Published in J Biol Chem on December 15, 1989
Cloning, sequencing, and molecular analysis of the dnaK locus from Bacillus subtilis. J Bacteriol (1992) 3.62
Involvement of the chaperonin dnaK in the rapid degradation of a mutant protein in Escherichia coli. EMBO J (1992) 2.29
DnaK as a thermometer: threonine-199 is site of autophosphorylation and is critical for ATPase activity. Proc Natl Acad Sci U S A (1991) 2.20
A small heat shock protein cooperates with heat shock protein 70 systems to reactivate a heat-denatured protein. Plant Physiol (2000) 2.08
Molecular characterization of the dnaK gene region of Clostridium acetobutylicum, including grpE, dnaJ, and a new heat shock gene. J Bacteriol (1992) 2.06
Partial loss of function mutations in DnaK, the Escherichia coli homologue of the 70-kDa heat shock proteins, affect highly conserved amino acids implicated in ATP binding and hydrolysis. Proc Natl Acad Sci U S A (1992) 1.31
Mutant DnaK chaperones cause ribosome assembly defects in Escherichia coli. Proc Natl Acad Sci U S A (1993) 1.30
DnaK mutants defective in ATPase activity are defective in negative regulation of the heat shock response: expression of mutant DnaK proteins results in filamentation. J Bacteriol (1994) 1.24
Inorganic cation transport and energy transduction in Enterococcus hirae and other streptococci. Microbiol Mol Biol Rev (1998) 1.13
Homology modelling of integrin EF-hands. Evidence for widespread use of a conserved cation-binding site. Biochem J (1992) 1.08
Characteristics of an Hsp70 homolog localized in higher plant chloroplasts that is similar to DnaK, the Hsp70 of prokaryotes. Plant Physiol (1993) 0.98
Induced levels of heat shock proteins in a dnaK mutant of Lactococcus lactis. J Bacteriol (1998) 0.97
A single base change in the acceptor stem of tRNA(3Leu) confers resistance upon Escherichia coli to the calmodulin inhibitor, 48/80. EMBO J (1991) 0.94
Cloning, characterization, and functional expression in Escherichia coli of chaperonin (groESL) genes from the phototrophic sulfur bacterium Chromatium vinosum. J Bacteriol (1993) 0.94
Identification of a 71-kilodalton surface-associated Hsp70 homologue in Coxiella burnetii. Infect Immun (1998) 0.93
The variable C-terminal region of the Mycobacterium leprae 70-kilodalton heat shock protein is the target for humoral immune responses. Infect Immun (1992) 0.92
Monoclonal antibody recognition and function of a DnaK (HSP70) epitope found in gram-negative bacteria. J Bacteriol (1993) 0.91
Mutations which alter the kinetics of calcium transport alter the regulation of competence in Streptococcus pneumoniae. J Bacteriol (1994) 0.89
Segmental isotopic labeling of the Hsp70 molecular chaperone DnaK using expressed protein ligation. Biopolymers (2010) 0.88
Improvement of multiple-stress tolerance and lactic acid production in Lactococcus lactis NZ9000 under conditions of thermal stress by heterologous expression of Escherichia coli DnaK. Appl Environ Microbiol (2010) 0.87
High-level expression of soluble rat hsc70 in Escherichia coli: purification and characterization of the cloned enzyme. Biochem J (1993) 0.83
Cloning and expression in Escherichia coli of the dnaK gene of Zymomonas mobilis. J Bacteriol (1993) 0.82
DNA sequence analysis of the dnaK gene of Escherichia coli B and of two dnaK genes carrying the temperature-sensitive mutations dnaK7(Ts) and dnaK756(Ts). J Bacteriol (1992) 0.79
Histidine 89 is an essential residue for Hsp70 in the phosphate transfer reaction. Cell Stress Chaperones (2006) 0.77
Heat shock proteins and regulatory T cells. Autoimmune Dis (2013) 0.77
Reactivation of Aggregated Proteins by the ClpB/DnaK Bi-Chaperone System. Curr Protoc Protein Sci (2016) 0.75
ATPase activity and molecular chaperone function of the stress70 proteins. Plant Physiol (1996) 0.75
Escherichia coli DnaJ and GrpE heat shock proteins jointly stimulate ATPase activity of DnaK. Proc Natl Acad Sci U S A (1991) 5.96
The dnaK protein modulates the heat-shock response of Escherichia coli. Cell (1983) 5.53
The groES and groEL heat shock gene products of Escherichia coli are essential for bacterial growth at all temperatures. J Bacteriol (1989) 4.81
Identification, characterization, and mapping of the Escherichia coli htrA gene, whose product is essential for bacterial growth only at elevated temperatures. J Bacteriol (1989) 4.71
Sequence analysis and regulation of the htrA gene of Escherichia coli: a sigma 32-independent mechanism of heat-inducible transcription. Nucleic Acids Res (1988) 4.19
Interactions of bacteriophage and host macromolecules in the growth of bacteriophage lambda. Microbiol Rev (1984) 4.17
The dnaK protein of Escherichia coli possesses an ATPase and autophosphorylating activity and is essential in an in vitro DNA replication system. Proc Natl Acad Sci U S A (1983) 3.96
Initiation of lambda DNA replication with purified host- and bacteriophage-encoded proteins: the role of the dnaK, dnaJ and grpE heat shock proteins. EMBO J (1989) 3.58
The E. coli dnaK gene product, the hsp70 homolog, can reactivate heat-inactivated RNA polymerase in an ATP hydrolysis-dependent manner. Cell (1990) 3.51
Modulation of the Escherichia coli sigmaE (RpoE) heat-shock transcription-factor activity by the RseA, RseB and RseC proteins. Mol Microbiol (1997) 3.51
The rpoE gene encoding the sigma E (sigma 24) heat shock sigma factor of Escherichia coli. EMBO J (1995) 3.29
The HtrA (DegP) protein, essential for Escherichia coli survival at high temperatures, is an endopeptidase. J Bacteriol (1990) 3.14
The nucleotide sequence of the Escherichia coli K12 dnaJ+ gene. A gene that encodes a heat shock protein. J Biol Chem (1986) 3.04
Identification of a second Escherichia coli groE gene whose product is necessary for bacteriophage morphogenesis. Proc Natl Acad Sci U S A (1981) 2.94
Purification and properties of the Escherichia coli dnaK replication protein. J Biol Chem (1984) 2.92
Three pure chaperone proteins of Escherichia coli--SecB, trigger factor and GroEL--form soluble complexes with precursor proteins in vitro. EMBO J (1989) 2.89
The NH2-terminal 108 amino acids of the Escherichia coli DnaJ protein stimulate the ATPase activity of DnaK and are sufficient for lambda replication. J Biol Chem (1994) 2.85
Purification and properties of the dnaJ replication protein of Escherichia coli. J Biol Chem (1985) 2.84
Isolation and characterization of ClpX, a new ATP-dependent specificity component of the Clp protease of Escherichia coli. J Biol Chem (1993) 2.83
Modulation of stability of the Escherichia coli heat shock regulatory factor sigma. J Bacteriol (1989) 2.80
Identification and characterization of the Escherichia coli gene dsbB, whose product is involved in the formation of disulfide bonds in vivo. Proc Natl Acad Sci U S A (1993) 2.70
The DnaK chaperone modulates the heat shock response of Escherichia coli by binding to the sigma 32 transcription factor. Proc Natl Acad Sci U S A (1992) 2.63
The ClpX heat-shock protein of Escherichia coli, the ATP-dependent substrate specificity component of the ClpP-ClpX protease, is a novel molecular chaperone. EMBO J (1995) 2.63
The universally conserved GroE (Hsp60) chaperonins. Annu Rev Microbiol (1991) 2.56
Escherichia coli grpE gene codes for heat shock protein B25.3, essential for both lambda DNA replication at all temperatures and host growth at high temperature. J Bacteriol (1986) 2.55
Function of Escherichia coli MsbA, an essential ABC family transporter, in lipid A and phospholipid biosynthesis. J Biol Chem (1998) 2.53
The Escherichia coli DnaK chaperone, the 70-kDa heat shock protein eukaryotic equivalent, changes conformation upon ATP hydrolysis, thus triggering its dissociation from a bound target protein. J Biol Chem (1991) 2.47
Role of the Escherichia coli DnaK and DnaJ heat shock proteins in the initiation of bacteriophage lambda DNA replication. Proc Natl Acad Sci U S A (1988) 2.42
The grpE protein of Escherichia coli. Purification and properties. J Biol Chem (1987) 2.40
The Escherichia coli dsbC (xprA) gene encodes a periplasmic protein involved in disulfide bond formation. EMBO J (1994) 2.34
Polypeptide flux through bacterial Hsp70: DnaK cooperates with trigger factor in chaperoning nascent chains. Cell (1999) 2.33
The B66.0 protein of Escherichia coli is the product of the dnaK+ gene. J Bacteriol (1982) 2.19
Suppression of the Escherichia coli dnaA46 mutation by amplification of the groES and groEL genes. Mol Gen Genet (1986) 2.18
The heat-shock-regulated grpE gene of Escherichia coli is required for bacterial growth at all temperatures but is dispensable in certain mutant backgrounds. J Bacteriol (1989) 2.15
Heat shock regulatory gene rpoH mRNA level increases after heat shock in Escherichia coli. J Bacteriol (1986) 2.04
The Escherichia coli heat shock gene htpY: mutational analysis, cloning, sequencing, and transcriptional regulation. J Bacteriol (1993) 2.03
Isolation and characterization of the Escherichia coli htrB gene, whose product is essential for bacterial viability above 33 degrees C in rich media. J Bacteriol (1991) 2.02
NMR structure determination of the Escherichia coli DnaJ molecular chaperone: secondary structure and backbone fold of the N-terminal region (residues 2-108) containing the highly conserved J domain. Proc Natl Acad Sci U S A (1994) 2.00
Purification and properties of the groES morphogenetic protein of Escherichia coli. J Biol Chem (1986) 2.00
Identification and characterization of HsIV HsIU (ClpQ ClpY) proteins involved in overall proteolysis of misfolded proteins in Escherichia coli. EMBO J (1996) 1.98
Biological role and regulation of the universally conserved heat shock proteins. J Biol Chem (1991) 1.97
The T/t common exon of simian virus 40, JC, and BK polyomavirus T antigens can functionally replace the J-domain of the Escherichia coli DnaJ molecular chaperone. Proc Natl Acad Sci U S A (1997) 1.95
Autoregulation of the Escherichia coli heat shock response by the DnaK and DnaJ heat shock proteins. Proc Natl Acad Sci U S A (1993) 1.93
Sequence analysis and transcriptional regulation of the Escherichia coli grpE gene, encoding a heat shock protein. Nucleic Acids Res (1988) 1.87
NMR structure of the J-domain and the Gly/Phe-rich region of the Escherichia coli DnaJ chaperone. J Mol Biol (1996) 1.85
Isolation and characterization of the Escherichia coli msbB gene, a multicopy suppressor of null mutations in the high-temperature requirement gene htrB. J Bacteriol (1992) 1.81
A new Escherichia coli heat shock gene, htrC, whose product is essential for viability only at high temperatures. J Bacteriol (1990) 1.76
Characterization of a functionally important mobile domain of GroES. Nature (1993) 1.74
Escherichia coli DnaK and GrpE heat shock proteins interact both in vivo and in vitro. J Bacteriol (1989) 1.74
The essential Escherichia coli msbA gene, a multicopy suppressor of null mutations in the htrB gene, is related to the universally conserved family of ATP-dependent translocators. Mol Microbiol (1993) 1.73
Structure-function analysis of the zinc finger region of the DnaJ molecular chaperone. J Biol Chem (1996) 1.72
The conserved G/F motif of the DnaJ chaperone is necessary for the activation of the substrate binding properties of the DnaK chaperone. J Biol Chem (1995) 1.71
Isolation and characterization of dnaJ null mutants of Escherichia coli. J Bacteriol (1990) 1.70
A mitochondrial homolog of bacterial GrpE interacts with mitochondrial hsp70 and is essential for viability. EMBO J (1994) 1.60
Initiation of DNA replication on single-stranded DNA templates catalyzed by purified replication proteins of bacteriophage lambda and Escherichia coli. Proc Natl Acad Sci U S A (1985) 1.59
Physical interactions between bacteriophage and Escherichia coli proteins required for initiation of lambda DNA replication. J Biol Chem (1990) 1.59
Both the Escherichia coli chaperone systems, GroEL/GroES and DnaK/DnaJ/GrpE, can reactivate heat-treated RNA polymerase. Different mechanisms for the same activity. J Biol Chem (1993) 1.58
Role of Escherichia coli heat shock proteins DnaK and HtpG (C62.5) in response to nutritional deprivation. J Bacteriol (1990) 1.57
Recognition, targeting, and hydrolysis of the lambda O replication protein by the ClpP/ClpX protease. J Biol Chem (1999) 1.55
Identification and transcriptional analysis of the Escherichia coli htrE operon which is homologous to pap and related pilin operons. J Bacteriol (1993) 1.52
The Escherichia coli heat shock proteins GroEL and GroES modulate the folding of the beta-lactamase precursor. EMBO J (1990) 1.50
Escherichia coli DnaK protein possesses a 5'-nucleotidase activity that is inhibited by AppppA. J Bacteriol (1986) 1.46
Mutational analysis and properties of the msbA gene of Escherichia coli, coding for an essential ABC family transporter. Mol Microbiol (1996) 1.44
The htrM gene, whose product is essential for Escherichia coli viability only at elevated temperatures, is identical to the rfaD gene. Nucleic Acids Res (1991) 1.43
On the mechanism of FtsH-dependent degradation of the sigma 32 transcriptional regulator of Escherichia coli and the role of the Dnak chaperone machine. Mol Microbiol (1999) 1.42
Evidence that the two Escherichia coli groE morphogenetic gene products interact in vivo. J Bacteriol (1982) 1.37
The DnaJ chaperone catalytically activates the DnaK chaperone to preferentially bind the sigma 32 heat shock transcriptional regulator. Proc Natl Acad Sci U S A (1995) 1.35
The lethal phenotype caused by null mutations in the Escherichia coli htrB gene is suppressed by mutations in the accBC operon, encoding two subunits of acetyl coenzyme A carboxylase. J Bacteriol (1992) 1.35
arc-dependent thermal regulation and extragenic suppression of the Escherichia coli cytochrome d operon. J Bacteriol (1992) 1.31
Positive control of the two-component RcsC/B signal transduction network by DjlA: a member of the DnaJ family of molecular chaperones in Escherichia coli. Mol Microbiol (1997) 1.29
Identification of the heat-inducible protein C15.4 as the groES gene product in Escherichia coli. J Bacteriol (1983) 1.29
Bacteriophage lambda replication proteins: formation of a mixed oligomer and binding to the origin of lambda DNA. Mol Gen Genet (1984) 1.27
Bacteriophage T4 encodes a co-chaperonin that can substitute for Escherichia coli GroES in protein folding. Nature (1994) 1.26
Sequencing, mutational analysis, and transcriptional regulation of the Escherichia coli htrB gene. Mol Microbiol (1991) 1.24
Enzymology of the pre-priming steps in lambda dv DNA replication in vitro. J Biol Chem (1987) 1.23
Initiation of lambda DNA replication. The Escherichia coli small heat shock proteins, DnaJ and GrpE, increase DnaK's affinity for the lambda P protein. J Biol Chem (1993) 1.20
The Escherichia coli htrP gene product is essential for bacterial growth at high temperatures: mapping, cloning, sequencing, and transcriptional regulation of htrP. J Bacteriol (1991) 1.16
Identification, cloning, and characterization of the Escherichia coli sohA gene, a suppressor of the htrA (degP) null phenotype. J Bacteriol (1990) 1.12
The importance of a mobile loop in regulating chaperonin/ co-chaperonin interaction: humans versus Escherichia coli. J Biol Chem (2000) 1.11
Synthesis of a select group of proteins by Neisseria gonorrhoeae in response to thermal stress. Infect Immun (1990) 1.11
ATP hydrolysis is required for the DnaJ-dependent activation of DnaK chaperone for binding to both native and denatured protein substrates. J Biol Chem (1995) 1.10
Interplay of structure and disorder in cochaperonin mobile loops. Proc Natl Acad Sci U S A (1996) 1.10
Sequence analysis and phenotypic characterization of groEL mutations that block lambda and T4 bacteriophage growth. J Bacteriol (1993) 1.08
The ins and outs of a molecular chaperone machine. Trends Biochem Sci (1998) 1.07
The essential Escherichia coli msgB gene, a multicopy suppressor of a temperature-sensitive allele of the heat shock gene grpE, is identical to dapE. J Bacteriol (1992) 1.05
Isolation and characterization of the Escherichia coli htrD gene, whose product is required for growth at high temperatures. J Bacteriol (1992) 1.04
DjlA is a third DnaK co-chaperone of Escherichia coli, and DjlA-mediated induction of colanic acid capsule requires DjlA-DnaK interaction. J Biol Chem (2000) 1.01
Isolation and characterization of point mutations in the Escherichia coli grpE heat shock gene. J Bacteriol (1994) 1.00
The E. coli dnaA initiation protein: a protein for all seasons. Trends Genet (1989) 1.00
Compensatory changes in GroEL/Gp31 affinity as a mechanism for allele-specific genetic interaction. J Biol Chem (1999) 0.98
Structure-function analysis of the zinc-binding region of the Clpx molecular chaperone. J Biol Chem (2001) 0.98
Genetic and biochemical characterization of mutations affecting the carboxy-terminal domain of the Escherichia coli molecular chaperone DnaJ. Mol Microbiol (1998) 0.98
The djlA gene acts synergistically with dnaJ in promoting Escherichia coli growth. J Bacteriol (2001) 0.97
Bacteriophage lambda cloning vehicles for studies of genetic recombination. Gene (1980) 0.96
Purification and properties of the Escherichia coli heat shock protein, HtpG. J Biol Chem (1989) 0.96
Structure-function analyses of the Ssc1p, Mdj1p, and Mge1p Saccharomyces cerevisiae mitochondrial proteins in Escherichia coli. J Bacteriol (1997) 0.96
The oligomeric structure of GroEL/GroES is required for biologically significant chaperonin function in protein folding. Nat Struct Biol (1998) 0.96
Structure-function analysis of the Escherichia coli GrpE heat shock protein. EMBO J (1996) 0.95
Identification of important amino acid residues that modulate binding of Escherichia coli GroEL to its various cochaperones. Genetics (2001) 0.95