Published in Am J Physiol Heart Circ Physiol on May 25, 2007
Pathway analysis of seven common diseases assessed by genome-wide association. Genomics (2008) 4.11
Role for miR-204 in human pulmonary arterial hypertension. J Exp Med (2011) 2.60
The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure. Nat Med (2010) 1.84
Interleukin 6 knockout prevents angiotensin II hypertension: role of renal vasoconstriction and janus kinase 2/signal transducer and activator of transcription 3 activation. Hypertension (2010) 1.54
Signal transducers and activators of transcription-3/pim1 axis plays a critical role in the pathogenesis of human pulmonary arterial hypertension. Circulation (2011) 1.33
JAK redux: a second look at the regulation and role of JAKs in the heart. Am J Physiol Heart Circ Physiol (2009) 1.11
STAT3 signaling in pulmonary arterial hypertension. JAKSTAT (2012) 1.04
Signal transduction in the development of pulmonary arterial hypertension. Pulm Circ (2013) 0.95
Krüppel-like factor 5 contributes to pulmonary artery smooth muscle proliferation and resistance to apoptosis in human pulmonary arterial hypertension. Respir Res (2011) 0.95
Inflammation in diabetic kidney disease. World J Diabetes (2014) 0.91
Vascular remodeling process in pulmonary arterial hypertension, with focus on miR-204 and miR-126 (2013 Grover Conference series). Pulm Circ (2014) 0.90
Angiotensin II utilizes Janus kinase 2 in hypertension, but not in the physiological control of blood pressure, during low-salt intake. Am J Physiol Regul Integr Comp Physiol (2011) 0.89
Epigenetics: novel mechanism of pulmonary hypertension. Lung (2013) 0.82
Targeted inhibition of STATs and IRFs as a potential treatment strategy in cardiovascular disease. Oncotarget (2016) 0.81
Pulmonary extra-medullary hematopoiesis and pulmonary hypertension from underlying polycythemia vera: a case series. Pulm Circ (2017) 0.76
Interplay between endothelin and erythropoietin in astroglia: the role in protection against hypoxia. Int J Mol Sci (2014) 0.75
Myocardial Hypertrophic Remodeling and Impaired Left Ventricular Function in Mice with a Cardiac-Specific Deletion of Janus Kinase 2. Am J Pathol (2015) 0.75
Diabetic Microvascular Disease and Pulmonary Fibrosis: The Contribution of Platelets and Systemic Inflammation. Int J Mol Sci (2016) 0.75
Tissue specific dysregulated protein subnetworks in type 2 diabetic bladder urothelium and detrusor muscle. Mol Cell Proteomics (2015) 0.75
Podocyte-specific JAK2 overexpression worsens diabetic kidney disease in mice. Kidney Int (2017) 0.75
An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-sensitive hypertension. Hypertension (2005) 2.76
Soluble epoxide hydrolase inhibition protects the kidney from hypertension-induced damage. J Am Soc Nephrol (2004) 2.59
Regulation of blood pressure and salt homeostasis by endothelin. Physiol Rev (2011) 2.22
Association of telemedicine for remote monitoring of intensive care patients with mortality, complications, and length of stay. JAMA (2009) 2.14
Cullin-3 regulates vascular smooth muscle function and arterial blood pressure via PPARγ and RhoA/Rho-kinase. Cell Metab (2012) 1.99
Novel mechanism of activation of NADPH oxidase 5. calcium sensitization via phosphorylation. J Biol Chem (2006) 1.90
Paradoxical activation of endothelial nitric oxide synthase by NADPH oxidase. Arterioscler Thromb Vasc Biol (2008) 1.90
Targets for vascular protection after acute ischemic stroke. Stroke (2004) 1.88
Tumor necrosis factor alpha blockade increases renal Cyp2c23 expression and slows the progression of renal damage in salt-sensitive hypertension. Hypertension (2006) 1.77
Contrasting actions of endothelin ET(A) and ET(B) receptors in cardiovascular disease. Annu Rev Pharmacol Toxicol (2007) 1.74
TNF-alpha inhibition reduces renal injury in DOCA-salt hypertensive rats. Am J Physiol Regul Integr Comp Physiol (2007) 1.73
Protein tyrosine phosphatase 1B, a major regulator of leptin-mediated control of cardiovascular function. Circulation (2009) 1.70
Endothelin A receptor blockade reduces diabetic renal injury via an anti-inflammatory mechanism. J Am Soc Nephrol (2006) 1.63
An epoxide hydrolase inhibitor, 12-(3-adamantan-1-yl-ureido)dodecanoic acid (AUDA), reduces ischemic cerebral infarct size in stroke-prone spontaneously hypertensive rats. J Cardiovasc Pharmacol (2005) 1.59
Peroxisome proliferator-activated receptor-alpha activation reduces salt-dependent hypertension during chronic endothelin B receptor blockade. Hypertension (2005) 1.56
Hypertension in mice with transgenic activation of the brain renin-angiotensin system is vasopressin dependent. Am J Physiol Regul Integr Comp Physiol (2013) 1.56
VEGF differentially activates STAT3 in microvascular endothelial cells. FASEB J (2003) 1.53
Endothelin activation of reactive oxygen species mediates stress-induced pressor response in Dahl salt-sensitive prehypertensive rats. Hypertension (2010) 1.49
Fructose feeding increases insulin resistance but not blood pressure in Sprague-Dawley rats. Hypertension (2005) 1.49
Decreased endothelin binding and [Ca2+]i signaling in microvessels of DOCA-salt hypertensive rats. J Hypertens (2002) 1.46
Inhibition of the Jak/STAT signaling pathway prevents the high glucose-induced increase in tgf-beta and fibronectin synthesis in mesangial cells. Diabetes (2002) 1.42
Adaptive cerebral neovascularization in a model of type 2 diabetes: relevance to focal cerebral ischemia. Diabetes (2009) 1.40
Sex and sex hormones influence the development of albuminuria and renal macrophage infiltration in spontaneously hypertensive rats. Am J Physiol Regul Integr Comp Physiol (2007) 1.35
Angiotensin II activation of the JAK/STAT pathway in mesangial cells is altered by high glucose. Kidney Int (2002) 1.31
NADPH oxidase inhibition attenuates oxidative stress but not hypertension produced by chronic ET-1. Hypertension (2004) 1.31
Endothelin-1 increases glomerular permeability and inflammation independent of blood pressure in the rat. Hypertension (2010) 1.30
Renal medullary ETB receptors produce diuresis and natriuresis via NOS1. Am J Physiol Renal Physiol (2008) 1.29
Contribution of endothelin A receptors in endothelin 1-dependent natriuresis in female rats. Hypertension (2008) 1.28
Endothelin mediates superoxide production and vasoconstriction through activation of NADPH oxidase and uncoupled nitric-oxide synthase in the rat aorta. J Pharmacol Exp Ther (2005) 1.28
Angiotensin II blockade prevents hyperglycemia-induced activation of JAK and STAT proteins in diabetic rat kidney glomeruli. Am J Physiol Renal Physiol (2003) 1.27
Glutamate receptor expression in multiple sclerosis lesions. Brain Pathol (2007) 1.26
Renal endothelin in chronic angiotensin II hypertension. Am J Physiol Regul Integr Comp Physiol (2002) 1.24
Collecting duct-derived endothelin regulates arterial pressure and Na excretion via nitric oxide. Hypertension (2008) 1.24
Decreased renal cytochrome P450 2C enzymes and impaired vasodilation are associated with angiotensin salt-sensitive hypertension. Hypertension (2002) 1.24
Spironolactone improves structure and increases tone in the cerebral vasculature of male spontaneously hypertensive stroke-prone rats. Microvasc Res (2007) 1.23
Novel use of ultrasound to examine regional blood flow in the mouse kidney. Am J Physiol Renal Physiol (2009) 1.21
Early life stress sensitizes rats to angiotensin II-induced hypertension and vascular inflammation in adult life. Hypertension (2009) 1.21
Janus kinase 2, an early target of alpha 7 nicotinic acetylcholine receptor-mediated neuroprotection against Abeta-(1-42) amyloid. J Biol Chem (2002) 1.21
Alpha7 nicotinic receptors as novel therapeutic targets for inflammation-based diseases. Cell Mol Life Sci (2010) 1.20
Cytochrome c oxidase subunit IV as a marker of protein kinase Cepsilon function in neonatal cardiac myocytes: implications for cytochrome c oxidase activity. Biochem J (2004) 1.18
Hypertension after experimental cerebral ischemia: candesartan provides neurovascular protection. J Hypertens (2006) 1.17
Prevalent diagnosed HIV in England, Wales and Northern Ireland: adjusted totals 1996 to 2001 and extrapolations to 2004. AIDS (2004) 1.16
Flow regulation of collecting duct endothelin-1 production. Am J Physiol Renal Physiol (2010) 1.15
Low-flow vascular remodeling in the metabolic syndrome X. Am J Physiol Heart Circ Physiol (2003) 1.14
Deletion of protein tyrosine phosphatase 1b improves peripheral insulin resistance and vascular function in obese, leptin-resistant mice via reduced oxidant tone. Circ Res (2009) 1.13
Role of endothelin-1 in clinical hypertension: 20 years on. Hypertension (2008) 1.13
Vascular protection in diabetic stroke: role of matrix metalloprotease-dependent vascular remodeling. J Cereb Blood Flow Metab (2010) 1.10
Chemokine receptor 2b inhibition provides renal protection in angiotensin II - salt hypertension. Hypertension (2007) 1.10
Neurovascular injury in acute hyperglycemia and diabetes: A comparative analysis in experimental stroke. Transl Stroke Res (2011) 1.08
Physiology of endothelin and the kidney. Compr Physiol (2011) 1.08
Functional role of ETB receptors in the renal medulla. Hypertension (2003) 1.08
Renal collecting duct NOS1 maintains fluid-electrolyte homeostasis and blood pressure. Hypertension (2013) 1.07
Sex-independent neuroprotection with minocycline after experimental thromboembolic stroke. Exp Transl Stroke Med (2011) 1.07
Exaggerated cardiovascular stress responses and impaired beta-adrenergic-mediated pressor recovery in obese Zucker rats. Hypertension (2006) 1.07
Gender differences in ET and NOS systems in ETB receptor-deficient rats: effect of a high salt diet. Hypertension (2002) 1.06
Sex differences in renal medullary endothelin receptor function in angiotensin II hypertensive rats. Hypertension (2011) 1.06
Activation of the JAK/STAT pathway in vascular smooth muscle by serotonin. Am J Physiol Cell Physiol (2004) 1.05
Salt-sensitive hypertension after exposure to angiotensin is associated with inability to upregulate renal epoxygenases. Hypertension (2003) 1.05
S100B-RAGE-mediated augmentation of angiotensin II-induced activation of JAK2 in vascular smooth muscle cells is dependent on PLD2. Diabetes (2003) 1.04
Effect of simvastatin on high glucose- and angiotensin II-induced activation of the JAK/STAT pathway in mesangial cells. Am J Physiol Renal Physiol (2006) 1.03
Arterial pressure response to the antioxidant tempol and ETB receptor blockade in rats on a high-salt diet. Hypertension (2004) 1.03
Protective role of extracellular superoxide dismutase in renal ischemia/reperfusion injury. Kidney Int (2010) 1.02
Aldose reductase pathway mediates JAK-STAT signaling: a novel axis in myocardial ischemic injury. FASEB J (2005) 1.02
Altered nitric oxide synthase 3 distribution in mesenteric arteries of hypertensive rats. Hypertension (2002) 1.01
Distinct actions of endothelin A-selective versus combined endothelin A/B receptor antagonists in early diabetic kidney disease. J Pharmacol Exp Ther (2011) 1.01
Tactics for vascular protection after acute ischemic stroke. Pharmacotherapy (2005) 1.01
Insulin resistance does not diminish eNOS expression, phosphorylation, or binding to HSP-90. Am J Physiol Heart Circ Physiol (2004) 1.00
Comparison of gene expression during preimplantation development between diploid and haploid mouse embryos. Biol Reprod (2002) 1.00
Reduced NOS3 phosphorylation mediates reduced NO/cGMP signaling in mesenteric arteries of deoxycorticosterone acetate-salt hypertensive rats. Hypertension (2004) 0.99
Endothelin antagonists for diabetic and non-diabetic chronic kidney disease. Br J Clin Pharmacol (2013) 0.99
Attenuated vasoconstrictor responses to endothelin in afferent arterioles during a high-salt diet. Am J Physiol Renal Physiol (2007) 0.98
Endothelin antagonism prevents early EGFR transactivation but not increased matrix metalloproteinase activity in diabetes. Am J Physiol Regul Integr Comp Physiol (2005) 0.97
High glucose augments the angiotensin II-induced activation of JAK2 in vascular smooth muscle cells via the polyol pathway. J Biol Chem (2003) 0.97
Early life stress downregulates endothelin receptor expression and enhances acute stress-mediated blood pressure responses in adult rats. Am J Physiol Regul Integr Comp Physiol (2010) 0.97
Extracellular signal-regulated kinase 1/2 activation, via downregulation of mitogen-activated protein kinase phosphatase 1, mediates sex differences in desoxycorticosterone acetate-salt hypertension vascular reactivity. Hypertension (2009) 0.97
ETA and ETB receptors differentially modulate afferent and efferent arteriolar responses to endothelin. Br J Pharmacol (2005) 0.97
Endothelin, kidney disease, and hypertension. Hypertension (2013) 0.97
O-GlcNAcylation contributes to augmented vascular reactivity induced by endothelin 1. Hypertension (2009) 0.96
Plasma endothelin-1 release during acute stress: role of ethnicity and sex. Psychosom Med (2002) 0.96
Endothelin and NOS1/nitric oxide signaling and regulation of sodium homeostasis. Curr Opin Nephrol Hypertens (2008) 0.95
Loss of renal medullary endothelin B receptor function during salt deprivation is regulated by angiotensin II. Am J Physiol Renal Physiol (2012) 0.95
Superoxide-dependent hypertension in male and female endothelin B receptor-deficient rats. Exp Biol Med (Maywood) (2006) 0.94
Endothelin ET(B) receptors contribute to sex differences in blood pressure elevation in angiotensin II hypertensive rats on a high-salt diet. Clin Exp Pharmacol Physiol (2013) 0.94
Ensuring patient safety in care transitions: an empirical evaluation of a Handoff Intervention Tool. AMIA Annu Symp Proc (2012) 0.93
Falling through the cracks: information breakdowns in critical care handoff communication. AMIA Annu Symp Proc (2011) 0.93
Unique endothelin receptor binding in kidneys of ETB receptor deficient rats. Am J Physiol Regul Integr Comp Physiol (2003) 0.93
Selective and mixed endothelin receptor antagonism in cardiovascular disease. Trends Pharmacol Sci (2007) 0.93
Altered kidney CYP2C and cyclooxygenase-2 levels are associated with obesity-related albuminuria. Obes Res (2004) 0.93
Expression of genes encoding chromatin regulatory factors in developing rhesus monkey oocytes and preimplantation stage embryos: possible roles in genome activation. Biol Reprod (2004) 0.92
Dissecting the genetic architecture of the cardiovascular and renal stress response. Biol Psychol (2002) 0.92
ETA receptor blockade attenuates hypertension and decreases reactive oxygen species in ETB receptor-deficient rats. J Cardiovasc Pharmacol (2004) 0.92
Posttranslational regulation of NO synthase activity in the renal medulla of diabetic rats. Am J Physiol Renal Physiol (2004) 0.92
The primate embryo gene expression resource: a novel resource to facilitate rapid analysis of gene expression patterns in non-human primate oocytes and preimplantation stage embryos. Biol Reprod (2004) 0.92
Immunosuppression with mycophenolate mofetil attenuates the development of hypertension and albuminuria in deoxycorticosterone acetate-salt hypertensive rats. Clin Exp Pharmacol Physiol (2010) 0.92
Impaired insulin-mediated vasorelaxation in a nonobese model of type 2 diabetes: role of endothelin-1. Can J Physiol Pharmacol (2008) 0.92
Sexual dimorphism in renal production of prostanoids in spontaneously hypertensive rats. Hypertension (2005) 0.91
Acute increases of renal medullary osmolality stimulate endothelin release from the kidney. Am J Physiol Renal Physiol (2006) 0.91