Published in Mol Cell on May 25, 2007
Newer antibacterial drugs for a new century. Expert Opin Investig Drugs (2010) 1.16
Telithromycin and quinupristin-dalfopristin induce delayed death in Plasmodium falciparum. Antimicrob Agents Chemother (2007) 0.89
Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process. EMBO J (2002) 3.57
Small RNA binding to 5' mRNA coding region inhibits translational initiation. Mol Cell (2008) 2.88
The highly conserved LepA is a ribosomal elongation factor that back-translocates the ribosome. Cell (2006) 2.19
An unexpected type of ribosomes induced by kasugamycin: a look into ancestral times of protein synthesis? Mol Cell (2009) 2.03
Dissection of the mechanism for the stringent factor RelA. Mol Cell (2002) 1.98
The weird and wonderful world of bacterial ribosome regulation. Crit Rev Biochem Mol Biol (2007) 1.97
Dissecting the ribosomal inhibition mechanisms of edeine and pactamycin: the universally conserved residues G693 and C795 regulate P-site RNA binding. Mol Cell (2004) 1.83
EF-G2mt is an exclusive recycling factor in mammalian mitochondrial protein synthesis. Mol Cell (2009) 1.82
Ribosomal protection proteins and their mechanism of tetracycline resistance. Antimicrob Agents Chemother (2003) 1.70
Ribosomal proteins in the spotlight. Crit Rev Biochem Mol Biol (2005) 1.69
Maintaining the ribosomal reading frame: the influence of the E site during translational regulation of release factor 2. Cell (2004) 1.68
Fast biosynthesis of GFP molecules: a single-molecule fluorescence study. Angew Chem Int Ed Engl (2009) 1.53
A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation. Nat Struct Mol Biol (2008) 1.50
The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation. Nat Struct Mol Biol (2006) 1.47
EF-G-dependent GTPase on the ribosome. conformational change and fusidic acid inhibition. Biochemistry (2006) 1.46
Heteronuclear NMR investigations of dynamic regions of intact Escherichia coli ribosomes. Proc Natl Acad Sci U S A (2004) 1.31
Structure and dynamics of the mammalian ribosomal pretranslocation complex. Mol Cell (2011) 1.28
Species-specific antibiotic-ribosome interactions: implications for drug development. Biol Chem (2005) 1.27
Elongation factor 4 (EF4/LepA) accelerates protein synthesis at increased Mg2+ concentrations. Proc Natl Acad Sci U S A (2011) 1.24
New features of the ribosome and ribosomal inhibitors: non-enzymatic recycling, misreading and back-translocation. J Mol Biol (2008) 1.23
Three-dimensional structures of translating ribosomes by Cryo-EM. Mol Cell (2004) 1.21
Heptameric (L12)6/L10 rather than canonical pentameric complexes are found by tandem MS of intact ribosomes from thermophilic bacteria. Proc Natl Acad Sci U S A (2005) 1.21
Mechanism of Tet(O)-mediated tetracycline resistance. EMBO J (2003) 1.19
Protein synthesis at atomic resolution: mechanistics of translation in the light of highly resolved structures for the ribosome. Curr Protein Pept Sci (2002) 1.11
The ribosome through the looking glass. Angew Chem Int Ed Engl (2003) 1.10
The complex of tmRNA-SmpB and EF-G on translocating ribosomes. Nature (2012) 1.09
Shine-Dalgarno interaction prevents incorporation of noncognate amino acids at the codon following the AUG. Proc Natl Acad Sci U S A (2008) 1.08
Retracted A dedicated translation factor controls the synthesis of the global regulator Fis. EMBO J (2004) 1.07
RsfA (YbeB) proteins are conserved ribosomal silencing factors. PLoS Genet (2012) 1.06
Dissociation of intact Escherichia coli ribosomes in a mass spectrometer. Evidence for conformational change in a ribosome elongation factor G complex. J Biol Chem (2002) 1.01
Stepping transfer messenger RNA through the ribosome. J Biol Chem (2005) 1.01
Codon-anticodon interaction at the P site is a prerequisite for tRNA interaction with the small ribosomal subunit. J Biol Chem (2002) 1.01
Deacylated tRNA is released from the E site upon A site occupation but before GTP is hydrolyzed by EF-Tu. Nucleic Acids Res (2005) 1.00
NOA1 is an essential GTPase required for mitochondrial protein synthesis. Mol Biol Cell (2010) 1.00
Structural basis for the binding of IRES RNAs to the head of the ribosomal 40S subunit. Nucleic Acids Res (2011) 0.99
DnaK-facilitated ribosome assembly in Escherichia coli revisited. RNA (2003) 0.98
Features of 80S mammalian ribosome and its subunits. Nucleic Acids Res (2008) 0.96
Cell-free protein expression and functional assay in nanowell chip format. Anal Chem (2004) 0.96
RNA-structural mimicry in Escherichia coli ribosomal protein L4-dependent regulation of the S10 operon. J Biol Chem (2003) 0.95
The tetracycline resistance protein Tet(o) perturbs the conformation of the ribosomal decoding centre. Mol Microbiol (2002) 0.92
Mapping of the second tetracycline binding site on the ribosomal small subunit of E.coli. Nucleic Acids Res (2004) 0.90
Localization of the trigger factor binding site on the ribosomal 50S subunit. J Mol Biol (2003) 0.90
How does tmRNA move through the ribosome? FEBS Lett (2002) 0.89
Formation of 70S ribosomes: large activation energy is required for the adaptation of exclusively the small ribosomal subunit. Biophys Chem (2002) 0.89
Troubleshooting coupled in vitro transcription-translation system derived from Escherichia coli cells: synthesis of high-yield fully active proteins. Nucleic Acids Res (2006) 0.89
Question 7: optimized energy consumption for protein synthesis. Orig Life Evol Biosph (2007) 0.87
Erythromycin, roxithromycin, and clarithromycin: use of slow-binding kinetics to compare their in vitro interaction with a bacterial ribosomal complex active in peptide bond formation. Mol Pharmacol (2003) 0.87
A conserved proline switch on the ribosome facilitates the recruitment and binding of trGTPases. Nat Struct Mol Biol (2012) 0.83
The how and Y of cold shock. Nat Struct Mol Biol (2004) 0.82
RelBE or not to be. Nat Struct Mol Biol (2005) 0.81
Lys53 of ribosomal protein L36AL and the CCA end of a tRNA at the P/E hybrid site are in close proximity on the human ribosome. Chembiochem (2012) 0.80
Problems with the Analyses of the Ribosomal Allosteric Three-site Model. J Biol Chem (2012) 0.79
The thorny way to the mechanism of ribosomal peptide-bond formation. Chembiochem (2012) 0.79
Three mechanisms in Escherichia coli rescue ribosomes stalled on non-stop mRNAs: one of them requires release factor 2. Mol Microbiol (2012) 0.77
Common chaperone activity in the G-domain of trGTPase protects L11-L12 interaction on the ribosome. Nucleic Acids Res (2012) 0.77
Translocation at work. Nat Struct Mol Biol (2013) 0.76
Identical binding sites--nonidentical functions in Eukarya and Archaea: the complex of aeIF6 with the large ribosomal subunit. J Mol Biol (2012) 0.76
Ribosomal peptide-bond formation. Chem Biol (2008) 0.76
In vitro selection of random RNA fragments to identify protein-binding sites within large RNAs. Methods Mol Biol (2008) 0.75
Ribosomes deprived of select proteins show similar structural alterations induced by thermal treatment of native particles. Cell Biochem Biophys (2005) 0.75
Biophysical study of a molecular intermediate preceding collapse of tight couple and Kaltschmidt-Wittmann ribosomes. FEBS Lett (2002) 0.75
Characterization of RNA-protein interactions by phosphorothioate footprinting and its applications to the ribosome. Methods Mol Biol (2008) 0.75