Published in J Immunol on August 01, 2007
Membrane vesicles as conveyors of immune responses. Nat Rev Immunol (2009) 14.72
Extracellular vesicles: exosomes, microvesicles, and friends. J Cell Biol (2013) 10.02
Membrane vesicles, current state-of-the-art: emerging role of extracellular vesicles. Cell Mol Life Sci (2011) 5.42
Standardization of sample collection, isolation and analysis methods in extracellular vesicle research. J Extracell Vesicles (2013) 4.05
Selective release of microRNA species from normal and malignant mammary epithelial cells. PLoS One (2010) 3.50
ExoCarta 2012: database of exosomal proteins, RNA and lipids. Nucleic Acids Res (2011) 3.28
Regulation of immune responses by extracellular vesicles. Nat Rev Immunol (2014) 3.24
Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation. PLoS Biol (2012) 3.18
Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. J Transl Med (2011) 3.03
Biological properties of extracellular vesicles and their physiological functions. J Extracell Vesicles (2015) 3.02
Exosomes: immune properties and potential clinical implementations. Semin Immunopathol (2010) 2.60
microRNA as a new immune-regulatory agent in breast milk. Silence (2010) 2.20
Isolation and characterization of RNA-containing exosomes. J Vis Exp (2012) 2.16
Immune-related microRNAs are abundant in breast milk exosomes. Int J Biol Sci (2011) 2.11
Nanostructural and transcriptomic analyses of human saliva derived exosomes. PLoS One (2010) 2.11
Microvesicles and viral infection. J Virol (2011) 2.10
Flow cytometric analysis of circulating microparticles in plasma. Cytometry A (2010) 2.09
Proteomics analysis of A33 immunoaffinity-purified exosomes released from the human colon tumor cell line LIM1215 reveals a tissue-specific protein signature. Mol Cell Proteomics (2009) 2.08
Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense. FASEB J (2009) 2.07
Proteomics analysis of bladder cancer exosomes. Mol Cell Proteomics (2010) 2.04
Exosomes communicate protective messages during oxidative stress; possible role of exosomal shuttle RNA. PLoS One (2010) 1.94
Exosomes/microvesicles: mediators of cancer-associated immunosuppressive microenvironments. Semin Immunopathol (2011) 1.93
Intercellular communication by exosome-derived microRNAs in cancer. Int J Mol Sci (2013) 1.81
Tumor-derived microvesicles promote regulatory T cell expansion and induce apoptosis in tumor-reactive activated CD8+ T lymphocytes. J Immunol (2009) 1.79
Altered microRNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients. J Allergy Clin Immunol (2013) 1.79
Thymus exosomes-like particles induce regulatory T cells. J Immunol (2008) 1.73
Fluorescent labeling of nano-sized vesicles released by cells and subsequent quantitative and qualitative analysis by high-resolution flow cytometry. Nat Protoc (2012) 1.71
Induction of plasma (TRAIL), TNFR-2, Fas ligand, and plasma microparticles after human immunodeficiency virus type 1 (HIV-1) transmission: implications for HIV-1 vaccine design. J Virol (2008) 1.69
Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells. PLoS One (2012) 1.67
Exosomes released by islet-derived mesenchymal stem cells trigger autoimmune responses in NOD mice. Diabetes (2013) 1.62
Tetraspanins in extracellular vesicle formation and function. Front Immunol (2014) 1.56
Characterization of mRNA and microRNA in human mast cell-derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells. J Extracell Vesicles (2012) 1.52
Exosomes as intercellular signaling organelles involved in health and disease: basic science and clinical applications. Int J Mol Sci (2013) 1.50
MicroRNAs are exported from malignant cells in customized particles. Nucleic Acids Res (2012) 1.43
Ineffective delivery of diet-derived microRNAs to recipient animal organisms. RNA Biol (2013) 1.41
Role of pancreatic cancer-derived exosomes in salivary biomarker development. J Biol Chem (2013) 1.37
Proteomic analysis of urine exosomes by multidimensional protein identification technology (MudPIT). Proteomics (2011) 1.31
Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Mol Cell Proteomics (2012) 1.26
Lactation-related microRNA expression profiles of porcine breast milk exosomes. PLoS One (2012) 1.24
Recovery of extracellular vesicles from human breast milk is influenced by sample collection and vesicle isolation procedures. J Extracell Vesicles (2014) 1.23
Immature, Semi-Mature, and Fully Mature Dendritic Cells: Toward a DC-Cancer Cells Interface That Augments Anticancer Immunity. Front Immunol (2013) 1.22
Molecular characterization of exosome-like vesicles from breast cancer cells. BMC Cancer (2014) 1.11
C. elegans ciliated sensory neurons release extracellular vesicles that function in animal communication. Curr Biol (2014) 1.11
Extracellular vesicles including exosomes are mediators of signal transduction: are they protective or pathogenic? Proteomics (2014) 1.09
Exosomes isolated from mycobacteria-infected mice or cultured macrophages can recruit and activate immune cells in vitro and in vivo. J Immunol (2012) 1.09
Proteomics analysis of cancer exosomes using a novel modified aptamer-based array (SOMAscan™) platform. Mol Cell Proteomics (2014) 1.08
Altered microRNA expression profile in exosomes during osteogenic differentiation of human bone marrow-derived mesenchymal stem cells. PLoS One (2014) 1.07
Antigen-specific, antibody-coated, exosome-like nanovesicles deliver suppressor T-cell microRNA-150 to effector T cells to inhibit contact sensitivity. J Allergy Clin Immunol (2013) 1.04
Systemically circulating viral and tumor-derived microRNAs in KSHV-associated malignancies. PLoS Pathog (2013) 1.04
A test of current models for the mechanism of milk-lipid droplet secretion. Traffic (2013) 1.03
Extracellular vesicles: potential applications in cancer diagnosis, prognosis, and epidemiology. BMC Clin Pathol (2015) 1.02
Nanovesicles from Malassezia sympodialis and host exosomes induce cytokine responses--novel mechanisms for host-microbe interactions in atopic eczema. PLoS One (2011) 1.02
"Small Talk" in the Innate Immune System via RNA-Containing Extracellular Vesicles. Front Immunol (2014) 1.01
Exploration of microRNAs in porcine milk exosomes. BMC Genomics (2014) 1.01
Cellular phenotype and extracellular vesicles: basic and clinical considerations. Stem Cells Dev (2014) 1.00
Tumor-derived exosomes: A message delivery system for tumor progression. Commun Integr Biol (2014) 0.99
Exosomes from red blood cell units bind to monocytes and induce proinflammatory cytokines, boosting T-cell responses in vitro. Blood (2013) 0.98
Different types of in vitro generated human monocyte-derived dendritic cells release exosomes with distinct phenotypes. Immunology (2007) 0.98
Highly skewed distribution of miRNAs and proteins between colorectal cancer cells and their exosomes following Cetuximab treatment: biomolecular, genetic and translational implications. Oncoscience (2014) 0.97
Immune modulatory function of abundant immune-related microRNAs in microvesicles from bovine colostrum. Protein Cell (2013) 0.97
The PRY/SPRY/B30.2 domain of butyrophilin 1A1 (BTN1A1) binds to xanthine oxidoreductase: implications for the function of BTN1A1 in the mammary gland and other tissues. J Biol Chem (2009) 0.97
Exosomal miRNAs as potential biomarkers of cardiovascular risk in children. J Transl Med (2014) 0.96
Exosomes and Their Role in the Life Cycle and Pathogenesis of RNA Viruses. Viruses (2015) 0.95
Monocyte exosomes stimulate the osteogenic gene expression of mesenchymal stem cells. PLoS One (2013) 0.94
Immunotherapeutic potential of extracellular vesicles. Front Immunol (2014) 0.94
Immunomodulatory role of microRNAs transferred by extracellular vesicles. Biol Cell (2015) 0.94
Milk: an exosomal microRNA transmitter promoting thymic regulatory T cell maturation preventing the development of atopy? J Transl Med (2014) 0.94
Tumor-derived exosomes in cancer progression and treatment failure. Oncotarget (2015) 0.94
Plasma-derived MHC class II+ exosomes from tumor-bearing mice suppress tumor antigen-specific immune responses. Eur J Immunol (2012) 0.93
Bovine milk-derived exosomes for drug delivery. Cancer Lett (2015) 0.93
Activated human T cells secrete exosomes that participate in IL-2 mediated immune response signaling. PLoS One (2012) 0.93
Exosomes derived from Burkitt's lymphoma cell lines induce proliferation, differentiation, and class-switch recombination in B cells. J Immunol (2014) 0.92
Commercial cow milk contains physically stable extracellular vesicles expressing immunoregulatory TGF-β. PLoS One (2015) 0.90
Differential temporal expression of milk miRNA during the lactation cycle of the marsupial tammar wallaby (Macropus eugenii). BMC Genomics (2014) 0.89
Investigation of soluble and transmembrane CTLA-4 isoforms in serum and microvesicles. J Immunol (2014) 0.89
Human semen contains exosomes with potent anti-HIV-1 activity. Retrovirology (2014) 0.89
Time-dependent expression profiles of microRNAs and mRNAs in rat milk whey. PLoS One (2014) 0.89
Characterization of multiple myeloma vesicles by label-free relative quantitation. Proteomics (2013) 0.89
MicroRNAs in Breastmilk and the Lactating Breast: Potential Immunoprotectors and Developmental Regulators for the Infant and the Mother. Int J Environ Res Public Health (2015) 0.88
Mast cell exosomes promote lung adenocarcinoma cell proliferation - role of KIT-stem cell factor signaling. Cell Commun Signal (2014) 0.88
Exosomes: an overview of biogenesis, composition and role in ovarian cancer. J Ovarian Res (2014) 0.88
Exosomes: Implications in HIV-1 Pathogenesis. Viruses (2015) 0.87
The role of extracellular vesicles in phenotypic cancer transformation. Radiol Oncol (2013) 0.87
Mast cell synapses and exosomes: membrane contacts for information exchange. Front Immunol (2012) 0.86
MicroRNA expression profiles of bovine milk exosomes in response to Staphylococcus aureus infection. BMC Genomics (2015) 0.86
Using exosomes, naturally-equipped nanocarriers, for drug delivery. J Control Release (2015) 0.86
Exosomal Proteome Profiling: A Potential Multi-Marker Cellular Phenotyping Tool to Characterize Hypoxia-Induced Radiation Resistance in Breast Cancer. Proteomes (2013) 0.86
Proteomics and pathway analyses of the milk fat globule in sheep naturally infected by Mycoplasma agalactiae provide indications of the in vivo response of the mammary epithelium to bacterial infection. Infect Immun (2011) 0.85
Human aqueous humor exosomes. Exp Eye Res (2015) 0.85
Proteomics of microparticles with SILAC Quantification (PROMIS-Quan): a novel proteomic method for plasma biomarker quantification. Mol Cell Proteomics (2015) 0.84
Butyrophilin Btn2a2 inhibits TCR activation and phosphatidylinositol 3-kinase/Akt pathway signaling and induces Foxp3 expression in T lymphocytes. J Immunol (2013) 0.84
The potential mechanistic link between allergy and obesity development and infant formula feeding. Allergy Asthma Clin Immunol (2014) 0.84
Proteomics of ovarian cancer: functional insights and clinical applications. Cancer Metastasis Rev (2015) 0.84
Human Milk MicroRNA and Total RNA Differ Depending on Milk Fractionation. J Cell Biochem (2015) 0.83
MicroRNA in exosomes isolated directly from the liver circulation in patients with metastatic uveal melanoma. BMC Cancer (2014) 0.83
Exosomes confer pro-survival signals to alter the phenotype of prostate cells in their surrounding environment. Oncotarget (2016) 0.82
Immunosuppressive exosomes: a new approach for treating arthritis. Int J Rheumatol (2012) 0.82
Regulation of chronic inflammatory and immune processes by extracellular vesicles. J Clin Invest (2016) 0.82
Copy number variation and selection during reprogramming to pluripotency. Nature (2011) 8.24
Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells. Cell Stem Cell (2011) 7.41
Epigenome-wide association data implicate DNA methylation as an intermediary of genetic risk in rheumatoid arthritis. Nat Biotechnol (2013) 5.89
Differential DNA methylation in purified human blood cells: implications for cell lineage and studies on disease susceptibility. PLoS One (2012) 5.03
MicroRNAs: novel regulators involved in the pathogenesis of psoriasis? PLoS One (2007) 3.96
One-year survival of extremely preterm infants after active perinatal care in Sweden. JAMA (2009) 3.29
High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity. Nat Biotechnol (2010) 3.21
Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation. PLoS Biol (2012) 3.18
A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition. Nat Cell Biol (2009) 3.12
Cesarean section and development of the immune system in the offspring. Am J Obstet Gynecol (2012) 3.05
Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. J Transl Med (2011) 3.03
Timing of pharmacological treatment for patent ductus arteriosus and risk of secondary surgery, death or bronchopulmonary dysplasia: a population-based cohort study of extremely preterm infants. Neonatology (2014) 2.80
Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes. J Exp Med (2008) 2.79
A practical comparison of methods for detecting transcription factor binding sites in ChIP-seq experiments. BMC Genomics (2009) 2.70
Allergic disease and sensitization in Steiner school children. J Allergy Clin Immunol (2005) 2.44
Obstetric and perinatal outcomes in type 1 diabetic pregnancies: A large, population-based study. Diabetes Care (2009) 2.26
Genomic views of STAT function in CD4+ T helper cell differentiation. Nat Rev Immunol (2011) 2.09
Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report. J Allergy Clin Immunol (2006) 2.00
Proinflammatory exosomes in bronchoalveolar lavage fluid of patients with sarcoidosis. Thorax (2010) 1.92
Gene expression profiling during differentiation of human monocytes to macrophages or dendritic cells. J Leukoc Biol (2007) 1.90
Difference in gene expression between human fetal liver and adult bone marrow mesenchymal stem cells. Haematologica (2005) 1.90
Perinatal risk factors for ischemic heart disease: disentangling the roles of birth weight and preterm birth. Circulation (2008) 1.87
Gene expression signatures of seven individual human embryonic stem cell lines. Stem Cells (2005) 1.86
Prenatal farm exposure is related to the expression of receptors of the innate immunity and to atopic sensitization in school-age children. J Allergy Clin Immunol (2006) 1.84
Altered microRNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients. J Allergy Clin Immunol (2013) 1.79
Haplotypes of G protein-coupled receptor 154 are associated with childhood allergy and asthma. Am J Respir Crit Care Med (2005) 1.78
IgE-mediated and T cell-mediated autoimmunity against manganese superoxide dismutase in atopic dermatitis. J Allergy Clin Immunol (2005) 1.74
Microarrayed allergen molecules: diagnostic gatekeepers for allergy treatment. FASEB J (2002) 1.66
Timing of infant feeding in relation to childhood asthma and allergic diseases. J Allergy Clin Immunol (2012) 1.62
Systematic construction of gene coexpression networks with applications to human T helper cell differentiation process. Bioinformatics (2007) 1.54
Constitutively active cytoplasmic c-Jun N-terminal kinase 1 is a dominant regulator of dendritic architecture: role of microtubule-associated protein 2 as an effector. J Neurosci (2005) 1.54
Class A scavenger receptors regulate tolerance against apoptotic cells, and autoantibodies against these receptors are predictive of systemic lupus. J Exp Med (2007) 1.53
The importance of an endotoxin-free environment during the production of nanoparticles used in medical applications. Nano Lett (2006) 1.52
Endothelial function in newborn infants is related to folate levels and birth weight. Pediatrics (2007) 1.50
Low salivary cortisol levels in infants of families with an anthroposophic lifestyle. Psychoneuroendocrinology (2010) 1.48
Toxicology of engineered nanomaterials: focus on biocompatibility, biodistribution and biodegradation. Biochim Biophys Acta (2010) 1.48
Neurodevelopmental outcome in extremely preterm infants at 2.5 years after active perinatal care in Sweden. JAMA (2013) 1.47
Hypertension, diabetes and overweight: looming legacies of the Biafran famine. PLoS One (2010) 1.44
Integrating probe-level expression changes across generations of Affymetrix arrays. Nucleic Acids Res (2005) 1.42
Direct exosome stimulation of peripheral human T cells detected by ELISPOT. Eur J Immunol (2006) 1.40
The glycoprotein cytoplasmic tail of Uukuniemi virus (Bunyaviridae) interacts with ribonucleoproteins and is critical for genome packaging. J Virol (2007) 1.39
Genetic and epigenetic stability of human pluripotent stem cells. Nat Rev Genet (2012) 1.38
Perinatal risk factors for diabetes in later life. Diabetes (2008) 1.36
Expression and regulation of the pattern recognition receptors Toll-like receptor-2 and Toll-like receptor-4 in the human placenta. Immunology (2002) 1.33
Inflammatory mediators expressed in human islets of Langerhans: implications for islet transplantation. Biochem Biophys Res Commun (2003) 1.33
Measurement of interleukin 8 in combination with C-reactive protein reduced unnecessary antibiotic therapy in newborn infants: a multicenter, randomized, controlled trial. Pediatrics (2004) 1.31
Early target genes of IL-12 and STAT4 signaling in th cells. J Immunol (2004) 1.31
Genome-wide profiling of interleukin-4 and STAT6 transcription factor regulation of human Th2 cell programming. Immunity (2010) 1.28
Global chromatin state analysis reveals lineage-specific enhancers during the initiation of human T helper 1 and T helper 2 cell polarization. Immunity (2013) 1.27
Malassezia fungi are specialized to live on skin and associated with dandruff, eczema, and other skin diseases. PLoS Pathog (2012) 1.24
Exosomes containing glycoprotein 350 released by EBV-transformed B cells selectively target B cells through CD21 and block EBV infection in vitro. J Immunol (2010) 1.24
Antigen-loaded exosomes alone induce Th1-type memory through a B-cell-dependent mechanism. Blood (2009) 1.23
Molecular fingerprinting of the fecal microbiota of children raised according to different lifestyles. Appl Environ Microbiol (2007) 1.23
Risk of high blood pressure among young men increases with the degree of immaturity at birth. Circulation (2005) 1.22
Genome-wide identification of novel genes involved in early Th1 and Th2 cell differentiation. J Immunol (2007) 1.21
Folate, vitamin B12, and homocysteine levels in South Asian women with growth-retarded fetuses. Acta Obstet Gynecol Scand (2005) 1.20
Identification of novel IL-4/Stat6-regulated genes in T lymphocytes. J Immunol (2003) 1.20
Generation and analysis of infectious virus-like particles of uukuniemi virus (bunyaviridae): a useful system for studying bunyaviral packaging and budding. J Virol (2006) 1.19
Mesoporous silica particles induce size dependent effects on human dendritic cells. Nano Lett (2007) 1.18
Phosphatidylserine targets single-walled carbon nanotubes to professional phagocytes in vitro and in vivo. PLoS One (2009) 1.16
Vacuum assisted birth and risk for cerebral complications in term newborn infants: a population-based cohort study. BMC Pregnancy Childbirth (2014) 1.16
Efficient internalization of silica-coated iron oxide nanoparticles of different sizes by primary human macrophages and dendritic cells. Toxicol Appl Pharmacol (2011) 1.16
Differential expression of IFN regulatory factor 4 gene in human monocyte-derived dendritic cells and macrophages. J Immunol (2005) 1.15
Genomic insights into the atopic eczema-associated skin commensal yeast Malassezia sympodialis. MBio (2013) 1.15
Preterm birth contributes to increased vascular resistance and higher blood pressure in adolescent girls. Pediatr Res (2005) 1.14
Biological and genetic interaction between tenascin C and neuropeptide S receptor 1 in allergic diseases. Hum Mol Genet (2008) 1.14
Dendritic cell-derived exosomes need to activate both T and B cells to induce antitumor immunity. J Immunol (2013) 1.14
Identification of genes involved in the initiation of human Th1 or Th2 cell commitment. Eur J Immunol (2005) 1.12
Natural killer and dendritic cell contact in lesional atopic dermatitis skin--Malassezia-influenced cell interaction. J Invest Dermatol (2002) 1.12
Probe-level estimation improves the detection of differential splicing in Affymetrix exon array studies. Genome Biol (2009) 1.10
Association analysis of common variants of STAT6, GATA3, and STAT4 to asthma and high serum IgE phenotypes. J Allergy Clin Immunol (2005) 1.08
PARP-14, a member of the B aggressive lymphoma family, transduces survival signals in primary B cells. Blood (2009) 1.08
Exosomes from human macrophages and dendritic cells contain enzymes for leukotriene biosynthesis and promote granulocyte migration. J Allergy Clin Immunol (2010) 1.07
The cytoplasmic tails of Uukuniemi Virus (Bunyaviridae) G(N) and G(C) glycoproteins are important for intracellular targeting and the budding of virus-like particles. J Virol (2007) 1.07
Global expression profiling in atopic eczema reveals reciprocal expression of inflammatory and lipid genes. PLoS One (2008) 1.06
Th1 response and cytotoxicity genes are down-regulated in cutaneous T-cell lymphoma. Clin Cancer Res (2006) 1.05
B cell-derived exosomes can present allergen peptides and activate allergen-specific T cells to proliferate and produce TH2-like cytokines. J Allergy Clin Immunol (2007) 1.05
Early hyperglycemia is a risk factor for death and white matter reduction in preterm infants. Pediatrics (2010) 1.04
Nanovesicles from Malassezia sympodialis and host exosomes induce cytokine responses--novel mechanisms for host-microbe interactions in atopic eczema. PLoS One (2011) 1.02
Identification of novel genes regulated by IL-12, IL-4, or TGF-beta during the early polarization of CD4+ lymphocytes. J Immunol (2003) 1.02
High blood pressure in 2.5-year-old children born extremely preterm. Pediatrics (2012) 1.02
Gene expression profiling of immune-competent human cells exposed to engineered zinc oxide or titanium dioxide nanoparticles. PLoS One (2013) 1.02
Capturing cell-fate decisions from the molecular signatures of a receptor-dependent signaling response. Mol Syst Biol (2007) 1.02
The prevalence of Malassezia yeasts in patients with atopic dermatitis, seborrhoeic dermatitis and healthy controls. Acta Derm Venereol (2005) 1.02
Four permeases import proline and the toxic proline analogue azetidine-2-carboxylate into yeast. Yeast (2004) 1.01
Autoimmune regulator induced changes in the gene expression profile of human monocyte-dendritic cell-lineage. Mol Immunol (2004) 1.01
RNA-binding protein L1TD1 interacts with LIN28 via RNA and is required for human embryonic stem cell self-renewal and cancer cell proliferation. Stem Cells (2012) 1.01