Published in Cancer Res on July 01, 2007
The peroxidase activity of mitochondrial superoxide dismutase. Free Radic Biol Med (2012) 2.14
Ionizing radiation-induced metabolic oxidative stress and prolonged cell injury. Cancer Lett (2011) 1.81
Redox control of the cell cycle in health and disease. Antioxid Redox Signal (2009) 1.72
Manganese superoxide dismutase activity regulates transitions between quiescent and proliferative growth. Aging Cell (2008) 1.47
Prevention of diabetic nephropathy in Ins2(+/)⁻(AkitaJ) mice by the mitochondria-targeted therapy MitoQ. Biochem J (2010) 1.40
Oxidative stress promotes pathologic polyploidization in nonalcoholic fatty liver disease. J Clin Invest (2015) 1.17
Glutathione-dependent reductive stress triggers mitochondrial oxidation and cytotoxicity. FASEB J (2011) 1.16
Catalase ameliorates polychlorinated biphenyl-induced cytotoxicity in nonmalignant human breast epithelial cells. Free Radic Biol Med (2008) 1.03
Quantitative redox biology: an approach to understand the role of reactive species in defining the cellular redox environment. Cell Biochem Biophys (2013) 0.98
Oxidative stress: a required condition for thyroid cell proliferation. Am J Pathol (2010) 0.97
Differential expression of NADPH oxidases in megakaryocytes and their role in polyploidy. Blood (2009) 0.93
Mitochondrial DNA depletion induces radioresistance by suppressing G2 checkpoint activation in human pancreatic cancer cells. Radiat Res (2009) 0.93
Hepatic stellate cells' involvement in progenitor-mediated liver regeneration. Lab Invest (2010) 0.92
Particulate matter exposure exacerbates high glucose-induced cardiomyocyte dysfunction through ROS generation. PLoS One (2011) 0.92
Luteoloside suppresses proliferation and metastasis of hepatocellular carcinoma cells by inhibition of NLRP3 inflammasome. PLoS One (2014) 0.90
Radical decisions in cancer: redox control of cell growth and death. Cancers (Basel) (2012) 0.90
Manganese superoxide dismutase regulates a redox cycle within the cell cycle. Antioxid Redox Signal (2013) 0.90
A role for virally induced reactive oxygen species in Kaposi's sarcoma herpesvirus tumorigenesis. Antioxid Redox Signal (2012) 0.89
The p53/p21(WAF/CIP) pathway mediates oxidative stress and senescence in dyskeratosis congenita cells with telomerase insufficiency. Antioxid Redox Signal (2011) 0.89
Polychlorinated biphenyl induced ROS signaling delays the entry of quiescent human breast epithelial cells into the proliferative cycle. Free Radic Biol Med (2010) 0.87
2-(4-Chlorophenyl)benzo-1,4-quinone induced ROS-signaling inhibits proliferation in human non-malignant prostate epithelial cells. Environ Int (2010) 0.86
Phosphorylation and subcellular localization of p27Kip1 regulated by hydrogen peroxide modulation in cancer cells. PLoS One (2012) 0.86
Selenoprotein P inhibits radiation-induced late reactive oxygen species accumulation and normal cell injury. Int J Radiat Oncol Biol Phys (2013) 0.83
C10ORF10/DEPP, a transcriptional target of FOXO3, regulates ROS-sensitivity in human neuroblastoma. Mol Cancer (2014) 0.78
APE/Ref-1 makes fine-tuning of CD40-induced B cell proliferation. Mol Immunol (2008) 0.78
Thiol-based antioxidants elicit mitochondrial oxidation via respiratory complex III. Am J Physiol Cell Physiol (2015) 0.78
Reactive Oxygen Species Are Required for Human Mesenchymal Stem Cells to Initiate Proliferation after the Quiescence Exit. Oxid Med Cell Longev (2015) 0.78
Mitochondrial Fragmentation Due to Inhibition of Fusion Increases Cyclin B through Mitochondrial Superoxide Radicals. PLoS One (2015) 0.77
Mitochondria are the primary source of the H(2)O(2) signal for glucocorticoid-induced apoptosis of lymphoma cells. Exp Ther Med (2012) 0.76
N-acetyl-L-cysteine increases MnSOD activity and enhances the recruitment of quiescent human fibroblasts to the proliferation cycle during wound healing. Mol Biol Rep (2015) 0.75
Power Frequency Magnetic Fields Affect the p38 MAPK-Mediated Regulation of NB69 Cell Proliferation Implication of Free Radicals. Int J Mol Sci (2016) 0.75
Superoxide Dismutases in Pancreatic Cancer. Antioxidants (Basel) (2017) 0.75
Role for DNA methylation in the control of cell type specific maspin expression. Nat Genet (2002) 4.72
Disruption of an AP-2alpha binding site in an IRF6 enhancer is associated with cleft lip. Nat Genet (2008) 4.04
Vitamin E inhibits abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol (2005) 2.42
Human endothelial progenitor cells tolerate oxidative stress due to intrinsically high expression of manganese superoxide dismutase. Arterioscler Thromb Vasc Biol (2004) 2.39
Increased levels of superoxide and H2O2 mediate the differential susceptibility of cancer cells versus normal cells to glucose deprivation. Biochem J (2009) 2.35
Mutation of succinate dehydrogenase subunit C results in increased O2.-, oxidative stress, and genomic instability. Cancer Res (2006) 2.27
Oxidative stress in human abdominal aortic aneurysms: a potential mediator of aneurysmal remodeling. Arterioscler Thromb Vasc Biol (2002) 2.01
Mitochondrial O2*- and H2O2 mediate glucose deprivation-induced stress in human cancer cells. J Biol Chem (2004) 1.94
Manganese superoxide dismutase-mediated gene expression in radiation-induced adaptive responses. Mol Cell Biol (2003) 1.80
Redox control of the cell cycle in health and disease. Antioxid Redox Signal (2009) 1.72
Identification of a functional peroxisome proliferator-activated receptor response element in the rat catalase promoter. Mol Endocrinol (2002) 1.67
Redox regulation of the G1 to S phase transition in the mouse embryo fibroblast cell cycle. Cancer Res (2003) 1.62
The role of manganese superoxide dismutase in the growth of pancreatic adenocarcinoma. Cancer Res (2003) 1.58
Epigenetic silencing of DSC3 is a common event in human breast cancer. Breast Cancer Res (2005) 1.50
Mutant p53 and aberrant cytosine methylation cooperate to silence gene expression. Oncogene (2003) 1.48
Activation of matrix metalloproteinase-2 by overexpression of manganese superoxide dismutase in human breast cancer MCF-7 cells involves reactive oxygen species. J Biol Chem (2002) 1.47
Manganese superoxide dismutase activity regulates transitions between quiescent and proliferative growth. Aging Cell (2008) 1.47
Suppression of the malignant phenotype in human pancreatic cancer cells by the overexpression of manganese superoxide dismutase. Mol Cancer Ther (2003) 1.45
MnSOD inhibits proline oxidase-induced apoptosis in colorectal cancer cells. Carcinogenesis (2005) 1.39
The rate of oxygen utilization by cells. Free Radic Biol Med (2011) 1.36
An epigenetic perspective on the free radical theory of development. Free Radic Biol Med (2007) 1.35
Manganese superoxide dismutase overexpression inhibits the growth of androgen-independent prostate cancer cells. Oncogene (2005) 1.30
A redox signature score identifies diffuse large B-cell lymphoma patients with a poor prognosis. Blood (2005) 1.28
Identification of primary gene targets of TFAP2C in hormone responsive breast carcinoma cells. Genes Chromosomes Cancer (2010) 1.27
Manganese superoxide dismutase suppresses hypoxic induction of hypoxia-inducible factor-1alpha and vascular endothelial growth factor. Oncogene (2005) 1.26
Inhibition of glutamate cysteine ligase activity sensitizes human breast cancer cells to the toxicity of 2-deoxy-D-glucose. Cancer Res (2006) 1.25
Inhibition of cell growth by overexpression of manganese superoxide dismutase (MnSOD) in human pancreatic carcinoma. Free Radic Res (2004) 1.25
The redox basis of epigenetic modifications: from mechanisms to functional consequences. Antioxid Redox Signal (2011) 1.24
Dicumarol inhibition of NADPH:quinone oxidoreductase induces growth inhibition of pancreatic cancer via a superoxide-mediated mechanism. Cancer Res (2003) 1.23
Epigenetic silencing of SOD2 by histone modifications in human breast cancer cells. Free Radic Biol Med (2008) 1.20
Manganese superoxide dismutase protects the proliferative capacity of confluent normal human fibroblasts. J Biol Chem (2005) 1.19
Thioredoxin reductase regulates AP-1 activity as well as thioredoxin nuclear localization via active cysteines in response to ionizing radiation. Oncogene (2002) 1.18
Targeting NAD(P)H:quinone oxidoreductase (NQO1) in pancreatic cancer. Mol Carcinog (2005) 1.18
Modulation of reactive oxygen species in pancreatic cancer. Clin Cancer Res (2007) 1.18
Granule stores from cellubrevin/VAMP-3 null mouse platelets exhibit normal stimulus-induced release. Blood (2003) 1.18
DNA methylation changes in ovarian cancer are cumulative with disease progression and identify tumor stage. BMC Med Genomics (2008) 1.17
A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability. J Biol Chem (2006) 1.16
Mutant SOD1-induced neuronal toxicity is mediated by increased mitochondrial superoxide levels. J Neurochem (2007) 1.16
Overexpression of manganese or copper-zinc superoxide dismutase inhibits breast cancer growth. Free Radic Biol Med (2006) 1.16
Mitochondrial ROS and radiation induced transformation in mouse embryonic fibroblasts. Cancer Biol Ther (2009) 1.15
Delayed radioprotection by NFkappaB-mediated induction of Sod2 (MnSOD) in SA-NH tumor cells after exposure to clinically used thiol-containing drugs. Radiat Res (2004) 1.15
Elevated mitochondrial superoxide disrupts normal T cell development, impairing adaptive immune responses to an influenza challenge. Free Radic Biol Med (2010) 1.13
Apoptosis induced by selenomethionine and methioninase is superoxide mediated and p53 dependent in human prostate cancer cells. Mol Cancer Ther (2006) 1.13
ZEB1 coordinately regulates laminin-332 and {beta}4 integrin expression altering the invasive phenotype of prostate cancer cells. J Biol Chem (2010) 1.12
Deficiency of glutathione peroxidase-1 sensitizes hyperhomocysteinemic mice to endothelial dysfunction. Arterioscler Thromb Vasc Biol (2002) 1.11
Epigenetic regulation of manganese superoxide dismutase expression in human breast cancer cells. Epigenetics (2006) 1.11
Radiosensitizing and anti-proliferative effects of resveratrol in two human cervical tumor cell lines. Cancer Lett (2002) 1.10
Metabolic defects provide a spark for the epigenetic switch in cancer. Free Radic Biol Med (2009) 1.10
Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells. BMC Cancer (2012) 1.10
Inhibition of EZH2 suppresses self-renewal and induces radiation sensitivity in atypical rhabdoid teratoid tumor cells. Neuro Oncol (2012) 1.09
Xanthine oxidase-derived ROS upregulate Egr-1 via ERK1/2 in PA smooth muscle cells; model to test impact of extracellular ROS in chronic hypoxia. PLoS One (2011) 1.09
Tissue-specific changes in H19 methylation and expression in mice with hyperhomocysteinemia. J Biol Chem (2005) 1.09
Polychlorinated-biphenyl-induced oxidative stress and cytotoxicity can be mitigated by antioxidants after exposure. Free Radic Biol Med (2009) 1.09
Overexpression of extracellular superoxide dismutase attenuates heparanase expression and inhibits breast carcinoma cell growth and invasion. Cancer Res (2009) 1.08
A role for manganese superoxide dismutase in apoptosis after photosensitization. Biochem Biophys Res Commun (2005) 1.07
A nucleotide insertion in the transcriptional regulatory region of FADS2 gives rise to human fatty acid delta-6-desaturase deficiency. J Lipid Res (2003) 1.05
Mitochondrial production of reactive oxygen species mediate dicumarol-induced cytotoxicity in cancer cells. J Biol Chem (2006) 1.05
Expression of p53 enhances selenite-induced superoxide production and apoptosis in human prostate cancer cells. Cancer Res (2006) 1.05
Aberrant methylation of the maspin promoter is an early event in human breast cancer. Neoplasia (2004) 1.05
Mitochondrial complex II dysfunction can contribute significantly to genomic instability after exposure to ionizing radiation. Radiat Res (2009) 1.04
Human pancreatic carcinoma cells activate maspin expression through loss of epigenetic control. Neoplasia (2003) 1.04
Catalase ameliorates polychlorinated biphenyl-induced cytotoxicity in nonmalignant human breast epithelial cells. Free Radic Biol Med (2008) 1.03
Mitochondria, energetics, epigenetics, and cellular responses to stress. Environ Health Perspect (2014) 1.03
Extracellular redox state regulates features associated with prostate cancer cell invasion. Cancer Res (2008) 1.03
Human Chondrosarcoma Cells Acquire an Epithelial-Like Gene Expression Pattern via an Epigenetic Switch: Evidence for Mesenchymal-Epithelial Transition during Sarcomagenesis. Sarcoma (2011) 1.03
Manganese superoxide dismutase modulates hypoxia-inducible factor-1 alpha induction via superoxide. Cancer Res (2008) 1.02
Epigenetic regulation of maspin expression in human ovarian carcinoma cells. Gynecol Oncol (2006) 1.01
Targeting the enhancer of zeste homologue 2 in medulloblastoma. Int J Cancer (2012) 1.01
Mn-superoxide dismutase overexpression enhances G2 accumulation and radioresistance in human oral squamous carcinoma cells. Antioxid Redox Signal (2006) 1.01
Overexpression of copper zinc superoxide dismutase suppresses human glioma cell growth. Cancer Res (2002) 1.01