Published in J Med Chem on October 04, 2007
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Palladium-catalyzed substitution of (coumarinyl)methyl acetates with C-, N-, and S-nucleophiles. Beilstein J Org Chem (2012) 0.77
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Synthesis, molecular modeling, and in vitro screening of monoamine oxidase inhibitory activities of some novel hydrazone derivatives. J Neural Transm (Vienna) (2013) 0.76
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Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA. Cell Res (2011) 4.55
Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency. Nature (2002) 4.21
Accuracy improvement for identifying translation initiation sites in microbial genomes. Bioinformatics (2004) 4.16
In vitro studies with recombinant Plasmodium falciparum apical membrane antigen 1 (AMA1): production and activity of an AMA1 vaccine and generation of a multiallelic response. Infect Immun (2002) 4.02
T-cadherin is a receptor for hexameric and high-molecular-weight forms of Acrp30/adiponectin. Proc Natl Acad Sci U S A (2004) 3.90
Phase 1 clinical trial of apical membrane antigen 1: an asexual blood-stage vaccine for Plasmodium falciparum malaria. Infect Immun (2005) 3.72
Dendritic cell apoptosis in the maintenance of immune tolerance. Science (2006) 3.33
MED: a new non-supervised gene prediction algorithm for bacterial and archaeal genomes. BMC Bioinformatics (2007) 3.03
Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans. DNA Res (2004) 2.95
Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54. Nat Genet (2010) 2.95
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An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background. Nature (2012) 2.35
Structure of human monoamine oxidase B, a drug target for the treatment of neurological disorders. Nat Struct Biol (2002) 2.30
A novel mammalian flavin-dependent histone demethylase. J Biol Chem (2009) 2.25
The survival of motor neurons protein determines the capacity for snRNP assembly: biochemical deficiency in spinal muscular atrophy. Mol Cell Biol (2005) 2.23
Phase 1 vaccine trial of Pvs25H: a transmission blocking vaccine for Plasmodium vivax malaria. Vaccine (2005) 2.21
Human histone demethylase LSD1 reads the histone code. J Biol Chem (2005) 2.14
A randomized stepped care intervention trial targeting posttraumatic stress disorder for surgically hospitalized injury survivors. Ann Surg (2013) 2.13
Crystal structure of a Baeyer-Villiger monooxygenase. Proc Natl Acad Sci U S A (2004) 2.07
A family of Acrp30/adiponectin structural and functional paralogs. Proc Natl Acad Sci U S A (2004) 2.06
Genetics of metabolic variations between Yersinia pestis biovars and the proposal of a new biovar, microtus. J Bacteriol (2004) 2.04
Acute care clinical indicators associated with discharge outcomes in children with severe traumatic brain injury. Crit Care Med (2014) 2.04
Structural basis of LSD1-CoREST selectivity in histone H3 recognition. J Biol Chem (2007) 1.92
NF-κB inhibition delays DNA damage-induced senescence and aging in mice. J Clin Invest (2012) 1.91
De novo assembly and characterisation of the transcriptome during seed development, and generation of genic-SSR markers in peanut (Arachis hypogaea L.). BMC Genomics (2012) 1.90
A national US study of posttraumatic stress disorder, depression, and work and functional outcomes after hospitalization for traumatic injury. Ann Surg (2008) 1.89
Structure and functionality in flavivirus NS-proteins: perspectives for drug design. Antiviral Res (2009) 1.87
HIF-1α and HIF-2α correlate with migration and invasion in gastric cancer. Cancer Biol Ther (2010) 1.83
Histone demethylation catalysed by LSD1 is a flavin-dependent oxidative process. FEBS Lett (2005) 1.82
Identification and characterization of novel amphioxus microRNAs by Solexa sequencing. Genome Biol (2009) 1.82
Insights into the mode of inhibition of human mitochondrial monoamine oxidase B from high-resolution crystal structures. Proc Natl Acad Sci U S A (2003) 1.81
Variations in rates of tracheostomy in the critically ill trauma patient. Crit Care Med (2006) 1.79
Structural basis for benzothiazinone-mediated killing of Mycobacterium tuberculosis. Sci Transl Med (2012) 1.78
Loss of splicing factor ASF/SF2 induces G2 cell cycle arrest and apoptosis, but inhibits internucleosomal DNA fragmentation. Genes Dev (2005) 1.76
Potential energy landscape and robustness of a gene regulatory network: toggle switch. PLoS Comput Biol (2007) 1.75
Identification of Staphylococcus aureus and determination of its methicillin resistance by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Anal Chem (2002) 1.70
Guideline Adherence and Hospital Costs in Pediatric Severe Traumatic Brain Injury. Pediatr Crit Care Med (2016) 1.69
Three-dimensional structure of human monoamine oxidase A (MAO A): relation to the structures of rat MAO A and human MAO B. Proc Natl Acad Sci U S A (2005) 1.65
C. elegans mitochondrial factor WAH-1 promotes phosphatidylserine externalization in apoptotic cells through phospholipid scramblase SCRM-1. Nat Cell Biol (2007) 1.63
X-ray imaging of shock waves generated by high-pressure fuel sprays. Science (2002) 1.63
Self-directed self-assembly of nanoparticle/copolymer mixtures. Nature (2005) 1.62
Biochemical, structural, and biological evaluation of tranylcypromine derivatives as inhibitors of histone demethylases LSD1 and LSD2. J Am Chem Soc (2010) 1.61
The crucial step in ether phospholipid biosynthesis: structural basis of a noncanonical reaction associated with a peroxisomal disorder. Structure (2007) 1.59
Structure-function relationships in flavoenzyme-dependent amine oxidations: a comparison of polyamine oxidase and monoamine oxidase. J Biol Chem (2002) 1.56
Salicylihalamide A inhibits the V0 sector of the V-ATPase through a mechanism distinct from bafilomycin A1. J Biol Chem (2004) 1.56
HDAC6 controls the kinetics of platelet activation. Blood (2012) 1.54
LSD1: oxidative chemistry for multifaceted functions in chromatin regulation. Trends Biochem Sci (2008) 1.54
A highly specific mechanism of histone H3-K4 recognition by histone demethylase LSD1. J Biol Chem (2006) 1.53
DNA microarray analysis of genome dynamics in Yersinia pestis: insights into bacterial genome microevolution and niche adaptation. J Bacteriol (2004) 1.52
Estimating the reproductive numbers for the 2008-2009 cholera outbreaks in Zimbabwe. Proc Natl Acad Sci U S A (2011) 1.49
A nationwide US study of post-traumatic stress after hospitalization for physical injury. Psychol Med (2007) 1.49
National variability in intracranial pressure monitoring and craniotomy for children with moderate to severe traumatic brain injury. Neurosurgery (2013) 1.48
Glioma virotherapy: effects of innate immune suppression and increased viral replication capacity. Cancer Res (2006) 1.47
The impact of an intensivist-model ICU on trauma-related mortality. Ann Surg (2006) 1.46
TFIID and human mediator coactivator complexes assemble cooperatively on promoter DNA. Genes Dev (2002) 1.45
The tale of protein lysine acetylation in the cytoplasm. J Biomed Biotechnol (2010) 1.44
An investigation of the effects of nanosize delivery system for antisense oligonucleotide on esophageal squamous cancer cells. Cancer Biol Ther (2008) 1.44
Expression of malaria transmission-blocking vaccine antigen Pfs25 in Pichia pastoris for use in human clinical trials. Vaccine (2003) 1.43
Intrinsic noise, dissipation cost, and robustness of cellular networks: the underlying energy landscape of MAPK signal transduction. Proc Natl Acad Sci U S A (2008) 1.43
Configuration-dependent diffusion can shift the kinetic transition state and barrier height of protein folding. Proc Natl Acad Sci U S A (2007) 1.42
Bioactive contaminants leach from disposable laboratory plasticware. Science (2008) 1.42
Intraoperative adherence to a low tidal volume ventilation strategy in critically ill patients with preexisting acute lung injury. J Crit Care (2011) 1.40
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism. Cell Res (2010) 1.36
Snapshots of enzymatic Baeyer-Villiger catalysis: oxygen activation and intermediate stabilization. J Biol Chem (2011) 1.35
Protein microarray for profiling antibody responses to Yersinia pestis live vaccine. Infect Immun (2005) 1.35
Multiscaled exploration of coupled folding and binding of an intrinsically disordered molecular recognition element in measles virus nucleoprotein. Proc Natl Acad Sci U S A (2013) 1.34
Structure and function of human erythrocyte pyruvate kinase. Molecular basis of nonspherocytic hemolytic anemia. J Biol Chem (2002) 1.34
Vitamin C transporter Slc23a1 links renal reabsorption, vitamin C tissue accumulation, and perinatal survival in mice. J Clin Invest (2010) 1.33
Disability 3, 12, and 24 months after traumatic brain injury among children and adolescents. Pediatrics (2011) 1.33
Revealing the moonlighting role of NADP in the structure of a flavin-containing monooxygenase. Proc Natl Acad Sci U S A (2008) 1.33
ThermoFAD, a Thermofluor-adapted flavin ad hoc detection system for protein folding and ligand binding. FEBS J (2009) 1.32
Complete genome sequence of the type strain Pseudomonas stutzeri CGMCC 1.1803. J Bacteriol (2011) 1.32
High-level expression of human liver monoamine oxidase A in Pichia pastoris: comparison with the enzyme expressed in Saccharomyces cerevisiae. Protein Expr Purif (2002) 1.32
Too Costly To Be Ill: Healthcare Access and Health-Seeking Behaviours among Rural-to-Urban Migrants in China. World Health Popul (2006) 1.32
Crystal structure of the catalytic domain of Haspin, an atypical kinase implicated in chromatin organization. Proc Natl Acad Sci U S A (2009) 1.31
Quantifying robustness and dissipation cost of yeast cell cycle network: the funneled energy landscape perspectives. Biophys J (2007) 1.31
Fully human monoclonal antibodies antagonizing the glucagon receptor improve glucose homeostasis in mice and monkeys. J Pharmacol Exp Ther (2009) 1.29
Vasopressor use and effect on blood pressure after severe adult traumatic brain injury. Neurocrit Care (2011) 1.29
Genotypic variants at 2q33 and risk of esophageal squamous cell carcinoma in China: a meta-analysis of genome-wide association studies. Hum Mol Genet (2012) 1.28
Microarray analysis of temperature-induced transcriptome of Yersinia pestis. Microbiol Immunol (2004) 1.28
Expression of the Necator americanus hookworm larval antigen Na-ASP-2 in Pichia pastoris and purification of the recombinant protein for use in human clinical trials. Vaccine (2005) 1.28
Salinomycin inhibits osteosarcoma by targeting its tumor stem cells. Cancer Lett (2011) 1.27
Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity. Blood (2007) 1.27
Characterization of the 3a protein of SARS-associated coronavirus in infected vero E6 cells and SARS patients. J Mol Biol (2004) 1.26
Single molecule conformational dynamics of adenylate kinase: energy landscape, structural correlations, and transition state ensembles. J Am Chem Soc (2008) 1.26
Multiple pathways guide oxygen diffusion into flavoenzyme active sites. Proc Natl Acad Sci U S A (2009) 1.25
Influence of comorbidities and age on outcome following burn injury in older adults. J Burn Care Res (2009) 1.25
Structural insights into the mechanism of amine oxidation by monoamine oxidases A and B. Arch Biochem Biophys (2007) 1.23
Regulation of the lifespan in dendritic cell subsets. Mol Immunol (2007) 1.23