Published in Nat Struct Mol Biol on July 15, 2007
Mouse Piwi interactome identifies binding mechanism of Tdrkh Tudor domain to arginine methylated Miwi. Proc Natl Acad Sci U S A (2009) 1.73
The C-terminal domain of RNA polymerase II is modified by site-specific methylation. Science (2011) 1.72
Deciphering arginine methylation: Tudor tells the tale. Nat Rev Mol Cell Biol (2011) 1.69
Metacaspases. Cell Death Differ (2011) 1.67
Tudor staphylococcal nuclease is an evolutionarily conserved component of the programmed cell death degradome. Nat Cell Biol (2009) 1.60
Structural basis for methylarginine-dependent recognition of Aubergine by Tudor. Genes Dev (2010) 1.52
Structural basis for recognition of arginine methylated Piwi proteins by the extended Tudor domain. Proc Natl Acad Sci U S A (2010) 1.40
TDRD3, a novel Tudor domain-containing protein, localizes to cytoplasmic stress granules. Hum Mol Genet (2008) 1.36
Identification of staphylococcal nuclease domain-containing 1 (SND1) as a Metadherin-interacting protein with metastasis-promoting functions. J Biol Chem (2011) 1.33
Vreteno, a gonad-specific protein, is essential for germline development and primary piRNA biogenesis in Drosophila. Development (2011) 1.19
Structural and functional insights into human Tudor-SN, a key component linking RNA interference and editing. Nucleic Acids Res (2008) 1.17
Arginine methylation-dependent reader-writer interplay governs growth control by E2F-1. Mol Cell (2013) 1.12
RFX2 is a candidate downstream amplifier of A-MYB regulation in mouse spermatogenesis. BMC Dev Biol (2009) 1.05
Structure of an atypical Tudor domain in the Drosophila Polycomblike protein. Protein Sci (2010) 0.94
Structural properties of PAS domains from the KCNH potassium channels. PLoS One (2013) 0.94
Tudor staphylococcal nuclease (Tudor-SN) participates in small ribonucleoprotein (snRNP) assembly via interacting with symmetrically dimethylated Sm proteins. J Biol Chem (2012) 0.92
Utilization of protein intrinsic disorder knowledge in structural proteomics. Biochim Biophys Acta (2012) 0.89
Salt bridges regulate both dimer formation and monomeric flexibility in HdeB and may have a role in periplasmic chaperone function. J Mol Biol (2011) 0.87
Solution structure and molecular interactions of lamin B receptor Tudor domain. J Biol Chem (2011) 0.83
Structural insights into the tumor-promoting function of the MTDH-SND1 complex. Cell Rep (2014) 0.83
Crystallization and preliminary crystallographic characterization of the PAS domains of EAG and ELK potassium channels. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.80
Sequence and structural analysis of 4SNc-Tudor domain protein from Takifugu Rubripes. Bioinformation (2009) 0.79
Organization of Plasmodium falciparum spliceosomal core complex and role of arginine methylation in its assembly. Malar J (2013) 0.78
Profiling of promoter occupancy by the SND1 transcriptional coactivator identifies downstream glycerolipid metabolic genes involved in TNFα response in human hepatoma cells. Nucleic Acids Res (2015) 0.77
Tudor staphylococcal nuclease drives chemoresistance of non-small cell lung carcinoma cells by regulating S100A11. Oncotarget (2015) 0.77
Tudor staphylococcal nuclease: biochemistry and functions. Cell Death Differ (2016) 0.76
Tudor-SN Interacts with Piwi Antagonistically in Regulating Spermatogenesis but Synergistically in Silencing Transposons in Drosophila. PLoS Genet (2016) 0.76
LncRNA-HIT Functions as an Epigenetic Regulator of Chondrogenesis through Its Recruitment of p100/CBP Complexes. PLoS Genet (2015) 0.75
The Tudor Staphylococcal Nuclease Protein of Entamoeba histolytica Participates in Transcription Regulation and Stress Response. Front Cell Infect Microbiol (2017) 0.75
Structure and domain organization of Drosophila Tudor. Cell Res (2014) 0.75
The Genomes of Oryza sativa: a history of duplications. PLoS Biol (2005) 7.67
Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Nat Genet (2009) 6.42
The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. Nature (2011) 6.21
Chronic stress promotes tumor growth and angiogenesis in a mouse model of ovarian carcinoma. Nat Med (2006) 6.18
A test of enhancing model accuracy in high-throughput crystallography. J Struct Funct Genomics (2005) 5.96
Curved EFC/F-BAR-domain dimers are joined end to end into a filament for membrane invagination in endocytosis. Cell (2007) 4.73
Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site. Nature (2009) 4.49
ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization. Proc Natl Acad Sci U S A (2009) 4.46
Protein production and purification. Nat Methods (2008) 3.97
Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation. Nat Genet (2013) 3.87
Trends in prevalence of HIV, syphilis, hepatitis C, hepatitis B, and sexual risk behavior among men who have sex with men. Results of 3 consecutive respondent-driven sampling surveys in Beijing, 2004 through 2006. J Acquir Immune Defic Syndr (2007) 3.83
Substrate modulus directs neural stem cell behavior. Biophys J (2008) 3.81
Structural basis for the recognition of blood group trisaccharides by norovirus. J Virol (2007) 3.58
Stress hormone-mediated invasion of ovarian cancer cells. Clin Cancer Res (2006) 3.58
Sequence polymorphisms cause many false cis eQTLs. PLoS One (2007) 3.54
Crystal structure of mitochondrial respiratory membrane protein complex II. Cell (2005) 3.44
Mineralocorticoid receptor antagonism in the treatment of chronic central serous chorioretinopathy: a pilot study. Retina (2013) 3.42
Controlling cell behavior electrically: current views and future potential. Physiol Rev (2005) 3.34
Effects of raf kinase inhibitor protein expression on suppression of prostate cancer metastasis. J Natl Cancer Inst (2003) 3.19
The phosphothreonine lyase activity of a bacterial type III effector family. Science (2007) 3.18
PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death. Mol Cell (2009) 3.17
CTLs are targeted to kill beta cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope. J Clin Invest (2008) 3.11
Prognostic significance of tumorigenic cells with mesenchymal features in pancreatic adenocarcinoma. J Natl Cancer Inst (2010) 3.08
Identification of multivesicular bodies as prevacuolar compartments in Nicotiana tabacum BY-2 cells. Plant Cell (2004) 3.08
Serial determination of glomerular filtration rate in conscious mice using FITC-inulin clearance. Am J Physiol Renal Physiol (2003) 3.06
Crystal structure of the polymerase PA(C)-PB1(N) complex from an avian influenza H5N1 virus. Nature (2008) 3.06
The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor. Proc Natl Acad Sci U S A (2003) 3.02
Crystal structure of the cytoskeleton-associated protein glycine-rich (CAP-Gly) domain. J Biol Chem (2002) 3.01
Structure of RSV fusion glycoprotein trimer bound to a prefusion-specific neutralizing antibody. Science (2013) 2.95
A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71. Nat Struct Mol Biol (2012) 2.81
Genetical genomics: spotlight on QTL hotspots. PLoS Genet (2008) 2.63
JAK2V617F-mediated phosphorylation of PRMT5 downregulates its methyltransferase activity and promotes myeloproliferation. Cancer Cell (2011) 2.56
Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding. Immunity (2012) 2.47
Interleukin 6 and interleukin 8 as potential biomarkers for oral cavity and oropharyngeal squamous cell carcinoma. Arch Otolaryngol Head Neck Surg (2004) 2.46
Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models--association with liver and adipose tissue effects. Am J Physiol Endocrinol Metab (2009) 2.39
Large-scale identification of proteins in human salivary proteome by liquid chromatography/mass spectrometry and two-dimensional gel electrophoresis-mass spectrometry. Proteomics (2005) 2.34
PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons. PLoS One (2008) 2.33
Norepinephrine up-regulates the expression of vascular endothelial growth factor, matrix metalloproteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumor cells. Cancer Res (2006) 2.32
Rejection of unfair offers in the ultimatum game is no evidence of strong reciprocity. Proc Natl Acad Sci U S A (2012) 2.31
Use of electrochemical DNA biosensors for rapid molecular identification of uropathogens in clinical urine specimens. J Clin Microbiol (2006) 2.27
An analysis of the indications for cesarean section in a teaching hospital in China. Eur J Obstet Gynecol Reprod Biol (2013) 2.26
Dynamics of signaling by PKA. Biochim Biophys Acta (2005) 2.26
Mutant prominin 1 found in patients with macular degeneration disrupts photoreceptor disk morphogenesis in mice. J Clin Invest (2008) 2.24
The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling. Nat Struct Mol Biol (2011) 2.20
The Human Ageing Genomic Resources: online databases and tools for biogerontologists. Aging Cell (2008) 2.19
Automatic detection and recognition of signs from natural scenes. IEEE Trans Image Process (2004) 2.19
The Janus kinases (Jaks). Genome Biol (2004) 2.18
Reconstituted membrane fusion requires regulatory lipids, SNAREs and synergistic SNARE chaperones. EMBO J (2008) 2.16
An oligonucleotide microarray for microRNA expression analysis based on labeling RNA with quantum dot and nanogold probe. Nucleic Acids Res (2005) 2.15
The pseudokinase domain is required for suppression of basal activity of Jak2 and Jak3 tyrosine kinases and for cytokine-inducible activation of signal transduction. J Biol Chem (2002) 2.14
Detectable minimal residual disease before hematopoietic cell transplantation is prognostic but does not preclude cure for children with very-high-risk leukemia. Blood (2012) 2.14
Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma. Genome Res (2013) 2.12
The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response. Nat Immunol (2012) 2.11
Computational tools for copy number variation (CNV) detection using next-generation sequencing data: features and perspectives. BMC Bioinformatics (2013) 2.07
Effects of D-4F on vasodilation and vessel wall thickness in hypercholesterolemic LDL receptor-null and LDL receptor/apolipoprotein A-I double-knockout mice on Western diet. Circ Res (2005) 2.06
Medium scale integration of molecular logic gates in an automaton. Nano Lett (2006) 1.98
Crystal structures of a ligand-free MthK gating ring: insights into the ligand gating mechanism of K+ channels. Cell (2006) 1.98
Activation of G protein-coupled receptor 43 in adipocytes leads to inhibition of lipolysis and suppression of plasma free fatty acids. Endocrinology (2008) 1.97
Somatic mutations in BRCA1 and BRCA2 could expand the number of patients that benefit from poly (ADP ribose) polymerase inhibitors in ovarian cancer. J Clin Oncol (2010) 1.95
Characterization of RNA in saliva. Clin Chem (2006) 1.93
Expression quantitative trait loci are highly sensitive to cellular differentiation state. PLoS Genet (2009) 1.92
Regulation of Jak2 through the ubiquitin-proteasome pathway involves phosphorylation of Jak2 on Y1007 and interaction with SOCS-1. Mol Cell Biol (2002) 1.92
A Minimally Invasive Procedure for Axillary Osmidrosis: Subcutaneous Curettage Combined with Trimming Through a Small Incision. Aesthetic Plast Surg (2014) 1.92
VEGF-B is dispensable for blood vessel growth but critical for their survival, and VEGF-B targeting inhibits pathological angiogenesis. Proc Natl Acad Sci U S A (2009) 1.91
Monocyte chemotactic protein-1 (MCP-1) acts as a paracrine and autocrine factor for prostate cancer growth and invasion. Prostate (2006) 1.90
Efficacy and antivascular effects of EphA2 reduction with an agonistic antibody in ovarian cancer. J Natl Cancer Inst (2006) 1.87
The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage. Genome Biol (2013) 1.87
Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture. Dis Model Mech (2011) 1.87
Automated chemical crystallography. J Am Chem Soc (2010) 1.86
Novel insights into K+ selectivity from high-resolution structures of an open K+ channel pore. Nat Struct Mol Biol (2010) 1.86
TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo. EMBO J (2007) 1.85
Determination of food portion size by image processing. Conf Proc IEEE Eng Med Biol Soc (2008) 1.84
Recombinant E. coli prototype strains for in vivo glycorandomization. ACS Chem Biol (2010) 1.82
Autoinhibition of Jak2 tyrosine kinase is dependent on specific regions in its pseudokinase domain. Mol Biol Cell (2003) 1.79
Monocyte chemotactic protein-1 mediates prostate cancer-induced bone resorption. Cancer Res (2007) 1.79
Metastasis suppressor gene Raf kinase inhibitor protein (RKIP) is a novel prognostic marker in prostate cancer. Prostate (2006) 1.78
Sox2 protects neural stem cells from apoptosis via up-regulating survivin expression. Biochem J (2013) 1.77
Identification and functional characterization of allosteric agonists for the G protein-coupled receptor FFA2. Mol Pharmacol (2008) 1.75
T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities. J Biol Chem (2002) 1.75
Technical factors related to the incidence of adjacent superior segment facet joint violation after transpedicular instrumentation in the lumbar spine. Eur Spine J (2008) 1.75
Structural basis for regulation of protein phosphatase 1 by inhibitor-2. J Biol Chem (2007) 1.74
Structure of the APPL1 BAR-PH domain and characterization of its interaction with Rab5. EMBO J (2007) 1.74
DNA ploidy cytometry testing for cervical cancer screening in China (DNACIC Trial): a prospective randomized, controlled trial. Clin Cancer Res (2009) 1.73
Design of wide-spectrum inhibitors targeting coronavirus main proteases. PLoS Biol (2005) 1.73
A feasibility study of cerebral oximetry during in-hospital mechanical and manual cardiopulmonary resuscitation*. Crit Care Med (2014) 1.70
Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC. Nat Genet (2010) 1.69
Comparative genomics reveals a deep-sea sediment-adapted life style of Pseudoalteromonas sp. SM9913. ISME J (2010) 1.69
Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis. Proc Natl Acad Sci U S A (2011) 1.69
Gene alterations identified by expression profiling in tumor-associated endothelial cells from invasive ovarian carcinoma. Cancer Res (2007) 1.68
Insights into SARS-CoV transcription and replication from the structure of the nsp7-nsp8 hexadecamer. Nat Struct Mol Biol (2005) 1.68
High success rate of hematopoietic cell transplantation regardless of donor source in children with very high-risk leukemia. Blood (2011) 1.68
Rha1, an Arabidopsis Rab5 homolog, plays a critical role in the vacuolar trafficking of soluble cargo proteins. Plant Cell (2003) 1.67
The p53 inhibitors MDM2/MDMX complex is required for control of p53 activity in vivo. Proc Natl Acad Sci U S A (2011) 1.66
Endocytic receptor LRP together with tPA and PAI-1 coordinates Mac-1-dependent macrophage migration. EMBO J (2006) 1.66
Identification of p100 as a coactivator for STAT6 that bridges STAT6 with RNA polymerase II. EMBO J (2002) 1.65