PubRank

Jeremy J Lambert

Author PubWeight™ 56.92‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Neurosteroids: endogenous regulators of the GABA(A) receptor. Nat Rev Neurosci 2005 4.07
2 Tonic inhibition in mouse hippocampal CA1 pyramidal neurons is mediated by alpha5 subunit-containing gamma-aminobutyric acid type A receptors. Proc Natl Acad Sci U S A 2004 3.21
3 A cytoplasmic region determines single-channel conductance in 5-HT3 receptors. Nature 2003 2.47
4 How can drug discovery for psychiatric disorders be improved? Nat Rev Drug Discov 2007 2.29
5 Extrasynaptic GABAA receptors of thalamocortical neurons: a molecular target for hypnotics. J Neurosci 2005 2.03
6 Sedation and anesthesia mediated by distinct GABA(A) receptor isoforms. J Neurosci 2003 1.97
7 The influence of subunit composition on the interaction of neurosteroids with GABA(A) receptors. Neuropharmacology 2002 1.85
8 The delta subunit of gamma-aminobutyric acid type A receptors does not confer sensitivity to low concentrations of ethanol. J Pharmacol Exp Ther 2005 1.82
9 Neurosteroid modulation of synaptic and extrasynaptic GABA(A) receptors. Pharmacol Ther 2007 1.56
10 Small molecule antagonists of the sigma-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo. Cancer Res 2004 1.49
11 The expression of GABAA beta subunit isoforms in synaptic and extrasynaptic receptor populations of mouse dentate gyrus granule cells. J Physiol 2007 1.42
12 Common determinants of single channel conductance within the large cytoplasmic loop of 5-hydroxytryptamine type 3 and alpha4beta2 nicotinic acetylcholine receptors. J Biol Chem 2006 1.39
13 Cocaine effects on mouse incentive-learning and human addiction are linked to alpha2 subunit-containing GABAA receptors. Proc Natl Acad Sci U S A 2010 1.27
14 Distinct mechanisms regulate GABAA receptor and gephyrin clustering at perisomatic and axo-axonic synapses on CA1 pyramidal cells. J Physiol 2011 1.25
15 The in vitro and in vivo enantioselectivity of etomidate implicates the GABAA receptor in general anaesthesia. Neuropharmacology 2003 1.22
16 Novel structural determinants of single channel conductance and ion selectivity in 5-hydroxytryptamine type 3 and nicotinic acetylcholine receptors. J Physiol 2009 1.19
17 Inhibition of thalamic excitability by 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine-3-ol: a selective role for delta-GABA(A) receptors. Eur J Neurosci 2009 1.18
18 Neurosteroid modulation of GABAA receptors: molecular determinants and significance in health and disease. Neurochem Int 2007 1.16
19 Molecular determinants of single-channel conductance and ion selectivity in the Cys-loop family: insights from the 5-HT3 receptor. Trends Pharmacol Sci 2005 1.11
20 Developmental maturation of synaptic and extrasynaptic GABAA receptors in mouse thalamic ventrobasal neurones. J Physiol 2007 1.10
21 Characterization of the effects of charged residues in the intracellular loop on ion permeation in alpha1 glycine receptor channels. J Biol Chem 2008 1.08
22 Structural determinants of Ca2+ permeability and conduction in the human 5-hydroxytryptamine type 3A receptor. J Biol Chem 2008 1.07
23 Assembly and cell surface expression of homomeric and heteromeric 5-HT3 receptors: the role of oligomerization and chaperone proteins. Mol Cell Neurosci 2002 1.07
24 Dynamic modification of a mutant cytoplasmic cysteine residue modulates the conductance of the human 5-HT3A receptor. J Biol Chem 2007 1.05
25 Neurosteroids and GABA(A) Receptor Interactions: A Focus on Stress. Front Neurosci 2011 1.04
26 GABA-independent GABAA receptor openings maintain tonic currents. J Neurosci 2013 1.00
27 Extrasynaptic GABA(A) receptors couple presynaptic activity to postsynaptic inhibition in the somatosensory thalamus. J Neurosci 2013 1.00
28 Antidepressants and antipsychotic drugs colocalize with 5-HT3 receptors in raft-like domains. J Neurosci 2005 1.00
29 Phosphorylation influences neurosteroid modulation of synaptic GABAA receptors in rat CA1 and dentate gyrus neurones. Neuropharmacology 2003 0.99
30 Dysfunctional astrocytic and synaptic regulation of hypothalamic glutamatergic transmission in a mouse model of early-life adversity: relevance to neurosteroids and programming of the stress response. J Neurosci 2013 0.96
31 GABA receptor-mediated effects in the peripheral nervous system: A cross-interaction with neuroactive steroids. J Mol Neurosci 2006 0.95
32 Mutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibition. Nat Commun 2013 0.94
33 Rings of charge within the extracellular vestibule influence ion permeation of the 5-HT3A receptor. J Biol Chem 2011 0.91
34 Tonic inhibition of accumbal spiny neurons by extrasynaptic α4βδ GABAA receptors modulates the actions of psychostimulants. J Neurosci 2014 0.91
35 The minimum M3-M4 loop length of neurotransmitter-activated pentameric receptors is critical for the structural integrity of cytoplasmic portals. J Biol Chem 2013 0.88
36 A transmembrane residue influences the interaction of propofol with the strychnine-sensitive glycine alpha1 and alpha1beta receptor. Anesth Analg 2008 0.85
37 GABAB receptors in Schwann cells influence proliferation and myelin protein expression. Eur J Neurosci 2004 0.84
38 Mutagenic analysis of the intracellular portals of the human 5-HT3A receptor. J Biol Chem 2013 0.83
39 Bi-directional modulation of fast inhibitory synaptic transmission by leptin. J Neurochem 2009 0.81
40 Developmentally regulated neurosteroid synthesis enhances GABAergic neurotransmission in mouse thalamocortical neurones. J Physiol 2014 0.80
41 Synthesis, conformation and biological evaluation of the enantiomers of 3-fluoro-gamma-aminobutyric acid ((R)- and (S)-3F-GABA): an analogue of the neurotransmitter GABA. Chembiochem 2007 0.79
42 Localisation and stress-induced plasticity of GABAA receptor subunits within the cellular networks of the mouse dorsal raphe nucleus. Brain Struct Funct 2014 0.79
43 The general anaesthetic etomidate inhibits the excitability of mouse thalamocortical relay neurons by modulating multiple modes of GABAA receptor-mediated inhibition. Eur J Neurosci 2014 0.76
44 5-Chloroindole: a potent allosteric modulator of the 5-HT₃ receptor. Br J Pharmacol 2013 0.76