Published in Structure on June 01, 2007
Structure of human monoamine oxidase B, a drug target for the treatment of neurological disorders. Nat Struct Biol (2002) 2.30
Insights into the mode of inhibition of human mitochondrial monoamine oxidase B from high-resolution crystal structures. Proc Natl Acad Sci U S A (2003) 1.81
Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis. Sci Transl Med (2012) 1.78
Three-dimensional structure of human monoamine oxidase A (MAO A): relation to the structures of rat MAO A and human MAO B. Proc Natl Acad Sci U S A (2005) 1.65
Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2. J Am Chem Soc (2010) 1.61
Structure-function relationships in flavoenzyme-dependent amine oxidations: a comparison of polyamine oxidase and monoamine oxidase. J Biol Chem (2002) 1.56
Bioactive contaminants leach from disposable laboratory plasticware. Science (2008) 1.42
High-level expression of human liver monoamine oxidase A in Pichia pastoris: comparison with the enzyme expressed in Saccharomyces cerevisiae. Protein Expr Purif (2002) 1.32
Functional role of the "aromatic cage" in human monoamine oxidase B: structures and catalytic properties of Tyr435 mutant proteins. Biochemistry (2006) 1.21
Demonstration of isoleucine 199 as a structural determinant for the selective inhibition of human monoamine oxidase B by specific reversible inhibitors. J Biol Chem (2005) 1.18
Oxygen isotope effects on electron transfer to O2 probed using chemically modified flavins bound to glucose oxidase. J Am Chem Soc (2004) 1.17
Determination of the oligomeric states of human and rat monoamine oxidases in the outer mitochondrial membrane and octyl beta-D-glucopyranoside micelles using pulsed dipolar electron spin resonance spectroscopy. Biochemistry (2008) 1.08
Crystal structures of monoamine oxidase B in complex with four inhibitors of the N-propargylaminoindan class. J Med Chem (2004) 1.08
Crystal structure of human monoamine oxidase B, a drug target enzyme monotopically inserted into the mitochondrial outer membrane. FEBS Lett (2004) 1.04
Structures of human monoamine oxidase B complexes with selective noncovalent inhibitors: safinamide and coumarin analogs. J Med Chem (2007) 1.03
Ability of tetrahydrobiopterin analogues to support catalysis by inducible nitric oxide synthase: formation of a pterin radical is required for enzyme activity. Biochemistry (2003) 0.99
Nitrogen kinetic isotope effects for the monoamine oxidase B-catalyzed oxidation of benzylamine and (1,1-(2)H2)benzylamine: nitrogen rehybridization and CH bond cleavage are not concerted. J Am Chem Soc (2011) 0.96
Binding of rasagiline-related inhibitors to human monoamine oxidases: a kinetic and crystallographic analysis. J Med Chem (2005) 0.93
High-level expression and purification of rat monoamine oxidase A (MAO A) in Pichia pastoris: comparison with human MAO A. Protein Expr Purif (2009) 0.91
Phentermine inhibition of recombinant human liver monoamine oxidases A and B. Biochem Pharmacol (2002) 0.88
Inactivation of purified human recombinant monoamine oxidases A and B by rasagiline and its analogues. J Med Chem (2004) 0.88
Characterization of detergent purified recombinant rat liver monoamine oxidase B expressed in Pichia pastoris. Protein Expr Purif (2008) 0.87
Comparison of the structural properties of the active site cavities of human and rat monoamine oxidase A and B in their soluble and membrane-bound forms. Biochemistry (2007) 0.87
Lights and shadows on monoamine oxidase inhibition in neuroprotective pharmacological therapies. Curr Top Med Chem (2011) 0.87
Synthesis and characterization of a collagen model delta-O-phosphohydroxylysine-containing peptide. Anal Biochem (2002) 0.87
Precursor of ether phospholipids is synthesized by a flavoenzyme through covalent catalysis. Proc Natl Acad Sci U S A (2012) 0.86
Human and rat monoamine oxidase-A are differentially inhibited by (S)-4-alkylthioamphetamine derivatives: insights from molecular modeling studies. Bioorg Med Chem (2007) 0.85
Structural comparison of human monoamine oxidases A and B: mass spectrometry monitoring of cysteine reactivities. J Biol Chem (2003) 0.85
Interactions of monoamine oxidases with the antiepileptic drug zonisamide: specificity of inhibition and structure of the human monoamine oxidase B complex. J Med Chem (2010) 0.84
The 'gating' residues Ile199 and Tyr326 in human monoamine oxidase B function in substrate and inhibitor recognition. FEBS J (2011) 0.84
Molecular Insights into Human Monoamine Oxidase B Inhibition by the Glitazone Anti-Diabetes Drugs. ACS Med Chem Lett (2011) 0.83
Factors involved in the assembly of a functional molybdopyranopterin center in recombinant Comamonas acidovorans xanthine dehydrogenase. Eur J Biochem (2003) 0.83
Structural and mechanistic studies of arylalkylhydrazine inhibition of human monoamine oxidases A and B. Biochemistry (2008) 0.82
²H kinetic isotope effects and pH dependence of catalysis as mechanistic probes of rat monoamine oxidase A: comparisons with the human enzyme. Biochemistry (2011) 0.82
Inhibition of monoamine oxidase by (E)-styrylisatin analogues. Bioorg Med Chem Lett (2009) 0.81
Structural properties of human monoamine oxidases A and B. Int Rev Neurobiol (2011) 0.81
Demonstration of peroxodiferric intermediate in M-ferritin ferroxidase reaction using rapid freeze-quench Mössbauer, resonance Raman, and XAS spectroscopies. Methods Enzymol (2002) 0.81
Catalytic and inhibitor binding properties of zebrafish monoamine oxidase (zMAO): comparisons with human MAO A and MAO B. Comp Biochem Physiol B Biochem Mol Biol (2011) 0.81
Serine 209 resides within a putative p38(MAPK) consensus motif and regulates monoamine oxidase-A activity. J Neurochem (2009) 0.81
Dual role of FMN in flavodoxin function: electron transfer cofactor and modulation of the protein-protein interaction surface. Biochim Biophys Acta (2009) 0.81
Expression of zebrafish (Danio rerio) monoamine oxidase (MAO) in Pichia pastoris: purification and comparison with human MAO A and MAO B. Protein Expr Purif (2010) 0.81
Mutagenic probes of the role of Ser209 on the cavity shaping loop of human monoamine oxidase A. FEBS J (2009) 0.80
Potentiation of ligand binding through cooperative effects in monoamine oxidase B. J Biol Chem (2010) 0.80
Topological probes of monoamine oxidases A and B in rat liver mitochondria: inhibition by TEMPO-substituted pargyline analogues and inactivation by proteolysis. Biochemistry (2011) 0.79
Polystyrene microbridges used in sitting-drop crystallization release 1,4-diphenyl-2-butene, a novel inhibitor of human MAO B. Acta Crystallogr D Biol Crystallogr (2003) 0.78
Development of spin-labeled pargyline analogues as specific inhibitors of human monoamine oxidases A and B. Biochemistry (2009) 0.78
2-Arylthiomorpholine derivatives as potent and selective monoamine oxidase B inhibitors. Bioorg Med Chem (2010) 0.78
Structural and mechanistic studies of mofegiline inhibition of recombinant human monoamine oxidase B. J Med Chem (2008) 0.77
Truncated FAD synthetase for direct biocatalytic conversion of riboflavin and analogs to their corresponding flavin mononucleotides. Protein Eng Des Sel (2013) 0.75
High-level expression and characterization of a highly functional Comamonas acidovorans xanthine dehydrogenase in Pseudomonas aeruginosa. Protein Expr Purif (2004) 0.75