Sukanto Sinha

Author PubWeight™ 16.50‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease. J Biol Chem 2006 4.06
2 Partial reduction of BACE1 has dramatic effects on Alzheimer plaque and synaptic pathology in APP Transgenic Mice. J Biol Chem 2007 2.22
3 BACE1 gene deletion: impact on behavioral function in a model of Alzheimer's disease. Neurobiol Aging 2007 1.17
4 Hyperglycemia-induced cerebral hematoma expansion is mediated by plasma kallikrein. Nat Med 2011 1.10
5 Antagonistic effects of beta-site amyloid precursor protein-cleaving enzymes 1 and 2 on beta-amyloid peptide production in cells. J Biol Chem 2003 1.01
6 Human beta-secretase (BACE) and BACE inhibitors. J Med Chem 2003 1.00
7 Plasma kallikrein mediates angiotensin II type 1 receptor-stimulated retinal vascular permeability. Hypertension 2009 0.99
8 Plasma kallikrein mediates retinal vascular dysfunction and induces retinal thickening in diabetic rats. Diabetes 2011 0.96
9 Design, synthesis, and crystal structure of hydroxyethyl secondary amine-based peptidomimetic inhibitors of human beta-secretase. J Med Chem 2007 0.92
10 Design of substrate-based inhibitors of human beta-secretase. J Med Chem 2002 0.87
11 Design and synthesis of cell potent BACE-1 inhibitors: structure-activity relationship of P1' substituents. Bioorg Med Chem Lett 2009 0.85
12 Design and synthesis of statine-based cell-permeable peptidomimetic inhibitors of human beta-secretase. J Med Chem 2003 0.81
13 Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: structure-activity relationship of the aryl region. Bioorg Med Chem Lett 2010 0.80
14 Improving the permeability of the hydroxyethylamine BACE-1 inhibitors: structure-activity relationship of P2' substituents. Bioorg Med Chem Lett 2010 0.77