Published in Trends Cell Biol on July 07, 2006
Nuclear shape, mechanics, and mechanotransduction. Circ Res (2008) 3.12
Gamma-actin is required for cytoskeletal maintenance but not development. Proc Natl Acad Sci U S A (2009) 1.74
Nuclear myosin I acts in concert with polymeric actin to drive RNA polymerase I transcription. Genes Dev (2008) 1.63
The nuclear F-actin interactome of Xenopus oocytes reveals an actin-bundling kinesin that is essential for meiotic cytokinesis. EMBO J (2013) 1.58
Nuclear functions of actin. Cold Spring Harb Perspect Biol (2010) 1.55
Phase transitions and size scaling of membrane-less organelles. J Cell Biol (2013) 1.46
A nuclear F-actin scaffold stabilizes ribonucleoprotein droplets against gravity in large cells. Nat Cell Biol (2013) 1.19
Depletion of nuclear actin is a key mediator of quiescence in epithelial cells. J Cell Sci (2011) 1.16
Flotillins interact with PSGL-1 in neutrophils and, upon stimulation, rapidly organize into membrane domains subsequently accumulating in the uropod. PLoS One (2009) 1.13
The F-actin severing protein cofilin-1 is required for RNA polymerase II transcription elongation. Nucleus (2011) 1.13
SUMOylation of nuclear actin. J Cell Biol (2009) 1.08
Induction of HoxB transcription by retinoic acid requires actin polymerization. Mol Biol Cell (2009) 1.03
Nuclear actin filaments recruit cofilin and actin-related protein 3, and their formation is connected with a mitotic block. Histochem Cell Biol (2014) 1.01
A single vegetative actin isovariant overexpressed under the control of multiple regulatory sequences is sufficient for normal Arabidopsis development. Plant Cell (2009) 0.95
Ultrastructural localization of actin and actin-binding proteins in the nucleus. Histochem Cell Biol (2008) 0.93
G-actin participates in RNA polymerase II-dependent transcription elongation by recruiting positive transcription elongation factor b (P-TEFb). J Biol Chem (2011) 0.92
Proteome analysis of human nuclear insoluble fractions. Genes Cells (2009) 0.90
Subcellular localization and Ser-137 phosphorylation regulate tumor-suppressive activity of profilin-1. J Biol Chem (2015) 0.89
Espin actin-cytoskeletal proteins are in rat type I spiral ganglion neurons and include splice-isoforms with a functional nuclear localization signal. J Comp Neurol (2008) 0.88
Pathogenic polyglutamine proteins cause dendrite defects associated with specific actin cytoskeletal alterations in Drosophila. Proc Natl Acad Sci U S A (2011) 0.87
Analysis of nuclear actin by overexpression of wild-type and actin mutant proteins. Histochem Cell Biol (2013) 0.85
Mechanics of the nucleus. Compr Physiol (2011) 0.85
Actin: its cumbersome pilgrimage through cellular compartments. Histochem Cell Biol (2008) 0.84
Emerging roles of sumoylation in the regulation of actin, microtubules, intermediate filaments, and septins. Cytoskeleton (Hoboken) (2015) 0.83
Nuclear actin depolymerization in transcriptionally active avian and amphibian oocytes leads to collapse of intranuclear structures. Nucleus (2012) 0.82
Proteomic approaches to understanding the role of the cytoskeleton in host-defense mechanisms. Expert Rev Proteomics (2011) 0.81
Cellular Levels of Signaling Factors Are Sensed by β-actin Alleles to Modulate Transcriptional Pulse Intensity. Cell Rep (2015) 0.80
Subnuclear compartmentalization and function of actin and nuclear myosin I in plants. Chromosoma (2008) 0.80
Fascin regulates nuclear actin during Drosophila oogenesis. Mol Biol Cell (2016) 0.77
Involvement of the SATB1/F-actin complex in chromatin reorganization during active cell death. Int J Mol Med (2014) 0.77
Human coronary artery smooth muscle cell responses to bioactive polyelectrolyte multilayer interfaces. Biotechnol Res Int (2010) 0.75
Three-dimensional apoptotic nuclear behavior analyzed by means of Field Emission in Lens Scanning Electron Microscope. Eur J Histochem (2015) 0.75
Actin-towards a deeper understanding of the relationship between tissue context, cellular function and tumorigenesis. Cancers (Basel) (2011) 0.75
Intermediate filaments: molecular structure, assembly mechanism, and integration into functionally distinct intracellular Scaffolds. Annu Rev Biochem (2004) 3.30
Intermediate filaments: from cell architecture to nanomechanics. Nat Rev Mol Cell Biol (2007) 2.95
The nanomechanical signature of breast cancer. Nat Nanotechnol (2012) 2.89
The nuclear pore complex: nucleocytoplasmic transport and beyond. Nat Rev Mol Cell Biol (2003) 2.77
Modular self-assembly of a Y-shaped multiprotein complex from seven nucleoporins. EMBO J (2002) 2.47
Nanomechanical basis of selective gating by the nuclear pore complex. Science (2007) 2.44
Dynamic elastic modulus of porcine articular cartilage determined at two different levels of tissue organization by indentation-type atomic force microscopy. Biophys J (2004) 2.20
Early detection of aging cartilage and osteoarthritis in mice and patient samples using atomic force microscopy. Nat Nanotechnol (2009) 2.19
Flexible phenylalanine-glycine nucleoporins as entropic barriers to nucleocytoplasmic transport. Proc Natl Acad Sci U S A (2006) 2.16
Lamin A/C-dependent localization of Nesprin-2, a giant scaffolder at the nuclear envelope. Mol Biol Cell (2005) 2.15
Multiple assembly pathways underlie amyloid-beta fibril polymorphisms. J Mol Biol (2005) 2.14
Cryo-electron tomography provides novel insights into nuclear pore architecture: implications for nucleocytoplasmic transport. J Mol Biol (2003) 2.05
Hrr25-dependent phosphorylation state regulates organization of the pre-40S subunit. Nature (2006) 1.95
Intermediate filaments: primary determinants of cell architecture and plasticity. J Clin Invest (2009) 1.88
Exploring the 3D molecular architecture of Escherichia coli type 1 pili. J Mol Biol (2002) 1.81
Domain-specific antibodies reveal multiple-site topology of Nup153 within the nuclear pore complex. J Struct Biol (2002) 1.76
Conserved segments 1A and 2B of the intermediate filament dimer: their atomic structures and role in filament assembly. EMBO J (2002) 1.73
Proteolytic E-cadherin activation followed by solution NMR and X-ray crystallography. EMBO J (2004) 1.69
The S. cerevisiae HtrA-like protein Nma111p is a nuclear serine protease that mediates yeast apoptosis. J Cell Sci (2004) 1.62
Vimentin organization modulates the formation of lamellipodia. Mol Biol Cell (2011) 1.60
The parallel superpleated beta-structure as a model for amyloid fibrils of human amylin. J Mol Biol (2005) 1.56
The nuclear pore complex: a jack of all trades? Trends Biochem Sci (2004) 1.55
A nonadjuvanted polypeptide nanoparticle vaccine confers long-lasting protection against rodent malaria. J Immunol (2009) 1.50
Actin in the nucleus: what form and what for? J Struct Biol (2002) 1.46
Towards reconciling structure and function in the nuclear pore complex. Histochem Cell Biol (2008) 1.45
Full-length rat amylin forms fibrils following substitution of single residues from human amylin. J Mol Biol (2003) 1.44
The biology of desmin filaments: how do mutations affect their structure, assembly, and organisation? J Struct Biol (2004) 1.42
Crystal structure of the human lamin A coil 2B dimer: implications for the head-to-tail association of nuclear lamins. J Mol Biol (2004) 1.42
Molecular architecture of intermediate filaments. Bioessays (2003) 1.40
Towards a molecular description of intermediate filament structure and assembly. Exp Cell Res (2007) 1.38
Nuclear actin extends, with no contraction in sight. Mol Biol Cell (2005) 1.36
Towards an integrated understanding of the structure and mechanics of the cell nucleus. Bioessays (2008) 1.35
A pre-ribosome with a tadpole-like structure functions in ATP-dependent maturation of 60S subunits. Mol Cell (2004) 1.34
Molecular and biophysical characterization of assembly-starter units of human vimentin. J Mol Biol (2004) 1.33
Human amylin oligomer growth and fibril elongation define two distinct phases in amyloid formation. J Biol Chem (2004) 1.33
Structure-based design of peptides that self-assemble into regular polyhedral nanoparticles. Nanomedicine (2006) 1.32
Severe muscle disease-causing desmin mutations interfere with in vitro filament assembly at distinct stages. Proc Natl Acad Sci U S A (2005) 1.30
Tensile properties of single desmin intermediate filaments. Biophys J (2008) 1.28
Functional complexity of intermediate filament cytoskeletons: from structure to assembly to gene ablation. Int Rev Cytol (2003) 1.28
Micro- and nanomechanical analysis of articular cartilage by indentation-type atomic force microscopy: validation with a gel-microfiber composite. Biophys J (2010) 1.26
Sac3 is an mRNA export factor that localizes to cytoplasmic fibrils of nuclear pore complex. Mol Biol Cell (2003) 1.26
A quantitative kinetic model for the in vitro assembly of intermediate filaments from tetrameric vimentin. J Biol Chem (2007) 1.25
Extracellular S100A1 protein inhibits apoptosis in ventricular cardiomyocytes via activation of the extracellular signal-regulated protein kinase 1/2 (ERK1/2). J Biol Chem (2003) 1.25
The highly conserved nuclear lamin Ig-fold binds to PCNA: its role in DNA replication. J Cell Biol (2008) 1.24
Isolation, characterization, and in vitro assembly of intermediate filaments. Methods Cell Biol (2004) 1.23
Nucleation and propagation of the collagen triple helix in single-chain and trimerized peptides: transition from third to first order kinetics. J Mol Biol (2002) 1.21
Self-assembly of human MxA GTPase into highly ordered dynamin-like oligomers. J Biol Chem (2002) 1.21
Myomesin is a molecular spring with adaptable elasticity. J Mol Biol (2005) 1.21
Structural analysis of a metazoan nuclear pore complex reveals a fused concentric ring architecture. J Mol Biol (2009) 1.19
Laminopathic mutations interfere with the assembly, localization, and dynamics of nuclear lamins. Proc Natl Acad Sci U S A (2007) 1.17
Substitutions in woolly mammoth hemoglobin confer biochemical properties adaptive for cold tolerance. Nat Genet (2010) 1.17
The core of tau-paired helical filaments studied by scanning transmission electron microscopy and limited proteolysis. Biochemistry (2006) 1.16
Ca2+ -dependent interaction of S100A1 with F1-ATPase leads to an increased ATP content in cardiomyocytes. Mol Cell Biol (2007) 1.16
The nanomechanical properties of rat fibroblasts are modulated by interfering with the vimentin intermediate filament system. J Struct Biol (2011) 1.14
Localization of uroplakin Ia, the urothelial receptor for bacterial adhesin FimH, on the six inner domains of the 16 nm urothelial plaque particle. J Mol Biol (2002) 1.14
Monitoring intermediate filament assembly by small-angle x-ray scattering reveals the molecular architecture of assembly intermediates. Proc Natl Acad Sci U S A (2006) 1.13
Characterization of early assembly intermediates of recombinant human keratins. J Struct Biol (2002) 1.12
Vimentin coil 1A-A molecular switch involved in the initiation of filament elongation. J Mol Biol (2009) 1.10
Lamin A and lamin C form homodimers and coexist in higher complex forms both in the nucleoplasmic fraction and in the lamina of cultured human cells. Nucleus (2011) 1.10
The supramolecular organization of the C. elegans nuclear lamin filament. J Mol Biol (2008) 1.10
Atomic structure of the vimentin central α-helical domain and its implications for intermediate filament assembly. Proc Natl Acad Sci U S A (2012) 1.10
Characterization of the head-to-tail overlap complexes formed by human lamin A, B1 and B2 "half-minilamin" dimers. J Mol Biol (2009) 1.10
Atomic structure of vimentin coil 2. J Struct Biol (2010) 1.07
Distinct subcellular location of the Ca2+-binding protein S100A1 differentially modulates Ca2+-cycling in ventricular rat cardiomyocytes. J Cell Sci (2005) 1.06
From the trap to the basket: getting to the bottom of the nuclear pore complex. Chromosoma (2006) 1.06
Peptide nanoparticles serve as a powerful platform for the immunogenic display of poorly antigenic actin determinants. J Mol Biol (2008) 1.05
Structure of zinc-independent sorbitol dehydrogenase from Rhodobacter sphaeroides at 2.4 A resolution. Acta Crystallogr D Biol Crystallogr (2005) 1.05
The use of coiled-coil proteins in drug delivery systems. Eur J Pharmacol (2009) 1.01
Dissecting the 3-D structure of vimentin intermediate filaments by cryo-electron tomography. J Struct Biol (2006) 1.00
Design and crystal structure of bacteriophage T4 mini-fibritin NCCF. J Mol Biol (2004) 0.99
Amyloid structure and assembly: insights from scanning transmission electron microscopy. J Struct Biol (2010) 0.98
Investigating native coronary artery endothelium in situ and in cell culture by scanning force microscopy. J Struct Biol (2005) 0.97
Impact of disease mutations on the desmin filament assembly process. J Mol Biol (2006) 0.97
Storage function of cartilage oligomeric matrix protein: the crystal structure of the coiled-coil domain in complex with vitamin D(3). EMBO J (2002) 0.97
The vertebrate nuclear pore complex: from structure to function. Results Probl Cell Differ (2002) 0.96
Solubility properties and specific assembly pathways of the B-type lamin from Caenorhabditis elegans. J Struct Biol (2006) 0.96
FHOD1 is a combined actin filament capping and bundling factor that selectively associates with actin arcs and stress fibers. J Cell Sci (2013) 0.96
Activation of muscle-specific receptor tyrosine kinase and binding to dystroglycan are regulated by alternative mRNA splicing of agrin. J Biol Chem (2006) 0.95
Actin's propensity for dynamic filament patterning. FEBS Lett (2002) 0.95
What transmission electron microscopes can visualize now and in the future. J Struct Biol (2008) 0.95
Removing an interhelical salt bridge abolishes coiled-coil formation in a de novo designed peptide. J Struct Biol (2002) 0.94
Polymerisation of chemically cross-linked actin:thymosin beta(4) complex to filamentous actin: alteration in helical parameters and visualisation of thymosin beta(4) binding on F-actin. J Mol Biol (2002) 0.94
Functional characterization of the human α-cardiac actin mutations Y166C and M305L involved in hypertrophic cardiomyopathy. Cell Mol Life Sci (2012) 0.94
Ataxin-10 interacts with O-linked beta-N-acetylglucosamine transferase in the brain. J Biol Chem (2006) 0.94
Complex formation and kinetics of filament assembly exhibited by the simple epithelial keratins K8 and K18. J Struct Biol (2011) 0.94
Developing scanning probe-based nanodevices--stepping out of the laboratory into the clinic. Nanomedicine (2007) 0.93
Recessive and dominant mutations in COL12A1 cause a novel EDS/myopathy overlap syndrome in humans and mice. Hum Mol Genet (2013) 0.93
Molecular mechanisms underlying the assembly of intermediate filaments. Exp Cell Res (2004) 0.93
From the polymorphism of amyloid fibrils to their assembly mechanism and cytotoxicity. Adv Protein Chem (2006) 0.93
Sequence comparisons of intermediate filament chains: evidence of a unique functional/structural role for coiled-coil segment 1A and linker L1. J Struct Biol (2002) 0.93
Nano-structure of the laminin γ-1 short arm reveals an extended and curved multidomain assembly. Matrix Biol (2010) 0.93
The single nuclear lamin of Caenorhabditis elegans forms in vitro stable intermediate filaments and paracrystals with a reduced axial periodicity. J Mol Biol (2003) 0.93
Nanomechanical interactions of phenylalanine-glycine nucleoporins studied by single molecule force-volume spectroscopy. J Struct Biol (2007) 0.92
Binding of G-quadruplexes to the N-terminal recognition domain of the RNA helicase associated with AU-rich element (RHAU). J Biol Chem (2013) 0.92