Published in J Biol Chem on November 29, 2011
Calcium channels and pumps in cancer: changes and consequences. J Biol Chem (2012) 1.49
Reappraisal of xenobiotic-induced, oxidative stress-mediated cellular injury in chronic pancreatitis: a systematic review. World J Gastroenterol (2014) 0.79
Glycolytic ATP fuels the plasma membrane calcium pump critical for pancreatic cancer cell survival. J Biol Chem (2013) 0.77
Insulin protects pancreatic acinar cells from palmitoleic acid-induced cellular injury. J Biol Chem (2014) 0.76
Do Animal Models of Acute Pancreatitis Reproduce Human Disease? Cell Mol Gastroenterol Hepatol (2017) 0.75
AKT/PKB signaling: navigating downstream. Cell (2007) 31.26
Akt stimulates aerobic glycolysis in cancer cells. Cancer Res (2004) 9.35
THE METABOLISM OF TUMORS IN THE BODY. J Gen Physiol (1927) 7.64
Akt-directed glucose metabolism can prevent Bax conformation change and promote growth factor-independent survival. Mol Cell Biol (2003) 3.84
Mitochondria and calcium: from cell signalling to cell death. J Physiol (2000) 3.73
Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak. Mol Cell (2004) 3.62
Insulin-regulatable tissues express a unique insulin-sensitive glucose transport protein. Nature (1988) 3.57
Hypertriglyceridemic pancreatitis: presentation and management. Am J Gastroenterol (2009) 2.79
Acute pancreatitis: bench to the bedside. Gastroenterology (2007) 2.78
Activation of glycogen synthase kinase 3beta disrupts the binding of hexokinase II to mitochondria by phosphorylating voltage-dependent anion channel and potentiates chemotherapy-induced cytotoxicity. Cancer Res (2005) 2.64
Phosphorylation and activation of heart 6-phosphofructo-2-kinase by protein kinase B and other protein kinases of the insulin signaling cascades. J Biol Chem (1997) 2.43
The identification of ATP-citrate lyase as a protein kinase B (Akt) substrate in primary adipocytes. J Biol Chem (2002) 2.36
Phosphoinositide 3-kinase signalling--which way to target? Trends Pharmacol Sci (2003) 2.35
Akt mediates mitochondrial protection in cardiomyocytes through phosphorylation of mitochondrial hexokinase-II. Cell Death Differ (2007) 2.10
The phosphoinositide (PI) 3-kinase family. J Cell Sci (2003) 1.94
Insulin elicits a redistribution of transferrin receptors in 3T3-L1 adipocytes through an increase in the rate constant for receptor externalization. J Biol Chem (1987) 1.75
Phosphatidylinositol 3-kinase-dependent activation of trypsinogen modulates the severity of acute pancreatitis. J Clin Invest (2001) 1.51
Phosphoinositide 3-kinase gamma: a key modulator in inflammation and allergy. Biochem Soc Trans (2003) 1.27
Preferential support of Ca2+ uptake in smooth muscle plasma membrane vesicles by an endogenous glycolytic cascade. FASEB J (1989) 1.25
L-arginine-induced experimental pancreatitis. World J Gastroenterol (2004) 1.20
From acinar cell damage to systemic inflammatory response: current concepts in pancreatitis. Pancreatology (2001) 1.18
Fatty acids, alcohol and fatty acid ethyl esters: toxic Ca2+ signal generation and pancreatitis. Cell Calcium (2009) 1.12
PI3K/Akt/mTOR pathway inhibitors in cancer: a perspective on clinical progress. Curr Med Chem (2010) 1.11
The cancer cell's "power plants" as promising therapeutic targets: an overview. J Bioenerg Biomembr (2007) 1.09
Comparison of endogenous and exogenous sources of ATP in fueling Ca2+ uptake in smooth muscle plasma membrane vesicles. J Gen Physiol (1992) 1.08
Protein-serine kinase from rat epididymal adipose tissue which phosphorylates and activates acetyl-CoA carboxylase. Possible role in insulin action. Biochem J (1990) 1.07
Phosphatidylinositide 3-kinase gamma regulates key pathologic responses to cholecystokinin in pancreatic acinar cells. Gastroenterology (2004) 1.06
Role of Na+/Ca2+ exchange and the plasma membrane Ca2+ pump in hormone-mediated Ca2+ efflux from pancreatic acini. J Membr Biol (1988) 1.05
AKT and oxidative stress team up to kill cancer cells. Cancer Cell (2008) 1.03
Phosphatidylinositol 3-kinase facilitates bile acid-induced Ca(2+) responses in pancreatic acinar cells. Am J Physiol Gastrointest Liver Physiol (2006) 1.01
Differential effects of iodoacetamide and iodoacetate on glycolysis and glutathione metabolism of cultured astrocytes. Front Neuroenergetics (2009) 0.97
Cell death in pancreatitis: effects of alcohol. J Gastroenterol Hepatol (2006) 0.96
Ablation of phosphoinositide 3-kinase-gamma reduces the severity of acute pancreatitis. Am J Pathol (2004) 0.95
Role of growth hormone and insulin-like growth factor-1 in the protective effect of ghrelin in ischemia/reperfusion-induced acute pancreatitis. Growth Horm IGF Res (2006) 0.95
IGF-1 stimulates production of interleukin-10 and inhibits development of caerulein-induced pancreatitis. J Physiol Pharmacol (2003) 0.95
Phosphatidylinositol 3-kinase regulates Ca2+ signaling in pancreatic acinar cells through inhibition of sarco(endo)plasmic reticulum Ca2+-ATPase. Am J Physiol Gastrointest Liver Physiol (2004) 0.93
Gastrointestinal growth factors and hormones have divergent effects on Akt activation. Cell Signal (2009) 0.92
The hormonal regulation of pyruvate dehydrogenase complex. Adv Enzyme Regul (1996) 0.91
Acute inhibition of insulin-stimulated glucose transport by the phosphatase inhibitor, okadaic acid. J Biol Chem (1991) 0.90
The stress response of the exocrine pancreas. Dig Dis (2004) 0.89
Hepatocyte growth factor prevents advanced glycation end products-induced injury and oxidative stress through a PI3K/Akt-dependent pathway in human endothelial cells. Life Sci (2009) 0.88
Oxidant-induced inhibition of the plasma membrane Ca2+-ATPase in pancreatic acinar cells: role of the mitochondria. Am J Physiol Cell Physiol (2008) 0.88
Cholecystokinin fails to promote pancreatic regeneration in diabetic rats following the induction of experimental pancreatitis. Pharmacol Res (2001) 0.88
Oxidant-impaired intracellular Ca2+ signaling in pancreatic acinar cells: role of the plasma membrane Ca2+-ATPase. Am J Physiol Cell Physiol (2007) 0.87
Mitochondrial mechanisms of death responses in pancreatitis. J Gastroenterol Hepatol (2008) 0.87
Plasma membrane calcium pump regulation by metabolic stress. World J Biol Chem (2010) 0.85
Hepatocyte growth factor attenuates pancreatic damage in caerulein-induced pancreatitis in rats. Eur J Pharmacol (2001) 0.85
Recovery of exocrine pancreas six months following pancreatitis induction with L-arginine in streptozotocin-diabetic rats. J Physiol Paris (2000) 0.84
Regulation of glycolytically fueled Ca2+ uptake in smooth muscle plasmalemmal vesicles by phosphorylation. Am J Physiol (1993) 0.81
Insulin is necessary for the hypertrophic effect of cholecystokinin-octapeptide following acute necrotizing experimental pancreatitis. World J Gastroenterol (2004) 0.80
Diminished brain synaptic plasma membrane Ca(2+)-ATPase activity in rats with streptozocin-induced diabetes: association with reduced anesthetic requirements. Life Sci (1994) 0.78
Different genes for obesity are associated with insulin loss of regulation of the membrane (Ca2+ + Mg2+)-ATPase in the obesity syndrome. Lessons from animal models. Int J Obes Relat Metab Disord (1995) 0.77
Role of intravenously infused insulin in treatment of acute pancreatitis. A double-blind study. Scand J Gastroenterol (1975) 0.77
Acute pancreatitis treated with and without addition of insulin. Acta Chir Scand (1977) 0.77
Xanthine oxidase-mediated intracellular oxidative stress in response to cerulein in rat pancreatic acinar cells. Pancreas (1993) 0.76
Decreased activity of (Ca2+ + Mg2+)-adenosine triphosphatase (ATPase) and a hormone-specific defect in insulin regulation of ATPase in kidney basolateral membranes from obese fa/fa rats. Metabolism (1994) 0.76
Hormone-specific defect in insulin regulation of (Ca2+ + Mg2+)-adenosine triphosphatase activity in kidney membranes from streptozocin non-insulin-dependent diabetic rats. Metabolism (1994) 0.76
Determinant-based classification of acute pancreatitis severity: an international multidisciplinary consultation. Ann Surg (2012) 5.55
Cauda equina syndrome. BMJ (2009) 3.69
Open pancreatic necrosectomy in the multidisciplinary management of postinflammatory necrosis. Ann Surg (2010) 2.97
Mesh fixation at laparoscopic inguinal hernia repair: a meta-analysis comparing tissue glue and tack fixation. World J Surg (2014) 2.66
The effect of the new 2010 World Health Organization criteria for semen analyses on male infertility. Fertil Steril (2012) 2.17
Improving the quality of care for infants: a cluster randomized controlled trial. CMAJ (2009) 1.93
EGFR and KRAS mutational analysis and their correlation to survival in pancreatic and periampullary cancer. Pancreas (2012) 1.65
European survey of surgical strategies for the management of severe acute pancreatitis. Am J Gastroenterol (2004) 1.56
The liver-first approach to the management of colorectal cancer with synchronous hepatic metastases: a systematic review. JAMA Surg (2013) 1.52
Patent ductus arteriosus ligation and post-operative hemodynamic instability: case report and framework for enhanced neonatal care. Indian J Pediatr (2010) 1.44
Scalable representations of diseases in biomedical ontologies. J Biomed Semantics (2011) 1.41
The end of cryotherapy for the treatment of nonresectable hepatic tumors? Ann Surg Oncol (2005) 1.40
Radiofrequency ablation of liver tumours: systematic review. Lancet Oncol (2004) 1.38
Systematic appraisal of the role of metallic endobiliary stents in the treatment of benign bile duct stricture. Ann Surg (2005) 1.30
Acute appendicitis with fulminant necrotizing fasciitis in a neonate. J Pediatr Surg (2003) 1.25
Systematic appraisal of the management of the major vascular complications of pancreatitis. Am J Surg (2005) 1.22
Role of tumor necrosis factor-alpha in acute pancreatitis: from biological basis to clinical evidence. Shock (2007) 1.13
Cytosolic Ca(2+) and Ca(2+)-activated Cl(-) current dynamics: insights from two functionally distinct mouse exocrine cells. J Physiol (2002) 1.11
Current status of tumor M2 pyruvate kinase (tumor M2-PK) as a biomarker of gastrointestinal malignancy. Ann Surg Oncol (2007) 1.11
Markers of angiogenesis in synchronous and in metachronous colorectal hepatic metastases. Ann Surg (2015) 1.08
Curcumin induces electrical activity in rat pancreatic beta-cells by activating the volume-regulated anion channel. Biochem Pharmacol (2007) 1.04
Understanding the colonic complications of pancreatitis. Pancreatology (2008) 1.04
Genetic diversity and investigation of polledness in divergent goat populations using 52 088 SNPs. Anim Genet (2012) 1.02
Cholecystitis after cholecystectomy. J R Soc Med (2002) 1.00
Radiofrequency ablation for locally advanced cancer of the pancreas. JOP (2006) 0.99
Pulsed lavage reduces the incidence of radiolucent lines under the tibial tray of Oxford unicompartmental knee arthroplasty: pulsed lavage versus syringe lavage. Int Orthop (2009) 0.99
A role for phosphorylation of inositol 1,4,5-trisphosphate receptors in defining calcium signals induced by Peptide agonists in pancreatic acinar cells. J Biol Chem (2002) 0.98
Evidence for a central role for selective mesenteric angiography in the management of the major vascular complications of pancreatitis. Am J Surg (2003) 0.98
cAMP potentiates ATP-evoked calcium signaling in human parotid acinar cells. J Biol Chem (2004) 0.97
Color opponent retinal ganglion cells in the tammar wallaby retina. J Vis (2002) 0.97
Quality of life assessment in patients with chronic pancreatitis receiving antioxidant therapy. World J Gastroenterol (2010) 0.95
Development and validation of an experimental model for the assessment of radiofrequency ablation of pancreatic parenchyma. Pancreas (2005) 0.94
Effects of thalidomide in a mouse model of cerulein-induced acute pancreatitis. Shock (2008) 0.93
Differential regulation of the apical plasma membrane Ca(2+) -ATPase by protein kinase A in parotid acinar cells. J Biol Chem (2007) 0.92
Advanced maternal age and the outcomes of preterm neonates: a social paradox? Obstet Gynecol (2011) 0.91
Calcium-activated K+ channels increase cell proliferation independent of K+ conductance. Am J Physiol Cell Physiol (2010) 0.90
TNF-alpha as a therapeutic target in acute pancreatitis--lessons from experimental models. ScientificWorldJournal (2007) 0.90
Experimental and clinical evidence for modification of hepatic ischaemia-reperfusion injury by N-acetylcysteine during major liver surgery. HPB (Oxford) (2011) 0.89
Centralisation of upper gastrointestinal cancer surgery. Ann R Coll Surg Engl (2007) 0.89
Diagnostic and prognostic value of plasma tumor M2 pyruvate kinase in periampullary cancer: evidence for a novel biological marker of adverse prognosis. Pancreas (2007) 0.89
Oxidant-induced inhibition of the plasma membrane Ca2+-ATPase in pancreatic acinar cells: role of the mitochondria. Am J Physiol Cell Physiol (2008) 0.88
Etanercept attenuates the development of cerulein-induced acute pancreatitis in mice: a comparison with TNF-alpha genetic deletion. Shock (2007) 0.88
Oxidant-impaired intracellular Ca2+ signaling in pancreatic acinar cells: role of the plasma membrane Ca2+-ATPase. Am J Physiol Cell Physiol (2007) 0.87
Nutritional and anthropometric assessment of the scope for dietary optimization during staging prior to pancreaticoduodenectomy. JOP (2008) 0.87
Epidermal growth factor receptor in pancreatic cancer. Cancers (Basel) (2011) 0.87
Analysis of continuous oxygen saturation data for accurate representation of retinal exposure to oxygen in the preterm infant. Stud Health Technol Inform (2013) 0.85
Modulation of cytosolic calcium signaling by protein kinase A-mediated phosphorylation of inositol 1,4,5-trisphosphate receptors. Biol Res (2004) 0.84
Construction and characterization of a plant transformation-competent BIBAC library of the black Sigatoka-resistant banana Musa acuminata cv. Tuu Gia (AA). Theor Appl Genet (2005) 0.84
Sequential endovascular repair and pancreaticoduodenectomy for abdominal aortic aneurysm copresenting with periampullary cancer. Ann Vasc Surg (2006) 0.83
Inhibition of tyrosine-kinase-mediated cellular signaling by tyrphostins AG 126 and AG556 modulates murine experimental acute pancreatitis. Surgery (2005) 0.82
Heart rate variability as an indicator for morphine pharmacokinetics and pharmacodynamics in critically ill newborn infants. Conf Proc IEEE Eng Med Biol Soc (2014) 0.82
Current status of laparoscopic biliary bypass in the management of non-resectable peri-ampullary cancer. Pancreatology (2005) 0.82
Drotrecogin alfa (recombinant human activated protein C) in severe acute pancreatitis. Crit Care (2005) 0.82
Intravenous selenium modulates L-arginine-induced experimental acute pancreatitis. JOP (2005) 0.81
Possible role of duration of PKC-induced ERK activation in the effects of agonists and phorbol esters on DNA synthesis in Panc-1 cells. J Cell Biochem (2006) 0.81
The performance of organ dysfunction scores for the early prediction and management of severity in acute pancreatitis: an exploratory phase diagnostic study. Pancreas (2010) 0.80
Recombinant human activated protein C (Xigris) attenuates murine cerulein-induced acute pancreatitis via regulation of nuclear factor κB and apoptotic pathways. Pancreas (2012) 0.80
Real-time multidimensional temporal analysis of complex high volume physiological data streams in the neonatal intensive care unit. Stud Health Technol Inform (2013) 0.80
Is routine preoperative 2-dimensional echocardiography necessary for infants with esophageal atresia, omphalocele, or anorectal malformations? J Pediatr Surg (2010) 0.80
Green tea polyphenols ameliorate pancreatic injury in cerulein-induced murine acute pancreatitis. Pancreas (2009) 0.80
Recombinant human activated protein C as a disease modifier in severe acute pancreatitis: systematic review of current evidence. Pancreatology (2012) 0.79
Multiple fatty acid sensing mechanisms operate in enteroendocrine cells: novel evidence for direct mobilization of stored calcium by cytosolic fatty acid. J Biol Chem (2004) 0.78
Contemporary management of perihilar cholangiocarcinoma in a nontransplant hepatopancreatobiliary center. Eur J Gastroenterol Hepatol (2013) 0.78
Evaluation of the Manchester classification system for chronic pancreatitis. JOP (2006) 0.78
General surgery in patients with a bleeding diathesis: how we do it. World J Surg (2011) 0.78
Human calcium-sensing receptor can be suppressed by antisense sequences. Biochem Biophys Res Commun (2003) 0.77
Differential kinetics of plasma CD105 and transforming growth factor beta expression early in human acute pancreatitis. Pancreas (2006) 0.77
Poly(A) cDNA real-time PCR for indicator gene measurement in cancer. Methods Mol Biol (2010) 0.77
Glycolytic ATP fuels the plasma membrane calcium pump critical for pancreatic cancer cell survival. J Biol Chem (2013) 0.77
Cytokine profiles in patients receiving antioxidant therapy within the ANTICIPATE trial. World J Gastroenterol (2013) 0.77
Poly(adenylic acid) complementary DNA real-time polymerase chain reaction in pancreatic ductal juice in patients undergoing pancreaticoduodenectomy. Pancreas (2010) 0.77
Multi-dimensional knowledge translation: enabling health informatics capacity audits using patient journey models. Conf Proc IEEE Eng Med Biol Soc (2008) 0.76
Contemporary management of infected necrosis complicating severe acute pancreatitis. Crit Care (2006) 0.76
Differential regulation of calcium-activated potassium channels by dynamic intracellular calcium signals. J Membr Biol (2010) 0.76
Variance in elective surgery for chronic pancreatitis. JOP (2009) 0.76
Pro/con debate: antifungal prophylaxis is important to prevent fungal infection in patients with acute necrotizing pancreatitis receiving broad-spectrum antibiotics. Crit Care (2006) 0.76
Milk intake and feeding behavior in the first week of life and its relationship to cord blood ghrelin, leptin, and insulin concentrations. Pediatr Res (2007) 0.76
Quantitative analysis of plasma DNA in severe acute pancreatitis. JOP (2006) 0.76
Long-term outcome of patients with chronic pancreatitis treated with micronutrient antioxidant therapy. Hepatobiliary Pancreat Dis Int (2017) 0.75
Endoscopic versus surgical treatment for chronic pancreatitis. N Engl J Med (2007) 0.75
Improving definition of the term "synchronous liver metastases" from colorectal cancer. Hepatobiliary Pancreat Dis Int (2016) 0.75
Laparoscopic biliary bypass and current management algorithms for the palliation of malignant obstructive jaundice. Ann Surg Oncol (2004) 0.75
Designer emission spectra through tailored energy transfer in nanoparticle-doped silica preforms. Opt Lett (2009) 0.75
Functional protein C levels during the early phase of clinical acute pancreatitis. Pancreas (2010) 0.75
Outcome of hepaticojejunostomy without access loop for repair of iatrogenic bile duct injury at laparoscopic cholecystectomy. J Hepatobiliary Pancreat Surg (2007) 0.75
AboutKidsHealth online resource centres: innovation in family health education. AMIA Annu Symp Proc (2007) 0.75
Erratum to: Preventing Inguinodynia After Hernia Surgery: Does the Type of Mesh Matter? World J Surg (2015) 0.75
Integration of drug dosing data with physiological data streams using a cloud computing paradigm. Conf Proc IEEE Eng Med Biol Soc (2013) 0.75
Practical strategies for case selection in minimally invasive necrosectomy. Pancreatology (2008) 0.75
Contemporary management of pancreatic pseudocysts. Pancreatology (2005) 0.75
Next generation neonatal health informatics with Artemis. Stud Health Technol Inform (2011) 0.75
A patient-centric, Internet-based application for the data management of a multi-centre respiratory syncytial virus prophylaxis program. AMIA Annu Symp Proc (2007) 0.75
Wet laboratory tools widely used in plant genomics. Int J Plant Genomics (2010) 0.75