Published in J Biol Chem on June 14, 2007
Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells. PLoS Biol (2009) 2.16
Ischemic neurons prevent vascular regeneration of neural tissue by secreting semaphorin 3A. Blood (2011) 2.02
Semaphorin 3A is an endogenous angiogenesis inhibitor that blocks tumor growth and normalizes tumor vasculature in transgenic mouse models. J Clin Invest (2009) 1.56
Successful inhibition of tumor development by specific class-3 semaphorins is associated with expression of appropriate semaphorin receptors by tumor cells. PLoS One (2008) 1.42
Neuropilins are multifunctional coreceptors involved in tumor initiation, growth, metastasis and immunity. Oncotarget (2012) 1.37
Integrin and growth factor receptor alliance in angiogenesis. Cell Biochem Biophys (2008) 1.31
Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects. Dev Biol (2008) 1.29
Erk5 activation elicits a vasoprotective endothelial phenotype via induction of Kruppel-like factor 4 (KLF4). J Biol Chem (2010) 1.25
Angiogenesis and its targeting in rheumatoid arthritis. Vascul Pharmacol (2009) 1.24
Semaphorin3a regulates endothelial cell number and podocyte differentiation during glomerular development. Development (2009) 1.20
Signal transduction in vasculogenesis and developmental angiogenesis. Int J Dev Biol (2011) 1.17
Extracellular inhibitors, repellents, and semaphorin/plexin/MICAL-mediated actin filament disassembly. Cytoskeleton (Hoboken) (2011) 1.12
Corneal nerves in health and disease. Surv Ophthalmol (2014) 1.12
New insights in synovial angiogenesis. Joint Bone Spine (2009) 1.12
Neuropilin receptors guide distinct phases of sensory and motor neuronal segmentation. Development (2009) 1.11
Regulation of immune cell responses by semaphorins and their receptors. Cell Mol Immunol (2010) 1.08
The role of semaphorins and their receptors in vascular development and cancer. Exp Cell Res (2013) 1.07
Semaphorin signaling in angiogenesis, lymphangiogenesis and cancer. Cell Res (2011) 1.06
Correlating global gene regulation to angiogenesis in the developing chick extra-embryonic vascular system. PLoS One (2009) 1.05
The neurovascular relation in oxygen-induced retinopathy. Mol Vis (2008) 1.05
Expression and function of semaphorin 3A and its receptors in human monocyte-derived macrophages. Hum Immunol (2009) 1.04
Semaphorins and their receptors in lung cancer. Cancer Lett (2008) 1.02
Integration of repulsive guidance cues generates avascular zones that shape mammalian blood vessels. Circ Res (2011) 1.01
Semaphorins in angiogenesis and tumor progression. Cold Spring Harb Perspect Med (2012) 0.99
Neuropilins: expression and roles in the epithelium. Int J Exp Pathol (2012) 0.98
Receptor complexes for each of the Class 3 Semaphorins. Front Cell Neurosci (2012) 0.97
Viral infection, inflammation and schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry (2012) 0.96
Angiogenesis in rheumatoid arthritis. Autoimmunity (2009) 0.95
Expression of VEGF and semaphorin genes define subgroups of triple negative breast cancer. PLoS One (2013) 0.94
Pulmonary epithelial neuropilin-1 deletion enhances development of cigarette smoke-induced emphysema. Am J Respir Crit Care Med (2009) 0.93
Neuropilin-1 mediates myeloid cell chemoattraction and influences retinal neuroimmune crosstalk. J Clin Invest (2014) 0.92
Runx2 promotes both osteoblastogenesis and novel osteoclastogenic signals in ST2 mesenchymal progenitor cells. Osteoporos Int (2011) 0.92
Semaphorin 3A inactivation suppresses ischemia-reperfusion-induced inflammation and acute kidney injury. Am J Physiol Renal Physiol (2014) 0.91
Semaphorin-3D and semaphorin-3E inhibit the development of tumors from glioblastoma cells implanted in the cortex of the brain. PLoS One (2012) 0.91
Neuropilins: a new target for cancer therapy. Cancers (Basel) (2011) 0.90
Expression of semaphorin 3A and neuropilin 1 with clinicopathological features and survival in human tongue cancer. Med Oral Patol Oral Cir Bucal (2012) 0.87
A class III semaphorin (Sema3e) inhibits mouse osteoblast migration and decreases osteoclast formation in vitro. Calcif Tissue Int (2012) 0.84
Decreased expression of SEMA3A is associated with poor prognosis in gastric carcinoma. Int J Clin Exp Pathol (2014) 0.84
Semaphorin 3A contributes to distal pulmonary epithelial cell differentiation and lung morphogenesis. PLoS One (2011) 0.84
Semaphorin3A elevates vascular permeability and contributes to cerebral ischemia-induced brain damage. Sci Rep (2015) 0.84
Semaphorin3A immunohistochemical expression in human meningiomas: correlation with the microvessel density. Virchows Arch (2009) 0.83
Peripheral nerve regeneration is delayed in neuropilin 2-deficient mice. J Neurosci Res (2008) 0.83
Inhibition of pathological retinal neovascularization by semaphorin 3A. Mol Vis (2013) 0.83
NRP1 function and targeting in neurovascular development and eye disease. Prog Retin Eye Res (2016) 0.82
Genome wide screen identifies microsatellite markers associated with acute adverse effects following radiotherapy in cancer patients. BMC Med Genet (2010) 0.81
Targeting Angiogenesis in Rheumatoid Arthritis. Curr Rheumatol Rev (2008) 0.81
Genetic Identification of SEMA3F as an Antilymphangiogenic Metastasis Suppressor Gene in Head and Neck Squamous Carcinoma. Cancer Res (2015) 0.81
A perspective on the role of class III semaphorin signaling in central nervous system trauma. Front Cell Neurosci (2014) 0.80
Expression of pro- and anti-angiogenic factors during the formation of the periocular vasculature and development of the avian cornea. Dev Dyn (2013) 0.79
An image-based RNAi screen identifies SH3BP1 as a key effector of Semaphorin 3E-PlexinD1 signaling. J Cell Biol (2014) 0.79
Emerging roles of Semaphorins in the regulation of epithelial and endothelial junctions. Tissue Barriers (2013) 0.78
Interplay of neuropilin-1 and semaphorin 3A after partial hepatectomy in rats. World J Gastroenterol (2012) 0.77
Spontaneous reversion of the angiogenic phenotype to a nonangiogenic and dormant state in human tumors. Mol Cancer Res (2014) 0.77
Sema-3A indirectly disrupts the regeneration process of goldfish optic nerve after controlled injury. Graefes Arch Clin Exp Ophthalmol (2010) 0.77
Association Between Three SNPs and Thromboangiitis Obliterans in Xinjiang Uyghur Population. Genet Test Mol Biomarkers (2016) 0.76
FoxP1 stimulates angiogenesis by repressing the inhibitory guidance protein semaphorin 5B in endothelial cells. PLoS One (2013) 0.76
The role of the semaphorins in cancer. Cell Adh Migr (2016) 0.75
Inflammation and Lymphedema Are Exacerbated and Prolonged by Neuropilin 2 Deficiency. Am J Pathol (2016) 0.75
Neuropilins and liver. World J Gastroenterol (2015) 0.75
Neurovascular cross talk in diabetic retinopathy: Pathophysiological roles and therapeutic implications. Am J Physiol Heart Circ Physiol (2016) 0.75
A Sema3C Mutant Resistant to Cleavage by Furin (FR-Sema3C) Inhibits Choroidal Neovascularization. PLoS One (2016) 0.75
Neuropilin 1 Receptor Is Up-Regulated in Dysplastic Epithelium and Oral Squamous Cell Carcinoma. Am J Pathol (2016) 0.75
The global transcriptional response of isolated human islets of langerhans to glucagon-like Peptide-1 receptor agonist liraglutide. ISRN Endocrinol (2012) 0.75
Semaphorin4A Is Cytotoxic to Oligodendrocytes and Is Elevated in Microglia and Multiple Sclerosis. ASN Neuro (2015) 0.75
Allosteric inhibition of lysyl oxidase-like-2 impedes the development of a pathologic microenvironment. Nat Med (2010) 3.44
The semaphorins: versatile regulators of tumour progression and tumour angiogenesis. Nat Rev Cancer (2008) 2.95
Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration. Blood (2006) 1.88
Lysyl oxidase-related protein-1 promotes tumor fibrosis and tumor progression in vivo. Cancer Res (2003) 1.88
Functional interaction of VEGF-C and VEGF-D with neuropilin receptors. FASEB J (2006) 1.79
Neuropilin-1 and neuropilin-2 enhance VEGF121 stimulated signal transduction by the VEGFR-2 receptor. FASEB J (2006) 1.75
The neuropilins: multifunctional semaphorin and VEGF receptors that modulate axon guidance and angiogenesis. Trends Cardiovasc Med (2002) 1.70
Semaphorin-3F is an inhibitor of tumor angiogenesis. Cancer Res (2004) 1.70
The interaction of Neuropilin-1 and Neuropilin-2 with tyrosine-kinase receptors for VEGF. Adv Exp Med Biol (2002) 1.43
Successful inhibition of tumor development by specific class-3 semaphorins is associated with expression of appropriate semaphorin receptors by tumor cells. PLoS One (2008) 1.42
Abnormal deposition of collagen around hepatocytes in Wilson's disease is associated with hepatocyte specific expression of lysyl oxidase and lysyl oxidase like protein-2. J Hepatol (2005) 1.41
Enhancing the vascularization of three-dimensional porous alginate scaffolds by incorporating controlled release basic fibroblast growth factor microspheres. J Biomed Mater Res A (2003) 1.41
Neuropilin-1-VEGFR-2 complexing requires the PDZ-binding domain of neuropilin-1. J Biol Chem (2008) 1.38
The neuropilins and their role in tumorigenesis and tumor progression. Cancer Lett (2006) 1.30
Semaphorins in cancer. Front Biosci (2005) 1.29
Semaphorin-3B is an angiogenesis inhibitor that is inactivated by furin-like pro-protein convertases. Cancer Res (2008) 1.26
Oncogenic transformation induces tumor angiogenesis: a role for PAR1 activation. FASEB J (2003) 1.14
A novel asymmetric 3D in-vitro assay for the study of tumor cell invasion. BMC Cancer (2009) 1.13
Plexin-A4 promotes tumor progression and tumor angiogenesis by enhancement of VEGF and bFGF signaling. Blood (2011) 1.08
Tumour growth inhibition and anti-metastatic activity of a mutated furin-resistant Semaphorin 3E isoform. EMBO Mol Med (2012) 1.05
Aberrant expression of neuropilin-1 and -2 in human pancreatic cancer cells. Clin Cancer Res (2004) 1.02
Integration of repulsive guidance cues generates avascular zones that shape mammalian blood vessels. Circ Res (2011) 1.01
Semaphorin 3A is a marker for disease activity and a potential immunoregulator in systemic lupus erythematosus. Arthritis Res Ther (2012) 0.99
Semaphorins in angiogenesis and tumor progression. Cold Spring Harb Perspect Med (2012) 0.99
Neuropilin-1-dependent regulation of EGF-receptor signaling. Cancer Res (2012) 0.95
Semaphorin signaling in vascular and tumor biology. Adv Exp Med Biol (2007) 0.95
Analysis of endogenous peptides bound by soluble MHC class I molecules: a novel approach for identifying tumor-specific antigens. Eur J Immunol (2002) 0.94
Pro-angiogenic cytokines and their role in tumor angiogenesis. Cancer Metastasis Rev (2006) 0.92
Semaphorin-3D and semaphorin-3E inhibit the development of tumors from glioblastoma cells implanted in the cortex of the brain. PLoS One (2012) 0.91
The chemorepulsive axon guidance protein semaphorin3A is a constituent of perineuronal nets in the adult rodent brain. Mol Cell Neurosci (2013) 0.91
VEGF162, a new heparin-binding vascular endothelial growth factor splice form that is expressed in transformed human cells. J Biol Chem (2003) 0.90
Neuropilin-2 is a novel marker expressed in pancreatic islet cells and endocrine pancreatic tumours. J Pathol (2002) 0.89
Stress-induced cholinergic signaling promotes inflammation-associated thrombopoiesis. Blood (2005) 0.87
Segregation of arterial and venous markers in subpopulations of blood islands before vessel formation. Dev Dyn (2005) 0.86
Lysyl oxidase-like-2 promotes tumour angiogenesis and is a potential therapeutic target in angiogenic tumours. Carcinogenesis (2013) 0.86
The enzymatic activity of lysyl oxidas-like-2 (LOXL2) is not required for LOXL2-induced inhibition of keratinocyte differentiation. J Biol Chem (2011) 0.85
Receptor activity modifying protein-3 mediates the protumorigenic activity of lysyl oxidase-like protein-2. FASEB J (2010) 0.82
HVEGF165 increases survival of transplanted hepatocytes within portal radicles: suggested mechanism for early cell engraftment. Cell Transplant (2005) 0.79
Sema-3A indirectly disrupts the regeneration process of goldfish optic nerve after controlled injury. Graefes Arch Clin Exp Ophthalmol (2010) 0.77