Published in J Pharmacol Exp Ther on September 06, 2005
Hydroethidine- and MitoSOX-derived red fluorescence is not a reliable indicator of intracellular superoxide formation: another inconvenient truth. Free Radic Biol Med (2010) 2.32
Chemistry and antihypertensive effects of tempol and other nitroxides. Pharmacol Rev (2008) 1.91
Contrasting actions of endothelin ET(A) and ET(B) receptors in cardiovascular disease. Annu Rev Pharmacol Toxicol (2007) 1.74
Endothelin A receptor blockade reduces diabetic renal injury via an anti-inflammatory mechanism. J Am Soc Nephrol (2006) 1.63
Redox signaling, vascular function, and hypertension. Antioxid Redox Signal (2008) 1.52
Endothelin activation of reactive oxygen species mediates stress-induced pressor response in Dahl salt-sensitive prehypertensive rats. Hypertension (2010) 1.49
ET-1 increases reactive oxygen species following hypoxia and high-salt diet in the mouse glomerulus. Acta Physiol (Oxf) (2014) 1.44
NOX in liver fibrosis. Arch Biochem Biophys (2007) 1.29
Matrix metalloproteinase 2-induced venous dilation via hyperpolarization and activation of K+ channels: relevance to varicose vein formation. J Vasc Surg (2007) 1.11
Targeted detoxification of selected reactive oxygen species in the vascular endothelium. J Pharmacol Exp Ther (2009) 1.11
Deletion of soluble epoxide hydrolase gene improves renal endothelial function and reduces renal inflammation and injury in streptozotocin-induced type 1 diabetes. Am J Physiol Regul Integr Comp Physiol (2011) 1.11
Hypertension: what's sex got to do with it? Physiology (Bethesda) (2013) 1.09
Long-term administration of endothelin receptor antagonist improves coronary endothelial function in patients with early atherosclerosis. Circulation (2010) 1.08
Central cardiovascular circuits contribute to the neurovascular dysfunction in angiotensin II hypertension. J Neurosci (2012) 1.06
Role of renal sensory nerves in physiological and pathophysiological conditions. Am J Physiol Regul Integr Comp Physiol (2014) 1.02
The mechanistic basis of arsenicosis: pathogenesis of skin cancer. Cancer Lett (2014) 0.99
Endothelin antagonists for diabetic and non-diabetic chronic kidney disease. Br J Clin Pharmacol (2013) 0.99
Reactive oxygen species are involved in regulating alpha1-adrenoceptor-activated vascular smooth muscle contraction. J Biomed Sci (2010) 0.98
Age-related changes in redox signaling and VSMC function. Antioxid Redox Signal (2010) 0.97
Kinin B1 receptor enhances the oxidative stress in a rat model of insulin resistance: outcome in hypertension, allodynia and metabolic complications. PLoS One (2010) 0.96
Comparison of inhibitors of superoxide generation in vascular smooth muscle cells. Br J Pharmacol (2009) 0.93
Bosentan inhibits oxidative and nitrosative stress and rescues occlusive pulmonary hypertension. Free Radic Biol Med (2012) 0.93
Circulating endothelin-1 alters critical mechanisms regulating cerebral microcirculation. Hypertension (2013) 0.90
Redox signaling in pathophysiology of hypertension. J Biomed Sci (2013) 0.90
Tempol, a superoxide dismutase mimetic, prevents cerebral vessel remodeling in hypertensive rats. Microvasc Res (2010) 0.89
The role of endothelin-1 and endothelin receptor antagonists in inflammatory response and sepsis. Arch Immunol Ther Exp (Warsz) (2014) 0.87
Synergistic actions of enalapril and tempol during chronic angiotensin II-induced hypertension. Vascul Pharmacol (2006) 0.86
Dietary sodium modulates the interaction between efferent renal sympathetic nerve activity and afferent renal nerve activity: role of endothelin. Am J Physiol Regul Integr Comp Physiol (2009) 0.86
A comparison of reactive oxygen species metabolism in the rat aorta and vena cava: focus on xanthine oxidase. Am J Physiol Heart Circ Physiol (2008) 0.83
Endothelial and Smooth Muscle Cell Interactions in the Pathobiology of Pulmonary Hypertension. Am J Respir Cell Mol Biol (2016) 0.81
Endothelin-1 but not angiotensin II contributes to functional aging in murine carotid arteries. Life Sci (2014) 0.81
Endothelin-1 contributes to the progression of renal injury in sickle cell disease via reactive oxygen species. Br J Pharmacol (2016) 0.79
Relationship of endothelin-1 and NLRP3 inflammasome activation in HT22 hippocampal cells in diabetes. Life Sci (2016) 0.79
Functional heterogeneity of NADPH oxidase-mediated contractions to endothelin with vascular aging. Life Sci (2013) 0.78
Endothelin-1 contributes to endothelial dysfunction and enhanced vasoconstriction through augmented superoxide production in penile arteries from insulin-resistant obese rats: role of ET(A) and ET(B) receptors. Br J Pharmacol (2014) 0.78
Isoproterenol-induced FKBP12.6/12 downregulation is modulated by ETA and ETB receptors and reversed by argirhein, a derivative of rhein. Acta Pharmacol Sin (2011) 0.77
Air Pollution-Induced Vascular Dysfunction: Potential Role of Endothelin-1 (ET-1) System. Cardiovasc Toxicol (2016) 0.76
Serum Concentrations of Endothelin-1 and Matrix Metalloproteinases-2, -9 in Pre-Hypertensive and Hypertensive Patients with Type 2 Diabetes. Int J Mol Sci (2016) 0.75
Endothelin-1 shifts the mediator of bradykinin-induced relaxation from NO to H2 O2 in resistance arteries from patients with cardiovascular disease. Br J Pharmacol (2016) 0.75
Dahl SS rats demonstrate enhanced aortic perivascular adipose tissue-mediated buffering of vasoconstriction through activation of NOS in the endothelium. Am J Physiol Regul Integr Comp Physiol (2015) 0.75
Endothelin-1 impairs coronary arteriolar dilation: Role of p38 kinase-mediated superoxide production from NADPH oxidase. J Mol Cell Cardiol (2015) 0.75
Angiotensin II hypertension is attenuated in interleukin-6 knockout mice. Am J Physiol Heart Circ Physiol (2005) 3.22
An orally active epoxide hydrolase inhibitor lowers blood pressure and provides renal protection in salt-sensitive hypertension. Hypertension (2005) 2.76
Soluble epoxide hydrolase inhibition protects the kidney from hypertension-induced damage. J Am Soc Nephrol (2004) 2.59
Regulation of blood pressure and salt homeostasis by endothelin. Physiol Rev (2011) 2.22
Effect of epithelial sodium channel blockade on the myogenic response of rat juxtamedullary afferent arterioles. Hypertension (2009) 1.92
Targets for vascular protection after acute ischemic stroke. Stroke (2004) 1.88
Tumor necrosis factor alpha blockade increases renal Cyp2c23 expression and slows the progression of renal damage in salt-sensitive hypertension. Hypertension (2006) 1.77
Contrasting actions of endothelin ET(A) and ET(B) receptors in cardiovascular disease. Annu Rev Pharmacol Toxicol (2007) 1.74
TNF-alpha inhibition reduces renal injury in DOCA-salt hypertensive rats. Am J Physiol Regul Integr Comp Physiol (2007) 1.73
Endothelin A receptor blockade reduces diabetic renal injury via an anti-inflammatory mechanism. J Am Soc Nephrol (2006) 1.63
Relationship between oxidative stress and inflammatory cytokines in diabetic nephropathy. Cardiovasc Ther (2010) 1.60
An epoxide hydrolase inhibitor, 12-(3-adamantan-1-yl-ureido)dodecanoic acid (AUDA), reduces ischemic cerebral infarct size in stroke-prone spontaneously hypertensive rats. J Cardiovasc Pharmacol (2005) 1.59
Peroxisome proliferator-activated receptor-alpha activation reduces salt-dependent hypertension during chronic endothelin B receptor blockade. Hypertension (2005) 1.56
Antihypertensive therapy increases tetrahydrobiopterin levels and NO/cGMP signaling in small arteries of angiotensin II-infused hypertensive rats. Am J Physiol Heart Circ Physiol (2010) 1.54
Endothelin activation of reactive oxygen species mediates stress-induced pressor response in Dahl salt-sensitive prehypertensive rats. Hypertension (2010) 1.49
Fructose feeding increases insulin resistance but not blood pressure in Sprague-Dawley rats. Hypertension (2005) 1.49
Clopidogrel, independent of the vascular P2Y12 receptor, improves arterial function in small mesenteric arteries from AngII-hypertensive rats. Clin Sci (Lond) (2009) 1.47
Decreased endothelin binding and [Ca2+]i signaling in microvessels of DOCA-salt hypertensive rats. J Hypertens (2002) 1.46
Sex differences in angiotensin-converting enzyme modulation of Ang (1-7) levels in normotensive WKY rats. Am J Hypertens (2013) 1.41
Sex and sex hormones influence the development of albuminuria and renal macrophage infiltration in spontaneously hypertensive rats. Am J Physiol Regul Integr Comp Physiol (2007) 1.35
NADPH oxidase inhibition attenuates oxidative stress but not hypertension produced by chronic ET-1. Hypertension (2004) 1.31
Endothelin-1 increases glomerular permeability and inflammation independent of blood pressure in the rat. Hypertension (2010) 1.30
Renal medullary ETB receptors produce diuresis and natriuresis via NOS1. Am J Physiol Renal Physiol (2008) 1.29
Contribution of endothelin A receptors in endothelin 1-dependent natriuresis in female rats. Hypertension (2008) 1.28
Angiotensin II blockade prevents hyperglycemia-induced activation of JAK and STAT proteins in diabetic rat kidney glomeruli. Am J Physiol Renal Physiol (2003) 1.27
Renal endothelin in chronic angiotensin II hypertension. Am J Physiol Regul Integr Comp Physiol (2002) 1.24
Collecting duct-derived endothelin regulates arterial pressure and Na excretion via nitric oxide. Hypertension (2008) 1.24
Decreased renal cytochrome P450 2C enzymes and impaired vasodilation are associated with angiotensin salt-sensitive hypertension. Hypertension (2002) 1.24
Spironolactone improves structure and increases tone in the cerebral vasculature of male spontaneously hypertensive stroke-prone rats. Microvasc Res (2007) 1.23
Novel use of ultrasound to examine regional blood flow in the mouse kidney. Am J Physiol Renal Physiol (2009) 1.21
Early life stress sensitizes rats to angiotensin II-induced hypertension and vascular inflammation in adult life. Hypertension (2009) 1.21
Hypertension after experimental cerebral ischemia: candesartan provides neurovascular protection. J Hypertens (2006) 1.17
Novel nitric oxide synthase--dependent mechanism of vasorelaxation in small arteries from hypertensive rats. Hypertension (2007) 1.15
Flow regulation of collecting duct endothelin-1 production. Am J Physiol Renal Physiol (2010) 1.15
Low-flow vascular remodeling in the metabolic syndrome X. Am J Physiol Heart Circ Physiol (2003) 1.14
Hypertensive response to acute stress is attenuated in interleukin-6 knockout mice. Hypertension (2004) 1.14
Angiotensin II and endothelin-1 augment the vascular complications of diabetes via JAK2 activation. Am J Physiol Heart Circ Physiol (2007) 1.14
Decreased epoxygenase and increased epoxide hydrolase expression in the mesenteric artery of obese Zucker rats. Am J Physiol Regul Integr Comp Physiol (2004) 1.13
Role of endothelin-1 in clinical hypertension: 20 years on. Hypertension (2008) 1.13
Sexual dimorphism in oxidant status in spontaneously hypertensive rats. Am J Physiol Regul Integr Comp Physiol (2006) 1.10
Chemokine receptor 2b inhibition provides renal protection in angiotensin II - salt hypertension. Hypertension (2007) 1.10
Hypertension: what's sex got to do with it? Physiology (Bethesda) (2013) 1.09
Physiology of endothelin and the kidney. Compr Physiol (2011) 1.08
Functional role of ETB receptors in the renal medulla. Hypertension (2003) 1.08
Renal collecting duct NOS1 maintains fluid-electrolyte homeostasis and blood pressure. Hypertension (2013) 1.07
Exaggerated cardiovascular stress responses and impaired beta-adrenergic-mediated pressor recovery in obese Zucker rats. Hypertension (2006) 1.07
Gender differences in ET and NOS systems in ETB receptor-deficient rats: effect of a high salt diet. Hypertension (2002) 1.06
Dynamin activates NO production in rat renal inner medullary collecting ducts via protein-protein interaction with NOS1. Am J Physiol Renal Physiol (2011) 1.06
Sex differences in renal medullary endothelin receptor function in angiotensin II hypertensive rats. Hypertension (2011) 1.06
Salt-sensitive hypertension after exposure to angiotensin is associated with inability to upregulate renal epoxygenases. Hypertension (2003) 1.05
Arterial pressure response to the antioxidant tempol and ETB receptor blockade in rats on a high-salt diet. Hypertension (2004) 1.03
Protective role of extracellular superoxide dismutase in renal ischemia/reperfusion injury. Kidney Int (2010) 1.02
Distinct actions of endothelin A-selective versus combined endothelin A/B receptor antagonists in early diabetic kidney disease. J Pharmacol Exp Ther (2011) 1.01
Altered nitric oxide synthase 3 distribution in mesenteric arteries of hypertensive rats. Hypertension (2002) 1.01
Racial differences in microalbumin excretion in healthy adolescents. Hypertension (2008) 1.01
Tactics for vascular protection after acute ischemic stroke. Pharmacotherapy (2005) 1.01
Reduced NOS3 phosphorylation mediates reduced NO/cGMP signaling in mesenteric arteries of deoxycorticosterone acetate-salt hypertensive rats. Hypertension (2004) 0.99
Endothelin antagonists for diabetic and non-diabetic chronic kidney disease. Br J Clin Pharmacol (2013) 0.99
Attenuated vasoconstrictor responses to endothelin in afferent arterioles during a high-salt diet. Am J Physiol Renal Physiol (2007) 0.98
Early life stress downregulates endothelin receptor expression and enhances acute stress-mediated blood pressure responses in adult rats. Am J Physiol Regul Integr Comp Physiol (2010) 0.97
Extracellular signal-regulated kinase 1/2 activation, via downregulation of mitogen-activated protein kinase phosphatase 1, mediates sex differences in desoxycorticosterone acetate-salt hypertension vascular reactivity. Hypertension (2009) 0.97
Endothelin antagonism prevents early EGFR transactivation but not increased matrix metalloproteinase activity in diabetes. Am J Physiol Regul Integr Comp Physiol (2005) 0.97
ETA and ETB receptors differentially modulate afferent and efferent arteriolar responses to endothelin. Br J Pharmacol (2005) 0.97
Endothelin, kidney disease, and hypertension. Hypertension (2013) 0.97
Impaired Ca2+ signaling attenuates P2X receptor-mediated vasoconstriction of afferent arterioles in angiotensin II hypertension. Hypertension (2005) 0.96
O-GlcNAcylation contributes to augmented vascular reactivity induced by endothelin 1. Hypertension (2009) 0.96
Matrix metalloproteinase 2 and 9 dysfunction underlie vascular stiffness in circadian clock mutant mice. Arterioscler Thromb Vasc Biol (2010) 0.96
Plasma endothelin-1 release during acute stress: role of ethnicity and sex. Psychosom Med (2002) 0.96
PP2B-dependent NO production in the medullary thick ascending limb during diabetes. Am J Physiol Renal Physiol (2009) 0.95
Female spontaneously hypertensive rats have greater renal anti-inflammatory T lymphocyte infiltration than males. Am J Physiol Regul Integr Comp Physiol (2012) 0.95