Biscembranoids and their probable biogenetic precursor from the Hainan soft coral Sarcophyton tortuosum.

Bioactive natural products from Chinese marine flora and fauna. Acta Pharmacol Sin (2012) 0.88

Circular dichroism calculation for natural products. J Nat Med (2013) 0.87

Lobophytones O-T, new biscembranoids and cembranoid from soft coral Lobophytum pauciflorum. Mar Drugs (2010) 0.87

Glaucumolides A and B, Biscembranoids with New Structural Type from a Cultured Soft Coral Sarcophyton glaucum. Sci Rep (2015) 0.85

Biscembranoids and Cembranoids from the Soft Coral Sarcophyton elegans. Mar Drugs (2017) 0.75

Cytotoxic Effects of Sarcophyton sp. Soft Corals-Is There a Correlation to Their NMR Fingerprints? Mar Drugs (2017) 0.75

Overriding imatinib resistance with a novel ABL kinase inhibitor. Science (2004) 11.83

Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays. J Med Chem (2004) 7.33

Prevalence of chronic obstructive pulmonary disease in China: a large, population-based survey. Am J Respir Crit Care Med (2007) 4.82

Evolutionary dynamics of gene and isoform regulation in Mammalian tissues. Science (2012) 4.52

Ciliary proteins link basal body polarization to planar cell polarity regulation. Nat Genet (2007) 3.79

Identification of new diamine scaffolds with activity against Mycobacterium tuberculosis. J Med Chem (2006) 3.75

Quantitative 3D video microscopy of HIV transfer across T cell virological synapses. Science (2009) 3.69

Effect of carbocisteine on acute exacerbation of chronic obstructive pulmonary disease (PEACE Study): a randomised placebo-controlled study. Lancet (2008) 3.62

Math1-driven GFP expression in the developing nervous system of transgenic mice. Gene Expr Patterns (2003) 3.42

Distinct microRNA expression profiles in acute myeloid leukemia with common translocations. Proc Natl Acad Sci U S A (2008) 3.13

Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation. Development (2006) 2.96

miR-21 plays a pivotal role in gastric cancer pathogenesis and progression. Lab Invest (2008) 2.87

Wnt5a functions in planar cell polarity regulation in mice. Dev Biol (2007) 2.85

Sequence of human immunodeficiency virus type 1 (HIV-1) Gag localization and oligomerization monitored with live confocal imaging of a replication-competent, fluorescently tagged HIV-1. J Virol (2007) 2.52

Identification of the immunodominant protein and other proteins of the Bacillus anthracis exosporium. J Bacteriol (2003) 2.48

Neuregulin-1/erbB-activation improves cardiac function and survival in models of ischemic, dilated, and viral cardiomyopathy. J Am Coll Cardiol (2006) 2.37

Cryo-EM study of the chromatin fiber reveals a double helix twisted by tetranucleosomal units. Science (2014) 2.37

Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway. Nat Genet (2005) 2.36

Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development. PLoS Genet (2008) 2.29

Identification of a new antitubercular drug candidate, SQ109, from a combinatorial library of 1,2-ethylenediamines. J Antimicrob Chemother (2005) 2.08

Determination of substrate motifs for human Chk1 and hCds1/Chk2 by the oriented peptide library approach. J Biol Chem (2002) 2.06

Breaching the DNA damage checkpoint via PF-00477736, a novel small-molecule inhibitor of checkpoint kinase 1. Mol Cancer Ther (2008) 2.04

2-aminothiazole as a novel kinase inhibitor template. Structure-activity relationship studies toward the discovery of N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (dasatinib, BMS-354825) as a potent pan-Src kinase inhibitor. J Med Chem (2006) 1.94

Large-scale data integration framework provides a comprehensive view on glioblastoma multiforme. Genome Med (2010) 1.94

Novel oligosaccharide side chains of the collagen-like region of BclA, the major glycoprotein of the Bacillus anthracis exosporium. J Biol Chem (2004) 1.92

Three circadian clock genes Per2, Arntl, and Npas2 contribute to winter depression. Ann Med (2007) 1.77

Human immunodeficiency virus (HIV)-1 infects human hepatic stellate cells and promotes collagen I and monocyte chemoattractant protein-1 expression: implications for the pathogenesis of HIV/hepatitis C virus-induced liver fibrosis. Hepatology (2010) 1.72

Orientation within the exosporium and structural stability of the collagen-like glycoprotein BclA of Bacillus anthracis. J Bacteriol (2005) 1.71

HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis. Proc Natl Acad Sci U S A (2013) 1.70

Phase I trial of lenalidomide and CCI-779 in patients with relapsed multiple myeloma: evidence for lenalidomide-CCI-779 interaction via P-glycoprotein. J Clin Oncol (2011) 1.65

The expression of CRM1 is associated with prognosis in human osteosarcoma. Oncol Rep (2009) 1.64

Comparative analysis of mesenchymal stem cells from bone marrow, cartilage, and adipose tissue. Stem Cells Dev (2008) 1.64

Synthesis and electromagnetic, microwave absorbing properties of core-shell Fe3O4-poly(3, 4-ethylenedioxythiophene) microspheres. ACS Appl Mater Interfaces (2011) 1.62

Asymptomatic patients of chronic obstructive pulmonary disease in China. Chin Med J (Engl) (2010) 1.62

Planar cell polarity signaling in vertebrates. Bioessays (2007) 1.62

Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia. Cancer Cell (2012) 1.61

Up-regulation of a HOXA-PBX3 homeobox-gene signature following down-regulation of miR-181 is associated with adverse prognosis in patients with cytogenetically abnormal AML. Blood (2012) 1.59

Validity of Asthma Control Test in Chinese patients. Chin Med J (Engl) (2007) 1.58

Barriers to TB care for rural-to-urban migrant TB patients in Shanghai: a qualitative study. Trop Med Int Health (2009) 1.53

Activation of vascular endothelial growth factor through reactive oxygen species mediates 20-hydroxyeicosatetraenoic acid-induced endothelial cell proliferation. J Pharmacol Exp Ther (2007) 1.53

A new kalihinol diterpene from the Hainan sponge Acanthella sp. Arch Pharm Res (2009) 1.51

Chronic obstructive pulmonary disease in the absence of chronic bronchitis in China. Respirology (2010) 1.50

Results of trimodality therapy in patients with stage IIIA (N2-bulky) and stage IIIB non-small-cell lung cancer. Clin Lung Cancer (2009) 1.50

Cochlear gap junctions coassembled from Cx26 and 30 show faster intercellular Ca2+ signaling than homomeric counterparts. Am J Physiol Cell Physiol (2005) 1.49

miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia. Nat Commun (2012) 1.49

Substrate-friendly synthesis of metal oxide nanostructures using a hotplate. Small (2006) 1.45

Expression of Islet1 marks the sensory and neuronal lineages in the mammalian inner ear. J Comp Neurol (2004) 1.45

Restoration of connexin26 protein level in the cochlea completely rescues hearing in a mouse model of human connexin30-linked deafness. Proc Natl Acad Sci U S A (2007) 1.44

Analytical and clinical evaluation of CYFRA 21-1 by electrochemiluminescent immunoassay in head and neck squamous cell carcinoma. J Laryngol Otol (2003) 1.44

ER-alpha36, a novel variant of ER-alpha, is expressed in ER-positive and -negative human breast carcinomas. Anticancer Res (2008) 1.43

Atoh1 directs the formation of sensory mosaics and induces cell proliferation in the postnatal mammalian cochlea in vivo. J Neurosci (2012) 1.43

The efficacy and safety of combination salmeterol (50 microg)/fluticasone propionate (500 microg) inhalation twice daily via accuhaler in Chinese patients with COPD. Chest (2007) 1.43

Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia. Proc Natl Acad Sci U S A (2010) 1.43

miR-135a Suppresses Calcification in Senescent VSMCs by Regulating KLF4/STAT3 Pathway. Curr Vasc Pharmacol (2016) 1.42

Attenuation of late-stage disease in mice infected by the Mycobacterium tuberculosis mutant lacking the SigF alternate sigma factor and identification of SigF-dependent genes by microarray analysis. Infect Immun (2004) 1.41

Clinical, virological, and histopathological manifestations of fatal human infections by avian influenza A(H7N9) virus. Clin Infect Dis (2013) 1.40

Retracted Integrated gene network analysis and text mining revealing PIK3R1 regulated by miR-127 in human bladder cancer. Eur J Med Res (2013) 1.39

Gap junction-mediated intercellular biochemical coupling in cochlear supporting cells is required for normal cochlear functions. Proc Natl Acad Sci U S A (2005) 1.39

Venomous auger snail Hastula (Impages) hectica (Linnaeus, 1758): molecular phylogeny, foregut anatomy and comparative toxinology. J Exp Zool B Mol Dev Evol (2007) 1.39

Development of form and function in the mammalian cochlea. Curr Opin Neurobiol (2009) 1.36

Consistent deregulation of gene expression between human and murine MLL rearrangement leukemias. Cancer Res (2009) 1.35

History and evolution of alpine plants endemic to the Qinghai-Tibetan Plateau: Aconitum gymnandrum (Ranunculaceae). Mol Ecol (2009) 1.34

RNA-dependent inhibition of ribonucleotide reductase is a major pathway for 5-azacytidine activity in acute myeloid leukemia. Blood (2012) 1.33

PBX3 is an important cofactor of HOXA9 in leukemogenesis. Blood (2012) 1.30

Long-acting FGF21 has enhanced efficacy in diet-induced obese mice and in obese rhesus monkeys. Endocrinology (2012) 1.30

Hypomethylation of the IL17RC promoter associates with age-related macular degeneration. Cell Rep (2012) 1.28

WNT signaling promotes Nkx2.5 expression and early cardiomyogenesis via downregulation of Hdac1. Biochim Biophys Acta (2008) 1.27

Pharmacologic ascorbate synergizes with gemcitabine in preclinical models of pancreatic cancer. Free Radic Biol Med (2011) 1.27

De novo assembly and characterization of transcriptome using Illumina paired-end sequencing and identification of CesA gene in ramie (Boehmeria nivea L. Gaud). BMC Genomics (2013) 1.26

A multicenter clinical trial on the diagnostic value of dual-tracer PET/CT in pulmonary lesions using 3'-deoxy-3'-18F-fluorothymidine and 18F-FDG. J Nucl Med (2008) 1.25

Histone tails regulate DNA methylation by allosterically activating de novo methyltransferase. Cell Res (2011) 1.24

The phylogenetic positions of three Basal-hexapod groups (protura, diplura, and collembola) based on ribosomal RNA gene sequences. Mol Biol Evol (2005) 1.24

Primary cilia in planar cell polarity regulation of the inner ear. Curr Top Dev Biol (2008) 1.23

Secondary metabolites from the South China Sea invertebrates: chemistry and biological activity. Curr Med Chem (2006) 1.22

Omarigliptin (MK-3102): a novel long-acting DPP-4 inhibitor for once-weekly treatment of type 2 diabetes. J Med Chem (2014) 1.22

Wnt activity guides facial branchiomotor neuron migration, and involves the PCP pathway and JNK and ROCK kinases. Neural Dev (2009) 1.21

LOX-induced lipid peroxidation mechanism responsible for the detrimental effect of marine diatoms on zooplankton grazers. Chembiochem (2007) 1.21

The role of complex lipids in the synthesis of bioactive aldehydes of the marine diatom Skeletonema costatum. Biochim Biophys Acta (2004) 1.20

TET1 plays an essential oncogenic role in MLL-rearranged leukemia. Proc Natl Acad Sci U S A (2013) 1.19

Line up and listen: Planar cell polarity regulation in the mammalian inner ear. Semin Cell Dev Biol (2009) 1.18

Structure of the variant histone H3.3-H4 heterodimer in complex with its chaperone DAXX. Nat Struct Mol Biol (2012) 1.18

The augertoxins: biochemical characterization of venom components from the toxoglossate gastropod Terebra subulata. Toxicon (2003) 1.18

Structural and stereochemical studies of alpha-methylene-gamma-lactone-bearing cembrane diterpenoids from a south china sea soft coral Lobophytum crassum. J Nat Prod (2008) 1.17

Shaping the mammalian auditory sensory organ by the planar cell polarity pathway. Int J Dev Biol (2007) 1.17

Biogenesis of 3-alkylpyridine alkaloids in the marine mollusc Haminoea orbignyana. Angew Chem Int Ed Engl (2003) 1.17

Characterization of native outer membrane vesicles from lpxL mutant strains of Neisseria meningitidis for use in parenteral vaccination. Infect Immun (2005) 1.17

Factors promoting marine invasions: a chemoecological approach. Proc Natl Acad Sci U S A (2008) 1.15

The HMGB1-TLR4 axis contributes to myocardial ischemia/reperfusion injury via regulation of cardiomyocyte apoptosis. Gene (2013) 1.15

Enhanced levels of prostaglandin E2 and matrix metalloproteinase-2 correlate with the severity of airflow limitation in stable COPD. Respirology (2008) 1.15

Protective effects of necrostatin-1 against concanavalin A-induced acute hepatic injury in mice. Mediators Inflamm (2013) 1.15

Identification of a 24-gene prognostic signature that improves the European LeukemiaNet risk classification of acute myeloid leukemia: an international collaborative study. J Clin Oncol (2013) 1.15

Dimerisation of the UBA domain of p62 inhibits ubiquitin binding and regulates NF-kappaB signalling. J Mol Biol (2009) 1.14

Repeated exposure to propofol potentiates neuroapoptosis and long-term behavioral deficits in neonatal rats. Neurosci Lett (2013) 1.13

Side population in the pancreatic cancer cell lines SW1990 and CFPAC-1 is enriched with cancer stem-like cells. Oncol Rep (2010) 1.13

Synthesis of nitrogen-doped porous carbon nanofibers as an efficient electrode material for supercapacitors. ACS Nano (2012) 1.12

5-(4-Chloro-phen-oxy)-6-isopropyl-3-phenyl-3H-1,2,3-triazolo[4,5-d]pyrimidin-7(6H)-one. Acta Crystallogr Sect E Struct Rep Online (2009) 1.12

Comparative proteomics approach to screening of potential diagnostic and therapeutic targets for oral squamous cell carcinoma. Mol Cell Proteomics (2008) 1.11

Protein kinase A and two phosphatases are components of the inositol 1,4,5-trisphosphate receptor macromolecular signaling complex. J Biol Chem (2002) 1.09