Published in Bone on April 20, 2007
Osteoarthritis associated with estrogen deficiency. Arthritis Res Ther (2009) 1.28
Manipulation of Ovarian Function Significantly Influenced Trabecular and Cortical Bone Volume, Architecture and Density in Mice at Death. PLoS One (2015) 0.81
Effects of long-term estrogen replacement therapy on bone turnover in periarticular tibial osteophytes in surgically postmenopausal cynomolgus monkeys. Bone (2007) 0.79
Ligustrazine Inhibits Cartilage Endplate Hypertrophy via Suppression of TGF-β1. Evid Based Complement Alternat Med (2016) 0.75
Osteoarthritis: new insights. Part 1: the disease and its risk factors. Ann Intern Med (2000) 11.12
Atlas of individual radiographic features in osteoarthritis. Osteoarthritis Cartilage (1995) 7.18
The role of knee alignment in disease progression and functional decline in knee osteoarthritis. JAMA (2001) 7.15
Obesity and knee osteoarthritis. The Framingham Study. Ann Intern Med (1988) 6.36
Weight loss reduces the risk for symptomatic knee osteoarthritis in women. The Framingham Study. Ann Intern Med (1992) 5.05
Risk factors for incident radiographic knee osteoarthritis in the elderly: the Framingham Study. Arthritis Rheum (1997) 4.08
The incidence and natural history of knee osteoarthritis in the elderly. The Framingham Osteoarthritis Study. Arthritis Rheum (1995) 3.93
A 12 year follow up study in the general population on prognostic factors of cartilage loss in osteoarthritis of the knee. Ann Rheum Dis (1992) 2.52
The role of subchondral bone remodeling in osteoarthritis: reduction of cartilage degeneration and prevention of osteophyte formation by alendronate in the rat anterior cruciate ligament transection model. Arthritis Rheum (2004) 2.22
Inhibition of postmenopausal atherosclerosis progression: a comparison of the effects of conjugated equine estrogens and soy phytoestrogens. J Clin Endocrinol Metab (2001) 2.16
Longitudinal radiologic evaluation of osteoarthritis of the knee. J Rheumatol (1992) 1.93
The relationship between osteophytes in the knee joint, osteoarthritis and aging. Acta Orthop Scand (1973) 1.66
Overweight, gender and knee osteoarthritis. Int J Obes Relat Metab Disord (1996) 1.63
Osteoarthritis-like changes in the murine knee joint resulting from intra-articular transforming growth factor-beta injections. Osteoarthritis Cartilage (2000) 1.59
Development of periarticular osteophytes in experimentally induced osteoarthritis in the dog. A study using microradiographic, microangiographic, and fluorescent bone-labelling techniques. Ann Rheum Dis (1975) 1.49
Synovial lining macrophages mediate osteophyte formation during experimental osteoarthritis. Osteoarthritis Cartilage (2004) 1.47
Development of a logically devised line drawing atlas for grading of knee osteoarthritis. Ann Rheum Dis (2000) 1.46
Inhibition of endogenous TGF-beta during experimental osteoarthritis prevents osteophyte formation and impairs cartilage repair. J Immunol (2002) 1.46
Different cytokine profiles in the synovial fluid of patients with osteoarthritis, rheumatoid arthritis and seronegative spondylarthropathies. Clin Exp Rheumatol (1996) 1.44
Osteoarthritis in cynomolgus macaques. III: Effects of age, gender, and subchondral bone thickness on the severity of disease. J Bone Miner Res (1996) 1.39
Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation. Osteoarthritis Cartilage (2001) 1.36
Crucial role of synovial lining macrophages in the promotion of transforming growth factor beta-mediated osteophyte formation. Arthritis Rheum (2004) 1.32
Osteophytes and progression of knee osteoarthritis. Rheumatology (Oxford) (2004) 1.31
Periarticular osteophytes. Initiation and formation in the knee of the dog. Clin Orthop Relat Res (1969) 1.17
Synovial fluid cytokine concentrations as possible prognostic indicators in the ACL-deficient knee. Knee Surg Sports Traumatol Arthrosc (1994) 1.15
Effects of long-term estrogen replacement therapy on osteoarthritis severity in cynomolgus monkeys. Arthritis Rheum (2002) 1.10
Treatment with calcitonin suppresses the responses of bone, cartilage, and synovium in the early stages of canine experimental osteoarthritis and significantly reduces the severity of the cartilage lesions. Arthritis Rheum (1999) 0.98
Immobilization of the knee prevents osteoarthritis after anterior cruciate ligament transection. Arthritis Rheum (1982) 0.96
Effects of estrogen replacement therapy on bone turnover in subchondral bone and epiphyseal metaphyseal cancellous bone of ovariectomized cynomolgus monkeys. J Bone Miner Res (2004) 0.95
Characterisation of size and direction of osteophyte in knee osteoarthritis: a radiographic study. Ann Rheum Dis (2002) 0.90
Early changes in the knee joint due to instability induced by cutting of the anterior cruciate ligament. An experimental study in young dogs. Acta Radiol Suppl (1972) 0.84
Bone remodeling in osteoarthritis: subchondral and osteophytic responses. Osteoarthritis Cartilage (1999) 0.83
The relation between cartilage damage and osteophyte size in a murine model for osteoarthritis in the knee. Rheumatol Int (1996) 0.83
PTHrP, PTHr, and FGFR3 are involved in the process of endochondral ossification in human osteophytes. Histochem Cell Biol (2003) 0.82
Determination of age in monkeys (Macaca irus) on the basis of dental development. Lab Anim (1970) 0.81
Osteophyte formation in the canine stifle joint following treatment for rupture of the cranial cruciate ligament. J Small Anim Pract (1979) 0.79
Detection of synovial macrophages in the joint capsule of dogs with naturally occurring rupture of the cranial cruciate ligament. Am J Vet Res (2005) 0.78
Nitric oxide levels and nitric oxide synthase expression in uterine samples from mares susceptible and resistant to persistent breeding-induced endometritis. Am J Reprod Immunol (2005) 1.98
Microarray analysis reveals age-related differences in gene expression during the development of osteoarthritis in mice. Arthritis Rheum (2012) 1.91
The DIRE score: predicting outcomes of opioid prescribing for chronic pain. J Pain (2006) 1.89
Wear analysis of the Bryan Cervical Disc prosthesis. Spine (Phila Pa 1976) (2003) 1.82
Sequential therapy with sorafenib and sunitinib in renal cell carcinoma. Cancer (2009) 1.72
Increase in production of matrix metalloproteinase 13 by human articular chondrocytes due to stimulation with S100A4: Role of the receptor for advanced glycation end products. Arthritis Rheum (2006) 1.65
Articular chondrocytes express the receptor for advanced glycation end products: Potential role in osteoarthritis. Arthritis Rheum (2005) 1.65
Cartilage oligomeric matrix protein associates with granulin-epithelin precursor (GEP) and potentiates GEP-stimulated chondrocyte proliferation. J Biol Chem (2007) 1.55
Detection of nitrotyrosine in aging and osteoarthritic cartilage: Correlation of oxidative damage with the presence of interleukin-1beta and with chondrocyte resistance to insulin-like growth factor 1. Arthritis Rheum (2002) 1.49
The mammalian twisted gastrulation gene functions in foregut and craniofacial development. Dev Biol (2004) 1.45
Adult-onset growth hormone and insulin-like growth factor I deficiency reduces neoplastic disease, modifies age-related pathology, and increases life span. Endocrinology (2005) 1.45
Chronic and recurrent otitis media: a genome scan for susceptibility loci. Am J Hum Genet (2004) 1.44
Allogeneic natural killer cells for refractory lymphoma. Cancer Immunol Immunother (2010) 1.42
The Bryan Cervical Disc: wear properties and early clinical results. Spine J (2004) 1.41
Reduced small artery but not large artery elasticity is an independent risk marker for cardiovascular events. Am J Hypertens (2003) 1.27
Systemic correction of storage disease in MPS I NOD/SCID mice using the sleeping beauty transposon system. Mol Ther (2009) 1.24
Effect of oral snus and medicinal nicotine in smokers on toxicant exposure and withdrawal symptoms: a feasibility study. Cancer Epidemiol Biomarkers Prev (2010) 1.15
Focal changes in blood supply during normal epiphyseal growth are central in the pathogenesis of osteochondrosis in pigs. Bone (2004) 1.15
Matrix-matrix interaction of cartilage oligomeric matrix protein and fibronectin. Matrix Biol (2002) 1.14
Effects of long-term estrogen replacement therapy on osteoarthritis severity in cynomolgus monkeys. Arthritis Rheum (2002) 1.10
Racial diversity with high nucleated cell counts and CD34 counts achieved in a national network of cord blood banks. Biol Blood Marrow Transplant (2004) 1.10
Disease progression and phasic changes in gene expression in a mouse model of osteoarthritis. PLoS One (2013) 1.02
A therapeutic trial of decitabine and vorinostat in combination with chemotherapy for relapsed/refractory acute lymphoblastic leukemia. Am J Hematol (2014) 1.01
Alterations in mineral composition observed in osteoarthritic joints of cynomolgus monkeys. Bone (2004) 1.01
Cotinine and trans 3'-hydroxycotinine in dried blood spots as biomarkers of tobacco exposure and nicotine metabolism. J Expo Sci Environ Epidemiol (2013) 1.01
Quantitation of pyridyloxobutyl DNA adducts in nasal and oral mucosa of rats treated chronically with enantiomers of N'-nitrosonornicotine. Chem Res Toxicol (2009) 1.00
Increased expression of the Akt/PKB inhibitor TRB3 in osteoarthritic chondrocytes inhibits insulin-like growth factor 1-mediated cell survival and proteoglycan synthesis. Arthritis Rheum (2009) 0.99
Analysis of pyridyloxobutyl and pyridylhydroxybutyl DNA adducts in extrahepatic tissues of F344 rats treated chronically with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol. Chem Res Toxicol (2009) 0.99
Cochlear changes in chronic otitis media. Laryngoscope (2004) 0.98
Early lesions of osteochondrosis in the distal tibia of foals. J Orthop Res (2007) 0.98
Experimental ischemia of porcine growth cartilage produces lesions of osteochondrosis. J Orthop Res (2004) 0.97
Tobacco smoke exposure in nonsmoking hospitality workers before and after a state smoking ban. Cancer Epidemiol Biomarkers Prev (2010) 0.96
Comparative levels of O6-methylguanine, pyridyloxobutyl-, and pyridylhydroxybutyl-DNA adducts in lung and liver of rats treated chronically with the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Drug Metab Dispos (2009) 0.96
Discectomy strategies for lumbar disc herniation: results of the LAPDOG trial. J Clin Neurosci (2002) 0.96
Effects of estrogen replacement therapy on bone turnover in subchondral bone and epiphyseal metaphyseal cancellous bone of ovariectomized cynomolgus monkeys. J Bone Miner Res (2004) 0.95
The interferon-inducible p204 protein acts as a transcriptional coactivator of Cbfa1 and enhances osteoblast differentiation. J Biol Chem (2004) 0.94
An in vivo injury model of posterolateral knee instability. Am J Sports Med (2006) 0.91
Histologic and immunohistochemical characteristics of failed articular cartilage resurfacing procedures for osteochondritis of the knee: a case series. Am J Sports Med (2007) 0.91
In situ chemistry of osteoporosis revealed by synchrotron infrared microspectroscopy. Bone (2003) 0.90
Inhibition of angiogenesis and suppression of colorectal cancer metastatic to the liver using the Sleeping Beauty Transposon System. Mol Cancer (2011) 0.89
Outcomes of 122 diverse adult and pediatric cord blood transplant recipients from a large cord blood bank. Transfusion (2006) 0.87
The effects of estrogen on material and mechanical properties of the intra- and extra-articular knee structures. Am J Sports Med (2006) 0.87
Effects of chronic growth hormone and insulin-like growth factor 1 deficiency on osteoarthritis severity in rat knee joints. Arthritis Rheum (2006) 0.86
Serum albumin and body weight as biomarkers for the antemortem identification of bone and gastrointestinal disease in the common marmoset. PLoS One (2013) 0.86
Histological confirmation and biological significance of cartilage canals demonstrated using high field MRI in swine at predilection sites of osteochondrosis. J Orthop Res (2013) 0.86
Inflammation, apoptosis, and necrosis induced by neoadjuvant fas ligand gene therapy improves survival of dogs with spontaneous bone cancer. Mol Ther (2012) 0.85
The influence of repair pathways on the cytotoxicity and mutagenicity induced by the pyridyloxobutylation pathway of tobacco-specific nitrosamines. Chem Res Toxicol (2009) 0.85
Regional gene therapy for full-thickness articular cartilage lesions using naked DNA with a collagen matrix. J Orthop Res (2006) 0.85
MRI rotating frame relaxation measurements for articular cartilage assessment. Magn Reson Imaging (2013) 0.85
Susceptibility weighted imaging of cartilage canals in porcine epiphyseal growth cartilage ex vivo and in vivo. Magn Reson Med (2013) 0.85
The oncogene LRF is a survival factor in chondrosarcoma and contributes to tumor malignancy and drug resistance. Carcinogenesis (2012) 0.84
Brachial plexus birth palsy-associated shoulder deformity: a rat model study. J Hand Surg Am (2008) 0.83
GEP constitutes a negative feedback loop with MyoD and acts as a novel mediator in controlling skeletal muscle differentiation. Cell Mol Life Sci (2011) 0.83
Chronic otitis media with effusion sequelae in children treated with tubes. Arch Otolaryngol Head Neck Surg (2003) 0.80
The tyrosine phosphatase, OST-PTP, is expressed in mesenchymal progenitor cells early during skeletogenesis in the mouse. J Cell Biochem (2004) 0.79
A randomized controlled trial comparing health and quality of life of lung transplant recipients following nurse and computer-based triage utilizing home spirometry monitoring. Telemed J E Health (2013) 0.79
Effects of long-term estrogen replacement therapy on bone turnover in periarticular tibial osteophytes in surgically postmenopausal cynomolgus monkeys. Bone (2007) 0.79
The effect of young age on outcomes in head and neck cancer. Laryngoscope (2013) 0.78
Targeted overexpression of an activated N-ras gene results in B-cell and plasma cell lymphoproliferation and cooperates with c-myc to induce fatal B-cell neoplasia. Exp Hematol (2011) 0.78
Discectomy strategies for lumbar disc herniation: study design and implications for clinical research. J Clin Neurosci (2002) 0.78
Exposure to a tobacco-specific lung carcinogen in adolescent versus adult smokers. Cancer Epidemiol Biomarkers Prev (2008) 0.78
Expression of bone morphogenetic proteins by Dupuytren's fibroblasts. J Hand Surg Am (2004) 0.78
Assessment of a goat model of posterolateral knee instability. J Orthop Res (2008) 0.78
Influence of bone morphogenetic protein-2 on the extracellular matrix, material properties, and gene expression of long-term articular chondrocyte cultures: loss of chondrocyte stability. Tissue Eng Part A (2009) 0.78
A comparative analysis of 7.0-Tesla magnetic resonance imaging and histology measurements of knee articular cartilage in a canine posterolateral knee injury model: a preliminary analysis. Am J Sports Med (2009) 0.78
The effect of treating institution on outcomes in head and neck cancer. Otolaryngol Head Neck Surg (2012) 0.77
Development of a remote monitoring satisfaction survey and its use in a clinical trial with lung transplant recipients. J Telemed Telecare (2011) 0.77
Some statistical methods for investigating the date of birth as a disease indicator. Stat Med (2003) 0.77
Development of a fracture osteomyelitis model in the rat femur. J Orthop Res (2011) 0.77
The effect of dietary supplementation with limonene or myo-inositol on the induction of neoplasia and matrix metalloproteinase and plasminogen activator activities in accessory sex organs of male Lobund-Wistar rats. Exp Mol Pathol (2008) 0.76
Left- versus right-hand tracking performance by right-handed boys and girls: examination of performance asymmetry. Percept Mot Skills (2003) 0.76
Newsletters and adherence to a weekly home spirometry program after lung transplant. Prog Transplant (2010) 0.76
Pathology in practice. Productive osteoblastic osteosarcoma of the left humerus with unilateral eye, cervical muscle, pulmonary, renal, jejunal mesentery, and liver metastases. J Am Vet Med Assoc (2014) 0.75
The influence of bleeding on trigger changes for platelet transfusion in patients with chemotherapy-induced thrombocytopenia. Transfusion (2012) 0.75
Effect of intra-articular pressurization associated with arthroscopy on the immature physis: investigation in an animal model. J Pediatr Orthop (2009) 0.75