Design and synthesis of cell potent BACE-1 inhibitors: structure-activity relationship of P1' substituents.

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🔗 View Article (PMID 19811916)

Published in Bioorg Med Chem Lett on September 19, 2009

Authors

Jennifer M Sealy1, Anh P Truong, Luke Tso, Gary D Probst, Jose Aquino, Roy K Hom, Barbara M Jagodzinska, Darren Dressen, David W G Wone, Louis Brogley, Varghese John, Jay S Tung, Michael A Pleiss, John A Tucker, Andrei W Konradi, Michael S Dappen, Gergely Toth, Hu Pan, Lany Ruslim, Jim Miller, Michael P Bova, Sukanto Sinha, Kevin P Quinn, John-Michael Sauer

Author Affiliations

1: Department of Medicinal Chemistry, Elan Pharmaceuticals, 180 Oyster Point Boulevard, South San Francisco, CA 94080, USA.

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