulfonylurea drugs. Science (2009) 1.90
Dynamics of insulin secretion and the clinical implications for obesity and diabetes. J Clin Invest (2011) 1.90
Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine cells and mucosal mast cells in rat intestine. Cell Tissue Res (2006) 1.90
Lineage tracing and characterization of insulin-secreting cells generated from adult pancreatic acinar cells. Proc Natl Acad Sci U S A (2005) 1.87
Cardioprotective effect of diazoxide is mediated by activation of sarcolemmal but not mitochondrial ATP-sensitive potassium channels in mice. Circulation (2003) 1.84
Nomenclature of the GLUT/SLC2A family of sugar/polyol transport facilitators. Am J Physiol Endocrinol Metab (2002) 1.82
Endoscopic management of biliary complications after adult living donor liver transplantation. Am J Gastroenterol (2006) 1.78
Molecular cloning and expression analysis of a novel gene DGCR8 located in the DiGeorge syndrome chromosomal region. Biochem Biophys Res Commun (2003) 1.77
Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. Antimicrob Agents Chemother (2010) 1.74
KATP channel knockout worsens myocardial calcium stress load in vivo and impairs recovery in stunned heart. Am J Physiol Heart Circ Physiol (2006) 1.74
Protection conferred by myocardial ATP-sensitive K+ channels in pressure overload-induced congestive heart failure revealed in KCNJ11 Kir6.2-null mutant. J Physiol (2006) 1.70
LKB1 regulates pancreatic beta cell size, polarity, and function. Cell Metab (2009) 1.70
Upregulation of heat shock transcription factor 1 plays a critical role in adaptive cardiac hypertrophy. Circ Res (2006) 1.66
Interaction of ATP sensor, cAMP sensor, Ca2+ sensor, and voltage-dependent Ca2+ channel in insulin granule exocytosis. J Biol Chem (2003) 1.66
Hemodynamics in vasculogenic mimicry and angiogenesis of inflammatory breast cancer xenograft. Cancer Res (2002) 1.64
Cloning and characterization of a novel mammalian zinc transporter, zinc transporter 5, abundantly expressed in pancreatic beta cells. J Biol Chem (2002) 1.63
Cblb is a major susceptibility gene for rat type 1 diabetes mellitus. Nat Genet (2002) 1.63
International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels. Pharmacol Rev (2005) 1.63
Roles of KATP channels as metabolic sensors in acute metabolic changes. J Mol Cell Cardiol (2005) 1.62
K-ATP channels promote the differential degeneration of dopaminergic midbrain neurons. Nat Neurosci (2005) 1.62
Genomic organization of the sex-determining and adjacent regions of the sex chromosomes of medaka. Genome Res (2006) 1.61
Nucleolar localization of DGCR8 and identification of eleven DGCR8-associated proteins. Exp Cell Res (2007) 1.60
Efficacy and safety of low-pressured and short-time dilation in endoscopic papillary balloon dilation for bile duct stone removal. J Gastroenterol Hepatol (2007) 1.60
Results of the Tokyo trial of prevention of post-ERCP pancreatitis with risperidone-2: a multicenter, randomized, placebo-controlled, double-blind clinical trial. Gastrointest Endosc (2013) 1.58
Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population. Nat Genet (2012) 1.58
KATP channel mutation confers risk for vein of Marshall adrenergic atrial fibrillation. Nat Clin Pract Cardiovasc Med (2007) 1.56
Knockout of Kir6.2 negates ischemic preconditioning-induced protection of myocardial energetics. Am J Physiol Heart Circ Physiol (2003) 1.56
Amelioration of dextran sulfate sodium-induced colitis by anti-macrophage migration inhibitory factor antibody in mice. Gastroenterology (2002) 1.54
KCNJ11 gene knockout of the Kir6.2 KATP channel causes maladaptive remodeling and heart failure in hypertension. Hum Mol Genet (2006) 1.53
ATP-sensitive K+ channel knockout compromises the metabolic benefit of exercise training, resulting in cardiac deficits. Diabetes (2004) 1.53
Pravastatin for cardiovascular event primary prevention in patients with mild-to-moderate hypertension in the Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese (MEGA) Study. Hypertension (2008) 1.50
Impact of introduction of wire-guided cannulation in therapeutic biliary endoscopic retrograde cholangiopancreatography. J Gastroenterol Hepatol (2011) 1.47
FTY720 reduces T-cell recruitment into murine intestinal allograft and prevents activation of graft-infiltrating cells. Transplantation (2003) 1.44
Lower incidence of biliary carcinoma in patients with primary sclerosing cholangitis and high serum levels of immunoglobulin E. Clin Gastroenterol Hepatol (2011) 1.44
Long-term prognosis of autoimmune pancreatitis with and without corticosteroid treatment. Gut (2007) 1.43
Clinical utility of single-operator cholangiopancreatoscopy using a SpyGlass probe through an endoscopic retrograde cholangiopancreatography catheter. J Gastroenterol Hepatol (2012) 1.42
An endothelial-mesenchymal relay pathway regulates early phases of pancreas development. Dev Biol (2006) 1.39
Embryonic stem cell therapy of heart failure in genetic cardiomyopathy. Stem Cells (2008) 1.39
Rapid and accurate identification of human-associated staphylococci by use of multiplex PCR. J Clin Microbiol (2011) 1.37
Efficacy and safety of luseogliflozin as monotherapy in Japanese patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled, phase 3 study. Curr Med Res Opin (2014) 1.37
Usefulness of pravastatin in primary prevention of cardiovascular events in women: analysis of the Management of Elevated Cholesterol in the Primary Prevention Group of Adult Japanese (MEGA study). Circulation (2008) 1.33
Cholecystitis after metallic stent placement in patients with malignant distal biliary obstruction. Clin Gastroenterol Hepatol (2006) 1.31
Gene knockout of the KCNJ8-encoded Kir6.1 K(ATP) channel imparts fatal susceptibility to endotoxemia. FASEB J (2006) 1.28
Macrophage-derived AIM is endocytosed into adipocytes and decreases lipid droplets via inhibition of fatty acid synthase activity. Cell Metab (2010) 1.27
Chondrogenic differentiation of bovine bone marrow mesenchymal stem cells in pellet cultural system. Exp Hematol (2004) 1.25
ATP-sensitive potassium channels participate in glucose uptake in skeletal muscle and adipose tissue. Am J Physiol Endocrinol Metab (2002) 1.25
K-ATP channels in dopamine substantia nigra neurons control bursting and novelty-induced exploration. Nat Neurosci (2012) 1.24
Postprandial hyperglycaemia and cardiovascular complications of diabetes: an update. Nutr Metab Cardiovasc Dis (2006) 1.24
The Rho-kinase inhibitor, fasudil, attenuates diabetic nephropathy in streptozotocin-induced diabetic rats. Eur J Pharmacol (2007) 1.23
Genetic disruption of Kir6.2, the pore-forming subunit of ATP-sensitive K+ channel, predisposes to catecholamine-induced ventricular dysrhythmia. Diabetes (2004) 1.23
MEPD: a resource for medaka gene expression patterns. Bioinformatics (2005) 1.22
Measurement of radial and axial forces of biliary self-expandable metallic stents. Gastrointest Endosc (2009) 1.22
Postprandial glucose regulation: new data and new implications. Clin Ther (2005) 1.22
Long-term mortality in nationwide cohorts of childhood-onset type 1 diabetes in Japan and Finland. Diabetes Care (2003) 1.21
Population-based assessment of familial clustering of diabetic nephropathy in type 1 diabetes. Diabetes (2004) 1.21
Nonpungent capsaicin analogs (capsinoids) increase energy expenditure through the activation of brown adipose tissue in humans. Am J Clin Nutr (2012) 1.19
Smqnr, a new chromosome-carried quinolone resistance gene in Stenotrophomonas maltophilia. Antimicrob Agents Chemother (2008) 1.18
Development of vaccine strains of H5 and H7 influenza viruses. Jpn J Vet Res (2008) 1.18
GPR expression in the rat taste bud relating to fatty acid sensing. Biomed Res (2007) 1.18
Is the measurement of glycated hemoglobin A1c alone an efficient screening test for undiagnosed diabetes? Japan National Diabetes Survey. Diabetes Res Clin Pract (2006) 1.17
Frequent translocations occur between low copy repeats on chromosome 22q11.2 (LCR22s) and telomeric bands of partner chromosomes. Hum Mol Genet (2003) 1.17
Genetic and environmental effects on fasting and postchallenge plasma glucose and serum insulin values in Finnish twins. J Clin Endocrinol Metab (2005) 1.17
Screen-detected diabetes, hypertension and hypercholesterolemia as predictors of cardiovascular mortality in five populations of Asian origin: the DECODA study. Eur J Cardiovasc Prev Rehabil (2006) 1.16
Electrotransformation of Lactobacillus delbrueckii subsp. bulgaricus and L. delbrueckii subsp. lactis with various plasmids. Appl Environ Microbiol (2002) 1.16
Dose-finding study of luseogliflozin in Japanese patients with type 2 diabetes mellitus: a 12-week, randomized, double-blind, placebo-controlled, phase II study. Curr Med Res Opin (2014) 1.16
Distinct effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 on insulin secretion and gut motility. Diabetes (2005) 1.16
Genetic diversity of staphylocoagulase genes (coa): insight into the evolution of variable chromosomal virulence factors in Staphylococcus aureus. PLoS One (2009) 1.14
Roles of ATP-sensitive K+ channels as metabolic sensors: studies of Kir6.x null mice. Diabetes (2004) 1.13
Clinical outcomes of chemotherapy for diabetic and nondiabetic patients with pancreatic cancer: better prognosis with statin use in diabetic patients. Pancreas (2013) 1.12
Efficacy and safety of luseogliflozin monotherapy in Japanese patients with type 2 diabetes mellitus: a 12-week, randomized, placebo-controlled, phase II study. Curr Med Res Opin (2014) 1.12