Published in J Biol Chem on July 05, 2007
Protein disulfide isomerase acts as an injury response signal that enhances fibrin generation via tissue factor activation. J Clin Invest (2008) 2.39
Tissue factor activation: is disulfide bond switching a regulatory mechanism? Blood (2007) 2.37
A critical role for extracellular protein disulfide isomerase during thrombus formation in mice. J Clin Invest (2008) 2.26
Endothelium-derived but not platelet-derived protein disulfide isomerase is required for thrombus formation in vivo. Blood (2010) 1.43
Extracellular protein disulfide isomerase regulates coagulation on endothelial cells through modulation of phosphatidylserine exposure. Blood (2010) 1.29
Synergies of phosphatidylserine and protein disulfide isomerase in tissue factor activation. Thromb Haemost (2014) 1.29
P2X7 receptor signaling contributes to tissue factor-dependent thrombosis in mice. J Clin Invest (2011) 1.29
The endothelial protein C receptor supports tissue factor ternary coagulation initiation complex signaling through protease-activated receptors. J Biol Chem (2010) 1.24
Tissue factor regulation by epidermal growth factor receptor and epithelial-to-mesenchymal transitions: effect on tumor initiation and angiogenesis. Cancer Res (2008) 1.19
Rapid activation of monocyte tissue factor by antithymocyte globulin is dependent on complement and protein disulfide isomerase. Blood (2013) 1.07
Tissue factor encryption and decryption: facts and controversies. Thromb Res (2012) 0.96
Bovine protein disulfide isomerase-enhanced tissue factor coagulant function: is phospholipid contaminant in it the real culprit? Blood (2008) 0.96
Therapeutic implications of protein disulfide isomerase inhibition in thrombotic disease. Arterioscler Thromb Vasc Biol (2014) 0.94
Nox NADPH oxidases and the endoplasmic reticulum. Antioxid Redox Signal (2014) 0.94
Tissue factor, angiogenesis and tumour progression. Breast Cancer Res (2008) 0.93
Role of PDI in regulating tissue factor: FVIIa activity. Thromb Res (2010) 0.86
Caspase-1-mediated pathway promotes generation of thromboinflammatory microparticles. J Clin Invest (2015) 0.86
Tissue factor: mechanisms of decryption. Front Biosci (Elite Ed) (2012) 0.85
Post-streptococcal auto-antibodies inhibit protein disulfide isomerase and are associated with insulin resistance. PLoS One (2010) 0.84
Tissue factor mutated at the allosteric Cys186-Cys209 disulfide bond is severely impaired in decrypted procoagulant activity. Blood (2010) 0.84
Effect of protein disulfide isomerase chaperone activity inhibition on tissue factor activity. J Thromb Haemost (2010) 0.83
Tissue factor contributes to neutrophil CD11b expression in alpha-naphthylisothiocyanate-treated mice. Toxicol Appl Pharmacol (2010) 0.83
Extracellular Thiol Isomerases and Their Role in Thrombus Formation. Antioxid Redox Signal (2015) 0.82
Role of thiol pathways in TF procoagulant regulation. Thromb Res (2012) 0.82
Acid-denatured Green Fluorescent Protein (GFP) as model substrate to study the chaperone activity of protein disulfide isomerase. Int J Mol Sci (2011) 0.82
The tick-derived inhibitor Ixolaris prevents tissue factor signaling on tumor cells. J Thromb Haemost (2012) 0.81
S-nitrosothiols as selective antithrombotic agents - possible mechanisms. Br J Pharmacol (2010) 0.81
Novel therapies targeting endometriosis. Reprod Sci (2011) 0.81
Posttranslational modifications of tissue factor. Front Biosci (Elite Ed) (2012) 0.80
Cell surface thiol isomerases may explain the platelet-selective action of S-nitrosoglutathione. Nitric Oxide (2011) 0.80
Tracing the molecular pathogenesis of antiphospholipid syndrome. J Clin Invest (2008) 0.78
Decryption of tissue factor. Thromb Res (2012) 0.78
Protein-disulfide isomerase regulates the thyroid hormone receptor-mediated gene expression via redox factor-1 through thiol reduction-oxidation. J Biol Chem (2012) 0.78
Tissue factor structure and function. Scientifica (Cairo) (2012) 0.78
Vascular thiol isomerases. Blood (2016) 0.78
Platelets do not express the oxidized or reduced forms of tissue factor. Biochim Biophys Acta (2013) 0.77
Fas-induced apoptosis increases hepatocyte tissue factor procoagulant activity in vitro and in vivo. Toxicol Sci (2014) 0.76
Breast cancer phenotypes regulated by tissue factor-factor VII pathway: Possible therapeutic targets. World J Clin Oncol (2014) 0.76
Post-streptococcal antibodies are associated with metabolic syndrome in a population-based cohort. PLoS One (2011) 0.75
Protein disulfide isomerase inhibition blocks thrombin generation in humans by interfering with platelet factor V activation. JCI Insight (2017) 0.75
Structure-Function Relationship of the Interaction between Tissue Factor and Factor VIIa. Semin Thromb Hemost (2015) 0.75
Activation of endothelial cell protease activated receptor 1 by the protein C pathway. Science (2002) 5.35
Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation. Nature (2008) 3.14
Disulfide isomerization switches tissue factor from coagulation to cell signaling. Proc Natl Acad Sci U S A (2006) 2.65
Inhibition of tissue factor signaling suppresses tumor growth. Blood (2007) 2.16
Evidence for activation of tissue factor by an allosteric disulfide bond. Biochemistry (2006) 1.99
Regulation of angiogenesis by tissue factor cytoplasmic domain signaling. Nat Med (2004) 1.89
Regulation of tissue factor--mediated initiation of the coagulation cascade by cell surface grp78. Arterioscler Thromb Vasc Biol (2005) 1.82
Protease-activated receptor-1 signaling by activated protein C in cytokine-perturbed endothelial cells is distinct from thrombin signaling. J Biol Chem (2005) 1.81
Signaling of the tissue factor coagulation pathway in angiogenesis and cancer. Arterioscler Thromb Vasc Biol (2005) 1.78
Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis. Mol Cancer Res (2004) 1.68
Cross-talk of integrin alpha3beta1 and tissue factor in cell migration. Mol Biol Cell (2004) 1.57
Factor Xa binding to annexin 2 mediates signal transduction via protease-activated receptor 1. Circ Res (2008) 1.55
Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2-mediated heparin-binding EGF signaling in endothelial cells. Proc Natl Acad Sci U S A (2011) 1.52
Protease-activated receptor (PAR) 2, but not PAR1, signaling promotes the development of mammary adenocarcinoma in polyoma middle T mice. Cancer Res (2008) 1.50
Protease-activated receptor 2 signaling in inflammation. Semin Immunopathol (2011) 1.47
Protease-activated receptor 2-dependent phosphorylation of the tissue factor cytoplasmic domain. J Biol Chem (2004) 1.45
Science review: role of coagulation protease cascades in sepsis. Crit Care (2002) 1.37
Retracted Endogenous EPCR/aPC-PAR1 signaling prevents inflammation-induced vascular leakage and lethality. Blood (2009) 1.36
Role of protease activated receptor 1 and 2 signaling in hypoxia-induced angiogenesis. Arterioscler Thromb Vasc Biol (2007) 1.33
Tissue factor-protease-activated receptor 2 signaling promotes diet-induced obesity and adipose inflammation. Nat Med (2011) 1.31
Activation of cancer cell migration and invasion by ectopic synthesis of coagulation factor VII. Cancer Res (2006) 1.30
Tissue factor and PAR1 promote microbiota-induced intestinal vascular remodelling. Nature (2012) 1.29
Synergies of phosphatidylserine and protein disulfide isomerase in tissue factor activation. Thromb Haemost (2014) 1.29
P2X7 receptor signaling contributes to tissue factor-dependent thrombosis in mice. J Clin Invest (2011) 1.29
The endothelial protein C receptor supports tissue factor ternary coagulation initiation complex signaling through protease-activated receptors. J Biol Chem (2010) 1.24
Regulation of tissue factor-induced signaling by endogenous and recombinant tissue factor pathway inhibitor 1. Blood (2004) 1.24
Neutrophil activation by the tissue factor/Factor VIIa/PAR2 axis mediates fetal death in a mouse model of antiphospholipid syndrome. J Clin Invest (2008) 1.23
Inflammation, obesity, and thrombosis. Blood (2013) 1.21
Regulation of macrophage procoagulant responses by the tissue factor cytoplasmic domain in endotoxemia. Blood (2007) 1.18
Neutrophils release brakes of coagulation. Nat Med (2010) 1.16
Emerging insights in tissue factor-dependent signaling events. Semin Thromb Hemost (2006) 1.13
HIF2α-Sp1 interaction mediates a deacetylation-dependent FVII-gene activation under hypoxic conditions in ovarian cancer cells. Nucleic Acids Res (2012) 1.12
The tissue factor/factor VIIa/factor Xa complex: a model built by docking and site-directed mutagenesis. Proteins (2003) 1.11
Regulation of tissue factor cytoplasmic domain phosphorylation by palmitoylation. Blood (2003) 1.10
Tissue factor and PAR2 signaling in the tumor microenvironment. Arterioscler Thromb Vasc Biol (2009) 1.09
Cell surface proteomics identifies molecules functionally linked to tumor cell intravasation. J Biol Chem (2008) 1.09
Rapid activation of monocyte tissue factor by antithymocyte globulin is dependent on complement and protein disulfide isomerase. Blood (2013) 1.07
Plasmin-induced migration of endothelial cells. A potential target for the anti-angiogenic action of angiostatin. J Biol Chem (2002) 1.07
Endothelial protein C receptor function in murine and human breast cancer development. PLoS One (2013) 1.05
Activated protein C signals through the thrombin receptor PAR1 in endothelial cells. J Endotoxin Res (2003) 1.05
Evidence for tissue factor phosphorylation and its correlation with protease-activated receptor expression and the prognosis of primary breast cancer. Int J Cancer (2010) 1.05
Cooperation of tissue factor cytoplasmic domain and PAR2 signaling in breast cancer development. Blood (2010) 1.04
Immunochemical termination of self-tolerance. Proc Natl Acad Sci U S A (2008) 1.03
Alternatively spliced tissue factor promotes breast cancer growth in a β1 integrin-dependent manner. Proc Natl Acad Sci U S A (2013) 1.00
Plasmin-induced migration requires signaling through protease-activated receptor 1 and integrin alpha(9)beta(1). J Biol Chem (2004) 0.99
Tissue factor and glycoprotein C on herpes simplex virus type 1 are protease-activated receptor 2 cofactors that enhance infection. Blood (2012) 0.98
Role of PAR2 in murine pulmonary pseudomonal infection. Am J Physiol Lung Cell Mol Physiol (2007) 0.98
Orchestration of coagulation protease signaling by tissue factor. Trends Cardiovasc Med (2002) 0.96
Mechanistic studies of the immunochemical termination of self-tolerance with unnatural amino acids. Proc Natl Acad Sci U S A (2009) 0.94
Organ-specific protection against lipopolysaccharide-induced vascular leak is dependent on the endothelial protein C receptor. Arterioscler Thromb Vasc Biol (2013) 0.93
Hepatocyte nuclear factor-4-independent synthesis of coagulation factor VII in breast cancer cells and its inhibition by targeting selective histone acetyltransferases. Mol Cancer Res (2009) 0.93
Role of zymogenicity-determining residues of coagulation factor VII/VIIa in cofactor interaction and macromolecular substrate recognition. Biochemistry (2002) 0.93
Alternatively spliced tissue factor contributes to tumor spread and activation of coagulation in pancreatic ductal adenocarcinoma. Int J Cancer (2013) 0.91
Engineering of substrate selectivity for tissue factor.factor VIIa complex signaling through protease-activated receptor 2. J Biol Chem (2010) 0.90
Tissue factor and protease-activated receptor signaling in cancer. Semin Thromb Hemost (2008) 0.88
Complete abolishment of coagulant activity in monomeric disulfide-deficient tissue factor. Blood (2011) 0.87
Caspase-1-mediated pathway promotes generation of thromboinflammatory microparticles. J Clin Invest (2015) 0.86
Activated protein C in sepsis: the promise of nonanticoagulant activated protein C. Curr Opin Hematol (2008) 0.86
Nonproteolytic properties of murine alternatively spliced tissue factor: implications for integrin-mediated signaling in murine models. Mol Med (2012) 0.85
Thiol pathways in the regulation of tissue factor prothrombotic activity. Curr Opin Hematol (2011) 0.85
Tissue factor mutated at the allosteric Cys186-Cys209 disulfide bond is severely impaired in decrypted procoagulant activity. Blood (2010) 0.84
PAR1 signaling: more good than harm? Nat Med (2003) 0.83
Tissue factor proangiogenic signaling in cancer progression. Thromb Res (2012) 0.81
The tissue factor pathway mediates both activation of coagulation and coagulopathy after injury. J Trauma Acute Care Surg (2015) 0.81
Factor VII-activating protease promotes the proteolysis and inhibition of tissue factor pathway inhibitor. Arterioscler Thromb Vasc Biol (2011) 0.80
Infrared fluorescence for vascular barrier breach in vivo--a novel method for quantitation of albumin efflux. Thromb Haemost (2012) 0.80
Molecular dynamics simulations and functional characterization of the interactions of the PAR2 ectodomain with factor VIIa. Proteins (2009) 0.80
Immunomodulatory drugs increase endothelial tissue factor expression in vitro. Thromb Res (2010) 0.79
Tissue factor pathway inhibitor-2 (TFPI-2) recognizes the complement and kininogen binding protein gC1qR/p33 (gC1qR): implications for vascular inflammation. Thromb Haemost (2004) 0.78
Spectroscopic Characterization of Successive Phosphorylation of the Tissue Factor Cytoplasmic Region. Open Spectrosc J (2009) 0.77
Tissue factor associates with survival and regulates tumour progression in osteosarcoma. Thromb Haemost (2016) 0.76
Protease-activated receptor (Par)1 alters bioelectric properties of distal lung epithelia without compromising barrier function. Exp Lung Res (2009) 0.76
High-level secretion of tissue factor-rich extracellular vesicles from ovarian cancer cells mediated by filamin-A and protease-activated receptors. Thromb Haemost (2015) 0.76
Flow perturbation is linked to endothelial par signaling. Arterioscler Thromb Vasc Biol (2006) 0.75
Corrigendum: PAR1 signaling regulates the retention and recruitment of EPCR-expressing bone marrow hematopoietic stem cells. Nat Med (2016) 0.75
A hybrid fibronectin motif protein as an integrin targeting selective tumor vascular thrombogen. Mol Cancer Ther (2004) 0.75