Published in Gene Expr Patterns on August 01, 2003
Isolation of neural stem cells from the postnatal cerebellum. Nat Neurosci (2005) 3.97
Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma. Cancer Cell (2009) 3.11
Notch inhibition induces cochlear hair cell regeneration and recovery of hearing after acoustic trauma. Neuron (2013) 2.90
Wnt5a functions in planar cell polarity regulation in mice. Dev Biol (2007) 2.85
Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo. Nat Biotechnol (2014) 2.75
Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm. J Biol (2004) 2.71
Smaller inner ear sensory epithelia in Neurog 1 null mice are related to earlier hair cell cycle exit. Dev Dyn (2005) 2.71
Differential distribution of stem cells in the auditory and vestibular organs of the inner ear. J Assoc Res Otolaryngol (2006) 2.41
Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors. Nature (2014) 2.24
Epidermal progenitors give rise to Merkel cells during embryonic development and adult homeostasis. J Cell Biol (2009) 2.24
A mouse model of the most aggressive subgroup of human medulloblastoma. Cancer Cell (2012) 2.15
An animal model of MYC-driven medulloblastoma. Cancer Cell (2012) 2.12
Quo vadis, hair cell regeneration? Nat Neurosci (2009) 2.12
Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti. Dev Cell (2009) 2.11
Expression of Prox1 during mouse cochlear development. J Comp Neurol (2006) 1.93
Mechanosensitive hair cell-like cells from embryonic and induced pluripotent stem cells. Cell (2010) 1.89
Molecular profiling reveals synaptic release machinery in Merkel cells. Proc Natl Acad Sci U S A (2004) 1.77
Wnt-responsive Lgr5-expressing stem cells are hair cell progenitors in the cochlea. J Neurosci (2012) 1.71
Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development. Genes Dev (2008) 1.65
Inhibition of Notch activity promotes nonmitotic regeneration of hair cells in the adult mouse utricles. J Neurosci (2011) 1.53
Expression of LHX3 and SOX2 during mouse inner ear development. Gene Expr Patterns (2007) 1.52
The cell biology of touch. J Cell Biol (2010) 1.45
N-myc alters the fate of preneoplastic cells in a mouse model of medulloblastoma. Genes Dev (2009) 1.45
Expression of Islet1 marks the sensory and neuronal lineages in the mammalian inner ear. J Comp Neurol (2004) 1.45
The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1. Nat Neurosci (2009) 1.43
Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma. Genes Dev (2008) 1.42
The regularity of sustained firing reveals two populations of slowly adapting touch receptors in mouse hairy skin. J Neurophysiol (2010) 1.41
HP1alpha guides neuronal fate by timing E2F-targeted genes silencing during terminal differentiation. EMBO J (2007) 1.31
Generation of hair cells in neonatal mice by β-catenin overexpression in Lgr5-positive cochlear progenitors. Proc Natl Acad Sci U S A (2013) 1.31
Spontaneous hair cell regeneration in the neonatal mouse cochlea in vivo. Development (2014) 1.27
Notch signaling alters sensory or neuronal cell fate specification of inner ear stem cells. J Neurosci (2011) 1.27
Fibroblast growth factor blocks Sonic hedgehog signaling in neuronal precursors and tumor cells. Proc Natl Acad Sci U S A (2007) 1.24
Manipulating Robo expression in vivo perturbs commissural axon pathfinding in the chick spinal cord. J Neurosci (2008) 1.24
Bone marrow mesenchymal stem cells are progenitors in vitro for inner ear hair cells. Mol Cell Neurosci (2006) 1.23
BMP signaling is necessary for patterning the sensory and nonsensory regions of the developing mammalian cochlea. J Neurosci (2010) 1.22
Reinnervation of hair cells by auditory neurons after selective removal of spiral ganglion neurons. J Neurobiol (2006) 1.21
Beta-catenin up-regulates Atoh1 expression in neural progenitor cells by interaction with an Atoh1 3' enhancer. J Biol Chem (2009) 1.21
Intrinsic regenerative potential of murine cochlear supporting cells. Sci Rep (2011) 1.20
Stem/progenitor cells derived from the cochlear sensory epithelium give rise to spheres with distinct morphologies and features. J Assoc Res Otolaryngol (2009) 1.20
Computation identifies structural features that govern neuronal firing properties in slowly adapting touch receptors. Elife (2014) 1.19
Insulin-like growth factor 2 is required for progression to advanced medulloblastoma in patched1 heterozygous mice. Cancer Res (2008) 1.18
The challenge of hair cell regeneration. Exp Biol Med (Maywood) (2010) 1.14
Swelling-activated Ca2+ channels trigger Ca2+ signals in Merkel cells. PLoS One (2008) 1.10
Toward a systems biology of mouse inner ear organogenesis: gene expression pathways, patterns and network analysis. Genetics (2007) 1.10
The Atoh1-lineage gives rise to hair cells and supporting cells within the mammalian cochlea. Dev Biol (2013) 1.07
Hey2 functions in parallel with Hes1 and Hes5 for mammalian auditory sensory organ development. BMC Dev Biol (2008) 1.07
Voltage-activated ion channels and Ca(2+)-induced Ca (2+) release shape Ca (2+) signaling in Merkel cells. Pflugers Arch (2008) 1.06
The postnatal accumulation of junctional E-cadherin is inversely correlated with the capacity for supporting cells to convert directly into sensory hair cells in mammalian balance organs. J Neurosci (2011) 1.06
A population of Nestin-expressing progenitors in the cerebellum exhibits increased tumorigenicity. Nat Neurosci (2013) 1.04
Over half the hair cells in the mouse utricle first appear after birth, with significant numbers originating from early postnatal mitotic production in peripheral and striolar growth zones. J Assoc Res Otolaryngol (2012) 1.04
Robust postmortem survival of murine vestibular and cochlear stem cells. J Assoc Res Otolaryngol (2007) 1.04
Transcription factors define the neuroanatomical organization of the medullary reticular formation. Front Neuroanat (2013) 1.03
Isolation of sphere-forming stem cells from the mouse inner ear. Methods Mol Biol (2009) 1.02
Conditional deletion of Atoh1 reveals distinct critical periods for survival and function of hair cells in the organ of Corti. J Neurosci (2013) 0.99
In vivo neuronal subtype-specific targets of Atoh1 (Math1) in dorsal spinal cord. J Neurosci (2011) 0.98
β-Catenin is required for hair-cell differentiation in the cochlea. J Neurosci (2014) 0.98
The genetics of hair cell development and regeneration. Annu Rev Neurosci (2013) 0.97
Notch signaling limits supporting cell plasticity in the hair cell-damaged early postnatal murine cochlea. PLoS One (2013) 0.97
Regulation of EphA8 gene expression by TALE homeobox transcription factors during development of the mesencephalon. Mol Cell Biol (2006) 0.97
Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway. Proc Natl Acad Sci U S A (2014) 0.97
Unipotent, Atoh1+ progenitors maintain the Merkel cell population in embryonic and adult mice. J Cell Biol (2015) 0.96
Neurogenin 1 (Neurog1) expression in the ventral neural tube is mediated by a distinct enhancer and preferentially marks ventral interneuron lineages. Dev Biol (2010) 0.95
Overlapping and distinct pRb pathways in the mammalian auditory and vestibular organs. Cell Cycle (2011) 0.95
Multiple transcriptional mechanisms control Ptf1a levels during neural development including autoregulation by the PTF1-J complex. J Neurosci (2009) 0.94
Conserved regulation of Math5 and Math1 revealed by Math5-GFP transgenes. Mol Cell Neurosci (2007) 0.94
MicroRNAs and epigenetic regulation in the mammalian inner ear: implications for deafness. Mamm Genome (2009) 0.93
Generating mouse models of degenerative diseases using Cre/lox-mediated in vivo mosaic cell ablation. J Clin Invest (2011) 0.92
Inner ear hair cell-like cells from human embryonic stem cells. Stem Cells Dev (2014) 0.89
Statistical analysis and modeling of variance in the SA-I mechanoreceptor response to sustained indentation. Conf Proc IEEE Eng Med Biol Soc (2009) 0.89
Identification of genes concordantly expressed with Atoh1 during inner ear development. Anat Cell Biol (2011) 0.89
Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling. EMBO Rep (2013) 0.89
Neuropilin-2/Semaphorin-3F-mediated repulsion promotes inner hair cell innervation by spiral ganglion neurons. Elife (2015) 0.88
BMPs oppose Math1 in cerebellar development and in medulloblastoma. Genes Dev (2008) 0.88
Diversification and specialization of touch receptors in skin. Cold Spring Harb Perspect Med (2014) 0.88
Changes in the regulation of the Notch signaling pathway are temporally correlated with regenerative failure in the mouse cochlea. Front Cell Neurosci (2015) 0.87
Atoh1 expression and function during auditory hair cell regeneration in post-hatch chickens. Hear Res (2012) 0.87
Engineered knottin peptide enables noninvasive optical imaging of intracranial medulloblastoma. Proc Natl Acad Sci U S A (2013) 0.86
Atoh1 directs hair cell differentiation and survival in the late embryonic mouse inner ear. Dev Biol (2013) 0.86
In Vivo Cochlear Hair Cell Generation and Survival by Coactivation of β-Catenin and Atoh1. J Neurosci (2015) 0.86
Hey1 and Hey2 control the spatial and temporal pattern of mammalian auditory hair cell differentiation downstream of Hedgehog signaling. J Neurosci (2014) 0.86
Distinct roles for fibroblast growth factor signaling in cerebellar development and medulloblastoma. Oncogene (2012) 0.86
Merkel Cells in Somatosensation. Chemosens Percept (2008) 0.86
Functional development of mechanosensitive hair cells in stem cell-derived organoids parallels native vestibular hair cells. Nat Commun (2016) 0.86
Mis-expression of L1 on pre-crossing spinal commissural axons disrupts pathfinding at the ventral midline. Mol Cell Neurosci (2007) 0.86
Guidance of longitudinally projecting axons in the developing central nervous system. Front Mol Neurosci (2012) 0.85
Merkel cells as putative regulatory cells in skin disorders: an in vitro study. PLoS One (2009) 0.85
The role of Atonal transcription factors in the development of mechanosensitive cells. Semin Cell Dev Biol (2013) 0.85
Inhibition of H3K9 methyltransferases G9a/GLP prevents ototoxicity and ongoing hair cell death. Cell Death Dis (2013) 0.85
Kif3a is necessary for initiation and maintenance of medulloblastoma. Carcinogenesis (2013) 0.85
Axon sorting within the spinal cord marginal zone via Robo-mediated inhibition of N-cadherin controls spinocerebellar tract formation. J Neurosci (2012) 0.84
Quantitative High-Resolution Cellular Map of the Organ of Corti. Cell Rep (2015) 0.84
FGFR1-Frs2/3 signalling maintains sensory progenitors during inner ear hair cell formation. PLoS Genet (2014) 0.83
The molecular basis of mechanosensory transduction. Adv Exp Med Biol (2012) 0.83
Aberrant Otx2 expression enhances migration and induces ectopic proliferation of hindbrain neuronal progenitor cells. PLoS One (2012) 0.83
Segregating neural and mechanosensory fates in the developing ear: patterning, signaling, and transcriptional control. Cell Tissue Res (2014) 0.83
Rat Merkel cells are mechanoreceptors and osmoreceptors. PLoS One (2009) 0.83
Cellular targeting for cochlear gene therapy. Adv Otorhinolaryngol (2009) 0.83
EGFR signaling is required for regenerative proliferation in the cochlea: conservation in birds and mammals. Dev Biol (2012) 0.82
NOVA regulates Dcc alternative splicing during neuronal migration and axon guidance in the spinal cord. Elife (2016) 0.81
Sox2 in the differentiation of cochlear progenitor cells. Sci Rep (2016) 0.80
Overriding imatinib resistance with a novel ABL kinase inhibitor. Science (2004) 11.83
Prevalence of chronic obstructive pulmonary disease in China: a large, population-based survey. Am J Respir Crit Care Med (2007) 4.82
Evolutionary dynamics of gene and isoform regulation in Mammalian tissues. Science (2012) 4.52
Isolation of neural stem cells from the postnatal cerebellum. Nat Neurosci (2005) 3.97
Ciliary proteins link basal body polarization to planar cell polarity regulation. Nat Genet (2007) 3.79
Identification of new diamine scaffolds with activity against Mycobacterium tuberculosis. J Med Chem (2006) 3.75
Quantitative 3D video microscopy of HIV transfer across T cell virological synapses. Science (2009) 3.69
Effect of carbocisteine on acute exacerbation of chronic obstructive pulmonary disease (PEACE Study): a randomised placebo-controlled study. Lancet (2008) 3.62
Genetic fate mapping reveals that the caudal ganglionic eminence produces a large and diverse population of superficial cortical interneurons. J Neurosci (2010) 3.61
The role of Math1 in inner ear development: Uncoupling the establishment of the sensory primordium from hair cell fate determination. Development (2002) 3.41
Distinct microRNA expression profiles in acute myeloid leukemia with common translocations. Proc Natl Acad Sci U S A (2008) 3.13
Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation. Development (2006) 2.96
miR-21 plays a pivotal role in gastric cancer pathogenesis and progression. Lab Invest (2008) 2.87
Wnt5a functions in planar cell polarity regulation in mice. Dev Biol (2007) 2.85
Mammalian cochlear supporting cells can divide and trans-differentiate into hair cells. Nature (2006) 2.65
BRCA1 mRNA expression levels predict for overall survival in ovarian cancer after chemotherapy. Clin Cancer Res (2007) 2.58
Mash1 specifies neurons and oligodendrocytes in the postnatal brain. EMBO J (2004) 2.55
Identification of the immunodominant protein and other proteins of the Bacillus anthracis exosporium. J Bacteriol (2003) 2.48
Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4d. Nat Cell Biol (2003) 2.46
Autoregulation of neurogenesis by GDF11. Neuron (2003) 2.40
Cryo-EM study of the chromatin fiber reveals a double helix twisted by tetranucleosomal units. Science (2014) 2.37
Neuregulin-1/erbB-activation improves cardiac function and survival in models of ischemic, dilated, and viral cardiomyopathy. J Am Coll Cardiol (2006) 2.37
Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway. Nat Genet (2005) 2.36
Specification of dorsal spinal cord interneurons. Curr Opin Neurobiol (2003) 2.33
Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development. PLoS Genet (2008) 2.29
Hey2 regulation by FGF provides a Notch-independent mechanism for maintaining pillar cell fate in the organ of Corti. Dev Cell (2009) 2.11
Identification of a new antitubercular drug candidate, SQ109, from a combinatorial library of 1,2-ethylenediamines. J Antimicrob Chemother (2005) 2.08
Determination of substrate motifs for human Chk1 and hCds1/Chk2 by the oriented peptide library approach. J Biol Chem (2002) 2.06
Breaching the DNA damage checkpoint via PF-00477736, a novel small-molecule inhibitor of checkpoint kinase 1. Mol Cancer Ther (2008) 2.04
Outbreak of norovirus infection among river rafters associated with packaged delicatessen meat, Grand Canyon, 2005. Clin Infect Dis (2009) 2.03
Large-scale data integration framework provides a comprehensive view on glioblastoma multiforme. Genome Med (2010) 1.94
Novel oligosaccharide side chains of the collagen-like region of BclA, the major glycoprotein of the Bacillus anthracis exosporium. J Biol Chem (2004) 1.92
Ptf1a determines GABAergic over glutamatergic neuronal cell fate in the spinal cord dorsal horn. Development (2005) 1.90
Three circadian clock genes Per2, Arntl, and Npas2 contribute to winter depression. Ann Med (2007) 1.77
The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene. Mol Cell Biol (2003) 1.77
Cross-regulation of Ngn1 and Math1 coordinates the production of neurons and sensory hair cells during inner ear development. Development (2007) 1.76
A minimal Ksp-cadherin promoter linked to a green fluorescent protein reporter gene exhibits tissue-specific expression in the developing kidney and genitourinary tract. J Am Soc Nephrol (2002) 1.72
A morphogenetic wave of p27Kip1 transcription directs cell cycle exit during organ of Corti development. Development (2006) 1.71
Orientation within the exosporium and structural stability of the collagen-like glycoprotein BclA of Bacillus anthracis. J Bacteriol (2005) 1.71
HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis. Proc Natl Acad Sci U S A (2013) 1.70
The comparative pathology of genetically engineered mouse models for neuroendocrine carcinomas of the lung. J Thorac Oncol (2015) 1.68
Phase I trial of lenalidomide and CCI-779 in patients with relapsed multiple myeloma: evidence for lenalidomide-CCI-779 interaction via P-glycoprotein. J Clin Oncol (2011) 1.65
The expression of CRM1 is associated with prognosis in human osteosarcoma. Oncol Rep (2009) 1.64
Comparative analysis of mesenchymal stem cells from bone marrow, cartilage, and adipose tissue. Stem Cells Dev (2008) 1.64
Ascl1 defines sequentially generated lineage-restricted neuronal and oligodendrocyte precursor cells in the spinal cord. Development (2006) 1.63
Synthesis and electromagnetic, microwave absorbing properties of core-shell Fe3O4-poly(3, 4-ethylenedioxythiophene) microspheres. ACS Appl Mater Interfaces (2011) 1.62
Asymptomatic patients of chronic obstructive pulmonary disease in China. Chin Med J (Engl) (2010) 1.62
Planar cell polarity signaling in vertebrates. Bioessays (2007) 1.62
Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia. Cancer Cell (2012) 1.61
Validity of Asthma Control Test in Chinese patients. Chin Med J (Engl) (2007) 1.58
A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling. Genes Dev (2008) 1.54
In vivo analysis of Ascl1 defined progenitors reveals distinct developmental dynamics during adult neurogenesis and gliogenesis. J Neurosci (2007) 1.54
Barriers to TB care for rural-to-urban migrant TB patients in Shanghai: a qualitative study. Trop Med Int Health (2009) 1.53
Activation of vascular endothelial growth factor through reactive oxygen species mediates 20-hydroxyeicosatetraenoic acid-induced endothelial cell proliferation. J Pharmacol Exp Ther (2007) 1.53
Chronic obstructive pulmonary disease in the absence of chronic bronchitis in China. Respirology (2010) 1.50
Results of trimodality therapy in patients with stage IIIA (N2-bulky) and stage IIIB non-small-cell lung cancer. Clin Lung Cancer (2009) 1.50
Cochlear gap junctions coassembled from Cx26 and 30 show faster intercellular Ca2+ signaling than homomeric counterparts. Am J Physiol Cell Physiol (2005) 1.49
miR-196b directly targets both HOXA9/MEIS1 oncogenes and FAS tumour suppressor in MLL-rearranged leukaemia. Nat Commun (2012) 1.49
Substrate-friendly synthesis of metal oxide nanostructures using a hotplate. Small (2006) 1.45
Expression of Islet1 marks the sensory and neuronal lineages in the mammalian inner ear. J Comp Neurol (2004) 1.45
Restoration of connexin26 protein level in the cochlea completely rescues hearing in a mouse model of human connexin30-linked deafness. Proc Natl Acad Sci U S A (2007) 1.44
Analytical and clinical evaluation of CYFRA 21-1 by electrochemiluminescent immunoassay in head and neck squamous cell carcinoma. J Laryngol Otol (2003) 1.44
ER-alpha36, a novel variant of ER-alpha, is expressed in ER-positive and -negative human breast carcinomas. Anticancer Res (2008) 1.43
Atoh1 directs the formation of sensory mosaics and induces cell proliferation in the postnatal mammalian cochlea in vivo. J Neurosci (2012) 1.43
Aberrant overexpression and function of the miR-17-92 cluster in MLL-rearranged acute leukemia. Proc Natl Acad Sci U S A (2010) 1.43
Distinct domains within Mash1 and Math1 are required for function in neuronal differentiation versus neuronal cell-type specification. Development (2004) 1.43
Ascl1 (Mash1) defines cells with long-term neurogenic potential in subgranular and subventricular zones in adult mouse brain. PLoS One (2011) 1.42
miR-135a Suppresses Calcification in Senescent VSMCs by Regulating KLF4/STAT3 Pathway. Curr Vasc Pharmacol (2016) 1.42
Notch signaling augments the canonical Wnt pathway to specify the size of the otic placode. Development (2008) 1.42
Attenuation of late-stage disease in mice infected by the Mycobacterium tuberculosis mutant lacking the SigF alternate sigma factor and identification of SigF-dependent genes by microarray analysis. Infect Immun (2004) 1.41
Clinical, virological, and histopathological manifestations of fatal human infections by avian influenza A(H7N9) virus. Clin Infect Dis (2013) 1.40
Retracted Integrated gene network analysis and text mining revealing PIK3R1 regulated by miR-127 in human bladder cancer. Eur J Med Res (2013) 1.39
Gap junction-mediated intercellular biochemical coupling in cochlear supporting cells is required for normal cochlear functions. Proc Natl Acad Sci U S A (2005) 1.39
Venomous auger snail Hastula (Impages) hectica (Linnaeus, 1758): molecular phylogeny, foregut anatomy and comparative toxinology. J Exp Zool B Mol Dev Evol (2007) 1.39
Development of form and function in the mammalian cochlea. Curr Opin Neurobiol (2009) 1.36
Consistent deregulation of gene expression between human and murine MLL rearrangement leukemias. Cancer Res (2009) 1.35
History and evolution of alpine plants endemic to the Qinghai-Tibetan Plateau: Aconitum gymnandrum (Ranunculaceae). Mol Ecol (2009) 1.34
Sequential roles for Mash1 and Ngn2 in the generation of dorsal spinal cord interneurons. Development (2005) 1.34
RNA-dependent inhibition of ribonucleotide reductase is a major pathway for 5-azacytidine activity in acute myeloid leukemia. Blood (2012) 1.33
Ascl1 (Mash1) lineage cells contribute to discrete cell populations in CNS architecture. Mol Cell Neurosci (2008) 1.31
Transcriptional autoregulation controls pancreatic Ptf1a expression during development and adulthood. Mol Cell Biol (2008) 1.31
Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways. Proc Natl Acad Sci U S A (2012) 1.31
Long-acting FGF21 has enhanced efficacy in diet-induced obese mice and in obese rhesus monkeys. Endocrinology (2012) 1.30
PBX3 is an important cofactor of HOXA9 in leukemogenesis. Blood (2012) 1.30
Hypomethylation of the IL17RC promoter associates with age-related macular degeneration. Cell Rep (2012) 1.28
Micromirror-scanned dual-axis confocal microscope utilizing a gradient-index relay lens for image guidance during brain surgery. J Biomed Opt (2010) 1.27
WNT signaling promotes Nkx2.5 expression and early cardiomyogenesis via downregulation of Hdac1. Biochim Biophys Acta (2008) 1.27
Pharmacologic ascorbate synergizes with gemcitabine in preclinical models of pancreatic cancer. Free Radic Biol Med (2011) 1.27