Published in Dev Comp Immunol on May 22, 2007
Cell-mediated immune responses in tuberculosis. Annu Rev Immunol (2009) 5.90
mpeg1 promoter transgenes direct macrophage-lineage expression in zebrafish. Blood (2010) 2.82
A replication clock for Mycobacterium tuberculosis. Nat Med (2009) 2.49
Definitive hematopoiesis initiates through a committed erythromyeloid progenitor in the zebrafish embryo. Development (2007) 2.33
Zebrafish in hematology: sushi or science? Blood (2008) 1.69
Eosinophils in the zebrafish: prospective isolation, characterization, and eosinophilia induction by helminth determinants. Blood (2010) 1.69
Host-pathogen interactions made transparent with the zebrafish model. Curr Drug Targets (2011) 1.60
Lung neutrophils facilitate activation of naive antigen-specific CD4+ T cells during Mycobacterium tuberculosis infection. J Immunol (2011) 1.56
A high-throughput screen for tuberculosis progression. PLoS One (2011) 1.48
Direct In Vivo Manipulation and Imaging of Calcium Transients in Neutrophils Identify a Critical Role for Leading-Edge Calcium Flux. Cell Rep (2015) 1.43
Characterization of zebrafish larval inflammatory macrophages. Dev Comp Immunol (2009) 1.37
Live imaging of disseminated candidiasis in zebrafish reveals role of phagocyte oxidase in limiting filamentous growth. Eukaryot Cell (2011) 1.34
Live imaging reveals differing roles of macrophages and neutrophils during zebrafish tail fin regeneration. J Biol Chem (2012) 1.30
The epithelial cell adhesion molecule EpCAM is required for epithelial morphogenesis and integrity during zebrafish epiboly and skin development. PLoS Genet (2009) 1.29
Towards a new combination therapy for tuberculosis with next generation benzothiazinones. EMBO Mol Med (2014) 1.27
Burkholderia cenocepacia creates an intramacrophage replication niche in zebrafish embryos, followed by bacterial dissemination and establishment of systemic infection. Infect Immun (2010) 1.25
Insights into early mycobacterial pathogenesis from the zebrafish. Curr Opin Microbiol (2008) 1.23
Automated processing of zebrafish imaging data: a survey. Zebrafish (2013) 1.14
Comparison of static immersion and intravenous injection systems for exposure of zebrafish embryos to the natural pathogen Edwardsiella tarda. BMC Immunol (2011) 1.12
Fate mapping embryonic blood in zebrafish: multi- and unipotential lineages are segregated at gastrulation. Dev Cell (2009) 1.09
Pathogen recognition and activation of the innate immune response in zebrafish. Adv Hematol (2012) 1.07
Innate immune response to Streptococcus iniae infection in zebrafish larvae. Infect Immun (2012) 1.05
Macrophage-pathogen interactions in infectious diseases: new therapeutic insights from the zebrafish host model. Dis Model Mech (2014) 1.02
The ENTH domain protein Clint1 is required for epidermal homeostasis in zebrafish. Development (2009) 1.00
Mediator subunit 12 is required for neutrophil development in zebrafish. PLoS One (2011) 0.96
Unexpected link between lipooligosaccharide biosynthesis and surface protein release in Mycobacterium marinum. J Biol Chem (2012) 0.96
Muscle degeneration and leukocyte infiltration caused by mutation of zebrafish Fad24. Dev Dyn (2009) 0.96
Runx1 regulates embryonic myeloid fate choice in zebrafish through a negative feedback loop inhibiting Pu.1 expression. Blood (2012) 0.90
Neutrophil reverse migration becomes transparent with zebrafish. Adv Hematol (2012) 0.87
Modeling innate immune response to early Mycobacterium infection. Comput Math Methods Med (2012) 0.87
Macrophage Epithelial Reprogramming Underlies Mycobacterial Granuloma Formation and Promotes Infection. Immunity (2016) 0.86
Fit for consumption: zebrafish as a model for tuberculosis. Dis Model Mech (2014) 0.86
Functions of flt3 in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia. Blood (2014) 0.85
Distinct regulation of the anterior and posterior myeloperoxidase expression by Etv2 and Gata1 during primitive Granulopoiesis in zebrafish. Dev Biol (2014) 0.85
DNA methyltransferase 1 functions through C/ebpa to maintain hematopoietic stem and progenitor cells in zebrafish. J Hematol Oncol (2015) 0.85
Neutrophils in host defense: new insights from zebrafish. J Leukoc Biol (2015) 0.84
Myc-induced liver tumors in transgenic zebrafish can regress in tp53 null mutation. PLoS One (2015) 0.83
Mesoporous silica nanoparticles as a compound delivery system in zebrafish embryos. Int J Nanomedicine (2012) 0.83
Host Contributions to Construction of Three Device-Associated Candida albicans Biofilms. Infect Immun (2015) 0.82
The ESX-5 System of Pathogenic Mycobacteria Is Involved In Capsule Integrity and Virulence through Its Substrate PPE10. PLoS Pathog (2016) 0.82
Non-invasive imaging of disseminated candidiasis in zebrafish larvae. J Vis Exp (2012) 0.82
Activation of NF-κB protein prevents the transition from juvenile ovary to testis and promotes ovarian development in zebrafish. J Biol Chem (2012) 0.81
Maternal pak4 expression is required for primitive myelopoiesis in zebrafish. Mech Dev (2012) 0.79
Retinoic acid signaling plays a restrictive role in zebrafish primitive myelopoiesis. PLoS One (2012) 0.79
Zebrafish scube1 (signal peptide-CUB (complement protein C1r/C1s, Uegf, and Bmp1)-EGF (epidermal growth factor) domain-containing protein 1) is involved in primitive hematopoiesis. J Biol Chem (2012) 0.78
iniBAC induction Is Vitamin B12- and MutAB-dependent in Mycobacterium marinum. J Biol Chem (2016) 0.77
Pou5f1/Oct4 promotes cell survival via direct activation of mych expression during zebrafish gastrulation. PLoS One (2014) 0.77
A zebrafish model of inflammatory lymphangiogenesis. Biol Open (2015) 0.76
Type VII secretion--mycobacteria show the way. Nat Rev Microbiol (2007) 4.45
Genomic regulatory blocks encompass multiple neighboring genes and maintain conserved synteny in vertebrates. Genome Res (2007) 3.11
PPE and PE_PGRS proteins of Mycobacterium marinum are transported via the type VII secretion system ESX-5. Mol Microbiol (2009) 2.68
Genomic regulatory blocks underlie extensive microsynteny conservation in insects. Genome Res (2007) 2.44
Deep sequencing of the zebrafish transcriptome response to mycobacterium infection. Mol Immunol (2009) 2.42
Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death. PLoS Pathog (2012) 2.39
ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria. Cell Microbiol (2012) 1.99
Zebrafish embryos as a model host for the real time analysis of Salmonella typhimurium infections. Cell Microbiol (2003) 1.98
A specific secretion system mediates PPE41 transport in pathogenic mycobacteria. Mol Microbiol (2006) 1.97
Single-molecule imaging of the H-ras membrane-anchor reveals domains in the cytoplasmic leaflet of the cell membrane. Biophys J (2004) 1.95
Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model. J Pathol (2012) 1.93
Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3. Proc Natl Acad Sci U S A (2009) 1.93
Large-scale enhancer detection in the zebrafish genome. Development (2005) 1.88
Direct visualization by cryo-EM of the mycobacterial capsular layer: a labile structure containing ESX-1-secreted proteins. PLoS Pathog (2010) 1.76
A star with stripes: zebrafish as an infection model. Trends Microbiol (2004) 1.76
Expression analysis of the Toll-like receptor and TIR domain adaptor families of zebrafish. Mol Immunol (2004) 1.73
The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system. Proc Natl Acad Sci U S A (2013) 1.68
Transcriptome profiling and functional analyses of the zebrafish embryonic innate immune response to Salmonella infection. J Immunol (2009) 1.65
Transgenesis in zebrafish with the tol2 transposon system. Methods Mol Biol (2009) 1.61
Host-pathogen interactions made transparent with the zebrafish model. Curr Drug Targets (2011) 1.60
Systematic human/zebrafish comparative identification of cis-regulatory activity around vertebrate developmental transcription factor genes. Dev Biol (2008) 1.56
Characterization of two Pseudomonas putida lipopeptide biosurfactants, putisolvin I and II, which inhibit biofilm formation and break down existing biofilms. Mol Microbiol (2004) 1.55
Morphogenesis underlying the development of the everted teleost telencephalon. Neural Dev (2012) 1.51
A high-throughput screen for tuberculosis progression. PLoS One (2011) 1.48
Model systems for infectious disease and cancer in zebrafish: a report on an EMBO workshop held at the Lorentz Center, Leiden, The Netherlands, July 16-18, 2007. Zebrafish (2007) 1.47
Zebrafish development and regeneration: new tools for biomedical research. Int J Dev Biol (2009) 1.46
Novel aspects of tomato root colonization and infection by Fusarium oxysporum f. sp. radicis-lycopersici revealed by confocal laser scanning microscopic analysis using the green fluorescent protein as a marker. Mol Plant Microbe Interact (2002) 1.45
Disruption of the ESX-5 system of Mycobacterium tuberculosis causes loss of PPE protein secretion, reduction of cell wall integrity and strong attenuation. Mol Microbiol (2012) 1.39
Infection of zebrafish embryos with intracellular bacterial pathogens. J Vis Exp (2012) 1.36
Specificity of the zebrafish host transcriptome response to acute and chronic mycobacterial infection and the role of innate and adaptive immune components. Mol Immunol (2009) 1.35
MyD88 innate immune function in a zebrafish embryo infection model. Infect Immun (2006) 1.35
General secretion signal for the mycobacterial type VII secretion pathway. Proc Natl Acad Sci U S A (2012) 1.34
Single-molecule diffusion measurements of H-Ras at the plasma membrane of live cells reveal microdomain localization upon activation. J Cell Sci (2005) 1.34
The ESX-5 secretion system of Mycobacterium marinum modulates the macrophage response. J Immunol (2008) 1.33
Zebrafish embryos and larvae: a new generation of disease models and drug screens. Birth Defects Res C Embryo Today (2011) 1.32
Zebrafish embryo screen for mycobacterial genes involved in the initiation of granuloma formation reveals a newly identified ESX-1 component. Dis Model Mech (2011) 1.32
Gene expression profiling of the long-term adaptive response to hypoxia in the gills of adult zebrafish. Am J Physiol Regul Integr Comp Physiol (2005) 1.30
Macrophage-specific gene functions in Spi1-directed innate immunity. Blood (2010) 1.30
Mycobacterium marinum strains can be divided into two distinct types based on genetic diversity and virulence. Infect Immun (2004) 1.29
miR-9 controls the timing of neurogenesis through the direct inhibition of antagonistic factors. Dev Cell (2012) 1.29
Composition of the type VII secretion system membrane complex. Mol Microbiol (2012) 1.29
Towards a new combination therapy for tuberculosis with next generation benzothiazinones. EMBO Mol Med (2014) 1.27
Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) protein domains target LipY lipases of pathogenic mycobacteria to the cell surface via the ESX-5 pathway. J Biol Chem (2011) 1.27
Auxin distribution in Lotus japonicus during root nodule development. Plant Mol Biol (2003) 1.27
The heterologous siderophores ferrioxamine B and ferrichrome activate signaling pathways in Pseudomonas aeruginosa. J Bacteriol (2006) 1.26
Transcriptome profiling of adult zebrafish at the late stage of chronic tuberculosis due to Mycobacterium marinum infection. Mol Immunol (2005) 1.23
Characterization of mucosal biofilms on human adenoid tissues. Laryngoscope (2008) 1.21
Primitive duplicate Hox clusters in the European eel's genome. PLoS One (2012) 1.21
Has2 is required upstream of Rac1 to govern dorsal migration of lateral cells during zebrafish gastrulation. Development (2004) 1.19
Mycobacterial secretion systems ESX-1 and ESX-5 play distinct roles in host cell death and inflammasome activation. J Immunol (2011) 1.17
Interactions in the tomato rhizosphere of two Pseudomonas biocontrol strains with the phytopathogenic fungus Fusarium oxysporum f. sp. radicis-lycopersici. Mol Plant Microbe Interact (2003) 1.16
Zebrafish: an integrative system for neurogenomics and neurosciences. Prog Neurobiol (2010) 1.15
Tubercle bacilli rely on a type VII army for pathogenicity. Trends Microbiol (2012) 1.14
meis1 regulates cyclin D1 and c-myc expression, and controls the proliferation of the multipotent cells in the early developing zebrafish eye. Development (2008) 1.14
Do mycobacteria produce endospores? Proc Natl Acad Sci U S A (2009) 1.13
Exonic remnants of whole-genome duplication reveal cis-regulatory function of coding exons. Nucleic Acids Res (2009) 1.13
Comparison of static immersion and intravenous injection systems for exposure of zebrafish embryos to the natural pathogen Edwardsiella tarda. BMC Immunol (2011) 1.12
Discovery of a functional glucocorticoid receptor beta-isoform in zebrafish. Endocrinology (2007) 1.12
A zebrafish high throughput screening system used for Staphylococcus epidermidis infection marker discovery. BMC Genomics (2013) 1.11
Distinct functions for ERK1 and ERK2 in cell migration processes during zebrafish gastrulation. Dev Biol (2008) 1.11
Role of Pseudomonas putida tol-oprL gene products in uptake of solutes through the cytoplasmic membrane. J Bacteriol (2003) 1.11
Transcriptome analysis of the response to chronic constant hypoxia in zebrafish hearts. J Comp Physiol B (2007) 1.09
Candidates for membrane progestin receptors--past approaches and future challenges. Comp Biochem Physiol C Toxicol Pharmacol (2008) 1.09
Single-molecule diffusion reveals similar mobility for the Lck, H-ras, and K-ras membrane anchors. Biophys J (2006) 1.08
Functional analysis of a zebrafish myd88 mutant identifies key transcriptional components of the innate immune system. Dis Model Mech (2013) 1.07
Pathogen recognition and activation of the innate immune response in zebrafish. Adv Hematol (2012) 1.07
Functions of the MAPK family in vertebrate-development. FEBS Lett (2006) 1.07
Segregation of telencephalic and eye-field identities inside the zebrafish forebrain territory is controlled by Rx3. Development (2006) 1.07
ZebraFISH: fluorescent in situ hybridization protocol and three-dimensional imaging of gene expression patterns. Zebrafish (2006) 1.06
New technologies, new findings, and new concepts in the study of vertebrate cis-regulatory sequences. Dev Dyn (2006) 1.06
Genetic analysis of a pH-regulated operon from Rhizobium tropici CIAT899 involved in acid tolerance and nodulation competitiveness. Mol Plant Microbe Interact (2003) 1.05
Exploring the zebrafish embryo as an alternative model for the evaluation of liver toxicity by histopathology and expression profiling. Arch Toxicol (2013) 1.05
Automated whole animal bio-imaging assay for human cancer dissemination. PLoS One (2012) 1.05
Magnetic resonance microscopy of the adult zebrafish. Zebrafish (2006) 1.04
A Novel extracytoplasmic function (ECF) sigma factor regulates virulence in Pseudomonas aeruginosa. PLoS Pathog (2009) 1.04
Specific chaperones for the type VII protein secretion pathway. J Biol Chem (2012) 1.03
Live analysis of endodermal layer formation identifies random walk as a novel gastrulation movement. Curr Biol (2008) 1.03
Zebrafish reward mutants reveal novel transcripts mediating the behavioral effects of amphetamine. Genome Biol (2009) 1.03
Deep sequencing of the innate immune transcriptomic response of zebrafish embryos to Salmonella infection. Fish Shellfish Immunol (2010) 1.03
Characterization of five novel Pseudomonas aeruginosa cell-surface signalling systems. Mol Microbiol (2007) 1.03
Genomic annotation and expression analysis of the zebrafish Rho small GTPase family during development and bacterial infection. Genomics (2005) 1.01
Cis-regulation and chromosomal rearrangement of the fgf8 locus after the teleost/tetrapod split. Dev Biol (2009) 1.01
SecB-like chaperone controls a toxin-antitoxin stress-responsive system in Mycobacterium tuberculosis. Proc Natl Acad Sci U S A (2011) 1.00