Published in Acta Neuropathol on January 01, 1991
Chronic traumatic encephalopathy in athletes: progressive tauopathy after repetitive head injury. J Neuropathol Exp Neurol (2009) 11.05
Chronic neuropathologies of single and repetitive TBI: substrates of dementia? Nat Rev Neurol (2013) 2.84
Traumatic brain injury and amyloid-β pathology: a link to Alzheimer's disease? Nat Rev Neurosci (2010) 2.34
Axonal pathology in traumatic brain injury. Exp Neurol (2012) 2.20
Widespread τ and amyloid-β pathology many years after a single traumatic brain injury in humans. Brain Pathol (2011) 2.11
The first NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy. Acta Neuropathol (2015) 1.73
Biomarkers of mild traumatic brain injury in cerebrospinal fluid and blood. Nat Rev Neurol (2013) 1.60
Controlled cortical impact traumatic brain injury in 3xTg-AD mice causes acute intra-axonal amyloid-β accumulation and independently accelerates the development of tau abnormalities. J Neurosci (2011) 1.47
Chronic traumatic encephalopathy and athletes. Neurology (2015) 1.45
Acute and chronic traumatic encephalopathies: pathogenesis and biomarkers. Nat Rev Neurol (2013) 1.43
Differential distribution of neurofibrillary tangles in the cerebral cortex of dementia pugilistica and Alzheimer's disease cases. Acta Neuropathol (1992) 1.38
Brain trauma induces massive hippocampal neuron death linked to a surge in beta-amyloid levels in mice overexpressing mutant amyloid precursor protein. Am J Pathol (1998) 1.30
The neuropathology of chronic traumatic encephalopathy. Brain Pathol (2015) 1.24
Immunoexcitotoxicity as a central mechanism in chronic traumatic encephalopathy-A unifying hypothesis. Surg Neurol Int (2011) 1.19
Chronic traumatic encephalopathy: clinical-biomarker correlations and current concepts in pathogenesis. Mol Neurodegener (2014) 1.15
Beta-amyloid deposition in chronic traumatic encephalopathy. Acta Neuropathol (2015) 1.12
Chronic traumatic encephalopathy: a spectrum of neuropathological changes following repetitive brain trauma in athletes and military personnel. Alzheimers Res Ther (2014) 1.11
Concomitant progressive supranuclear palsy and chronic traumatic encephalopathy in a boxer. Acta Neuropathol Commun (2014) 1.09
Frontal cortex neuropathology in dementia pugilistica. J Neurotrauma (2012) 1.08
Review: Contact sport-related chronic traumatic encephalopathy in the elderly: clinical expression and structural substrates. Neuropathol Appl Neurobiol (2011) 1.07
Human tau becomes phosphorylated and forms filamentous deposits when overexpressed in lamprey central neurons in situ. Proc Natl Acad Sci U S A (1997) 1.05
Chronic traumatic encephalopathy in contact sports: a systematic review of all reported pathological cases. PLoS One (2015) 1.05
Traumatic brain injury: cause or risk of Alzheimer's disease? A review of experimental studies. J Neural Transm (Vienna) (2005) 1.03
Inhibition of JNK by a peptide inhibitor reduces traumatic brain injury-induced tauopathy in transgenic mice. J Neuropathol Exp Neurol (2012) 1.02
Marked increase of beta-amyloid(1-42) and amyloid precursor protein in ventricular cerebrospinal fluid after severe traumatic brain injury. J Neurol (2004) 1.01
Acute and chronically increased immunoreactivity to phosphorylation-independent but not pathological TDP-43 after a single traumatic brain injury in humans. Acta Neuropathol (2011) 0.97
Ultrastructural localization of Alzheimer amyloid beta/A4 protein precursor in the cytoplasm of neurons and senile plaque-associated astrocytes. Acta Neuropathol (1992) 0.97
Regulation of human MAPT gene expression. Mol Neurodegener (2015) 0.90
Brain injury, neuroinflammation and Alzheimer's disease. Front Aging Neurosci (2013) 0.89
Dura mater is a potential source of Aβ seeds. Acta Neuropathol (2016) 0.89
Chronic effects of mild neurotrauma: putting the cart before the horse? J Neuropathol Exp Neurol (2015) 0.86
Cerebral beta amyloid deposition in patients with malignant neoplasms: its prevalence with aging and effects of radiation therapy on vascular amyloid. Acta Neuropathol (1995) 0.86
Characterization of Early Pathological Tau Conformations and Phosphorylation in Chronic Traumatic Encephalopathy. J Neuropathol Exp Neurol (2016) 0.85
Cerebral amyloid angiopathy in traumatic brain injury: association with apolipoprotein E genotype. J Neurol Neurosurg Psychiatry (2005) 0.85
Cerebral perfusion and psychometric testing in military amateur boxers and controls. J Neurol Neurosurg Psychiatry (1995) 0.84
Concussion in Chronic Traumatic Encephalopathy. Curr Pain Headache Rep (2015) 0.83
Polypathology and dementia after brain trauma: Does brain injury trigger distinct neurodegenerative diseases, or should they be classified together as traumatic encephalopathy? Exp Neurol (2015) 0.82
Neurochemical profile of dementia pugilistica. J Neurotrauma (2013) 0.82
Cortical Amyloid Burden Differences Across Empirically-Derived Mild Cognitive Impairment Subtypes and Interaction with APOE ɛ4 Genotype. J Alzheimers Dis (2016) 0.81
The response of cerebral cortex to haemorrhagic damage: experimental evidence from a penetrating injury model. PLoS One (2013) 0.80
Color changing photonic crystals detect blast exposure. Neuroimage (2010) 0.78
Chronic traumatic encephalopathy: A paradigm in search of evidence? Lab Invest (2015) 0.76
Role of neurotoxicants and traumatic brain injury in α-synuclein protein misfolding and aggregation. Brain Res Bull (2016) 0.76
Localized cortical chronic traumatic encephalopathy pathology after single, severe axonal injury in human brain. Acta Neuropathol (2016) 0.75
Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem Biophys Res Commun (1984) 20.07
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature (1987) 17.08
Neuronal origin of a cerebral amyloid: neurofibrillary tangles of Alzheimer's disease contain the same protein as the amyloid of plaque cores and blood vessels. EMBO J (1985) 6.24
Formic acid pretreatment enhances immunostaining of cerebral and systemic amyloids. Lab Invest (1987) 4.98
The aftermath of boxing. Psychol Med (1973) 4.92
Paired helical filaments in electron microscopy of Alzheimer's disease. Nature (1963) 4.62
A variety of cerebral amyloid deposits in the brains of the Alzheimer-type dementia demonstrated by beta protein immunostaining. Acta Neuropathol (1988) 4.10
Observations on the brains of non-demented old people. J Neurol Sci (1969) 4.06
Clinico-pathologic studies in dementia: nondemented subjects with pathologically confirmed Alzheimer's disease. Neurology (1988) 3.40
Medical aspects of boxing, particularly from a neurological standpoint. Br Med J (1957) 3.37
Occurrence of neuropil threads in the senile human brain and in Alzheimer's disease: a third location of paired helical filaments outside of neurofibrillary tangles and neuritic plaques. Neurosci Lett (1986) 3.36
A comparative study of modified Bielschowsky, Bodian and thioflavin S stains on Alzheimer's neurofibrillary tangles. Neuropathol Appl Neurobiol (1986) 3.09
Cerebral amyloid angiopathy: incidence and complications in the aging brain. II. The distribution of amyloid vascular changes. Stroke (1984) 2.86
Human amyloidosis, Alzheimer disease and related disorders. Lab Invest (1988) 2.44
The occult aftermath of boxing. J Neurol Neurosurg Psychiatry (1990) 2.41
Quantitative histological studies on the aged human brain. I. Senile plaques and neurofibrillary tangles in "normal" patients. Acta Neuropathol (1970) 2.30
Alzheimer's disease: a study of epidemiological aspects. Ann Neurol (1984) 2.17
Neuropil threads occur in dendrites of tangle-bearing nerve cells. Neuropathol Appl Neurobiol (1988) 2.11
The widespread alteration of neurites in Alzheimer's disease may be unrelated to amyloid deposition. Ann Neurol (1989) 2.07
Ultrastructure of the neuropil threads in the Alzheimer brain: their dendritic origin and accumulation in the senile plaques. Acta Neuropathol (1990) 2.03
Monoclonal antibodies raised against a subsequence of senile plaque core protein react with plaque cores, plaque periphery and cerebrovascular amyloid in Alzheimer's disease. Neurosci Lett (1986) 2.01
Massive somatodendritic sprouting of cortical neurons in Alzheimer's disease. Brain Res (1988) 1.96
Axonal disruption and aberrant localization of tau protein characterize the neuropil pathology of Alzheimer's disease. Ann Neurol (1987) 1.93
Head injury as a risk factor for Alzheimer's disease. Neurology (1985) 1.60
Protein chemical and immunocytochemical studies of meningovascular beta-amyloid protein in Alzheimer's disease and normal aging. Brain Res (1988) 1.59
Morphology and distribution of plaque and related deposits in the brains of Alzheimer's disease and control cases. An immunohistochemical study using amyloid beta-protein antibody. Lab Invest (1989) 1.56
Observations on the pathology of insidious dementia following head injury. J Ment Sci (1959) 1.55
The amyloid deposits in Alzheimer's disease: their nature and pathogenesis. Appl Pathol (1984) 1.49
Tau protein immunoreactivity in dementia of the Alzheimer type. I. Morphology, evolution, distribution, and pathogenetic implications. Lab Invest (1989) 1.40
Brain amyloid in normal aging and cerebral amyloid angiopathy is antigenically related to Alzheimer's disease beta-protein. Am J Pathol (1987) 1.36
Neurofibrillary tangles in some cases of dementia pugilistica share antigens with amyloid beta-protein of Alzheimer's disease. Am J Pathol (1990) 1.30
Posttraumatic premature Alzheimer's disease. Neuropathologic findings and pathogenetic considerations. Arch Neurol (1982) 1.23
Topographical relationship between beta-amyloid and tau protein epitopes in tangle-bearing cells in Alzheimer disease. Proc Natl Acad Sci U S A (1990) 1.22
Dementia in a punch-drunk wife. Lancet (1990) 1.21
Secondary deposition of beta amyloid within extracellular neurofibrillary tangles in Alzheimer-type dementia. Am J Pathol (1991) 1.20
Cerebral amyloid angiopathy in the elderly. J Am Geriatr Soc (1981) 1.13
Post-traumatic Alzheimer's disease: preponderance of a single plaque type. Neuropathol Appl Neurobiol (1991) 1.13
Immunohistochemical characterization of the amyloid deposits and quantitation of pertinent cerebrospinal fluid proteins in hereditary cerebral hemorrhage with amyloidosis. Stroke (1987) 1.06
Neurofibrillary tangles in dementia pugilistica are ubiquitinated. J Neurol Neurosurg Psychiatry (1991) 1.05
Immunocytochemistry of neurofibrillary tangles in dementia pugilistica and Alzheimer's disease: evidence for common genesis. Lancet (1989) 1.04
Senile plaque neurites fail to demonstrate anti-paired helical filament and anti-microtubule-associated protein-tau immunoreactive proteins in the absence of neurofibrillary tangles in the neocortex. Acta Neuropathol (1989) 0.99
Early senile plaques in Alzheimer's disease demonstrated by histochemistry, immunocytochemistry, and electron microscopy. Hum Pathol (1990) 0.97
Organic psychosyndromes due to boxing. Br J Psychiatry (1969) 0.90
Beta-protein deposition: a pathogenetic link between Alzheimer's disease and cerebral amyloid angiopathies. Brain Res (1988) 0.88
The pathobiology of Alzheimer's disease. Annu Rev Med (1989) 0.84
Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem Biophys Res Commun (1984) 20.07
Amyloid deposits and amyloidosis. The beta-fibrilloses (first of two parts). N Engl J Med (1980) 9.38
Alzheimer's disease and Down's syndrome: sharing of a unique cerebrovascular amyloid fibril protein. Biochem Biophys Res Commun (1984) 8.14
Scrapie prions aggregate to form amyloid-like birefringent rods. Cell (1983) 7.92
A perpendicular-anisotropy CoFeB-MgO magnetic tunnel junction. Nat Mater (2010) 7.78
Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43). Neuron (1994) 6.41
Alzheimer's disease: insolubility of partially purified paired helical filaments in sodium dodecyl sulfate and urea. Science (1982) 5.42
Ubiquitin is a component of paired helical filaments in Alzheimer's disease. Science (1987) 5.06
X-ray diffraction studies on amyloid filaments. J Histochem Cytochem (1968) 4.54
Amyloid fibril proteins: proof of homology with immunoglobulin light chains by sequence analyses. Science (1971) 4.27
A variety of cerebral amyloid deposits in the brains of the Alzheimer-type dementia demonstrated by beta protein immunostaining. Acta Neuropathol (1988) 4.10
Amyloid deposits and amyloidosis: the beta-fibrilloses (second of two parts). N Engl J Med (1980) 3.95
Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease. Proc Natl Acad Sci U S A (1993) 3.73
Antibodies to paired helical filaments in Alzheimer's disease do not recognize normal brain proteins. Nature (1983) 3.67
Loss of function of a rice brassinosteroid insensitive1 homolog prevents internode elongation and bending of the lamina joint. Plant Cell (2000) 3.56
Neuritic plaques and cerebrovascular amyloid in Alzheimer disease are antigenically related. Proc Natl Acad Sci U S A (1985) 3.54
Metalloproteinase-mediated release of human Fas ligand. J Exp Med (1995) 3.53
Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of beta-catenin. J Biol Chem (1998) 3.39
Amyloid beta protein (A beta) deposition: A beta 42(43) precedes A beta 40 in Down syndrome. Ann Neurol (1995) 3.34
Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability. J Biol Chem (1999) 3.22
DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability. Mol Cell Biol (1999) 3.17
Creation of "amyloid" fibrils from Bence Jones proteins in vitro. Science (1971) 3.14
Dominant and differential deposition of distinct beta-amyloid peptide species, A beta N3(pE), in senile plaques. Neuron (1995) 2.90
Flexible bronchofiberscope. Keio J Med (1968) 2.82
GM1 ganglioside-bound amyloid beta-protein (A beta): a possible form of preamyloid in Alzheimer's disease. Nat Med (1995) 2.77
Beta-pleated sheet fibrils. A comparison of native amyloid with synthetic protein fibrils. J Histochem Cytochem (1974) 2.69
Lewy bodies are ubiquitinated. A light and electron microscopic immunocytochemical study. Acta Neuropathol (1988) 2.59
Phosphorylated tau protein is integrated into paired helical filaments in Alzheimer's disease. J Biochem (1986) 2.54
Sarin poisoning in Matsumoto, Japan. Lancet (1995) 2.52
Detection of mRNA for the tax1/rex1 gene of human T-cell leukemia virus type I in fresh peripheral blood mononuclear cells of adult T-cell leukemia patients and viral carriers by using the polymerase chain reaction. Proc Natl Acad Sci U S A (1989) 2.49
One of the antigenic determinants of paired helical filaments is related to tau protein. J Biochem (1986) 2.37
Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos. Mol Cell Biol (1998) 2.33
The carboxyl third of tau is tightly bound to paired helical filaments. Neuron (1988) 2.31
SCA17, a novel autosomal dominant cerebellar ataxia caused by an expanded polyglutamine in TATA-binding protein. Hum Mol Genet (2001) 2.30
Glucose intolerance caused by a defect in the entero-insular axis: a study in gastric inhibitory polypeptide receptor knockout mice. Proc Natl Acad Sci U S A (1999) 2.29
Differences between vascular and plaque core amyloid in Alzheimer's disease. J Neurochem (1988) 2.24
Expression of multiple tau isoforms and microtubule bundle formation in fibroblasts transfected with a single tau cDNA. J Cell Biol (1989) 2.24
Amyloidosis: its nature and pathogenesis. Semin Hematol (1973) 2.21
Inorganic polyphosphate and the induction of rpoS expression. Proc Natl Acad Sci U S A (1997) 2.19
The ultrastructure of human amyloid as revealed by the negative staining technique. J Ultrastruct Res (1966) 2.13
Proline-directed and non-proline-directed phosphorylation of PHF-tau. J Biol Chem (1995) 2.09
Mutations in ATP2C1, encoding a calcium pump, cause Hailey-Hailey disease. Nat Genet (2000) 2.09
The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like protein. Neuron (1991) 2.05
Ultrastructure of the neuropil threads in the Alzheimer brain: their dendritic origin and accumulation in the senile plaques. Acta Neuropathol (1990) 2.03
Intracellular generation and accumulation of amyloid beta-peptide terminating at amino acid 42. J Biol Chem (1997) 2.02
Structure-function relationship of the eukaryotic DNA replication factor, proliferating cell nuclear antigen. J Biol Chem (1995) 1.99
A new dipeptide naphthylamidase hydrolyzing glycyl-prolyl-beta-naphthylamide. Histochemie (1966) 1.98
Amyloid, amyloidosis, and amyloidogenesis. Int Rev Exp Pathol (1976) 1.97
Synthesis and antiviral activity evaluation of some aminoadamantane derivatives. J Med Chem (1994) 1.91
Possible relationship of a 36-megadalton Salmonella enteritidis plasmid to virulence in mice. Infect Immun (1985) 1.91
Amino acid sequence of an amyloid fibril protein of unknown origin. J Biol Chem (1972) 1.90
Protein sequence and mass spectrometric analyses of tau in the Alzheimer's disease brain. J Biol Chem (1992) 1.89
Amyloid fibril protein AA: purification and properties of the antigenically related serum component as determined by solid phase radioimmunoassay. J Immunol (1976) 1.89
The gene mutated in adult-onset type II citrullinaemia encodes a putative mitochondrial carrier protein. Nat Genet (1999) 1.87
Isolation of a low-molecular-weight serum component antigenically related to an amyloid fibril protein of unknown origin. Proc Natl Acad Sci U S A (1975) 1.84
Distinct intramembrane cleavage of the beta-amyloid precursor protein family resembling gamma-secretase-like cleavage of Notch. J Biol Chem (2001) 1.83
Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation. Nat Med (1999) 1.82
Reciprocal group I inhibition on triceps surae motoneurons in man. J Neurophysiol (1971) 1.81
Constitutive activation of NF-kappaB in primary adult T-cell leukemia cells. Blood (1999) 1.73
Human beta-galactosidase gene mutations in GM1-gangliosidosis: a common mutation among Japanese adult/chronic cases. Am J Hum Genet (1991) 1.72
Calreticulin functions in vitro as a molecular chaperone for both glycosylated and non-glycosylated proteins. EMBO J (1999) 1.67
Immunohistochemical characterization of cerebrovascular amyloid in 46 autopsied cases using antibodies to beta protein and cystatin C. Stroke (1990) 1.67
Hepatocyte growth factor is essential for amelioration of hyperglycemia in streptozotocin-induced diabetic mice receiving a marginal mass of intrahepatic islet grafts. Transplantation (2000) 1.66
Long-term consequence of endoscopic sphincterotomy for bile duct stones. Gastrointest Endosc (1998) 1.64
cDNA and deduced amino acid sequence of a mouse DNA repair enzyme (APEX nuclease) with significant homology to Escherichia coli exonuclease III. J Biol Chem (1991) 1.64
The immunoglobulin origin of amyloid. Am J Med (1972) 1.64
Brain transglutaminase: in vitro crosslinking of human neurofilament proteins into insoluble polymers. Proc Natl Acad Sci U S A (1982) 1.63
A new G-CSF-supported combination chemotherapy, LSG15, for adult T-cell leukaemia-lymphoma: Japan Clinical Oncology Group Study 9303. Br J Haematol (2001) 1.57
Keratin 14 gene mutations in patients with epidermolysis bullosa simplex. J Invest Dermatol (1995) 1.57
Occipital hypoperfusion in Parkinson's disease without dementia: correlation to impaired cortical visual processing. J Neurol Neurosurg Psychiatry (2003) 1.56
Morphology and distribution of plaque and related deposits in the brains of Alzheimer's disease and control cases. An immunohistochemical study using amyloid beta-protein antibody. Lab Invest (1989) 1.56
Retrograde pancreatography and cholangiography by fiber duodenoscope. Gastroenterology (1970) 1.56
Complexities of DNA base excision repair in mammalian cells. Mol Cells (1997) 1.56
A mutation in the ceruloplasmin gene is associated with systemic hemosiderosis in humans. Nat Genet (1995) 1.54
Effect of apolipoprotein E allele epsilon4 on the initial phase of amyloid beta-protein accumulation in the human brain. Am J Pathol (2000) 1.52
Congophilic angiopathy in the pathogenesis of Alzheimer's degeneration. Ann Pathol (1981) 1.51
Immunocytochemical and ultrastructural studies of Pick's disease. Ann Neurol (1990) 1.51
Structural identity of Bence Jones and amyloid fibril proteins in a patient with plasma cell dyscrasia and amyloidosis. J Clin Invest (1973) 1.51
Sphincter of Oddi motor activity in patients with anomalous pancreaticobiliary junction. Am J Gastroenterol (1991) 1.50
The amyloid deposits in Alzheimer's disease: their nature and pathogenesis. Appl Pathol (1984) 1.49
Ultrastructure of the human carotid body. A perspective on the mode of chemoreception. Circulation (1968) 1.48
The long-term fate of the gallbladder after endoscopic sphincterotomy. Complete follow-up study of 122 patients. Am J Surg (1987) 1.48
Supplemental glutamine augments phagocytosis and reactive oxygen intermediate production by neutrophils and monocytes from postoperative patients in vitro. Nutrition (2000) 1.47
Purification and characterization of Lewy bodies from the brains of patients with diffuse Lewy body disease. Am J Pathol (1996) 1.47
Glutamine-enriched enteral diet enhances bacterial clearance in protected bacterial peritonitis, regardless of glutamine form. JPEN J Parenter Enteral Nutr (1997) 1.46
Human amyloid protein: chemical variability and homogeneity. J Histochem Cytochem (1971) 1.45
The role of mediastinoscopic biopsy in preoperative assessment of lung cancer. J Thorac Cardiovasc Surg (1992) 1.45
Suppression of lung metastasis of B16 mouse melanoma by N-acetylglucosaminyltransferase III gene transfection. Proc Natl Acad Sci U S A (1995) 1.44
Transient hypertension due to adrenal hemorrhage in a patient with von Recklinghausen's disease. Intern Med (1997) 1.44
Aberrant glycosylation of E-cadherin enhances cell-cell binding to suppress metastasis. J Biol Chem (1996) 1.44
Tau in paired helical filaments is functionally distinct from fetal tau: assembly incompetence of paired helical filament-tau. J Neurochem (1993) 1.43
Molecular reorientations in liquid crystals pentyloxybenzylidine hexylanilene (PBHA) and butyloxybenzylidine octylanilene (BBOA). Phys Rev E Stat Nonlin Soft Matter Phys (2004) 1.41
Immunocytochemical and ultrastructural studies of lower motor neurons in amyotrophic lateral sclerosis. Ann Neurol (1990) 1.40
Hailey-Hailey disease is not allelic to Darier's disease. J Invest Dermatol (1994) 1.40
Bilirubin adsorption therapy and subsequent liver transplantation cured severe bilirubin encephalopathy in a long-term survival patient with Crigler-Najjar disease type I. Intern Med (2000) 1.40
State transitions by molecules. Biosystems (1999) 1.40
Requirement for human AP endonuclease 1 for repair of 3'-blocking damage at DNA single-strand breaks induced by reactive oxygen species. Carcinogenesis (2000) 1.40
Hereditary generalized amyloidosis with polyneuropathy. Clinicopathological study of 65 Japanese patients. Brain (1987) 1.39