John L Telford

Author PubWeight™ 81.52‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial "pan-genome". Proc Natl Acad Sci U S A 2005 14.59
2 Complete genome sequence and comparative genomic analysis of an emerging human pathogen, serotype V Streptococcus agalactiae. Proc Natl Acad Sci U S A 2002 5.28
3 Genome analysis reveals pili in Group B Streptococcus. Science 2005 3.85
4 Identification of a universal Group B streptococcus vaccine by multiple genome screen. Science 2005 3.83
5 Group A Streptococcus produce pilus-like structures containing protective antigens and Lancefield T antigens. Proc Natl Acad Sci U S A 2005 3.59
6 Characterization and identification of vaccine candidate proteins through analysis of the group A Streptococcus surface proteome. Nat Biotechnol 2006 3.03
7 Identification of novel genomic islands coding for antigenic pilus-like structures in Streptococcus agalactiae. Mol Microbiol 2006 2.31
8 Streptococcus pyogenes pili promote pharyngeal cell adhesion and biofilm formation. Mol Microbiol 2007 2.01
9 The Helicobacter pylori vacuolating toxin inhibits T cell activation by two independent mechanisms. J Exp Med 2003 1.87
10 Preventing bacterial infections with pilus-based vaccines: the group B streptococcus paradigm. J Infect Dis 2009 1.64
11 Sortase A utilizes an ancillary protein anchor for efficient cell wall anchoring of pili in Streptococcus agalactiae. Infect Immun 2008 1.51
12 T helper type 1 lymphocytes drive inflammation in human atherosclerotic lesions. Proc Natl Acad Sci U S A 2003 1.37
13 Vaccinology in the genome era. J Clin Invest 2009 1.31
14 Mg(2+) signalling defines the group A streptococcal CsrRS (CovRS) regulon. Mol Microbiol 2007 1.31
15 Use of Lactococcus lactis expressing pili from group B Streptococcus as a broad-coverage vaccine against streptococcal disease. J Infect Dis 2006 1.19
16 Sequence variation in group A Streptococcus pili and association of pilus backbone types with lancefield T serotypes. J Infect Dis 2008 1.18
17 BibA: a novel immunogenic bacterial adhesin contributing to group B Streptococcus survival in human blood. Mol Microbiol 2007 1.18
18 Molecular mimicry between Helicobacter pylori antigens and H+, K+ --adenosine triphosphatase in human gastric autoimmunity. J Exp Med 2003 1.14
19 Multi high-throughput approach for highly selective identification of vaccine candidates: the Group A Streptococcus case. Mol Cell Proteomics 2012 1.13
20 Surfome analysis as a fast track to vaccine discovery: identification of a novel protective antigen for Group B Streptococcus hypervirulent strain COH1. Mol Cell Proteomics 2009 1.13
21 Structure-based approach to rationally design a chimeric protein for an effective vaccine against Group B Streptococcus infections. Proc Natl Acad Sci U S A 2011 1.09
22 Pilus backbone contributes to group B Streptococcus paracellular translocation through epithelial cells. J Infect Dis 2008 1.06
23 Immune subversion by Helicobacter pylori. Trends Immunol 2005 1.06
24 Capsular gene typing of Streptococcus agalactiae compared to serotyping by latex agglutination. J Clin Microbiol 2012 1.04
25 Scavenger receptor gp340 aggregates group A streptococci by binding pili. Mol Microbiol 2008 1.03
26 Helicobacter pylori toxin VacA is transferred to host cells via a novel contact-dependent mechanism. Cell Microbiol 2004 1.01
27 Relevance of pili in pathogenic streptococci pathogenesis and vaccine development. Future Microbiol 2010 0.95
28 Streptococcus pyogenes SpyCEP influences host-pathogen interactions during infection in a murine air pouch model. PLoS One 2012 0.92
29 Introduction of zwitterionic motifs into bacterial polysaccharides generates TLR2 agonists able to activate APCs. J Immunol 2007 0.91
30 Antigen receptor signaling: the Tuscan chronicles. Nat Immunol 2005 0.90
31 Regional variation among vacA alleles of Helicobacter pylori in China. J Clin Microbiol 2003 0.90
32 Toll-like receptor 2 dependent immunogenicity of glycoconjugate vaccines containing chemically derived zwitterionic polysaccharides. Proc Natl Acad Sci U S A 2009 0.89
33 Structure analysis and site-directed mutagenesis of defined key residues and motives for pilus-related sortase C1 in group B Streptococcus. FASEB J 2011 0.89
34 Group B Streptococcus crosses human epithelial cells by a paracellular route. J Infect Dis 2005 0.88
35 Evolution of functional polymorphism in the gene coding for the Helicobacter pylori cytotoxin. FEMS Microbiol Lett 2002 0.87
36 BibA induces opsonizing antibodies conferring in vivo protection against group B Streptococcus. J Infect Dis 2009 0.87
37 A Helicobacter pylori vacuolating toxin mutant that fails to oligomerize has a dominant negative phenotype. Infect Immun 2006 0.87
38 Transcriptional and proteomic profiles of group B Streptococcus type V reveal potential adherence proteins associated with high-level invasion. Infect Immun 2007 0.87
39 Simple sequence repeats and genome plasticity in Streptococcus agalactiae. J Bacteriol 2010 0.86
40 Functional characterization of a newly identified group B Streptococcus pullulanase eliciting antibodies able to prevent alpha-glucans degradation. PLoS One 2008 0.86
41 Human gastric glycosphingolipids recognized by Helicobacter pylori vacuolating cytotoxin VacA. Microbes Infect 2007 0.86
42 Structural basis for group B streptococcus pilus 1 sortases C regulation and specificity. PLoS One 2012 0.86
43 The cell-specific phenotype of the polymorphic vacA midregion is independent of the appearance of the cell surface receptor protein tyrosine phosphatase beta. Infect Immun 2006 0.84
44 Sortase A substrate specificity in GBS pilus 2a cell wall anchoring. PLoS One 2011 0.83
45 Defective Vav expression and impaired F-actin reorganization in a subset of patients with common variable immunodeficiency characterized by T-cell defects. Blood 2005 0.83
46 Genome-based approaches to vaccine development. J Mol Med (Berl) 2010 0.80
47 New insights into the role of the glutamic acid of the E-box motif in group B Streptococcus pilus 2a assembly. FASEB J 2012 0.79
48 Adaptive response of Group B streptococcus to high glucose conditions: new insights on the CovRS regulation network. PLoS One 2013 0.79
49 Understanding the molecular determinants driving the immunological specificity of the protective pilus 2a backbone protein of group B streptococcus. PLoS Comput Biol 2013 0.79
50 Group B Streptococcus pilus sortase regulation: a single mutation in the lid region induces pilin protein polymerization in vitro. FASEB J 2013 0.79
51 Exogenous sialic acid transport contributes to group B streptococcus infection of mucosal surfaces. J Infect Dis 2012 0.78
52 High-level intracellular expression of heterologous proteins in Brevibacillus choshinensis SP3 under the control of a xylose inducible promoter. Microb Cell Fact 2013 0.78
53 Corrigendum: Streptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline. Nat Commun 2015 0.75