Published in Exp Gerontol on May 18, 2007
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Human cytomegalovirus infection and T cell immunosenescence: a mini review. Mech Ageing Dev (2006) 1.53
No Immune Risk Profile among individuals who reach 100 years of age: findings from the Swedish NONA immune longitudinal study. Exp Gerontol (2007) 1.51
Biomarkers of human immunosenescence: impact of Cytomegalovirus infection. Curr Opin Immunol (2009) 1.51
Direct injection of protamine-protected mRNA: results of a phase 1/2 vaccination trial in metastatic melanoma patients. J Immunother (2009) 1.44
Hallmark features of immunosenescence are absent in familial longevity. J Immunol (2010) 1.43
Myeloid-derived suppressor cells predict survival of patients with advanced melanoma: comparison with regulatory T cells and NY-ESO-1- or melan-A-specific T cells. Clin Cancer Res (2013) 1.43
Multi-parametric phospho-flow cytometry: a crucial tool for T lymphocyte signaling studies. Cytometry A (2013) 1.41
The genetics of human longevity. Ann N Y Acad Sci (2006) 1.30
Infection with cytomegalovirus but not herpes simplex virus induces the accumulation of late-differentiated CD4+ and CD8+ T-cells in humans. J Gen Virol (2011) 1.29
Pretreatment frequency of circulating IL-17+ CD4+ T-cells, but not Tregs, correlates with clinical response to whole-cell vaccination in prostate cancer patients. Int J Cancer (2009) 1.24
Dysregulation of T-cell function in the elderly : scientific basis and clinical implications. Drugs Aging (2005) 1.23
Role of persistent CMV infection in configuring T cell immunity in the elderly. Immun Ageing (2007) 1.21
Immunological biomarkers of ageing in man: changes in both innate and adaptive immunity are associated with health and longevity. Biogerontology (2006) 1.20
Dramatic shifts in circulating CD4 but not CD8 T cell subsets in mild Alzheimer's disease. J Alzheimers Dis (2009) 1.20
Report from the second cytomegalovirus and immunosenescence workshop. Immun Ageing (2011) 1.19
Mechanisms of immunosenescence. Immun Ageing (2009) 1.19
Simultaneous infiltration of polyfunctional effector and suppressor T cells into renal cell carcinomas. Cancer Res (2009) 1.19
CMV and Immunosenescence: from basics to clinics. Immun Ageing (2012) 1.17
Gene expression analysis of mTOR pathway: association with human longevity. Aging Cell (2012) 1.17
An age-related increase in the number of CD8+ T cells carrying receptors for an immunodominant Epstein-Barr virus (EBV) epitope is counteracted by a decreased frequency of their antigen-specific responsiveness. Mech Ageing Dev (2003) 1.17
Immunity, ageing and cancer. Immun Ageing (2008) 1.13
Aging, immunity, and cancer. Discov Med (2011) 1.11
Cytomegalovirus-associated accumulation of late-differentiated CD4 T-cells correlates with poor humoral response to influenza vaccination. Vaccine (2012) 1.10
Potential role of immunosenescence in cancer development. Ann N Y Acad Sci (2010) 1.10
High response rate after intratumoral treatment with interleukin-2: results from a phase 2 study in 51 patients with metastasized melanoma. Cancer (2010) 1.07
Impact of age on T cell signaling: a general defect or specific alterations? Ageing Res Rev (2010) 1.07
Lower proportion of naïve peripheral CD8+ T cells and an unopposed pro-inflammatory response to human Cytomegalovirus proteins in vitro are associated with longer survival in very elderly people. Age (Dordr) (2012) 1.06
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Association of IFN-gamma signal transduction defects with impaired HLA class I antigen processing in melanoma cell lines. Clin Cancer Res (2011) 1.04
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Distinct molecular mechanisms leading to deficient expression of ER-resident aminopeptidases in melanoma. Cancer Immunol Immunother (2010) 1.00
Immune receptor signaling, aging and autoimmunity. Adv Exp Med Biol (2008) 1.00
Impact of CMV and EBV seropositivity on CD8 T lymphocytes in an old population from West-Sicily. Exp Gerontol (2007) 0.99
High frequencies of functionally impaired cytokeratin 18-specific CD8+ T cells in healthy HLA-A2+ donors. Eur J Immunol (2005) 0.98
From bench to bedside and back: the SENIEUR Protocol and the efficacy of influenza vaccination in the elderly. Biogerontology (2008) 0.98
Immunosupportive therapies in aging. Clin Interv Aging (2007) 0.97
Immune profiling of Alzheimer patients. J Neuroimmunol (2011) 0.94
NKp80 defines and stimulates a reactive subset of CD8 T cells. Blood (2008) 0.93
Rudimentary signs of immunosenescence in Cytomegalovirus-seropositive healthy young adults. Age (Dordr) (2013) 0.93
Gene expression changes in long-term culture of T-cell clones: genomic effects of chronic antigenic stress in aging and immunosenescence. Aging Cell (2007) 0.92
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Lymphocyte activation in response to melanoma: interaction of NK-associated receptors and their ligands. Cancer Immunol Immunother (2006) 0.91
The European searchable tumour line database. Cancer Immunol Immunother (2009) 0.91
Age related microsatellite instability in T cells from healthy individuals. Exp Gerontol (2004) 0.91
Compromised interferon gamma (IFN-gamma) production in the elderly to both acute and latent viral antigen stimulation: contribution to the immune risk phenotype? Eur Cytokine Netw (2003) 0.90
Expression of adhesion molecules and ligands for activating and costimulatory receptors involved in cell-mediated cytotoxicity in a large panel of human melanoma cell lines. Cancer Immunol Immunother (2009) 0.90
Induction of HIF-1alpha and the glycolytic pathway alters apoptotic and differentiation profiles of activated human T cells. J Leukoc Biol (2009) 0.89
HER-2/neu-derived peptide 884-899 is expressed by human breast, colorectal and pancreatic adenocarcinomas and is recognized by in-vitro-induced specific CD4(+) T cell clones. Cancer Immunol Immunother (2001) 0.89
HAGE, a cancer/testis antigen with potential for melanoma immunotherapy: identification of several MHC class I/II HAGE-derived immunogenic peptides. Cancer Immunol Immunother (2007) 0.89
Cytomegalovirus seropositivity is associated with glucose regulation in the oldest old. Results from the Leiden 85-plus Study. Immun Ageing (2012) 0.89
Aging affects the proportions of T and B cells in a group of elderly men in a developing country--a pilot study from Pakistan. Age (Dordr) (2012) 0.88
Relationships between cancer and aging: a multilevel approach. Biogerontology (2009) 0.88
Immune therapy for age-related diseases. Trends Immunol (2009) 0.88
Basic biology and clinical impact of immunosenescence. Exp Gerontol (2002) 0.88
Expansion of peripheral CD8+ CD28- T cells in response to Epstein-Barr virus in patients with rheumatoid arthritis. J Rheumatol (2005) 0.87
Flow cytometric lymphocyte subset analysis using material from frozen whole blood. J Immunoassay Immunochem (2012) 0.86
Impact of aging on cancer immunity and immunotherapy. Cancer Immunol Immunother (2009) 0.85
Characterization of HLA class I altered phenotypes in a panel of human melanoma cell lines. Cancer Immunol Immunother (2007) 0.85
Nutritional status influences peripheral immune cell phenotypes in healthy men in rural Pakistan. Immun Ageing (2012) 0.85
Impact of age, sex and CMV-infection on peripheral T cell phenotypes: results from the Berlin BASE-II Study. Biogerontology (2015) 0.84
Relationship between anthropometric variables and nutrient intake in apparently healthy male elderly individuals: a study from Pakistan. Nutr J (2011) 0.84
Immunosenescence in vertebrates and invertebrates. Immun Ageing (2013) 0.83
Detection of Delta9-tetrahydrocannabinolic acid A in human urine and blood serum by LC-MS/MS. J Mass Spectrom (2007) 0.83
A novel B cell population revealed by a CD38/CD24 gating strategy: CD38(-)CD24 (-) B cells in centenarian offspring and elderly people. Age (Dordr) (2012) 0.83
A lack of telomeric non-reciprocal recombination (TENOR) may account for the premature proliferation blockade of Werner's syndrome fibroblasts. Biogerontology (2003) 0.83
Age-associated alterations in γδ T-cells are present predominantly in individuals infected with Cytomegalovirus. Immun Ageing (2013) 0.82
Impairment of the ABCA1 and SR-BI-mediated cholesterol efflux pathways and HDL anti-inflammatory activity in Alzheimer's disease. Mech Ageing Dev (2011) 0.82
Clusterin/Apolipoprotein J up-regulation after zinc exposure, replicative senescence or differentiation of human haematopoietic cells. Biogerontology (2006) 0.82
An investigation of DNA mismatch repair capacity under normal culture conditions and under conditions of supra-physiological challenge in human CD4+T cell clones from donors of different ages. Exp Gerontol (2005) 0.82
Mitochondrial DNA damage in lymphocytes: a role in immunosenescence? Exp Gerontol (2002) 0.82
Vaccination in the elderly. Microb Biotechnol (2011) 0.82
Presence of circulating Her2-reactive CD8 + T-cells is associated with lower frequencies of myeloid-derived suppressor cells and regulatory T cells, and better survival in older breast cancer patients. Breast Cancer Res (2015) 0.82
Prothymosin alpha immunoactive carboxyl-terminal peptide TKKQKTDEDD stimulates lymphocyte reactions, induces dendritic cell maturation and adopts a beta-sheet conformation in a sequence-specific manner. Mol Immunol (2008) 0.81
On the immunological theory of aging. Interdiscip Top Gerontol (2014) 0.81
Effect of culture at low oxygen tension on the expression of heat shock proteins in a panel of melanoma cell lines. PLoS One (2012) 0.81
International conference: progress in vaccination against cancer-2006 (PIVAC 6), Granada, Spain. Cancer Immunol Immunother (2007) 0.81
Mutual exclusivity analysis of genetic and epigenetic drivers in melanoma identifies a link between p14 ARF and RARβ signaling. Mol Cancer Res (2013) 0.81
SELDI-TOF-MS ProteinChip array profiling of T-cell clones propagated in long-term culture identifies human profilin-1 as a potential bio-marker of immunosenescence. Proteome Sci (2007) 0.81
Cytomegalovirus Infection Minimally Affects the Frequencies of B-Cell Phenotypes in Peripheral Blood of Younger and Older Adults. Gerontology (2016) 0.80