Current status of tumor M2 pyruvate kinase (tumor M2-PK) as a biomarker of gastrointestinal malignancy.

Tyrosine phosphorylation inhibits PKM2 to promote the Warburg effect and tumor growth. Sci Signal (2009) 5.57

Diagnostic utility of faecal biomarkers in patients with irritable bowel syndrome. World J Gastroenterol (2014) 0.93

Faecal pyruvate kinase isoenzyme type M2 for colorectal cancer screening: a meta-analysis. World J Gastroenterol (2012) 0.93

Identification of annexin A1 as a proinvasive and prognostic factor for lung adenocarcinoma. Clin Exp Metastasis (2011) 0.92

PKM2 inhibitor shikonin suppresses TPA-induced mitochondrial malfunction and proliferation of skin epidermal JB6 cells. Mol Carcinog (2012) 0.90

Pyruvate kinase M2 in blood circulation facilitates tumor growth by promoting angiogenesis. J Biol Chem (2014) 0.88

Linking vitamin B1 with cancer cell metabolism. Cancer Metab (2013) 0.82

Knockdown of PKM2 Suppresses Tumor Growth and Invasion in Lung Adenocarcinoma. Int J Mol Sci (2015) 0.82

Pyruvate kinase M2 is a novel diagnostic marker and predicts tumor progression in human biliary tract cancer. Cancer (2012) 0.81

Phosphorylation of pyruvate kinase M2 and lactate dehydrogenase A by fibroblast growth factor receptor 1 in benign and malignant thyroid tissue. BMC Cancer (2015) 0.80

Targeted proteomics for multiplexed verification of markers of colorectal tumorigenesis. Mol Cell Proteomics (2017) 0.78

A Novel Role for Pyruvate Kinase M2 as a Corepressor for P53 during the DNA Damage Response in Human Tumor Cells. J Biol Chem (2016) 0.75

Prospective evaluation of plasma levels of ANGPT2, TuM2PK, and VEGF in patients with renal cell carcinoma. BMC Urol (2015) 0.75

Glucose metabolic phenotype of pancreatic cancer. World J Gastroenterol (2016) 0.75

Determinant-based classification of acute pancreatitis severity: an international multidisciplinary consultation. Ann Surg (2012) 5.55

Open pancreatic necrosectomy in the multidisciplinary management of postinflammatory necrosis. Ann Surg (2010) 2.97

Mesh fixation at laparoscopic inguinal hernia repair: a meta-analysis comparing tissue glue and tack fixation. World J Surg (2014) 2.66

EGFR and KRAS mutational analysis and their correlation to survival in pancreatic and periampullary cancer. Pancreas (2012) 1.65

European survey of surgical strategies for the management of severe acute pancreatitis. Am J Gastroenterol (2004) 1.56

The liver-first approach to the management of colorectal cancer with synchronous hepatic metastases: a systematic review. JAMA Surg (2013) 1.52

The end of cryotherapy for the treatment of nonresectable hepatic tumors? Ann Surg Oncol (2005) 1.40

Radiofrequency ablation of liver tumours: systematic review. Lancet Oncol (2004) 1.38

Systematic appraisal of the role of metallic endobiliary stents in the treatment of benign bile duct stricture. Ann Surg (2005) 1.30

Systematic appraisal of the management of the major vascular complications of pancreatitis. Am J Surg (2005) 1.22

Role of tumor necrosis factor-alpha in acute pancreatitis: from biological basis to clinical evidence. Shock (2007) 1.13

Markers of angiogenesis in synchronous and in metachronous colorectal hepatic metastases. Ann Surg (2015) 1.08

Understanding the colonic complications of pancreatitis. Pancreatology (2008) 1.04

Cholecystitis after cholecystectomy. J R Soc Med (2002) 1.00

Radiofrequency ablation for locally advanced cancer of the pancreas. JOP (2006) 0.99

Evidence for a central role for selective mesenteric angiography in the management of the major vascular complications of pancreatitis. Am J Surg (2003) 0.98

Quality of life assessment in patients with chronic pancreatitis receiving antioxidant therapy. World J Gastroenterol (2010) 0.95

Radiofrequency ablation of the pancreas. II: Intra-operative ablation of non-resectable pancreatic cancer. A description of technique and initial outcome. JOP (2005) 0.94

Development and validation of an experimental model for the assessment of radiofrequency ablation of pancreatic parenchyma. Pancreas (2005) 0.94

Effects of thalidomide in a mouse model of cerulein-induced acute pancreatitis. Shock (2008) 0.93

TNF-alpha as a therapeutic target in acute pancreatitis--lessons from experimental models. ScientificWorldJournal (2007) 0.90

Diagnostic and prognostic value of plasma tumor M2 pyruvate kinase in periampullary cancer: evidence for a novel biological marker of adverse prognosis. Pancreas (2007) 0.89

Experimental and clinical evidence for modification of hepatic ischaemia-reperfusion injury by N-acetylcysteine during major liver surgery. HPB (Oxford) (2011) 0.89

Centralisation of upper gastrointestinal cancer surgery. Ann R Coll Surg Engl (2007) 0.89

Etanercept attenuates the development of cerulein-induced acute pancreatitis in mice: a comparison with TNF-alpha genetic deletion. Shock (2007) 0.88

Epidermal growth factor receptor in pancreatic cancer. Cancers (Basel) (2011) 0.87

Nutritional and anthropometric assessment of the scope for dietary optimization during staging prior to pancreaticoduodenectomy. JOP (2008) 0.87

Sequential endovascular repair and pancreaticoduodenectomy for abdominal aortic aneurysm copresenting with periampullary cancer. Ann Vasc Surg (2006) 0.83

Inhibition of tyrosine-kinase-mediated cellular signaling by tyrphostins AG 126 and AG556 modulates murine experimental acute pancreatitis. Surgery (2005) 0.82

Current status of laparoscopic biliary bypass in the management of non-resectable peri-ampullary cancer. Pancreatology (2005) 0.82

Drotrecogin alfa (recombinant human activated protein C) in severe acute pancreatitis. Crit Care (2005) 0.82

Intravenous selenium modulates L-arginine-induced experimental acute pancreatitis. JOP (2005) 0.81

The performance of organ dysfunction scores for the early prediction and management of severity in acute pancreatitis: an exploratory phase diagnostic study. Pancreas (2010) 0.80

Green tea polyphenols ameliorate pancreatic injury in cerulein-induced murine acute pancreatitis. Pancreas (2009) 0.80

Insulin protects pancreatic acinar cells from cytosolic calcium overload and inhibition of plasma membrane calcium pump. J Biol Chem (2011) 0.80

Radiofrequency ablation of the pancreas. I: Definition of optimal thermal kinetic parameters and the effect of simulated portal venous circulation in an ex-vivo porcine model. JOP (2005) 0.80

Recombinant human activated protein C (Xigris) attenuates murine cerulein-induced acute pancreatitis via regulation of nuclear factor κB and apoptotic pathways. Pancreas (2012) 0.80

Pathways of care for patients with suspected cancer of the pancreas: a tiered questionnaire-based survey of medical personnel across a single United kingdom Calman-Hine cancer network. JOP (2005) 0.80

Recombinant human activated protein C as a disease modifier in severe acute pancreatitis: systematic review of current evidence. Pancreatology (2012) 0.79

Duodenal duplication cyst with profound elevation of intracystic carbohydrate antigen (CA 19-9) and carcinoembryonic antigen (CEA): a rare but important differential in the diagnosis of cystic tumours of the pancreas. JOP (2006) 0.79

Evaluation of the Manchester classification system for chronic pancreatitis. JOP (2006) 0.78

Contemporary management of perihilar cholangiocarcinoma in a nontransplant hepatopancreatobiliary center. Eur J Gastroenterol Hepatol (2013) 0.78

General surgery in patients with a bleeding diathesis: how we do it. World J Surg (2011) 0.78

Poly(A) cDNA real-time PCR for indicator gene measurement in cancer. Methods Mol Biol (2010) 0.77

Glycolytic ATP fuels the plasma membrane calcium pump critical for pancreatic cancer cell survival. J Biol Chem (2013) 0.77

Cytokine profiles in patients receiving antioxidant therapy within the ANTICIPATE trial. World J Gastroenterol (2013) 0.77

Differential kinetics of plasma CD105 and transforming growth factor beta expression early in human acute pancreatitis. Pancreas (2006) 0.77

Poly(adenylic acid) complementary DNA real-time polymerase chain reaction in pancreatic ductal juice in patients undergoing pancreaticoduodenectomy. Pancreas (2010) 0.77

Quantitative analysis of plasma DNA in severe acute pancreatitis. JOP (2006) 0.76

Contemporary management of infected necrosis complicating severe acute pancreatitis. Crit Care (2006) 0.76

Variance in elective surgery for chronic pancreatitis. JOP (2009) 0.76

Administration of human recombinant activated protein C is not associated with pancreatic parenchymal haemorrhage in L-arginine-induced experimental acute pancreatitis. JOP (2013) 0.76

Pro/con debate: antifungal prophylaxis is important to prevent fungal infection in patients with acute necrotizing pancreatitis receiving broad-spectrum antibiotics. Crit Care (2006) 0.76

Long-term outcome of patients with chronic pancreatitis treated with micronutrient antioxidant therapy. Hepatobiliary Pancreat Dis Int (2017) 0.75

Endoscopic versus surgical treatment for chronic pancreatitis. N Engl J Med (2007) 0.75

Outcome of hepaticojejunostomy without access loop for repair of iatrogenic bile duct injury at laparoscopic cholecystectomy. J Hepatobiliary Pancreat Surg (2007) 0.75

Functional protein C levels during the early phase of clinical acute pancreatitis. Pancreas (2010) 0.75

Contemporary management of pancreatic pseudocysts. Pancreatology (2005) 0.75

Improving definition of the term "synchronous liver metastases" from colorectal cancer. Hepatobiliary Pancreat Dis Int (2016) 0.75

Practical strategies for case selection in minimally invasive necrosectomy. Pancreatology (2008) 0.75

Laparoscopic biliary bypass and current management algorithms for the palliation of malignant obstructive jaundice. Ann Surg Oncol (2004) 0.75

Erratum to: Preventing Inguinodynia After Hernia Surgery: Does the Type of Mesh Matter? World J Surg (2015) 0.75