Published in J Biol Chem on December 25, 1991
Lessons from the genome sequence of Neurospora crassa: tracing the path from genomic blueprint to multicellular organism. Microbiol Mol Biol Rev (2004) 3.67
A Sec63p-BiP complex from yeast is required for protein translocation in a reconstituted proteoliposome. J Cell Biol (1993) 2.65
Identification of a 60-kilodalton stress-related protein, p60, which interacts with hsp90 and hsp70. Mol Cell Biol (1993) 2.36
Tumor rejection antigen gp96/grp94 is an ATPase: implications for protein folding and antigen presentation. EMBO J (1993) 2.25
Eukaryotic homologues of Escherichia coli dnaJ: a diverse protein family that functions with hsp70 stress proteins. Mol Biol Cell (1993) 2.15
The Escherichia coli heat shock gene htpY: mutational analysis, cloning, sequencing, and transcriptional regulation. J Bacteriol (1993) 2.03
Autoregulation of the Escherichia coli heat shock response by the DnaK and DnaJ heat shock proteins. Proc Natl Acad Sci U S A (1993) 1.93
Genome-wide analysis of the interaction between the endosymbiotic bacterium Wolbachia and its Drosophila host. BMC Genomics (2008) 1.84
Cloning, nucleotide sequence, and regulatory analysis of the Lactococcus lactis dnaJ gene. J Bacteriol (1993) 1.84
Molecular chaperones cooperate with PIM1 protease in the degradation of misfolded proteins in mitochondria. EMBO J (1994) 1.80
Stress response of yeast. Biochem J (1993) 1.79
Apoptosis in myocardial ischaemia and infarction. J Clin Pathol (2002) 1.59
Vascular heat shock protein expression in response to stress. Endocrine and autonomic regulation of this age-dependent response. J Clin Invest (1993) 1.34
HSP78 encodes a yeast mitochondrial heat shock protein in the Clp family of ATP-dependent proteases. Mol Cell Biol (1993) 1.33
Mitochondrial GrpE is present in a complex with hsp70 and preproteins in transit across membranes. Mol Cell Biol (1994) 1.27
Heat and osmotic stress responses of probiotic Lactobacillus rhamnosus HN001 (DR20) in relation to viability after drying. Appl Environ Microbiol (2003) 1.21
Response of Leishmania chagasi promastigotes to oxidant stress. Infect Immun (1994) 1.14
Toothpicks, serendipity and the emergence of the Escherichia coli DnaK (Hsp70) and GroEL (Hsp60) chaperone machines. Genetics (2006) 1.09
Glutathione S-transferase pi in an arsenic-resistant Chinese hamster ovary cell line. Biochem J (1992) 1.06
The essential Escherichia coli msgB gene, a multicopy suppressor of a temperature-sensitive allele of the heat shock gene grpE, is identical to dapE. J Bacteriol (1992) 1.05
The Hsp70 homologue Lhs1p is involved in a novel function of the yeast endoplasmic reticulum, refolding and stabilization of heat-denatured protein aggregates. J Cell Biol (1997) 1.05
Enhanced intestinal expression of heat shock protein 70 in patients with inflammatory bowel diseases. Dig Dis Sci (1999) 1.04
In vivo gene transfection with heat shock protein 70 enhances myocardial tolerance to ischemia-reperfusion injury in rat. J Clin Invest (1997) 1.03
Two genes abrogate the inhibition of murine hepatocarcinogenesis by ovarian hormones. Proc Natl Acad Sci U S A (1996) 1.01
Stress and immunological recognition in host-pathogen interactions. J Bacteriol (1992) 0.97
Fungal Hsp90: a biological transistor that tunes cellular outputs to thermal inputs. Nat Rev Microbiol (2012) 0.96
Heat shock proteins as carrier molecules: in vivo helper effect mediated by Escherichia coli GroEL and DnaK proteins requires cross-linking with antigen. Clin Exp Immunol (1994) 0.92
A protective Hsp70-TLR4 pathway in lethal oxidant lung injury. J Immunol (2013) 0.91
Evaluation for Hsp70 as a biomarker of effect of pollutants on the earthworm Lumbricus terrestris. Cell Stress Chaperones (2001) 0.91
Synergistic promotion of breast cancer cells death by targeting molecular chaperone GRP78 and heat shock protein 70. J Cell Mol Med (2010) 0.91
J domain co-chaperone specificity defines the role of BiP during protein translocation. J Biol Chem (2010) 0.90
ClpB in a cyanobacterium: predicted structure, phylogenetic relationships, and regulation by light and temperature. J Bacteriol (1998) 0.89
Proteomics analysis of Lactobacillus casei Zhang, a new probiotic bacterium isolated from traditional home-made koumiss in Inner Mongolia of China. Mol Cell Proteomics (2009) 0.88
Oxalate exposure provokes HSP 70 response in LLC-PK1 cells, a line of renal epithelial cells: protective role of HSP 70 against oxalate toxicity. Urol Res (2008) 0.88
Viability of rep recA mutants depends on their capacity to cope with spontaneous oxidative damage and on the DnaK chaperone protein. J Bacteriol (2001) 0.87
The 66 kDa component of yeast SFI, stimulatory factor I, is hsp60. Nucleic Acids Res (1992) 0.85
Autophosphorylation of the pea mitochondrial heat-shock protein homolog. Plant Physiol (1992) 0.85
Glutamine induces heat-shock protein and protects against Escherichia coli lipopolysaccharide-induced vascular hyporeactivity in rats. Crit Care (2007) 0.84
dnaJ in Archaea. Nucleic Acids Res (1993) 0.83
Expression of a malarial Hsp70 improves defects in chaperone-dependent activities in ssa1 mutant yeast. PLoS One (2011) 0.82
FTSJ2, a heat shock-inducible mitochondrial protein, suppresses cell invasion and migration. PLoS One (2014) 0.81
An ATP- and hsc70-dependent oligomerization of nascent heat-shock factor (HSF) polypeptide suggests that HSF itself could be a "sensor" for the cellular stress response. Protein Sci (1993) 0.81
Year in review 2007: Critical Care--multiple organ failure and sepsis. Crit Care (2008) 0.80
Immunogenicity of the meningococcal stress protein MSP63 during natural infection. Clin Exp Immunol (1993) 0.79
Transposon mutagenesis of probiotic Lactobacillus casei identifies asnH, an asparagine synthetase gene involved in its immune-activating capacity. PLoS One (2014) 0.75
NaCl stress impact on the key enzymes in glycolysis from Lactobacillus bulgaricus during freeze-drying. Braz J Microbiol (2015) 0.75
Enhanced intracellular heat shock protein 70 expression of leukocytes and serum interleukins release: comparison of on-pump and off-pump coronary artery surgery. World J Surg (2010) 0.75
Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase. Science (1999) 6.38
Escherichia coli DnaJ and GrpE heat shock proteins jointly stimulate ATPase activity of DnaK. Proc Natl Acad Sci U S A (1991) 5.96
The dnaK protein modulates the heat-shock response of Escherichia coli. Cell (1983) 5.53
The groES and groEL heat shock gene products of Escherichia coli are essential for bacterial growth at all temperatures. J Bacteriol (1989) 4.81
Identification, characterization, and mapping of the Escherichia coli htrA gene, whose product is essential for bacterial growth only at elevated temperatures. J Bacteriol (1989) 4.71
Sequence analysis and regulation of the htrA gene of Escherichia coli: a sigma 32-independent mechanism of heat-inducible transcription. Nucleic Acids Res (1988) 4.19
Interactions of bacteriophage and host macromolecules in the growth of bacteriophage lambda. Microbiol Rev (1984) 4.17
The dnaK protein of Escherichia coli possesses an ATPase and autophosphorylating activity and is essential in an in vitro DNA replication system. Proc Natl Acad Sci U S A (1983) 3.96
Initiation of lambda DNA replication with purified host- and bacteriophage-encoded proteins: the role of the dnaK, dnaJ and grpE heat shock proteins. EMBO J (1989) 3.58
A molecular chaperone, ClpA, functions like DnaK and DnaJ. Proc Natl Acad Sci U S A (1994) 3.51
The E. coli dnaK gene product, the hsp70 homolog, can reactivate heat-inactivated RNA polymerase in an ATP hydrolysis-dependent manner. Cell (1990) 3.51
Modulation of the Escherichia coli sigmaE (RpoE) heat-shock transcription-factor activity by the RseA, RseB and RseC proteins. Mol Microbiol (1997) 3.51
The rpoE gene encoding the sigma E (sigma 24) heat shock sigma factor of Escherichia coli. EMBO J (1995) 3.29
SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex. Mol Cell (1999) 3.19
The HtrA (DegP) protein, essential for Escherichia coli survival at high temperatures, is an endopeptidase. J Bacteriol (1990) 3.14
The nucleotide sequence of the Escherichia coli K12 dnaJ+ gene. A gene that encodes a heat shock protein. J Biol Chem (1986) 3.04
Identification of a second Escherichia coli groE gene whose product is necessary for bacteriophage morphogenesis. Proc Natl Acad Sci U S A (1981) 2.94
Purification and properties of the Escherichia coli dnaK replication protein. J Biol Chem (1984) 2.92
Three pure chaperone proteins of Escherichia coli--SecB, trigger factor and GroEL--form soluble complexes with precursor proteins in vitro. EMBO J (1989) 2.89
The NH2-terminal 108 amino acids of the Escherichia coli DnaJ protein stimulate the ATPase activity of DnaK and are sufficient for lambda replication. J Biol Chem (1994) 2.85
Purification and properties of the dnaJ replication protein of Escherichia coli. J Biol Chem (1985) 2.84
Isolation and characterization of ClpX, a new ATP-dependent specificity component of the Clp protease of Escherichia coli. J Biol Chem (1993) 2.83
Modulation of stability of the Escherichia coli heat shock regulatory factor sigma. J Bacteriol (1989) 2.80
Identification and characterization of the Escherichia coli gene dsbB, whose product is involved in the formation of disulfide bonds in vivo. Proc Natl Acad Sci U S A (1993) 2.70
The ClpX heat-shock protein of Escherichia coli, the ATP-dependent substrate specificity component of the ClpP-ClpX protease, is a novel molecular chaperone. EMBO J (1995) 2.63
The DnaK chaperone modulates the heat shock response of Escherichia coli by binding to the sigma 32 transcription factor. Proc Natl Acad Sci U S A (1992) 2.63
The universally conserved GroE (Hsp60) chaperonins. Annu Rev Microbiol (1991) 2.56
Escherichia coli grpE gene codes for heat shock protein B25.3, essential for both lambda DNA replication at all temperatures and host growth at high temperature. J Bacteriol (1986) 2.55
Function of Escherichia coli MsbA, an essential ABC family transporter, in lipid A and phospholipid biosynthesis. J Biol Chem (1998) 2.53
The Escherichia coli DnaK chaperone, the 70-kDa heat shock protein eukaryotic equivalent, changes conformation upon ATP hydrolysis, thus triggering its dissociation from a bound target protein. J Biol Chem (1991) 2.47
Role of the Escherichia coli DnaK and DnaJ heat shock proteins in the initiation of bacteriophage lambda DNA replication. Proc Natl Acad Sci U S A (1988) 2.42
The grpE protein of Escherichia coli. Purification and properties. J Biol Chem (1987) 2.40
The Escherichia coli dsbC (xprA) gene encodes a periplasmic protein involved in disulfide bond formation. EMBO J (1994) 2.34
Polypeptide flux through bacterial Hsp70: DnaK cooperates with trigger factor in chaperoning nascent chains. Cell (1999) 2.33
The B66.0 protein of Escherichia coli is the product of the dnaK+ gene. J Bacteriol (1982) 2.19
Suppression of the Escherichia coli dnaA46 mutation by amplification of the groES and groEL genes. Mol Gen Genet (1986) 2.18
The heat-shock-regulated grpE gene of Escherichia coli is required for bacterial growth at all temperatures but is dispensable in certain mutant backgrounds. J Bacteriol (1989) 2.15
Heat shock regulatory gene rpoH mRNA level increases after heat shock in Escherichia coli. J Bacteriol (1986) 2.04
The Escherichia coli heat shock gene htpY: mutational analysis, cloning, sequencing, and transcriptional regulation. J Bacteriol (1993) 2.03
Isolation and characterization of the Escherichia coli htrB gene, whose product is essential for bacterial viability above 33 degrees C in rich media. J Bacteriol (1991) 2.02
NMR structure determination of the Escherichia coli DnaJ molecular chaperone: secondary structure and backbone fold of the N-terminal region (residues 2-108) containing the highly conserved J domain. Proc Natl Acad Sci U S A (1994) 2.00
Purification and properties of the groES morphogenetic protein of Escherichia coli. J Biol Chem (1986) 2.00
Identification and characterization of HsIV HsIU (ClpQ ClpY) proteins involved in overall proteolysis of misfolded proteins in Escherichia coli. EMBO J (1996) 1.98
The T/t common exon of simian virus 40, JC, and BK polyomavirus T antigens can functionally replace the J-domain of the Escherichia coli DnaJ molecular chaperone. Proc Natl Acad Sci U S A (1997) 1.95
Autoregulation of the Escherichia coli heat shock response by the DnaK and DnaJ heat shock proteins. Proc Natl Acad Sci U S A (1993) 1.93
Sequence analysis and transcriptional regulation of the Escherichia coli grpE gene, encoding a heat shock protein. Nucleic Acids Res (1988) 1.87
NMR structure of the J-domain and the Gly/Phe-rich region of the Escherichia coli DnaJ chaperone. J Mol Biol (1996) 1.85
Isolation and characterization of the Escherichia coli msbB gene, a multicopy suppressor of null mutations in the high-temperature requirement gene htrB. J Bacteriol (1992) 1.81
A new Escherichia coli heat shock gene, htrC, whose product is essential for viability only at high temperatures. J Bacteriol (1990) 1.76
Characterization of a functionally important mobile domain of GroES. Nature (1993) 1.74
Escherichia coli DnaK and GrpE heat shock proteins interact both in vivo and in vitro. J Bacteriol (1989) 1.74
The essential Escherichia coli msbA gene, a multicopy suppressor of null mutations in the htrB gene, is related to the universally conserved family of ATP-dependent translocators. Mol Microbiol (1993) 1.73
Structure-function analysis of the zinc finger region of the DnaJ molecular chaperone. J Biol Chem (1996) 1.72
The conserved G/F motif of the DnaJ chaperone is necessary for the activation of the substrate binding properties of the DnaK chaperone. J Biol Chem (1995) 1.71
Isolation and characterization of dnaJ null mutants of Escherichia coli. J Bacteriol (1990) 1.70
A mitochondrial homolog of bacterial GrpE interacts with mitochondrial hsp70 and is essential for viability. EMBO J (1994) 1.60
Initiation of DNA replication on single-stranded DNA templates catalyzed by purified replication proteins of bacteriophage lambda and Escherichia coli. Proc Natl Acad Sci U S A (1985) 1.59
Physical interactions between bacteriophage and Escherichia coli proteins required for initiation of lambda DNA replication. J Biol Chem (1990) 1.59
Both the Escherichia coli chaperone systems, GroEL/GroES and DnaK/DnaJ/GrpE, can reactivate heat-treated RNA polymerase. Different mechanisms for the same activity. J Biol Chem (1993) 1.58
Role of Escherichia coli heat shock proteins DnaK and HtpG (C62.5) in response to nutritional deprivation. J Bacteriol (1990) 1.57
Recognition, targeting, and hydrolysis of the lambda O replication protein by the ClpP/ClpX protease. J Biol Chem (1999) 1.55
Identification and transcriptional analysis of the Escherichia coli htrE operon which is homologous to pap and related pilin operons. J Bacteriol (1993) 1.52
The Escherichia coli heat shock proteins GroEL and GroES modulate the folding of the beta-lactamase precursor. EMBO J (1990) 1.50
Mitochondrial Hsp70 Ssc1: role in protein folding. J Biol Chem (2000) 1.50
Functional domains of the Escherichia coli dnaK heat shock protein as revealed by mutational analysis. J Biol Chem (1989) 1.49
Escherichia coli DnaK protein possesses a 5'-nucleotidase activity that is inhibited by AppppA. J Bacteriol (1986) 1.46
Mutational analysis and properties of the msbA gene of Escherichia coli, coding for an essential ABC family transporter. Mol Microbiol (1996) 1.44
The htrM gene, whose product is essential for Escherichia coli viability only at elevated temperatures, is identical to the rfaD gene. Nucleic Acids Res (1991) 1.43
On the mechanism of FtsH-dependent degradation of the sigma 32 transcriptional regulator of Escherichia coli and the role of the Dnak chaperone machine. Mol Microbiol (1999) 1.42
Co-chaperones Bag-1, Hop and Hsp40 regulate Hsc70 and Hsp90 interactions with wild-type or mutant p53. EMBO J (2001) 1.42
Divergent effects of ATP on the binding of the DnaK and DnaJ chaperones to each other, or to their various native and denatured protein substrates. J Biol Chem (1995) 1.41
The Clp ATPases define a novel class of molecular chaperones. Mol Microbiol (1996) 1.40