Published in Stroke on July 29, 2004
Inflammatory mechanisms in ischemic stroke: role of inflammatory cells. J Leukoc Biol (2010) 4.37
Collateral flow predicts response to endovascular therapy for acute ischemic stroke. Stroke (2011) 2.80
Signaling and functions of angiopoietin-1 in vascular protection. Circ Res (2006) 2.34
Brain angiogenesis in developmental and pathological processes: neurovascular injury and angiogenic recovery after stroke. FEBS J (2009) 1.82
Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes. J Extracell Vesicles (2012) 1.81
Delayed minocycline inhibits ischemia-activated matrix metalloproteinases 2 and 9 after experimental stroke. BMC Neurosci (2006) 1.69
Blood-brain barrier dysfunction as a cause and consequence of Alzheimer's disease. J Cereb Blood Flow Metab (2013) 1.45
Human neural stem cells over-expressing VEGF provide neuroprotection, angiogenesis and functional recovery in mouse stroke model. PLoS One (2007) 1.41
Increased hemorrhagic transformation and altered infarct size and localization after experimental stroke in a rat model type 2 diabetes. BMC Neurol (2007) 1.41
Biphasic actions of HMGB1 signaling in inflammation and recovery after stroke. Ann N Y Acad Sci (2010) 1.39
HIF-1alpha inhibition ameliorates neonatal brain injury in a rat pup hypoxic-ischemic model. Neurobiol Dis (2008) 1.28
Protecting against cerebrovascular injury: contributions of 12/15-lipoxygenase to edema formation after transient focal ischemia. Stroke (2008) 1.25
Mmp-9 inhibition: a therapeutic strategy in ischemic stroke. Mol Neurobiol (2013) 1.22
Hyperglycemia, diabetes and stroke: focus on the cerebrovasculature. Vascul Pharmacol (2009) 1.14
Hypoxic preconditioning-induced cerebral ischemic tolerance: role of microvascular sphingosine kinase 2. Stroke (2009) 1.11
Effect of neutrophil depletion on gelatinase expression, edema formation and hemorrhagic transformation after focal ischemic stroke. BMC Neurosci (2005) 1.11
The interleukin-8 (IL-8/CXCL8) receptor inhibitor reparixin improves neurological deficits and reduces long-term inflammation in permanent and transient cerebral ischemia in rats. Mol Med (2007) 1.11
Vascular protection by angiotensin receptor antagonism involves differential VEGF expression in both hemispheres after experimental stroke. PLoS One (2011) 1.10
Cellular mechanisms of neurovascular damage and repair after stroke. J Child Neurol (2011) 1.05
Stroke-induced brain parenchymal injury drives blood-brain barrier early leakage kinetics: a combined in vivo/in vitro study. J Cereb Blood Flow Metab (2013) 1.02
Intracerebral hemorrhage leads to infiltration of several leukocyte populations with concomitant pathophysiological changes. J Cereb Blood Flow Metab (2008) 0.99
Early atorvastatin reduces hemorrhage after acute cerebral ischemia in diabetic rats. J Pharmacol Exp Ther (2009) 0.99
Inhibition of NF-kappaB activation by 5-lipoxygenase inhibitors protects brain against injury in a rat model of focal cerebral ischemia. J Neuroinflammation (2006) 0.99
Biphasic mechanisms of neurovascular unit injury and protection in CNS diseases. CNS Neurol Disord Drug Targets (2013) 0.98
Nox2 oxidase activity accounts for the oxidative stress and vasomotor dysfunction in mouse cerebral arteries following ischemic stroke. PLoS One (2011) 0.94
Beneficial effects of mood stabilizers lithium, valproate and lamotrigine in experimental stroke models. Acta Pharmacol Sin (2011) 0.93
Baicalin inhibits TLR2/4 signaling pathway in rat brain following permanent cerebral ischemia. Inflammation (2011) 0.92
Non-coding RNAs in cerebral endothelial pathophysiology: emerging roles in stroke. Neurochem Int (2014) 0.92
Age-related comparisons of evolution of the inflammatory response after intracerebral hemorrhage in rats. Transl Stroke Res (2012) 0.89
Transient focal cerebral ischemia induces long-term cerebral vasculature dysfunction in a rodent experimental stroke model. Transl Stroke Res (2012) 0.88
Crosstalk between cerebral endothelium and oligodendrocyte. Cell Mol Life Sci (2013) 0.86
AM-36 modulates the neutrophil inflammatory response and reduces breakdown of the blood brain barrier after endothelin-1 induced focal brain ischaemia. Br J Pharmacol (2006) 0.86
Endothelial progenitor cells: therapeutic perspective for ischemic stroke. CNS Neurosci Ther (2012) 0.86
Contribution of nitric oxide synthase (NOS) activity in blood-brain barrier disruption and edema after acute ischemia/reperfusion in aortic coarctation-induced hypertensive rats. Iran Biomed J (2011) 0.86
In vivo quantification of transvascular water exchange during the acute phase of permanent stroke. Magn Reson Med (2008) 0.85
Drug repurposing for vascular protection after acute ischemic stroke. Acta Neurochir Suppl (2011) 0.84
Induction of vascular endothelial growth factor and matrix metalloproteinase-9 via CD47 signaling in neurovascular cells. Neurochem Res (2010) 0.83
Docosahexaenoic acid improves behavior and attenuates blood-brain barrier injury induced by focal cerebral ischemia in rats. Exp Transl Stroke Med (2015) 0.83
Sequential Therapy with Minocycline and Candesartan Improves Long-Term Recovery After Experimental Stroke. Transl Stroke Res (2015) 0.83
Altered long non-coding RNA transcriptomic profiles in brain microvascular endothelium after cerebral ischemia. Exp Neurol (2015) 0.82
Altered reactivity of tertiary mesenteric arteries following acute myocardial ischemia. J Vasc Res (2012) 0.81
A Pilot Study for the Neuroprotective Effect of Gongjin-dan on Transient Middle Cerebral Artery Occlusion-Induced Ischemic Rat Brain. Evid Based Complement Alternat Med (2012) 0.80
Blood-brain barrier dysfunction in epileptogenesis of the temporal lobe. Epilepsy Res Treat (2011) 0.80
Sustained mitochondrial functioning in cerebral arteries after transient ischemic stress in the rat: a potential target for therapies. Am J Physiol Heart Circ Physiol (2014) 0.80
Angiopoietin-1 is associated with cerebral vasospasm and delayed cerebral ischemia in subarachnoid hemorrhage. BMC Neurol (2011) 0.80
Role of matrix metalloproteinase activity in the neurovascular protective effects of Angiotensin antagonism. Stroke Res Treat (2014) 0.78
The Role of Monocytes in Ischemic Stroke Pathobiology: New Avenues to Explore. Front Aging Neurosci (2016) 0.77
Elevated Aminopeptidase P Attenuates Cerebral Arterial Responses to Bradykinin in Fawn-Hooded Hypertensive Rats. PLoS One (2015) 0.77
The role of the neuro-astro-vascular unit in the etiology of ataxia telangiectasia. Front Pharmacol (2012) 0.77
12/15-Lipoxygenase Inhibition or Knockout Reduces Warfarin-Associated Hemorrhagic Transformation After Experimental Stroke. Stroke (2017) 0.76
Modulating Astrocyte Transition after Stroke to Promote Brain Rescue and Functional Recovery: Emerging Targets Include Rho Kinase. Int J Mol Sci (2016) 0.76
Loss of Integrity: Impairment of the Blood-brain Barrier in Heavy Metal-associated Ischemic Stroke. Toxicol Res (2013) 0.76
Critical role of sphingosine-1-phosphate receptor-2 in the disruption of cerebrovascular integrity in experimental stroke. Nat Commun (2015) 0.76
Enhanced anti-ischemic stroke of ZL006 by T7-conjugated PEGylated liposomes drug delivery system. Sci Rep (2015) 0.75
Role of Transporters in Central Nervous System Drug Delivery and Blood-Brain Barrier Protection: Relevance to Treatment of Stroke. J Cent Nerv Syst Dis (2017) 0.75
Krüpple-like factors in the central nervous system: novel mediators in stroke. Metab Brain Dis (2013) 0.75
Malvidin's Effects on Rat Pial Microvascular Permeability Changes Due to Hypoperfusion and Reperfusion Injury. Front Cell Neurosci (2016) 0.75
Chronic intracerebroventricular delivery of the secretory phospholipase A2 inhibitor, 12-epi-scalaradial, does not improve outcome after focal cerebral ischemia-reperfusion in rats. Exp Brain Res (2007) 0.75
Exploring the functional landscape of gene expression: directed search of large microarray compendia. Bioinformatics (2007) 3.59
Oxidative stress and the use of antioxidants in diabetes: linking basic science to clinical practice. Cardiovasc Diabetol (2005) 2.88
An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-sensitive hypertension. Hypertension (2005) 2.76
Soluble epoxide hydrolase inhibition protects the kidney from hypertension-induced damage. J Am Soc Nephrol (2004) 2.59
A simple, assumption-free, and clinically interpretable approach for analysis of modified Rankin outcomes. Stroke (2012) 2.57
Remote ischemic perconditioning is effective alone and in combination with intravenous tissue-type plasminogen activator in murine model of embolic stroke. Stroke (2012) 2.46
Regulation of blood pressure and salt homeostasis by endothelin. Physiol Rev (2011) 2.22
Remote evaluation of acute ischemic stroke: reliability of National Institutes of Health Stroke Scale via telestroke. Stroke (2003) 2.17
SDF-1 (CXCL12) is upregulated in the ischemic penumbra following stroke: association with bone marrow cell homing to injury. J Neuropathol Exp Neurol (2004) 1.94
Matrix metalloproteinase-9 in an exploratory trial of intravenous minocycline for acute ischemic stroke. Stroke (2011) 1.80
Minocycline up-regulates Bcl-2 and protects against cell death in mitochondria. J Biol Chem (2004) 1.79
Predicting gene function in a hierarchical context with an ensemble of classifiers. Genome Biol (2008) 1.78
Tumor necrosis factor alpha blockade increases renal Cyp2c23 expression and slows the progression of renal damage in salt-sensitive hypertension. Hypertension (2006) 1.77
Contrasting actions of endothelin ET(A) and ET(B) receptors in cardiovascular disease. Annu Rev Pharmacol Toxicol (2007) 1.74
Protein nitration impairs the myogenic tone of rat middle cerebral arteries in both ischemic and nonischemic hemispheres after ischemic stroke. Am J Physiol Heart Circ Physiol (2013) 1.74
Type 2 diabetes causes remodeling of cerebrovasculature via differential regulation of matrix metalloproteinases and collagen synthesis: role of endothelin-1. Diabetes (2005) 1.74
TNF-alpha inhibition reduces renal injury in DOCA-salt hypertensive rats. Am J Physiol Regul Integr Comp Physiol (2007) 1.73
Blood pressure lowering after experimental cerebral ischemia provides neurovascular protection. J Hypertens (2007) 1.71
Delayed minocycline inhibits ischemia-activated matrix metalloproteinases 2 and 9 after experimental stroke. BMC Neurosci (2006) 1.69
Minocycline to improve neurologic outcome in stroke (MINOS): a dose-finding study. Stroke (2010) 1.69
Endothelin A receptor blockade reduces diabetic renal injury via an anti-inflammatory mechanism. J Am Soc Nephrol (2006) 1.63
Who's in favor of translational cell therapy for stroke: STEPS forward please? Cell Transplant (2009) 1.60
An epoxide hydrolase inhibitor, 12-(3-adamantan-1-yl-ureido)dodecanoic acid (AUDA), reduces ischemic cerebral infarct size in stroke-prone spontaneously hypertensive rats. J Cardiovasc Pharmacol (2005) 1.59
Peroxisome proliferator-activated receptor-alpha activation reduces salt-dependent hypertension during chronic endothelin B receptor blockade. Hypertension (2005) 1.56
Improving modified Rankin Scale assessment with a simplified questionnaire. Stroke (2010) 1.50
Endothelin activation of reactive oxygen species mediates stress-induced pressor response in Dahl salt-sensitive prehypertensive rats. Hypertension (2010) 1.49
Fructose feeding increases insulin resistance but not blood pressure in Sprague-Dawley rats. Hypertension (2005) 1.49
Low dose intravenous minocycline is neuroprotective after middle cerebral artery occlusion-reperfusion in rats. BMC Neurol (2004) 1.47
Decreased endothelin binding and [Ca2+]i signaling in microvessels of DOCA-salt hypertensive rats. J Hypertens (2002) 1.46
Optimal delivery of minocycline to the brain: implication for human studies of acute neuroprotection. Exp Neurol (2004) 1.40
Adaptive cerebral neovascularization in a model of type 2 diabetes: relevance to focal cerebral ischemia. Diabetes (2009) 1.40
Bone marrow grafts restore cerebral blood flow and blood brain barrier in stroke rats. Brain Res (2004) 1.40
Pathophysiology and treatment of stroke in sickle-cell disease: present and future. Lancet Neurol (2006) 1.39
The neuroblast and angioblast chemotaxic factor SDF-1 (CXCL12) expression is briefly up regulated by reactive astrocytes in brain following neonatal hypoxic-ischemic injury. BMC Neurosci (2005) 1.38
Sex and sex hormones influence the development of albuminuria and renal macrophage infiltration in spontaneously hypertensive rats. Am J Physiol Regul Integr Comp Physiol (2007) 1.35
Rural-urban differences in acute stroke management practices: a modifiable disparity. Arch Neurol (2008) 1.33
Therapeutic targets and limits of minocycline neuroprotection in experimental ischemic stroke. BMC Neurosci (2009) 1.33
NADPH oxidase inhibition attenuates oxidative stress but not hypertension produced by chronic ET-1. Hypertension (2004) 1.31
Endothelin-1 increases glomerular permeability and inflammation independent of blood pressure in the rat. Hypertension (2010) 1.30
Minocycline and tissue-type plasminogen activator for stroke: assessment of interaction potential. Stroke (2009) 1.30
Renal medullary ETB receptors produce diuresis and natriuresis via NOS1. Am J Physiol Renal Physiol (2008) 1.29
Contribution of endothelin A receptors in endothelin 1-dependent natriuresis in female rats. Hypertension (2008) 1.28
Endothelin mediates superoxide production and vasoconstriction through activation of NADPH oxidase and uncoupled nitric-oxide synthase in the rat aorta. J Pharmacol Exp Ther (2005) 1.28
Angiotensin II blockade prevents hyperglycemia-induced activation of JAK and STAT proteins in diabetic rat kidney glomeruli. Am J Physiol Renal Physiol (2003) 1.27
Renal endothelin in chronic angiotensin II hypertension. Am J Physiol Regul Integr Comp Physiol (2002) 1.24
Decreased renal cytochrome P450 2C enzymes and impaired vasodilation are associated with angiotensin salt-sensitive hypertension. Hypertension (2002) 1.24
Collecting duct-derived endothelin regulates arterial pressure and Na excretion via nitric oxide. Hypertension (2008) 1.24
Minocycline for short-term neuroprotection. Pharmacotherapy (2006) 1.23
Spironolactone improves structure and increases tone in the cerebral vasculature of male spontaneously hypertensive stroke-prone rats. Microvasc Res (2007) 1.23
Candesartan augments ischemia-induced proangiogenic state and results in sustained improvement after stroke. Stroke (2009) 1.23
Intravenous grafts recapitulate the neurorestoration afforded by intracerebrally delivered multipotent adult progenitor cells in neonatal hypoxic-ischemic rats. J Cereb Blood Flow Metab (2008) 1.22
Novel use of ultrasound to examine regional blood flow in the mouse kidney. Am J Physiol Renal Physiol (2009) 1.21
Early life stress sensitizes rats to angiotensin II-induced hypertension and vascular inflammation in adult life. Hypertension (2009) 1.21
The impact of incomplete knowledge on evaluation: an experimental benchmark for protein function prediction. Bioinformatics (2009) 1.21
Directing experimental biology: a case study in mitochondrial biogenesis. PLoS Comput Biol (2009) 1.20
A telestroke network enhances recruitment into acute stroke clinical trials. Stroke (2010) 1.19
Simplified modified rankin scale questionnaire: reproducibility over the telephone and validation with quality of life. Stroke (2011) 1.19
Hypertension after experimental cerebral ischemia: candesartan provides neurovascular protection. J Hypertens (2006) 1.17
Teleneurology applications: Report of the Telemedicine Work Group of the American Academy of Neurology. Neurology (2013) 1.17
Hematopoietic origin of glomerular mesangial cells. Blood (2002) 1.17
Toward cell therapy using placenta-derived cells: disease mechanisms, cell biology, preclinical studies, and regulatory aspects at the round table. Stem Cells Dev (2010) 1.17
Cerebral myogenic reactivity and blood flow in type 2 diabetic rats: role of peroxynitrite in hypoxia-mediated loss of myogenic tone. J Pharmacol Exp Ther (2012) 1.15
Neural progenitor NT2N cell lines from teratocarcinoma for transplantation therapy in stroke. Prog Neurobiol (2008) 1.15
Flow regulation of collecting duct endothelin-1 production. Am J Physiol Renal Physiol (2010) 1.15
Low-flow vascular remodeling in the metabolic syndrome X. Am J Physiol Heart Circ Physiol (2003) 1.14
Angiotensin II and endothelin-1 augment the vascular complications of diabetes via JAK2 activation. Am J Physiol Heart Circ Physiol (2007) 1.14
Role of endothelin-1 in clinical hypertension: 20 years on. Hypertension (2008) 1.13
Potential of stem/progenitor cells in treating stroke: the missing steps in translating cell therapy from laboratory to clinic. Regen Med (2008) 1.13
Minocycline development for acute ischemic stroke. Transl Stroke Res (2011) 1.12
Vasoactive factors in sickle cell disease: in vitro evidence for endothelin-1-mediated vasoconstriction. Am J Hematol (2004) 1.11
Effect of chronic endothelin receptor antagonism on cerebrovascular function in type 2 diabetes. Am J Physiol Regul Integr Comp Physiol (2008) 1.11
Glycemic control prevents microvascular remodeling and increased tone in type 2 diabetes: link to endothelin-1. Am J Physiol Regul Integr Comp Physiol (2009) 1.11
Effect of neutrophil depletion on gelatinase expression, edema formation and hemorrhagic transformation after focal ischemic stroke. BMC Neurosci (2005) 1.11
Behavioral and histological characterization of intrahippocampal grafts of human bone marrow-derived multipotent progenitor cells in neonatal rats with hypoxic-ischemic injury. Cell Transplant (2006) 1.10
Vascular protection by angiotensin receptor antagonism involves differential VEGF expression in both hemispheres after experimental stroke. PLoS One (2011) 1.10
Vascular protection in diabetic stroke: role of matrix metalloprotease-dependent vascular remodeling. J Cereb Blood Flow Metab (2010) 1.10
Chemokine receptor 2b inhibition provides renal protection in angiotensin II - salt hypertension. Hypertension (2007) 1.10
A web-based telestroke system facilitates rapid treatment of acute ischemic stroke patients in rural emergency departments. J Emerg Med (2008) 1.09
Neurovascular injury in acute hyperglycemia and diabetes: A comparative analysis in experimental stroke. Transl Stroke Res (2011) 1.08
Physiology of endothelin and the kidney. Compr Physiol (2011) 1.08
Remote evaluation of acute ischemic stroke in rural community hospitals in Georgia. Stroke (2004) 1.08
Functional role of ETB receptors in the renal medulla. Hypertension (2003) 1.08
Targets of vascular protection in acute ischemic stroke differ in type 2 diabetes. Am J Physiol Heart Circ Physiol (2013) 1.07
Renal collecting duct NOS1 maintains fluid-electrolyte homeostasis and blood pressure. Hypertension (2013) 1.07
Sex-independent neuroprotection with minocycline after experimental thromboembolic stroke. Exp Transl Stroke Med (2011) 1.07
Exaggerated cardiovascular stress responses and impaired beta-adrenergic-mediated pressor recovery in obese Zucker rats. Hypertension (2006) 1.07
AT1 receptor antagonism is proangiogenic in the brain: BDNF a novel mediator. J Pharmacol Exp Ther (2012) 1.07
Gender differences in ET and NOS systems in ETB receptor-deficient rats: effect of a high salt diet. Hypertension (2002) 1.06
Sex differences in renal medullary endothelin receptor function in angiotensin II hypertensive rats. Hypertension (2011) 1.06
Evidence for a matrix metalloproteinase induction/activation system in arterial vasculature and decreased synthesis and activity in diabetes. Diabetes (2002) 1.05
Vascularization pattern after ischemic stroke is different in control versus diabetic rats: relevance to stroke recovery. Stroke (2013) 1.05