Published in Proc Natl Acad Sci U S A on September 07, 2006
The pathogenesis of sepsis. Annu Rev Pathol (2011) 2.55
Protein disulfide isomerase acts as an injury response signal that enhances fibrin generation via tissue factor activation. J Clin Invest (2008) 2.39
Tissue factor activation: is disulfide bond switching a regulatory mechanism? Blood (2007) 2.37
A critical role for extracellular protein disulfide isomerase during thrombus formation in mice. J Clin Invest (2008) 2.26
Inhibition of tissue factor signaling suppresses tumor growth. Blood (2007) 2.16
Endothelial cell protein C receptor acts as a cellular receptor for factor VIIa on endothelium. J Biol Chem (2007) 2.01
In vitro and in vivo evidence for shear-induced activation of latent transforming growth factor-beta1. Blood (2008) 1.94
Cystine 186-cystine 209 disulfide bond is not essential for the procoagulant activity of tissue factor or for its de-encryption. Blood (2010) 1.92
Factor Xa binding to annexin 2 mediates signal transduction via protease-activated receptor 1. Circ Res (2008) 1.55
Protease-activated receptor (PAR) 2, but not PAR1, signaling promotes the development of mammary adenocarcinoma in polyoma middle T mice. Cancer Res (2008) 1.50
Redox signals in wound healing. Biochim Biophys Acta (2008) 1.49
Protease-activated receptor 2 signaling in inflammation. Semin Immunopathol (2011) 1.47
Protein disulfide isomerase inhibitors constitute a new class of antithrombotic agents. J Clin Invest (2012) 1.45
Endothelium-derived but not platelet-derived protein disulfide isomerase is required for thrombus formation in vivo. Blood (2010) 1.43
Tissue factor in coagulation: Which? Where? When? Arterioscler Thromb Vasc Biol (2009) 1.32
Tissue factor-protease-activated receptor 2 signaling promotes diet-induced obesity and adipose inflammation. Nat Med (2011) 1.31
Extracellular protein disulfide isomerase regulates coagulation on endothelial cells through modulation of phosphatidylserine exposure. Blood (2010) 1.29
Synergies of phosphatidylserine and protein disulfide isomerase in tissue factor activation. Thromb Haemost (2014) 1.29
P2X7 receptor signaling contributes to tissue factor-dependent thrombosis in mice. J Clin Invest (2011) 1.29
The endothelial protein C receptor supports tissue factor ternary coagulation initiation complex signaling through protease-activated receptors. J Biol Chem (2010) 1.24
Oxidative risk for atherothrombotic cardiovascular disease. Free Radic Biol Med (2009) 1.24
Proteases display biased agonism at protease-activated receptors: location matters! Mol Interv (2009) 1.24
Neutrophil activation by the tissue factor/Factor VIIa/PAR2 axis mediates fetal death in a mouse model of antiphospholipid syndrome. J Clin Invest (2008) 1.23
Inflammation, obesity, and thrombosis. Blood (2013) 1.21
Tissue factor and cell signalling in cancer progression and thrombosis. J Thromb Haemost (2011) 1.20
Search for allosteric disulfide bonds in NMR structures. BMC Struct Biol (2007) 1.15
T granules in human platelets function in TLR9 organization and signaling. J Cell Biol (2012) 1.13
Future innovations in anti-platelet therapies. Br J Pharmacol (2008) 1.13
Tissue factor in cancer progression and angiogenesis. Thromb Res (2010) 1.10
Tissue factor and PAR2 signaling in the tumor microenvironment. Arterioscler Thromb Vasc Biol (2009) 1.09
Rapid activation of monocyte tissue factor by antithymocyte globulin is dependent on complement and protein disulfide isomerase. Blood (2013) 1.07
Regulation of tissue factor coagulant activity on cell surfaces. J Thromb Haemost (2012) 0.99
Redox control of β2-glycoprotein I-von Willebrand factor interaction by thioredoxin-1. J Thromb Haemost (2010) 0.98
Tissue factor trafficking in fibroblasts: involvement of protease-activated receptor-mediated cell signaling. Blood (2007) 0.97
Bovine protein disulfide isomerase-enhanced tissue factor coagulant function: is phospholipid contaminant in it the real culprit? Blood (2008) 0.96
Tissue factor encryption and decryption: facts and controversies. Thromb Res (2012) 0.96
Targeting allosteric disulphide bonds in cancer. Nat Rev Cancer (2013) 0.96
Therapeutic modulation of coagulation and fibrinolysis in acute lung injury and the acute respiratory distress syndrome. Curr Pharm Biotechnol (2011) 0.96
Tissue factor and cancer. Thromb Res (2012) 0.95
Ero1alpha is expressed on blood platelets in association with protein-disulfide isomerase and contributes to redox-controlled remodeling of alphaIIbbeta3. J Biol Chem (2010) 0.94
Therapeutic implications of protein disulfide isomerase inhibition in thrombotic disease. Arterioscler Thromb Vasc Biol (2014) 0.94
Control of blood proteins by functional disulfide bonds. Blood (2014) 0.94
Nox NADPH oxidases and the endoplasmic reticulum. Antioxid Redox Signal (2014) 0.94
In vitro and in vivo evidence that thrombospondin-1 (TSP-1) contributes to stirring- and shear-dependent activation of platelet-derived TGF-beta1. PLoS One (2009) 0.93
Tissue factor, angiogenesis and tumour progression. Breast Cancer Res (2008) 0.93
Engineering of substrate selectivity for tissue factor.factor VIIa complex signaling through protease-activated receptor 2. J Biol Chem (2010) 0.90
Hepatocyte tissue factor activates the coagulation cascade in mice. Blood (2013) 0.90
Protein disulfide isomerase in thrombosis and vascular inflammation. J Thromb Haemost (2013) 0.89
Protein disulfide isomerase is required for platelet-derived growth factor-induced vascular smooth muscle cell migration, Nox1 NADPH oxidase expression, and RhoGTPase activation. J Biol Chem (2012) 0.89
The prothrombotic activity of cancer cells in the circulation. Blood Rev (2015) 0.88
Tissue factor and obesity, a two-way street. Nat Med (2011) 0.88
Plasma TF activity predicts cardiovascular mortality in patients with acute myocardial infarction. Thromb J (2009) 0.87
How it all starts: Initiation of the clotting cascade. Crit Rev Biochem Mol Biol (2015) 0.87
Plasmin enhances cell surface tissue factor activity in mesothelial and endothelial cells. J Thromb Haemost (2008) 0.86
Caspase-1-mediated pathway promotes generation of thromboinflammatory microparticles. J Clin Invest (2015) 0.86
Role of PDI in regulating tissue factor: FVIIa activity. Thromb Res (2010) 0.86
Tissue factor: mechanisms of decryption. Front Biosci (Elite Ed) (2012) 0.85
Thioredoxin and thioredoxin reductase control tissue factor activity by thiol redox-dependent mechanism. J Biol Chem (2012) 0.85
The C-terminal CGHC motif of protein disulfide isomerase supports thrombosis. J Clin Invest (2015) 0.85
Tissue factor mutated at the allosteric Cys186-Cys209 disulfide bond is severely impaired in decrypted procoagulant activity. Blood (2010) 0.84
The disulfide isomerase ERp57 is required for fibrin deposition in vivo. J Thromb Haemost (2014) 0.84
Effect of protein disulfide isomerase chaperone activity inhibition on tissue factor activity. J Thromb Haemost (2010) 0.83
Cryptic messages: is noncoagulant tissue factor reserved for cell signaling? Proc Natl Acad Sci U S A (2006) 0.83
Conformational changes in redox pairs of protein structures. Protein Sci (2009) 0.83
The Janus-faced role of external forces in mechanochemical disulfide bond cleavage. Nat Chem (2013) 0.83
Murine tissue factor coagulant activity is critically dependent on the presence of an intact allosteric disulfide. Haematologica (2012) 0.83
Tissue factor contributes to neutrophil CD11b expression in alpha-naphthylisothiocyanate-treated mice. Toxicol Appl Pharmacol (2010) 0.83
Extracellular Thiol Isomerases and Their Role in Thrombus Formation. Antioxid Redox Signal (2015) 0.82
Role of thiol pathways in TF procoagulant regulation. Thromb Res (2012) 0.82
The effect of tensile stress on the conformational free energy landscape of disulfide bonds. PLoS One (2014) 0.81
S-nitrosothiols as selective antithrombotic agents - possible mechanisms. Br J Pharmacol (2010) 0.81
Distinct contributions of complement factors to platelet activation and fibrin formation in venous thrombus development. Blood (2017) 0.81
The tick-derived inhibitor Ixolaris prevents tissue factor signaling on tumor cells. J Thromb Haemost (2012) 0.81
Role of tissue factor disulfides and lipid rafts in signaling. Thromb Res (2008) 0.81
Detection of tissue factor antigen and coagulation activity in coronary artery thrombi isolated from patients with ST-segment elevation acute myocardial infarction. PLoS One (2013) 0.81
Posttranslational modifications of tissue factor. Front Biosci (Elite Ed) (2012) 0.80
Analysis of tissue factor expression in various cell model systems: cryptic vs. active. J Thromb Haemost (2013) 0.80
Disulfide reduction abolishes tissue factor cofactor function. Biochim Biophys Acta (2013) 0.80
Role of the protein C receptor in cancer progression. Thromb Res (2014) 0.79
Site-specific S-nitrosylation of integrin α6 increases the extent of prostate cancer cell migration by enhancing integrin β1 association and weakening adherence to laminin-1. Biochemistry (2012) 0.79
The Eph tyrosine kinase receptors EphB2 and EphA2 are novel proteolytic substrates of tissue factor/coagulation factor VIIa. J Biol Chem (2014) 0.78
Decryption of tissue factor. Thromb Res (2012) 0.78
The branched-chain aminotransferase proteins: novel redox chaperones for protein disulfide isomerase--implications in Alzheimer's disease. Antioxid Redox Signal (2013) 0.78
Tissue factor structure and function. Scientifica (Cairo) (2012) 0.78
Vascular thiol isomerases. Blood (2016) 0.78
Protein-disulfide isomerase regulates the thyroid hormone receptor-mediated gene expression via redox factor-1 through thiol reduction-oxidation. J Biol Chem (2012) 0.78
Platelets do not express the oxidized or reduced forms of tissue factor. Biochim Biophys Acta (2013) 0.77
Platelet-targeting thiol reduction sensor detects thiol isomerase activity on activated platelets in mouse and human blood under flow. J Thromb Haemost (2016) 0.77
Tissue factor-dependent and -independent pathways of systemic coagulation activation in acute myeloid leukemia: a single-center cohort study. Exp Hematol Oncol (2015) 0.77
Tissue factor controversies. Thromb Res (2012) 0.77
Upregulation of the coagulation factor VII gene during glucose deprivation is mediated by activating transcription factor 4. PLoS One (2012) 0.76
Breast cancer phenotypes regulated by tissue factor-factor VII pathway: Possible therapeutic targets. World J Clin Oncol (2014) 0.76
Protease-activated receptor-2 signalling by tissue factor on dendritic cells suppresses antigen-specific CD4+ T-cell priming. Immunology (2013) 0.76
Evaluation of procoagulant tissue factor expression in canine hemangiosarcoma cell lines. Am J Vet Res (2017) 0.75
Targeting clotting proteins in cancer therapy - progress and challenges. Thromb Res (2016) 0.75
Protein disulfide isomerase inhibition blocks thrombin generation in humans by interfering with platelet factor V activation. JCI Insight (2017) 0.75
Revisiting the mechanistic basis of the French Paradox: Red wine inhibits the activity of protein disulfide isomerase in vitro. Thromb Res (2015) 0.75
One-Way Allosteric Communication between the Two Disulfide Bonds in Tissue Factor. Biophys J (2017) 0.75
Potential Coagulation Factor-Driven Pro-Inflammatory Responses in Ovarian Cancer Tissues Associated with Insufficient O₂ and Plasma Supply. Int J Mol Sci (2017) 0.75
Tissue factor/factor VIIa signalling promotes cytokine-induced beta cell death and impairs glucose-stimulated insulin secretion from human pancreatic islets. Diabetologia (2015) 0.75
Protein S-nitrosylation: a physiological signal for neuronal nitric oxide. Nat Cell Biol (2001) 9.82
Protease-activated receptors: contribution to physiology and disease. Physiol Rev (2004) 4.49
Disulfide bonds as switches for protein function. Trends Biochem Sci (2003) 3.14
Role of tissue factor in hemostasis, thrombosis, and vascular development. Arterioscler Thromb Vasc Biol (2004) 3.03
Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa. Proc Natl Acad Sci U S A (2000) 3.01
The regulation and pharmacology of endothelial nitric oxide synthase. Annu Rev Pharmacol Toxicol (2006) 2.68
Allosteric disulfide bonds. Biochemistry (2006) 2.32
Tissue factor encryption. Arterioscler Thromb Vasc Biol (2006) 2.12
Mechanistic coupling of protease signaling and initiation of coagulation by tissue factor. Proc Natl Acad Sci U S A (2001) 2.07
Regulation of angiogenesis by tissue factor cytoplasmic domain signaling. Nat Med (2004) 1.89
Tissue factor-factor VIIa-specific up-regulation of IL-8 expression in MDA-MB-231 cells is mediated by PAR-2 and results in increased cell migration. Blood (2004) 1.80
Signaling of the tissue factor coagulation pathway in angiogenesis and cancer. Arterioscler Thromb Vasc Biol (2005) 1.78
Relations between factor VIIa binding and expression of factor VIIa/tissue factor catalytic activity on cell surfaces. J Biol Chem (1992) 1.77
Inhibition of a reductive function of the plasma membrane by bacitracin and antibodies against protein disulfide-isomerase. Proc Natl Acad Sci U S A (1993) 1.71
Tissue factor-factor VIIa signaling. Arterioscler Thromb Vasc Biol (2004) 1.69
Enzymatically catalyzed disulfide exchange is required for platelet adhesion to collagen via integrin alpha2beta1. Blood (2003) 1.62
Cross-talk of integrin alpha3beta1 and tissue factor in cell migration. Mol Biol Cell (2004) 1.57
The integrity of the cysteine 186-cysteine 209 bond of the second disulfide loop of tissue factor is required for binding of factor VII. J Biol Chem (1991) 1.54
Mechanism of transfer of NO from extracellular S-nitrosothiols into the cytosol by cell-surface protein disulfide isomerase. Proc Natl Acad Sci U S A (2001) 1.51
Cell-surface protein disulfide isomerase catalyzes transnitrosation and regulates intracellular transfer of nitric oxide. J Clin Invest (1999) 1.49
Characterization of the S-denitrosation activity of protein disulfide isomerase. J Biol Chem (2004) 1.47
Protease-activated receptor 2-dependent phosphorylation of the tissue factor cytoplasmic domain. J Biol Chem (2004) 1.45
Protein disulfide isomerase and sulfhydryl-dependent pathways in platelet activation. Biochemistry (2001) 1.43
Science review: role of coagulation protease cascades in sepsis. Crit Care (2002) 1.37
Antibody mapping of tissue factor implicates two different exon-encoded regions in function. Biochem J (1991) 1.30
Recombinant soluble human tissue factor secreted by Saccharomyces cerevisiae and refolded from Escherichia coli inclusion bodies: glycosylation of mutants, activity and physical characterization. Biochem J (1995) 1.27
Regulation of tissue factor-induced signaling by endogenous and recombinant tissue factor pathway inhibitor 1. Blood (2004) 1.24
The mechanism of an inhibitory antibody on TF-initiated blood coagulation revealed by the crystal structures of human tissue factor, Fab 5G9 and TF.G9 complex. J Mol Biol (1998) 1.24
Cross-strand disulphides in cell entry proteins: poised to act. Bioessays (2004) 1.15
The tissue factor/factor VIIa/factor Xa complex: a model built by docking and site-directed mutagenesis. Proteins (2003) 1.11
Platelet cell-surface protein disulphide-isomerase mediated S-nitrosoglutathione consumption. Biochem J (2004) 1.05
Generation of angiostatin by reduction and proteolysis of plasmin. Catalysis by a plasmin reductase secreted by cultured cells. J Biol Chem (1997) 1.03
Enzyme destruction by a protease contaminant in bacitracin. Biochem Biophys Res Commun (2000) 0.98
The von Willebrand factor-reducing activity of thrombospondin-1 is located in the calcium-binding/C-terminal sequence and requires a free thiol at position 974. Blood (2002) 0.97
Redox modulation of integrin [correction of integin] alpha IIb beta 3 involves a novel allosteric regulation of its thiol isomerase activity. Biochemistry (2004) 0.92
Activation of endothelial cell protease activated receptor 1 by the protein C pathway. Science (2002) 5.35
Infliximab but not etanercept induces apoptosis in lamina propria T-lymphocytes from patients with Crohn's disease. Gastroenterology (2003) 3.41
Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation. Nature (2008) 3.14
Exenatide reduces infarct size and improves cardiac function in a porcine model of ischemia and reperfusion injury. J Am Coll Cardiol (2009) 2.94
Allosteric disulfide bonds. Biochemistry (2006) 2.32
Disulfide exchange in domain 2 of CD4 is required for entry of HIV-1. Nat Immunol (2002) 2.28
Inhibition of tissue factor signaling suppresses tumor growth. Blood (2007) 2.16
Epidemiology of cancer-associated venous thrombosis. Blood (2013) 2.00
Evidence for activation of tissue factor by an allosteric disulfide bond. Biochemistry (2006) 1.99
Carcinoma and stromal enzyme activity profiles associated with breast tumor growth in vivo. Proc Natl Acad Sci U S A (2004) 1.96
Regulation of angiogenesis by tissue factor cytoplasmic domain signaling. Nat Med (2004) 1.89
Thrombin generation and the pathogenesis of cancer. Semin Thromb Hemost (2006) 1.88
Prostanoids and prostanoid receptors in signal transduction. Int J Biochem Cell Biol (2004) 1.88
Protein profiles associated with survival in lung adenocarcinoma. Proc Natl Acad Sci U S A (2003) 1.86
Regulation of tissue factor--mediated initiation of the coagulation cascade by cell surface grp78. Arterioscler Thromb Vasc Biol (2005) 1.82
Protease-activated receptor-1 signaling by activated protein C in cytokine-perturbed endothelial cells is distinct from thrombin signaling. J Biol Chem (2005) 1.81
Arsenical-based cancer drugs. Cancer Treat Rev (2007) 1.78
Signaling of the tissue factor coagulation pathway in angiogenesis and cancer. Arterioscler Thromb Vasc Biol (2005) 1.78
Protease-activated receptors (PAR1 and PAR2) contribute to tumor cell motility and metastasis. Mol Cancer Res (2004) 1.68
Validity of bioluminescence measurements for noninvasive in vivo imaging of tumor load in small animals. Biotechniques (2007) 1.66
Tissue factor coagulant function is enhanced by protein-disulfide isomerase independent of oxidoreductase activity. J Biol Chem (2007) 1.65
The relationship between tissue factor and cancer progression: insights from bench and bedside. Blood (2011) 1.61
Cross-talk of integrin alpha3beta1 and tissue factor in cell migration. Mol Biol Cell (2004) 1.57
Factor Xa binding to annexin 2 mediates signal transduction via protease-activated receptor 1. Circ Res (2008) 1.55
Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2-mediated heparin-binding EGF signaling in endothelial cells. Proc Natl Acad Sci U S A (2011) 1.52
Protease-activated receptor (PAR) 2, but not PAR1, signaling promotes the development of mammary adenocarcinoma in polyoma middle T mice. Cancer Res (2008) 1.50
Protease-activated receptor 2 signaling in inflammation. Semin Immunopathol (2011) 1.47
Protease-activated receptor 2-dependent phosphorylation of the tissue factor cytoplasmic domain. J Biol Chem (2004) 1.45
Cutting edge: expression patterns of surface and soluble triggering receptor expressed on myeloid cells-1 in human endotoxemia. J Immunol (2004) 1.45
Protein-protein interaction between Fli-1 and GATA-1 mediates synergistic expression of megakaryocyte-specific genes through cooperative DNA binding. Mol Cell Biol (2003) 1.44
Science review: role of coagulation protease cascades in sepsis. Crit Care (2002) 1.37
Retracted Endogenous EPCR/aPC-PAR1 signaling prevents inflammation-induced vascular leakage and lethality. Blood (2009) 1.36
Mechanistic view of risk factors for venous thromboembolism. Arterioscler Thromb Vasc Biol (2012) 1.33
Role of protease activated receptor 1 and 2 signaling in hypoxia-induced angiogenesis. Arterioscler Thromb Vasc Biol (2007) 1.33
Tissue factor-protease-activated receptor 2 signaling promotes diet-induced obesity and adipose inflammation. Nat Med (2011) 1.31
Activation of cancer cell migration and invasion by ectopic synthesis of coagulation factor VII. Cancer Res (2006) 1.30
Tissue factor and PAR1 promote microbiota-induced intestinal vascular remodelling. Nature (2012) 1.29
Synergies of phosphatidylserine and protein disulfide isomerase in tissue factor activation. Thromb Haemost (2014) 1.29
P2X7 receptor signaling contributes to tissue factor-dependent thrombosis in mice. J Clin Invest (2011) 1.29
Molecular mechanism of violacein-mediated human leukemia cell death. Blood (2004) 1.27
Breaking the one antibody-one target axiom. Proc Natl Acad Sci U S A (2006) 1.26
The endothelial protein C receptor supports tissue factor ternary coagulation initiation complex signaling through protease-activated receptors. J Biol Chem (2010) 1.24
Regulation of tissue factor-induced signaling by endogenous and recombinant tissue factor pathway inhibitor 1. Blood (2004) 1.24
Neutrophil activation by the tissue factor/Factor VIIa/PAR2 axis mediates fetal death in a mouse model of antiphospholipid syndrome. J Clin Invest (2008) 1.23
Inflammation, obesity, and thrombosis. Blood (2013) 1.21
Post-translational control of protein function by disulfide bond cleavage. Antioxid Redox Signal (2013) 1.18
Regulation of macrophage procoagulant responses by the tissue factor cytoplasmic domain in endotoxemia. Blood (2007) 1.18
Neutrophils release brakes of coagulation. Nat Med (2010) 1.16
Cross-strand disulphides in cell entry proteins: poised to act. Bioessays (2004) 1.15
Search for allosteric disulfide bonds in NMR structures. BMC Struct Biol (2007) 1.15
Protease-activated receptor-2 regulates vascular endothelial growth factor expression in MDA-MB-231 cells via MAPK pathways. Biochem Biophys Res Commun (2006) 1.14
Emerging insights in tissue factor-dependent signaling events. Semin Thromb Hemost (2006) 1.13
HIF2α-Sp1 interaction mediates a deacetylation-dependent FVII-gene activation under hypoxic conditions in ovarian cancer cells. Nucleic Acids Res (2012) 1.12
Laser-induced endothelial cell activation supports fibrin formation. Blood (2010) 1.12
The tissue factor/factor VIIa/factor Xa complex: a model built by docking and site-directed mutagenesis. Proteins (2003) 1.11
Regulation of tissue factor cytoplasmic domain phosphorylation by palmitoylation. Blood (2003) 1.10
Congenital thrombotic thrombocytopenic purpura in association with a mutation in the second CUB domain of ADAMTS13. Blood (2003) 1.10
Cell surface proteomics identifies molecules functionally linked to tumor cell intravasation. J Biol Chem (2008) 1.09
Tissue factor and PAR2 signaling in the tumor microenvironment. Arterioscler Thromb Vasc Biol (2009) 1.09
Estrogen induces lung metastasis through a host compartment-specific response. Cancer Res (2006) 1.08
Rapid activation of monocyte tissue factor by antithymocyte globulin is dependent on complement and protein disulfide isomerase. Blood (2013) 1.07
Plasmin-induced migration of endothelial cells. A potential target for the anti-angiogenic action of angiostatin. J Biol Chem (2002) 1.07
Endothelial protein C receptor function in murine and human breast cancer development. PLoS One (2013) 1.05
Activated protein C signals through the thrombin receptor PAR1 in endothelial cells. J Endotoxin Res (2003) 1.05
Evidence for tissue factor phosphorylation and its correlation with protease-activated receptor expression and the prognosis of primary breast cancer. Int J Cancer (2010) 1.05
Role of thrombospondin-1 in control of von Willebrand factor multimer size in mice. J Biol Chem (2004) 1.05
Critical importance of the cell system when studying tissue factor de-encryption. Blood (2008) 1.04
Mitochondria as cancer drug targets. Trends Mol Med (2004) 1.04
Cooperation of tissue factor cytoplasmic domain and PAR2 signaling in breast cancer development. Blood (2010) 1.04
A peptide trivalent arsenical inhibits tumor angiogenesis by perturbing mitochondrial function in angiogenic endothelial cells. Cancer Cell (2003) 1.03
Experimental melanoma metastasis in lungs of mice with congenital coagulation disorders. J Cell Mol Med (2008) 1.03
Immunochemical termination of self-tolerance. Proc Natl Acad Sci U S A (2008) 1.03
Evidence for a domain-swapped CD4 dimer as the coreceptor for binding to class II MHC. J Immunol (2006) 1.01
Alternatively spliced tissue factor promotes breast cancer growth in a β1 integrin-dependent manner. Proc Natl Acad Sci U S A (2013) 1.00
Beta 2 glycoprotein I is a substrate of thiol oxidoreductases. Blood (2010) 0.99
Plasmin-induced migration requires signaling through protease-activated receptor 1 and integrin alpha(9)beta(1). J Biol Chem (2004) 0.99
Tissue factor and glycoprotein C on herpes simplex virus type 1 are protease-activated receptor 2 cofactors that enhance infection. Blood (2012) 0.98
Control of mature protein function by allosteric disulfide bonds. Antioxid Redox Signal (2010) 0.98
Role of PAR2 in murine pulmonary pseudomonal infection. Am J Physiol Lung Cell Mol Physiol (2007) 0.98
Direct effects of alcohol on hepatic fibrinolytic balance: implications for alcoholic liver disease. J Hepatol (2008) 0.98
The von Willebrand factor-reducing activity of thrombospondin-1 is located in the calcium-binding/C-terminal sequence and requires a free thiol at position 974. Blood (2002) 0.97
siRNA Down-regulation of the PATZ1 Gene in Human Glioma Cells Increases Their Sensitivity to Apoptotic Stimuli. Cancer Ther (2008) 0.96
Akt plays an important role in breast cancer cell chemotaxis to CXCL12. Breast Cancer Res Treat (2007) 0.96
Orchestration of coagulation protease signaling by tissue factor. Trends Cardiovasc Med (2002) 0.96