Published in Cell Physiol Biochem on January 01, 2007
Regulation of SIRT1 in cellular functions: role of polyphenols. Arch Biochem Biophys (2010) 1.91
Hydrogen peroxide sensing, signaling and regulation of transcription factors. Redox Biol (2014) 1.54
SIRT1 is a redox-sensitive deacetylase that is post-translationally modified by oxidants and carbonyl stress. FASEB J (2010) 1.54
Retracted The effect of marathon on mRNA expression of anti-apoptotic and pro-apoptotic proteins and sirtuins family in male recreational long-distance runners. BMC Physiol (2010) 1.47
Current concepts on oxidative/carbonyl stress, inflammation and epigenetics in pathogenesis of chronic obstructive pulmonary disease. Toxicol Appl Pharmacol (2011) 1.35
Exercise alters SIRT1, SIRT6, NAD and NAMPT levels in skeletal muscle of aged rats. Mech Ageing Dev (2009) 1.29
Deacetylases and NF-kappaB in redox regulation of cigarette smoke-induced lung inflammation: epigenetics in pathogenesis of COPD. Antioxid Redox Signal (2008) 1.26
Redox regulation of SIRT1 in inflammation and cellular senescence. Free Radic Biol Med (2013) 1.17
SIRT1 as a therapeutic target in inflammaging of the pulmonary disease. Prev Med (2011) 1.10
Effects of Kynurenine Pathway Metabolites on Intracellular NAD Synthesis and Cell Death in Human Primary Astrocytes and Neurons. Int J Tryptophan Res (2009) 1.07
Crosstalk between Oxidative Stress and SIRT1: Impact on the Aging Process. Int J Mol Sci (2013) 1.07
Manganese superoxide dismutase: beyond life and death. Amino Acids (2010) 1.06
Oxidative stress and chromatin remodeling in chronic obstructive pulmonary disease and smoking-related diseases. Antioxid Redox Signal (2012) 1.01
A redox-resistant sirtuin-1 mutant protects against hepatic metabolic and oxidant stress. J Biol Chem (2014) 0.93
Histone modifications and alcohol-induced liver disease: are altered nutrients the missing link? World J Gastroenterol (2011) 0.92
SIRT1 inhibits apoptosis of degenerative human disc nucleus pulposus cells through activation of Akt pathway. Age (Dordr) (2012) 0.89
Endogenous oxidative stress prevents telomerase-dependent immortalization of human endothelial cells. Mech Ageing Dev (2010) 0.88
Effects of Kynurenine Pathway Inhibition on NAD Metabolism and Cell Viability in Human Primary Astrocytes and Neurons. Int J Tryptophan Res (2011) 0.87
The Interplay of Reactive Oxygen Species, Hypoxia, Inflammation, and Sirtuins in Cancer Initiation and Progression. Oxid Med Cell Longev (2015) 0.86
Effects of Rhein lysinate on H2O2-induced cellular senescence of human umbilical vascular endothelial cells. Acta Pharmacol Sin (2011) 0.86
H2O2 accumulation mediates differentiation capacity alteration, but not proliferative decline, in senescent human fetal mesenchymal stem cells. Antioxid Redox Signal (2012) 0.86
Watching the watcher: regulation of p53 by mitochondria. Future Oncol (2009) 0.85
Interference between PARPs and SIRT1: a novel approach to healthy ageing? Aging (Albany NY) (2011) 0.85
Ginsenoside Rb1 prevents H2O2-induced HUVEC senescence by stimulating sirtuin-1 pathway. PLoS One (2014) 0.85
Sirtuin Functions in Female Fertility: Possible Role in Oxidative Stress and Aging. Oxid Med Cell Longev (2015) 0.84
Acetylation of the pro-apoptotic factor, p53 in the hippocampus following cerebral ischemia and modulation by estrogen. PLoS One (2011) 0.84
dj-1β regulates oxidative stress, insulin-like signaling and development in Drosophila melanogaster. Cell Cycle (2012) 0.83
NAD⁺-carrying mesoporous silica nanoparticles can prevent oxidative stress-induced energy failures of both rodent astrocytes and PC12 cells. PLoS One (2013) 0.83
SIRT1/PARP1 crosstalk: connecting DNA damage and metabolism. Genome Integr (2013) 0.82
Decreased SIRT2 activity leads to altered microtubule dynamics in oxidatively-stressed neuronal cells: implications for Parkinson's disease. Exp Neurol (2014) 0.82
Effect of high glucose on stress-induced senescence of nucleus pulposus cells of adult rats. Asian Spine J (2015) 0.81
Sirtuins, a promising target in slowing down the ageing process. Biogerontology (2017) 0.80
Redox control of senescence and age-related disease. Redox Biol (2016) 0.79
Accelerated premature stress-induced senescence of young annulus fibrosus cells of rats by high glucose-induced oxidative stress. Int Orthop (2014) 0.79
Preventive effects of epigallocatechin-3-O-gallate against replicative senescence associated with p53 acetylation in human dermal fibroblasts. Oxid Med Cell Longev (2012) 0.79
Ubiquitinated sirtuin 1 (SIRT1) function is modulated during DNA damage-induced cell death and survival. J Biol Chem (2015) 0.78
Metformin and Resveratrol Inhibited High Glucose-Induced Metabolic Memory of Endothelial Senescence through SIRT1/p300/p53/p21 Pathway. PLoS One (2015) 0.78
The long noncoding RNA NRF regulates programmed necrosis and myocardial injury during ischemia and reperfusion by targeting miR-873. Cell Death Differ (2016) 0.78
Protective Effects of Triphala on Dermal Fibroblasts and Human Keratinocytes. PLoS One (2016) 0.77
SIRT1 alleviates senescence of degenerative human intervertebral disc cartilage endo-plate cells via the p53/p21 pathway. Sci Rep (2016) 0.77
Rat Notochordal Cells Undergo Premature Stress-Induced Senescence by High Glucose. Asian Spine J (2015) 0.76
Ionizing radiation induces immediate protein acetylation changes in human cardiac microvascular endothelial cells. J Radiat Res (2015) 0.76
Identification of longevity genes with systems biology approaches. Adv Appl Bioinform Chem (2009) 0.76
Sirt1 expression is associated with CD31 expression in blood cells from patients with chronic obstructive pulmonary disease. Respir Res (2016) 0.75
MAOA-a novel decision maker of apoptosis and autophagy in hormone refractory neuroendocrine prostate cancer cells. Sci Rep (2017) 0.75
Age-Associated Lipidome Changes in Metaphase II Mouse Oocytes. PLoS One (2016) 0.75
Reactive oxygen species are involved in BMP-induced dendritic growth in cultured rat sympathetic neurons. Mol Cell Neurosci (2015) 0.75
SRT1720, a SIRT1 specific activator, protected H2O2-induced senescent endothelium. Am J Transl Res (2016) 0.75
Mechanism of telomere shortening by oxidative stress. Ann N Y Acad Sci (2004) 1.61
Mechanism of NO-mediated oxidative and nitrative DNA damage in hamsters infected with Opisthorchis viverrini: a model of inflammation-mediated carcinogenesis. Nitric Oxide (2004) 1.54
Identification of a glutamic acid repeat polymorphism of ALMS1 as a novel genetic risk marker for early-onset myocardial infarction by genome-wide linkage analysis. Circ Cardiovasc Genet (2013) 1.47
Repeated infection with Opisthorchis viverrini induces accumulation of 8-nitroguanine and 8-oxo-7,8-dihydro-2'-deoxyguanine in the bile duct of hamsters via inducible nitric oxide synthase. Carcinogenesis (2004) 1.25
The role of lysosomal rupture in neuronal death. Prog Neurobiol (2009) 1.22
The role of metals in site-specific DNA damage with reference to carcinogenesis. Free Radic Biol Med (2002) 1.22
Photo-irradiated titanium dioxide catalyzes site specific DNA damage via generation of hydrogen peroxide. Free Radic Res (2004) 1.20
Mechanism of apoptosis induced by doxorubicin through the generation of hydrogen peroxide. Life Sci (2005) 1.20
Role of nitrative and oxidative DNA damage in inflammation-related carcinogenesis. J Biomed Biotechnol (2012) 1.20
Hepatic oxidative DNA damage correlates with iron overload in chronic hepatitis C patients. Free Radic Biol Med (2006) 1.18
First case of New Delhi metallo-beta-lactamase 1-producing Escherichia coli infection in Japan. Clin Infect Dis (2011) 1.13
Nitrative and oxidative DNA damage in oral lichen planus in relation to human oral carcinogenesis. Cancer Sci (2005) 1.10
Base oxidation at 5' site of GG sequence in double-stranded DNA induced by UVA in the presence of xanthone analogues: relationship between the DNA-damaging abilities of photosensitizers and their HOMO energies. Photochem Photobiol (2003) 1.10
DNA intrastrand cross-link at the 5'-GA-3' sequence formed by busulfan and its role in the cytotoxic effect. Cancer Sci (2004) 1.10
Vacuolar H+-ATPase inhibitor induces apoptosis via lysosomal dysfunction in the human gastric cancer cell line MKN-1. J Biochem (2003) 1.09
8-nitroguanine formation in the liver of hamsters infected with Opisthorchis viverrini. Biochem Biophys Res Commun (2003) 1.06
iNOS-dependent DNA damage via NF-kappaB expression in hamsters infected with Opisthorchis viverrini and its suppression by the antihelminthic drug praziquantel. Int J Cancer (2006) 1.06
Urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine in patients with parasite infection and effect of antiparasitic drug in relation to cholangiocarcinogenesis. Cancer Epidemiol Biomarkers Prev (2008) 1.00
Accumulation of 8-nitroguanine in the liver of patients with chronic hepatitis C. J Hepatol (2005) 1.00
Mechanism for generation of hydrogen peroxide and change of mitochondrial membrane potential during rotenone-induced apoptosis. Life Sci (2003) 0.99
Oxidative and nitrative stress in Opisthorchis viverrini-infected hamsters: an indirect effect after praziquantel treatment. Am J Trop Med Hyg (2008) 0.99
Reactive nitrogen species-dependent DNA damage in EBV-associated nasopharyngeal carcinoma: the relation to STAT3 activation and EGFR expression. Int J Cancer (2008) 0.99
Oxidative DNA damage induced by a hydroperoxide derivative of cyclophosphamide. Free Radic Biol Med (2004) 0.98
Pravastatin increases survival and suppresses an increase in myocardial matrix metalloproteinase activity in a rat model of heart failure. Cardiovasc Res (2005) 0.98
Nitrative DNA damage and Oct3/4 expression in urinary bladder cancer with Schistosoma haematobium infection. Biochem Biophys Res Commun (2011) 0.98
Catechins induce oxidative damage to cellular and isolated DNA through the generation of reactive oxygen species. Free Radic Res (2003) 0.98
Oxidative DNA damage in relation to neurotoxicity in the brain of mice exposed to arsenic at environmentally relevant levels. J Occup Health (2005) 0.98
Epstein-Barr virus BHRF1 functions downstream of Bid cleavage and upstream of mitochondrial dysfunction to inhibit TRAIL-induced apoptosis in BJAB cells. Biochem Biophys Res Commun (2002) 0.97
Frequency of bacterial contamination of platelet concentrates before and after introduction of diversion method in Japan. Transfusion (2009) 0.96
Nuclear localization of COX-2 in relation to the expression of stemness markers in urinary bladder cancer. Mediators Inflamm (2012) 0.95
Mechanism of carcinogenesis induced by a veterinary antimicrobial drug, nitrofurazone, via oxidative DNA damage and cell proliferation. Cancer Lett (2004) 0.95
(-)-Epigallocatechin gallate causes oxidative damage to isolated and cellular DNA. Biochem Pharmacol (2003) 0.95
Photosensitized DNA damage and its protection via a novel mechanism. Photochem Photobiol (2007) 0.94
Nitrative and oxidative DNA damage in intrahepatic cholangiocarcinoma patients in relation to tumor invasion. World J Gastroenterol (2005) 0.93
Inflammation-related DNA damage and expression of CD133 and Oct3/4 in cholangiocarcinoma patients with poor prognosis. Free Radic Biol Med (2013) 0.93
Endocrine disruptors that deplete glutathione levels in APC promote Th2 polarization in mice leading to the exacerbation of airway inflammation. Eur J Immunol (2006) 0.92
Evaluation for safety of antioxidant chemopreventive agents. Antioxid Redox Signal (2005) 0.92
Oxidative and nitrative stress caused by subcutaneous implantation of a foreign body accelerates sarcoma development in Trp53+/- mice. Carcinogenesis (2006) 0.92
Accumulation of 8-nitroguanine in human gastric epithelium induced by Helicobacter pylori infection. Biochem Biophys Res Commun (2004) 0.92
Guanine-specific DNA damage induced by gamma-irradiated histone. Biochem J (2005) 0.92
Nitrative and oxidative DNA damage in cervical intraepithelial neoplasia associated with human papilloma virus infection. Cancer Sci (2007) 0.92
Oxidative DNA damage induced by benz[a]anthracene metabolites via redox cycles of quinone and unique non-quinone. Chem Res Toxicol (2003) 0.91
Critical roles for polymerase zeta in cellular tolerance to nitric oxide-induced DNA damage. Cancer Res (2006) 0.91
The role of iNOS-mediated DNA damage in infection- and asbestos-induced carcinogenesis. Ann N Y Acad Sci (2010) 0.90
Proteomic identification of carbonylated proteins in the monkey hippocampus after ischemia-reperfusion. Free Radic Biol Med (2009) 0.89
Procyanidin B2 has anti- and pro-oxidant effects on metal-mediated DNA damage. Free Radic Biol Med (2005) 0.89
Catechol and hydroquinone have different redox properties responsible for their differential DNA-damaging ability. Chem Res Toxicol (2002) 0.89
Promoter hypermethylation of Ras-related GTPase gene RRAD inactivates a tumor suppressor function in nasopharyngeal carcinoma. Cancer Lett (2012) 0.88
Inducible nitric oxide synthase-dependent DNA damage in mouse model of inflammatory bowel disease. Cancer Sci (2005) 0.88
Opisthorchis viverrini antigen induces the expression of Toll-like receptor 2 in macrophage RAW cell line. Int J Parasitol (2005) 0.87
8-Nitroguanine formation in oral leukoplakia, a premalignant lesion. Nitric Oxide (2005) 0.87
Genistein and daidzein induce cell proliferation and their metabolites cause oxidative DNA damage in relation to isoflavone-induced cancer of estrogen-sensitive organs. Biochemistry (2004) 0.87
Metal-mediated oxidative damage to cellular and isolated DNA by gallic acid, a metabolite of antioxidant propyl gallate. Mutat Res (2004) 0.86
Inflammation-induced protein carbonylation contributes to poor prognosis for cholangiocarcinoma. Free Radic Biol Med (2012) 0.86
DNA damage and apoptosis induced by photosensitization of 5,10,15,20-tetrakis (N-methyl-4-pyridyl)-21H,23H-porphyrin via singlet oxygen generation. Photochem Photobiol (2009) 0.86
Romidepsin (FK228), a potent histone deacetylase inhibitor, induces apoptosis through the generation of hydrogen peroxide. Cancer Sci (2010) 0.85
Environmental pollutant tributyltin promotes Th2 polarization and exacerbates airway inflammation. Eur J Immunol (2004) 0.85
Mechanism for manganese enhancement of dopamine-induced oxidative DNA damage and neuronal cell death. Free Radic Biol Med (2006) 0.85
2,4,6-trinitrotoluene-induced reproductive toxicity via oxidative DNA damage by its metabolite. Free Radic Res (2002) 0.84
Attenuation of oxidative stress and cardiac dysfunction by bisoprolol in an animal model of dilated cardiomyopathy. Biochem Biophys Res Commun (2006) 0.84
Mechanism of apoptosis induced by a new topoisomerase inhibitor through the generation of hydrogen peroxide. J Biol Chem (2002) 0.84
Oxidative DNA damage induced by nitrotyrosine, a biomarker of inflammation. Biochem Biophys Res Commun (2004) 0.84
Mechanism of site-specific DNA damage induced by ozone. Mutat Res (2005) 0.84
Oxidative damage to cellular and isolated DNA by homocysteine: implications for carcinogenesis. Oncogene (2003) 0.84