Published in J Mol Biol on April 18, 2003
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In vivo imaging of labelled endogenous β-actin mRNA during nucleocytoplasmic transport. Nature (2010) 2.16
Structural evidence for common ancestry of the nuclear pore complex and vesicle coats. Science (2008) 2.15
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The nuclear pore complex has entered the atomic age. Structure (2009) 2.07
A nucleoporin is required for induction of Ca2+ spiking in legume nodule development and essential for rhizobial and fungal symbiosis. Proc Natl Acad Sci U S A (2006) 1.85
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Energy- and temperature-dependent transport of integral proteins to the inner nuclear membrane via the nuclear pore. J Cell Biol (2004) 1.58
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HIV infection of non-dividing cells: a divisive problem. Retrovirology (2006) 1.33
Visualizing single molecules interacting with nuclear pore complexes by narrow-field epifluorescence microscopy. Methods (2006) 1.30
Molecular architecture of the Nup84-Nup145C-Sec13 edge element in the nuclear pore complex lattice. Nat Struct Mol Biol (2009) 1.23
Architectural nucleoporins Nup157/170 and Nup133 are structurally related and descend from a second ancestral element. J Biol Chem (2009) 1.22
Single-molecule measurements of importin alpha/cargo complex dissociation at the nuclear pore. Proc Natl Acad Sci U S A (2008) 1.17
The role of nuclear pores in gene regulation, development and disease. EMBO Rep (2009) 1.17
The yeast integral membrane protein Apq12 potentially links membrane dynamics to assembly of nuclear pore complexes. J Cell Biol (2007) 1.12
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The karyopherin Kap95 regulates nuclear pore complex assembly into intact nuclear envelopes in vivo. Mol Biol Cell (2006) 1.04
The integral membrane protein Pom34p functionally links nucleoporin subcomplexes. Genetics (2005) 1.03
Crystal structure of the N-terminal domain of the human protooncogene Nup214/CAN. Proc Natl Acad Sci U S A (2007) 1.00
Facilitated transport and diffusion take distinct spatial routes through the nuclear pore complex. J Cell Sci (2010) 1.00
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Transportin regulates major mitotic assembly events: from spindle to nuclear pore assembly. Mol Biol Cell (2009) 0.98
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Atomic force microscopy visualises a hydrophobic meshwork in the central channel of the nuclear pore. Pflugers Arch (2007) 0.88
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Functional insights of nucleocytoplasmic transport in plants. Front Plant Sci (2014) 0.85
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The nucleoporin Nup88 is interacting with nuclear lamin A. Mol Biol Cell (2011) 0.84
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Choreography of importin-α/CAS complex assembly and disassembly at nuclear pores. Proc Natl Acad Sci U S A (2013) 0.82
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Alignment algorithms and per-particle CTF correction for single particle cryo-electron tomography. J Struct Biol (2016) 0.79
Calcium regulation of nucleocytoplasmic transport. Protein Cell (2011) 0.79
Nucleoporin 62-like protein activates canonical Wnt signaling through facilitating the nuclear import of β-catenin in zebrafish. Mol Cell Biol (2015) 0.79
Cryo-electron tomography: an ideal method to study membrane-associated proteins. Philos Trans R Soc Lond B Biol Sci (2017) 0.78
Structural characterization of altered nucleoporin Nup153 expression in human cells by thin-section electron microscopy. Nucleus (2014) 0.78
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Rapid Brownian Motion Primes Ultrafast Reconstruction of Intrinsically Disordered Phe-Gly Repeats Inside the Nuclear Pore Complex. Sci Rep (2016) 0.76
Mapping ubiquitin modifications reveals new functions for the yeast nuclear pore complex. Cell Logist (2012) 0.76
Single hepatitis-B virus core capsid binding to individual nuclear pore complexes in Hela cells. Biophys J (2006) 0.75
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Complex Commingling: Nucleoporins and the Spindle Assembly Checkpoint. Cells (2015) 0.75
Predicting the nuclear localization signals of 107 types of HPV L1 proteins by bioinformatic analysis. Genomics Proteomics Bioinformatics (2006) 0.75
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Induction of autophagy by spermidine promotes longevity. Nat Cell Biol (2009) 5.00
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The nanomechanical signature of breast cancer. Nat Nanotechnol (2012) 2.89
The nuclear pore complex: nucleocytoplasmic transport and beyond. Nat Rev Mol Cell Biol (2003) 2.77
Validation of the contemporary epstein criteria for insignificant prostate cancer in European men. Eur Urol (2007) 2.50
Modular self-assembly of a Y-shaped multiprotein complex from seven nucleoporins. EMBO J (2002) 2.47
Nanomechanical basis of selective gating by the nuclear pore complex. Science (2007) 2.44
Frozen section for the management of intraoperatively detected palpable tumor lesions during nerve-sparing scheduled radical prostatectomy. Eur Urol (2006) 2.21
Dynamic elastic modulus of porcine articular cartilage determined at two different levels of tissue organization by indentation-type atomic force microscopy. Biophys J (2004) 2.20
Early detection of aging cartilage and osteoarthritis in mice and patient samples using atomic force microscopy. Nat Nanotechnol (2009) 2.19
Flexible phenylalanine-glycine nucleoporins as entropic barriers to nucleocytoplasmic transport. Proc Natl Acad Sci U S A (2006) 2.16
Lamin A/C-dependent localization of Nesprin-2, a giant scaffolder at the nuclear envelope. Mol Biol Cell (2005) 2.15
Multiple assembly pathways underlie amyloid-beta fibril polymorphisms. J Mol Biol (2005) 2.14
High provider volume is associated with lower rate of secondary therapies after definitive radiotherapy for localized prostate cancer. Eur Urol (2007) 2.02
Identification of macromolecular complexes in cryoelectron tomograms of phantom cells. Proc Natl Acad Sci U S A (2002) 1.98
Development and internal validation of a nomogram predicting the probability of prostate cancer Gleason sum upgrading between biopsy and radical prostatectomy pathology. Eur Urol (2005) 1.97
Hrr25-dependent phosphorylation state regulates organization of the pre-40S subunit. Nature (2006) 1.95
Improved prediction of disease relapse after radical prostatectomy through a panel of preoperative blood-based biomarkers. Clin Cancer Res (2008) 1.90
Development and external validation of an extended 10-core biopsy nomogram. Eur Urol (2006) 1.90
Intermediate filaments: primary determinants of cell architecture and plasticity. J Clin Invest (2009) 1.88
Exploring the 3D molecular architecture of Escherichia coli type 1 pili. J Mol Biol (2002) 1.81
Initial prostate biopsy: development and internal validation of a biopsy-specific nomogram based on the prostate cancer antigen 3 assay. Eur Urol (2012) 1.81
Domain-specific antibodies reveal multiple-site topology of Nup153 within the nuclear pore complex. J Struct Biol (2002) 1.76
Conserved segments 1A and 2B of the intermediate filament dimer: their atomic structures and role in filament assembly. EMBO J (2002) 1.73
The S. cerevisiae HtrA-like protein Nma111p is a nuclear serine protease that mediates yeast apoptosis. J Cell Sci (2004) 1.62
Vimentin organization modulates the formation of lamellipodia. Mol Biol Cell (2011) 1.60
The parallel superpleated beta-structure as a model for amyloid fibrils of human amylin. J Mol Biol (2005) 1.56
The nuclear pore complex: a jack of all trades? Trends Biochem Sci (2004) 1.55
Poor overall survival in septa- and octogenarian patients after radical prostatectomy and radiotherapy for prostate cancer: a population-based study of 6183 men. Eur Urol (2007) 1.51
Survival after radical prostatectomy and radiotherapy for prostate cancer: a population-based study. Can Urol Assoc J (2009) 1.51
A nonadjuvanted polypeptide nanoparticle vaccine confers long-lasting protection against rodent malaria. J Immunol (2009) 1.50
Prognostic value of syndecan-1 expression in patients treated with radical prostatectomy. BJU Int (2007) 1.50
Design of a microfabricated, two-electrode phase-contrast element suitable for electron microscopy. Ultramicroscopy (2006) 1.49
Nucleoporin domain topology is linked to the transport status of the nuclear pore complex. J Mol Biol (2005) 1.48
Actin in the nucleus: what form and what for? J Struct Biol (2002) 1.46
Prostate-specific antigen improves the ability of clinical stage and biopsy Gleason sum to predict the pathologic stage at radical prostatectomy in the new millennium. Eur Urol (2007) 1.45
Contemporary prostate cancer prevalence among T1c biopsy-referred men with a prostate-specific antigen level < or = 4.0 ng per milliliter. Eur Urol (2007) 1.45
Towards reconciling structure and function in the nuclear pore complex. Histochem Cell Biol (2008) 1.45
Full-length rat amylin forms fibrils following substitution of single residues from human amylin. J Mol Biol (2003) 1.44
Prediction of pathological stage is inaccurate in men with PSA values above 20 ng/mL. Eur Urol (2006) 1.42
The biology of desmin filaments: how do mutations affect their structure, assembly, and organisation? J Struct Biol (2004) 1.42
Crystal structure of the human lamin A coil 2B dimer: implications for the head-to-tail association of nuclear lamins. J Mol Biol (2004) 1.42
Molecular architecture of intermediate filaments. Bioessays (2003) 1.40
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Critical assessment of tools to predict clinically insignificant prostate cancer at radical prostatectomy in contemporary men. Cancer (2008) 1.39
Towards a molecular description of intermediate filament structure and assembly. Exp Cell Res (2007) 1.38
The 2002 AJCC pT2 substages confer no prognostic information on the rate of biochemical recurrence after radical prostatectomy. Eur Urol (2006) 1.38
Clinical significance of epidermal growth factor receptor protein overexpression and gene copy number gains in prostate cancer. Clin Cancer Res (2007) 1.36
Nuclear actin extends, with no contraction in sight. Mol Biol Cell (2005) 1.36
Towards an integrated understanding of the structure and mechanics of the cell nucleus. Bioessays (2008) 1.35
A pre-ribosome with a tadpole-like structure functions in ATP-dependent maturation of 60S subunits. Mol Cell (2004) 1.34
Molecular and biophysical characterization of assembly-starter units of human vimentin. J Mol Biol (2004) 1.33
Human amylin oligomer growth and fibril elongation define two distinct phases in amyloid formation. J Biol Chem (2004) 1.33
Structure-based design of peptides that self-assemble into regular polyhedral nanoparticles. Nanomedicine (2006) 1.32
Severe muscle disease-causing desmin mutations interfere with in vitro filament assembly at distinct stages. Proc Natl Acad Sci U S A (2005) 1.30
The nuclear pore complex up close. Curr Opin Cell Biol (2006) 1.30
Tracking down the different forms of nuclear actin. Trends Cell Biol (2006) 1.29
Functional complexity of intermediate filament cytoskeletons: from structure to assembly to gene ablation. Int Rev Cytol (2003) 1.28
Tensile properties of single desmin intermediate filaments. Biophys J (2008) 1.28
Micro- and nanomechanical analysis of articular cartilage by indentation-type atomic force microscopy: validation with a gel-microfiber composite. Biophys J (2010) 1.26
Sac3 is an mRNA export factor that localizes to cytoplasmic fibrils of nuclear pore complex. Mol Biol Cell (2003) 1.26
A quantitative kinetic model for the in vitro assembly of intermediate filaments from tetrameric vimentin. J Biol Chem (2007) 1.25
The highly conserved nuclear lamin Ig-fold binds to PCNA: its role in DNA replication. J Cell Biol (2008) 1.24
Isolation, characterization, and in vitro assembly of intermediate filaments. Methods Cell Biol (2004) 1.23
Self-assembly of human MxA GTPase into highly ordered dynamin-like oligomers. J Biol Chem (2002) 1.21
Myomesin is a molecular spring with adaptable elasticity. J Mol Biol (2005) 1.21
The inhibitor-of-apoptosis protein Bir1p protects against apoptosis in S. cerevisiae and is a substrate for the yeast homologue of Omi/HtrA2. J Cell Sci (2006) 1.20
Tumour volume and high grade tumour volume are the best predictors of pathologic stage and biochemical recurrence after radical prostatectomy. Eur J Cancer (2007) 1.19
Structural analysis of a metazoan nuclear pore complex reveals a fused concentric ring architecture. J Mol Biol (2009) 1.19
External validation of a biomarker-based preoperative nomogram predicts biochemical recurrence after radical prostatectomy. J Clin Oncol (2008) 1.18
Early parenteral nutrition evokes a phenotype of autophagy deficiency in liver and skeletal muscle of critically ill rabbits. Endocrinology (2012) 1.18
Laminopathic mutations interfere with the assembly, localization, and dynamics of nuclear lamins. Proc Natl Acad Sci U S A (2007) 1.17
Open retropubic nerve-sparing radical prostatectomy. Eur Urol (2005) 1.16
The core of tau-paired helical filaments studied by scanning transmission electron microscopy and limited proteolysis. Biochemistry (2006) 1.16
Ca2+ -dependent interaction of S100A1 with F1-ATPase leads to an increased ATP content in cardiomyocytes. Mol Cell Biol (2007) 1.16
Surgical volume is related to the rate of positive surgical margins at radical prostatectomy in European patients. BJU Int (2006) 1.15
The nanomechanical properties of rat fibroblasts are modulated by interfering with the vimentin intermediate filament system. J Struct Biol (2011) 1.14
Localization of uroplakin Ia, the urothelial receptor for bacterial adhesin FimH, on the six inner domains of the 16 nm urothelial plaque particle. J Mol Biol (2002) 1.14
Precise beam-tilt alignment and collimation are required to minimize the phase error associated with coma in high-resolution cryo-EM. J Struct Biol (2010) 1.13
Monitoring intermediate filament assembly by small-angle x-ray scattering reveals the molecular architecture of assembly intermediates. Proc Natl Acad Sci U S A (2006) 1.13
Characterization of early assembly intermediates of recombinant human keratins. J Struct Biol (2002) 1.12
Nucleoporins: leaving the nuclear pore complex for a successful mitosis. Cell Signal (2011) 1.11
Vimentin coil 1A-A molecular switch involved in the initiation of filament elongation. J Mol Biol (2009) 1.10
Atomic structure of the vimentin central α-helical domain and its implications for intermediate filament assembly. Proc Natl Acad Sci U S A (2012) 1.10
Characterization of the head-to-tail overlap complexes formed by human lamin A, B1 and B2 "half-minilamin" dimers. J Mol Biol (2009) 1.10
The supramolecular organization of the C. elegans nuclear lamin filament. J Mol Biol (2008) 1.10
Lamin A and lamin C form homodimers and coexist in higher complex forms both in the nucleoplasmic fraction and in the lamina of cultured human cells. Nucleus (2011) 1.10
Prostate volume and adverse prostate cancer features: fact not artifact. Eur J Cancer (2007) 1.09
Cryoelectron microscopy and cryoelectron tomography of the nuclear pre-mRNA processing machine. J Struct Biol (2002) 1.08
Atomic structure of vimentin coil 2. J Struct Biol (2010) 1.07
Distinct subcellular location of the Ca2+-binding protein S100A1 differentially modulates Ca2+-cycling in ventricular rat cardiomyocytes. J Cell Sci (2005) 1.06
From the trap to the basket: getting to the bottom of the nuclear pore complex. Chromosoma (2006) 1.06