Published in ACS Chem Biol on October 22, 2010
Using simple donors to drive the equilibria of glycosyltransferase-catalyzed reactions. Nat Chem Biol (2011) 1.15
A comprehensive review of glycosylated bacterial natural products. Chem Soc Rev (2015) 1.13
Glycosyltransferase structural biology and its role in the design of catalysts for glycosylation. Curr Opin Biotechnol (2011) 1.07
Expanding the nucleotide and sugar 1-phosphate promiscuity of nucleotidyltransferase RmlA via directed evolution. J Biol Chem (2011) 0.96
Enzymatic glycosylation of nonbenzoquinone geldanamycin analogs via Bacillus UDP-glycosyltransferase. Appl Environ Microbiol (2012) 0.94
Natural product disaccharide engineering through tandem glycosyltransferase catalysis reversibility and neoglycosylation. Org Lett (2012) 0.91
Broadening the scope of glycosyltransferase-catalyzed sugar nucleotide synthesis. Proc Natl Acad Sci U S A (2013) 0.88
Enzymatic synthesis of novel phloretin glucosides. Appl Environ Microbiol (2013) 0.87
Probing 3-hydroxyflavone for in vitro glycorandomization of flavonols by YjiC. Appl Environ Microbiol (2013) 0.86
Fermenting next generation glycosylated therapeutics. ACS Chem Biol (2011) 0.85
A simple strategy for glycosyltransferase-catalyzed aminosugar nucleotide synthesis. Chembiochem (2014) 0.82
Asymmetric enzymatic glycosylation of mitoxantrone. Org Lett (2011) 0.80
Glucosylation of isoflavonoids in engineered Escherichia coli. Mol Cells (2014) 0.79
Development of a universal glycosyltransferase assay amenable to high-throughput formats. Anal Biochem (2011) 0.79
Enzymatic Biosynthesis of Novel Resveratrol Glucoside and Glycoside Derivatives. Appl Environ Microbiol (2014) 0.78
Accessing Nature's diversity through metabolic engineering and synthetic biology. F1000Res (2016) 0.76
Discovering the distinct inhibitory effects between C4-epimeric glycosyl amino acids: new insight into the development of protein tyrosine phosphatase inhibitors. Glycoconj J (2011) 0.76
Recent biotechnological progress in enzymatic synthesis of glycosides. J Ind Microbiol Biotechnol (2013) 0.76
Identification of Neuroprotective Spoxazomicin and Oxachelin Glycosides via Chemoenzymatic Glycosyl-Scanning. J Nat Prod (2016) 0.75
Biosynthesis of three N-acetylaminosugar-conjugated flavonoids using engineered Escherichia coli. Microb Cell Fact (2016) 0.75
Glycosyltransferase-Mediated Exchange of Rare Microbial Sugars with Natural Products. Front Microbiol (2016) 0.75
Natural-product sugar biosynthesis and enzymatic glycodiversification. Angew Chem Int Ed Engl (2008) 2.69
Expanding the promiscuity of a natural-product glycosyltransferase by directed evolution. Nat Chem Biol (2007) 2.31
Opportunities and challenges in synthetic oligosaccharide and glycoconjugate research. Nat Chem (2009) 2.09
Production of the antitumor drug epirubicin (4'-epidoxorubicin) and its precursor by a genetically engineered strain of Streptomyces peucetius. Nat Biotechnol (1998) 1.97
Optimizing glycosyltransferase specificity via "hot spot" saturation mutagenesis presents a catalyst for novobiocin glycorandomization. Chem Biol (2008) 1.84
Exploiting the reversibility of natural product glycosyltransferase-catalyzed reactions. Science (2006) 1.82
Antibiotic optimization via in vitro glycorandomization. Nat Biotechnol (2003) 1.41
Arabidopsis glycosyltransferases as biocatalysts in fermentation for regioselective synthesis of diverse quercetin glucosides. Biotechnol Bioeng (2004) 1.28
Engineering biosynthetic pathways for deoxysugars: branched-chain sugar pathways and derivatives from the antitumor tetracenomycin. Chem Biol (2004) 1.20
Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering. Proc Natl Acad Sci U S A (2002) 1.19
Probing the aglycon promiscuity of an engineered glycosyltransferase. Angew Chem Int Ed Engl (2008) 1.12
The in vitro characterization of the iterative avermectin glycosyltransferase AveBI reveals reaction reversibility and sugar nucleotide flexibility. J Am Chem Soc (2006) 1.12
Identification of a sugar flexible glycosyltransferase from Streptomyces olivaceus, the producer of the antitumor polyketide elloramycin. Chem Biol (2001) 1.10
Combining sugar biosynthesis genes for the generation of L- and D-amicetose and formation of two novel antitumor tetracenomycins. Chem Commun (Camb) (2005) 1.09
A high-throughput fluorescence-based glycosyltransferase screen and its application in directed evolution. Nat Protoc (2008) 1.06
Natural product glycosyltransferases: properties and applications. Adv Enzymol Relat Areas Mol Biol (2009) 1.06
Increasing carbohydrate diversity via amine oxidation: aminosugar, hydroxyaminosugar, nitrososugar, and nitrosugar biosynthesis in bacteria. Curr Opin Chem Biol (2008) 1.05
Enhancing the latent nucleotide triphosphate flexibility of the glucose-1-phosphate thymidylyltransferase RmlA. J Biol Chem (2007) 1.04
Digitoxosyltetracenomycin C and glucosyltetracenomycin C, two novel elloramycin analogues obtained by exploring the sugar donor substrate specificity of glycosyltransferase ElmGT. J Nat Prod (2002) 1.01
Substrate specificity of NovM: implications for novobiocin biosynthesis and glycorandomization. Org Lett (2003) 1.01
Structure-based engineering of E. coli galactokinase as a first step toward in vivo glycorandomization. Chem Biol (2005) 0.98
Creation of the first anomeric D/L-sugar kinase by means of directed evolution. Proc Natl Acad Sci U S A (2003) 0.97
lpp deletion as a permeabilization method. Biotechnol Bioeng (2007) 0.97
The synthesis of small-molecule rhamnosides through the rational design of a whole-cell biocatalysis system. Chembiochem (2006) 0.94
The in vitro characterization of the erythronolide mycarosyltransferase EryBV and its utility in macrolide diversification. Chembiochem (2007) 0.92
Discovery of new biocatalysts for the glycosylation of terpenoid scaffolds. Chemistry (2008) 0.89
Regioselective synthesis of plant (iso)flavone glycosides in Escherichia coli. Appl Microbiol Biotechnol (2008) 0.86
Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation. Nat Genet (2013) 3.87
Prognostic significance of tumorigenic cells with mesenchymal features in pancreatic adenocarcinoma. J Natl Cancer Inst (2010) 3.08
A genomics-guided approach for discovering and expressing cryptic metabolic pathways. Nat Biotechnol (2003) 2.41
The calicheamicin gene cluster and its iterative type I enediyne PKS. Science (2002) 2.40
Expanding the promiscuity of a natural-product glycosyltransferase by directed evolution. Nat Chem Biol (2007) 2.31
Dynamics of signaling by PKA. Biochim Biophys Acta (2005) 2.26
Automatic detection and recognition of signs from natural scenes. IEEE Trans Image Process (2004) 2.19
Detectable minimal residual disease before hematopoietic cell transplantation is prognostic but does not preclude cure for children with very-high-risk leukemia. Blood (2012) 2.14
Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma. Genome Res (2013) 2.12
A Minimally Invasive Procedure for Axillary Osmidrosis: Subcutaneous Curettage Combined with Trimming Through a Small Incision. Aesthetic Plast Surg (2014) 1.92
Antitumor antibiotics: bleomycin, enediynes, and mitomycin. Chem Rev (2005) 1.91
Incorporation of glucose analogs by GtfE and GtfD from the vancomycin biosynthetic pathway to generate variant glycopeptides. Chem Biol (2002) 1.90
Optimizing glycosyltransferase specificity via "hot spot" saturation mutagenesis presents a catalyst for novobiocin glycorandomization. Chem Biol (2008) 1.84
Determination of food portion size by image processing. Conf Proc IEEE Eng Med Biol Soc (2008) 1.84
The hedamycin locus implicates a novel aromatic PKS priming mechanism. Chem Biol (2004) 1.82
Exploiting the reversibility of natural product glycosyltransferase-catalyzed reactions. Science (2006) 1.82
Structural basis for regulation of protein phosphatase 1 by inhibitor-2. J Biol Chem (2007) 1.74
DNA ploidy cytometry testing for cervical cancer screening in China (DNACIC Trial): a prospective randomized, controlled trial. Clin Cancer Res (2009) 1.73
A feasibility study of cerebral oximetry during in-hospital mechanical and manual cardiopulmonary resuscitation*. Crit Care Med (2014) 1.70
High success rate of hematopoietic cell transplantation regardless of donor source in children with very high-risk leukemia. Blood (2011) 1.68
The p53 inhibitors MDM2/MDMX complex is required for control of p53 activity in vivo. Proc Natl Acad Sci U S A (2011) 1.66
Findings from 2010 Global Adult Tobacco Survey: implementation of MPOWER policy in China. Biomed Environ Sci (2010) 1.65
The three-dimensional structures of antagonistic and agonistic forms of the glucocorticoid receptor ligand-binding domain: RU-486 induces a transconformation that leads to active antagonism. J Biol Chem (2003) 1.61
HAT4, a Golgi apparatus-anchored B-type histone acetyltransferase, acetylates free histone H4 and facilitates chromatin assembly. Mol Cell (2011) 1.59
Phosphorylation reaction in cAPK protein kinase-free energy quantum mechanical/molecular mechanics simulations. J Phys Chem B (2007) 1.55
Growth inhibition and radiosensitization of glioblastoma and lung cancer cells by small interfering RNA silencing of tumor necrosis factor receptor-associated factor 2. Cancer Res (2008) 1.55
Antiviral treatment for preventing postherpetic neuralgia. Cochrane Database Syst Rev (2009) 1.52
Nuclear or cytoplasmic expression of survivin: what is the significance? Int J Cancer (2005) 1.52
Enhancing the anticancer properties of cardiac glycosides by neoglycorandomization. Proc Natl Acad Sci U S A (2005) 1.49
Safety and immunogenicity of live attenuated and inactivated influenza vaccines in children with cancer. J Infect Dis (2011) 1.49
Rapid PCR amplification of minimal enediyne polyketide synthase cassettes leads to a predictive familial classification model. Proc Natl Acad Sci U S A (2003) 1.48
Enzymatic tools for engineering natural product glycosylation. Curr Opin Chem Biol (2006) 1.47
The multifunctional human p100 protein 'hooks' methylated ligands. Nat Struct Mol Biol (2007) 1.46
Association between two polymorphisms of ABCB1 and breast cancer risk in the current studies: a meta-analysis. Breast Cancer Res Treat (2010) 1.46
Expression levels of phosphatase and tensin homolog deleted on chromosome 10 (PTEN) and focal adhesion kinase in patients with multiple myeloma and their relationship to clinical stage and extramedullary infiltration. Leuk Lymphoma (2012) 1.45
Antibiotic optimization via in vitro glycorandomization. Nat Biotechnol (2003) 1.41
Dichloridobis[1-(2-methyl-benzimidazol-1-ylmethyl-κN)benzotriazole]mercury(II). Acta Crystallogr Sect E Struct Rep Online (2009) 1.38
'Sweetening' natural products via glycorandomization. Curr Opin Biotechnol (2005) 1.38
The composition and structure of stones in enlarged prostatic utricles (EPU). J Androl (2010) 1.36
Tudor and nuclease-like domains containing protein p100 function as coactivators for signal transducer and activator of transcription 5. Mol Endocrinol (2003) 1.36
RebG- and RebM-catalyzed indolocarbazole diversification. Chembiochem (2006) 1.36
Validation of SAG/RBX2/ROC2 E3 ubiquitin ligase as an anticancer and radiosensitizing target. Clin Cancer Res (2010) 1.34
Enzymatic methods for glyco(diversification/randomization) of drugs and small molecules. Nat Prod Rep (2011) 1.33
Emodin enhances arsenic trioxide-induced apoptosis via generation of reactive oxygen species and inhibition of survival signaling. Cancer Res (2004) 1.33
The transcriptional co-activator protein p100 recruits histone acetyltransferase activity to STAT6 and mediates interaction between the CREB-binding protein and STAT6. J Biol Chem (2005) 1.31
Differentiation of a highly tumorigenic basal cell compartment in urothelial carcinoma. Stem Cells (2009) 1.30
PIAS proteins promote SUMO-1 conjugation to STAT1. Blood (2003) 1.29
IL-17A induces eotaxin-1/CC chemokine ligand 11 expression in human airway smooth muscle cells: role of MAPK (Erk1/2, JNK, and p38) pathways. J Immunol (2006) 1.29
Fully human monoclonal antibodies antagonizing the glucagon receptor improve glucose homeostasis in mice and monkeys. J Pharmacol Exp Ther (2009) 1.29
Substrate specificity of the macrolide-glycosylating enzyme pair DesVII/DesVIII: opportunities, limitations, and mechanistic hypotheses. Angew Chem Int Ed Engl (2006) 1.27
Prognostic value of K-RAS mutations in patients with non-small cell lung cancer: a systematic review with meta-analysis. Lung Cancer (2013) 1.24
Diagnostic validity (or acuity) of 2D CCD versus 3D CBCT-images for assessing periodontal breakdown. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2007) 1.24
Efficiency of anthropometric indicators of obesity for identifying cardiovascular risk factors in a Chinese population. Postgrad Med J (2011) 1.24
Redox sensing by proteins: oxidative modifications on cysteines and the consequent events. Antioxid Redox Signal (2011) 1.24
Frenolicins C-G, pyranonaphthoquinones from Streptomyces sp. RM-4-15. J Nat Prod (2013) 1.23
Long-term inhibition of the glucagon receptor with a monoclonal antibody in mice causes sustained improvement in glycemic control, with reversible alpha-cell hyperplasia and hyperglucagonemia. J Pharmacol Exp Ther (2009) 1.22
The impact of enzyme engineering upon natural product glycodiversification. Curr Opin Chem Biol (2008) 1.22
Model for antibiotic optimization via neoglycosylation: synthesis of liponeoglycopeptides active against VRE. J Am Chem Soc (2007) 1.19
Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering. Proc Natl Acad Sci U S A (2002) 1.19
Green tea drinking, high tea temperature and esophageal cancer in high- and low-risk areas of Jiangsu Province, China: a population-based case-control study. Int J Cancer (2009) 1.19
Radiomorphometric indices and their relation to gender, age, and dental status. Oral Surg Oral Med Oral Pathol Oral Radiol Endod (2005) 1.19
NK T cell activation promotes Chlamydia trachomatis infection in vivo. J Immunol (2005) 1.18
Weighted-support vector machines for predicting membrane protein types based on pseudo-amino acid composition. Protein Eng Des Sel (2004) 1.18
Neoglycorandomization and chemoenzymatic glycorandomization: two complementary tools for natural product diversification. J Nat Prod (2005) 1.18
The biosynthetic genes encoding for the production of the dynemicin enediyne core in Micromonospora chersina ATCC53710. FEMS Microbiol Lett (2008) 1.17
Colchicine glycorandomization influences cytotoxicity and mechanism of action. J Am Chem Soc (2006) 1.17
Herbimycins D-F, ansamycin analogues from Streptomyces sp. RM-7-15. J Nat Prod (2013) 1.17
Berberine inhibits human hepatoma cell invasion without cytotoxicity in healthy hepatocytes. PLoS One (2011) 1.16
A subset of gastric cancers with EGFR amplification and overexpression respond to cetuximab therapy. Sci Rep (2013) 1.16
Degree prediction of malignancy in brain glioma using support vector machines. Comput Biol Med (2006) 1.16
Effects of raf kinase inhibitor protein expression on metastasis and progression of human breast cancer. Mol Cancer Res (2009) 1.15
Using simple donors to drive the equilibria of glycosyltransferase-catalyzed reactions. Nat Chem Biol (2011) 1.15
Deciphering indolocarbazole and enediyne aminodideoxypentose biosynthesis through comparative genomics: insights from the AT2433 biosynthetic locus. Chem Biol (2006) 1.15
Regulation of autophagy and ubiquitinated protein accumulation by bFGF promotes functional recovery and neural protection in a rat model of spinal cord injury. Mol Neurobiol (2013) 1.15
Novel application of electrostatic repulsion-hydrophilic interaction chromatography (ERLIC) in shotgun proteomics: comprehensive profiling of rat kidney proteome. J Proteome Res (2010) 1.14
Structural basis for the regulation of protein kinase A by activation loop phosphorylation. J Biol Chem (2012) 1.14
Chinese "herbal" cigarettes are as carcinogenic and addictive as regular cigarettes. Cancer Epidemiol Biomarkers Prev (2009) 1.13
Polyketide synthase chemistry does not direct biosynthetic divergence between 9- and 10-membered enediynes. Proc Natl Acad Sci U S A (2010) 1.13
The glycosyltransferase UrdGT2 catalyzes both C- and O-glycosidic sugar transfers. Angew Chem Int Ed Engl (2004) 1.13
Probing the aglycon promiscuity of an engineered glycosyltransferase. Angew Chem Int Ed Engl (2008) 1.12
The structure of flavin-dependent tryptophan 7-halogenase RebH. Proteins (2008) 1.12
The in vitro characterization of the iterative avermectin glycosyltransferase AveBI reveals reaction reversibility and sugar nucleotide flexibility. J Am Chem Soc (2006) 1.12
Structure and mechanism of the rebeccamycin sugar 4'-O-methyltransferase RebM. J Biol Chem (2008) 1.12
Surgical treatment of primary palmar hyperhidrosis: a prospective randomized study comparing T3 and T4 sympathicotomy. Eur J Cardiothorac Surg (2009) 1.11
Durable complete clinical responses in a phase I/II trial using an autologous melanoma cell/dendritic cell vaccine. Cancer Immunol Immunother (2003) 1.11
A novel far-red bimolecular fluorescence complementation system that allows for efficient visualization of protein interactions under physiological conditions. Biosens Bioelectron (2009) 1.11
Crystal structure of the E230Q mutant of cAMP-dependent protein kinase reveals an unexpected apoenzyme conformation and an extended N-terminal A helix. Protein Sci (2005) 1.11
Differential expression of survivin-2B and survivin-DeltaEx3 is inversely associated with disease relapse and patient survival in non-small-cell lung cancer (NSCLC). Lung Cancer (2005) 1.10
Natural product diversification using a non-natural cofactor analogue of S-adenosyl-L-methionine. J Am Chem Soc (2006) 1.10
The results of transperineal versus transrectal prostate biopsy: a systematic review and meta-analysis. Asian J Androl (2011) 1.09
Antiangiogenic and antitumor agents. Design, synthesis, and evaluation of novel 2-amino-4-(3-bromoanilino)-6-benzylsubstituted pyrrolo[2,3-d]pyrimidines as inhibitors of receptor tyrosine kinases. Bioorg Med Chem (2003) 1.09
miREnvironment database: providing a bridge for microRNAs, environmental factors and phenotypes. Bioinformatics (2011) 1.08
SLLE for predicting membrane protein types. J Theor Biol (2005) 1.08