Published in Eur J Biochem on December 18, 1991
Studies on anticancer activities of antimicrobial peptides. Biochim Biophys Acta (2007) 3.24
Protegrin-1: a broad-spectrum, rapidly microbicidal peptide with in vivo activity. Antimicrob Agents Chemother (1997) 3.12
Structure and organization of the human antimicrobial peptide LL-37 in phospholipid membranes: relevance to the molecular basis for its non-cell-selective activity. Biochem J (1999) 2.93
FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis. Proc Natl Acad Sci U S A (1995) 2.89
The porcine lung as a potential model for cystic fibrosis. Am J Physiol Lung Cell Mol Physiol (2008) 2.53
Mechanisms of action on Escherichia coli of cecropin P1 and PR-39, two antibacterial peptides from pig intestine. Infect Immun (1993) 2.37
Syndecans, cell surface heparan sulfate proteoglycans, are induced by a proline-rich antimicrobial peptide from wounds. Proc Natl Acad Sci U S A (1994) 2.02
Squalamine: an aminosterol antibiotic from the shark. Proc Natl Acad Sci U S A (1993) 1.67
Enteric beta-defensin: molecular cloning and characterization of a gene with inducible intestinal epithelial cell expression associated with Cryptosporidium parvum infection. Infect Immun (1998) 1.48
Improved activity of a synthetic indolicidin analog. Antimicrob Agents Chemother (1997) 1.41
Antibacterial activity within degradation products of biological scaffolds composed of extracellular matrix. Tissue Eng (2006) 1.40
Novel antimicrobial peptides derived from human immunodeficiency virus type 1 and other lentivirus transmembrane proteins. Antimicrob Agents Chemother (1997) 1.35
Structure, membrane orientation, mechanism, and function of pexiganan--a highly potent antimicrobial peptide designed from magainin. Biochim Biophys Acta (2008) 1.31
Inhibition of ubiquitin-proteasome pathway-mediated I kappa B alpha degradation by a naturally occurring antibacterial peptide. J Clin Invest (2000) 1.27
Structure of the gene for porcine peptide antibiotic PR-39, a cathelin gene family member: comparative mapping of the locus for the human peptide antibiotic FALL-39. Proc Natl Acad Sci U S A (1995) 1.26
Expression of an additional cathelicidin antimicrobial peptide protects against bacterial skin infection. Proc Natl Acad Sci U S A (2005) 1.26
Antimicrobial peptides in the gastrointestinal tract. Gut (1997) 1.21
Mechanism and fitness costs of PR-39 resistance in Salmonella enterica serovar Typhimurium LT2. Antimicrob Agents Chemother (2008) 1.16
Antibacterial activity of a synthetic peptide (PR-26) derived from PR-39, a proline-arginine-rich neutrophil antimicrobial peptide. Antimicrob Agents Chemother (1996) 1.09
PR-39, a proline-rich antibacterial peptide that inhibits phagocyte NADPH oxidase activity by binding to Src homology 3 domains of p47 phox. Proc Natl Acad Sci U S A (1996) 1.07
Regulation of cathelicidin gene expression: induction by lipopolysaccharide, interleukin-6, retinoic acid, and Salmonella enterica serovar typhimurium infection. Infect Immun (2000) 1.05
Acylation of SC4 dodecapeptide increases bactericidal potency against Gram-positive bacteria, including drug-resistant strains. Biochem J (2004) 1.04
Highly selective end-tagged antimicrobial peptides derived from PRELP. PLoS One (2011) 1.02
Structure-function relationships in novel peptide dodecamerswith broad-spectrum bactericidal and endotoxin-neutralizing activities. Biochem J (2000) 0.96
Molecular basis for proline- and arginine-rich peptide inhibition of proteasome. J Mol Biol (2008) 0.92
Proline-rich antimicrobial peptide, PR-39 gene transduction altered invasive activity and actin structure in human hepatocellular carcinoma cells. Br J Cancer (1999) 0.91
RL-37, an alpha-helical antimicrobial peptide of the rhesus monkey. Antimicrob Agents Chemother (2001) 0.91
Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition. Nucleic Acids Res (2016) 0.91
Topomimetics of amphipathic beta-sheet and helix-forming bactericidal peptides neutralize lipopolysaccharide endotoxins. J Med Chem (2006) 0.90
Antimicrobial peptides and induced membrane curvature: geometry, coordination chemistry, and molecular engineering. Curr Opin Solid State Mater Sci (2013) 0.89
Heparan sulfate proteoglycan-dependent neutrophil chemotaxis toward PR-39 cathelicidin. J Inflamm (Lond) (2006) 0.88
Structure-activity relationships of the antimicrobial peptide arasin 1 - and mode of action studies of the N-terminal, proline-rich region. PLoS One (2013) 0.87
Identification of a novel antimicrobial peptide from human hepatitis B virus core protein arginine-rich domain (ARD). PLoS Pathog (2013) 0.87
Cathelicidin gene expression in porcine tissues: roles in ontogeny and tissue specificity. Infect Immun (1999) 0.83
Expression and activity of a novel cathelicidin from domestic cats. PLoS One (2011) 0.82
Highly potent antimicrobial peptides from N-terminal membrane-binding region of E. coli MreB. Sci Rep (2017) 0.79
Antimicrobial and immunomodulatory activities of PR-39 derived peptides. PLoS One (2014) 0.78
PR-39, a porcine host defence peptide, is prominent in mucosa and lymphatic tissue of the respiratory tract in healthy pigs and pigs infected with Actinobacillus pleuropneumoniae. BMC Res Notes (2012) 0.78
Interspecies cathelicidin comparison reveals divergence in antimicrobial activity, TLR modulation, chemokine induction and regulation of phagocytosis. Sci Rep (2017) 0.77
Towards a paradigm shift in innate immunity-seminal work by Hans G. Boman and co-workers. Philos Trans R Soc Lond B Biol Sci (2016) 0.76
Attacin gene sequence variations in different ecoraces of tasar silkworm Antheraea mylitta. Bioinformation (2015) 0.75
Activity of AMP2041 against human and animal multidrug resistant Pseudomonas aeruginosa clinical isolates. Ann Clin Microbiol Antimicrob (2017) 0.75
Intracellular Targeting Mechanisms by Antimicrobial Peptides. Antimicrob Agents Chemother (2017) 0.75
Minibactenecins ChBac7.Nα and ChBac7. Nβ - Antimicrobial Peptides from Leukocytes of the Goat Capra hircus. Acta Naturae (2016) 0.75
Antimicrobial peptide exposure selects for Staphylococcus aureus resistance to human defence peptides. J Antimicrob Chemother (2016) 0.75
What can machine learning do for antimicrobial peptides, and what can antimicrobial peptides do for machine learning? Interface Focus (2017) 0.75
Cathelicidins Inhibit Escherichia coli-Induced TLR2 and TLR4 Activation in a Viability-Dependent Manner. J Immunol (2017) 0.75
Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme. J Biol Chem (1989) 11.06
Molecular basis of agonism and antagonism in the oestrogen receptor. Nature (1997) 9.09
Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry. Nat Med (1998) 8.62
Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties. Proc Natl Acad Sci U S A (1985) 6.20
Sequence and specificity of two antibacterial proteins involved in insect immunity. Nature (1981) 5.66
Sequence determinants of cytosolic N-terminal protein processing. Eur J Biochem (1986) 5.59
Notch1 expression in early lymphopoiesis influences B versus T lineage determination. Immunity (1999) 5.34
The cytotoxic protein YopE of Yersinia obstructs the primary host defence. Mol Microbiol (1990) 5.09
Insect immunity. Purification and properties of three inducible bactericidal proteins from hemolymph of immunized pupae of Hyalophora cecropia. Eur J Biochem (1980) 4.35
Resistance of Escherichia coli to penicillins. VI. Purification and characterization of the chromosomally mediated penicillinase present in ampA-containing strains. J Bacteriol (1970) 4.34
Polypeptide with broad biological activity: isolation from small intestine. Science (1970) 4.14
Neuropeptide Y--a novel brain peptide with structural similarities to peptide YY and pancreatic polypeptide. Nature (1982) 4.06
All-D amino acid-containing channel-forming antibiotic peptides. Proc Natl Acad Sci U S A (1990) 4.00
Modulation of virulence factor expression by pathogen target cell contact. Science (1996) 3.99
Characteristics of short-chain alcohol dehydrogenases and related enzymes. Eur J Biochem (1991) 3.67
Penicillin resistance in Escherichia coli K12: synergism between penicillinases and a barrier in the outer part of the envelope. Ann N Y Acad Sci (1974) 3.61
Mutant of Escherichia coli with anomalous cell division and ability to decrease episomally and chromosomally mediated resistance to ampicillin and several other antibiotics. J Bacteriol (1969) 3.54
Supplementation with folic acid during methotrexate therapy for rheumatoid arthritis. A double-blind, placebo-controlled trial. Ann Intern Med (1994) 3.53
Cell division in a chain-forming envA mutant of Escherichia coli K12. Fine structure of division sites and effects of EDTA, lysozyme and ampicillin. Acta Pathol Microbiol Scand B Microbiol Immunol (1971) 3.28
Immunocytochemical detection and mapping of a cytokeratin 18 neo-epitope exposed during early apoptosis. J Pathol (1999) 3.28
Insect immunity. Attacins, a family of antibacterial proteins from Hyalophora cecropia. EMBO J (1983) 3.27
Neuropeptide Y (NPY)-like immunoreactivity in peripheral noradrenergic neurons and effects of NPY on sympathetic function. Acta Physiol Scand (1982) 3.25
Patients with IgA nephropathy have increased serum galactose-deficient IgA1 levels. Kidney Int (2007) 3.17
Insect immunity: isolation and structure of cecropin D and four minor antibacterial components from Cecropia pupae. Eur J Biochem (1982) 3.17
Galanin - a novel biologically active peptide from porcine intestine. FEBS Lett (1983) 3.12
Ampicillin-resistant mutants of Escherichia coli K-12 with lipopolysaccharide alterations affecting mating ability and susceptibility to sex-specific bacteriophages. J Bacteriol (1971) 3.11
The human antimicrobial and chemotactic peptides LL-37 and alpha-defensins are expressed by specific lymphocyte and monocyte populations. Blood (2000) 3.09
The human gene FALL39 and processing of the cathelin precursor to the antibacterial peptide LL-37 in granulocytes. Eur J Biochem (1996) 3.08
Medium- and short-chain dehydrogenase/reductase gene and protein families : the SDR superfamily: functional and structural diversity within a family of metabolic and regulatory enzymes. Cell Mol Life Sci (2008) 3.07
FALL-39, a putative human peptide antibiotic, is cysteine-free and expressed in bone marrow and testis. Proc Natl Acad Sci U S A (1995) 2.89
Structure of the ligand-binding domain of oestrogen receptor beta in the presence of a partial agonist and a full antagonist. EMBO J (1999) 2.81
Resistance of Escherichia coli to Penicillins I. Genetic Study of Some Ampicillin-Resistant Mutants. J Bacteriol (1965) 2.81
Synthesis of the antibacterial peptide cecropin A (1-33). Biochemistry (1982) 2.78
Structure of porcine cholecystokinin-pancreozymin. 1. Cleavage with thrombin and with trypsin. Eur J Biochem (1968) 2.72
YopB and YopD constitute a novel class of Yersinia Yop proteins. Infect Immun (1993) 2.63
NIAID Mycoses Study Group Multicenter Trial of Oral Itraconazole Therapy for Invasive Aspergillosis. Am J Med (1994) 2.60
Inactivation of the Porphyromonas gingivalis fimA gene blocks periodontal damage in gnotobiotic rats. J Bacteriol (1994) 2.59
Antibacterial peptides from pig intestine: isolation of a mammalian cecropin. Proc Natl Acad Sci U S A (1989) 2.59
Isolation from porcine-intestinal wall of a vasoactive octacosapeptide related to secretin and to glucagon. Eur J Biochem (1972) 2.59
Insect pathogenic properties of Serratia marcescens: phage-resistant mutants with a decreased resistance to Cecropia immunity and a decreased virulence to Drosophila. J Gen Microbiol (1980) 2.49
Characterization of lipopolysaccharides from Escherichia coli K-12 mutants. J Bacteriol (1975) 2.48
Structure of porcine secretin. The amino acid sequence. Eur J Biochem (1970) 2.44
Antibodies against a synthetic peptide identify the Epstein-Barr virus-determined nuclear antigen. Proc Natl Acad Sci U S A (1984) 2.40
A randomized, double-blind trial of nystatin therapy for the candidiasis hypersensitivity syndrome. N Engl J Med (1990) 2.39
Aldehyde dehydrogenase from human liver. Primary structure of the cytoplasmic isoenzyme. Eur J Biochem (1984) 2.36
Isolation of two novel candidate hormones using a chemical method for finding naturally occurring polypeptides. Nature (1980) 2.31
The Drosophila RAD21 cohesin persists at the centromere region in mitosis. Curr Biol (2000) 2.29
Resistance of Escherichia coli to penicillins. V. Physiological comparison of two isogenic strains, one with chromosomally and one with episomally mediated ampicillin resistance. J Bacteriol (1968) 2.27
Intermediates in adenovirus assembly. J Virol (1976) 2.26
The impact of culture isolation of Aspergillus species: a hospital-based survey of aspergillosis. Clin Infect Dis (2001) 2.25
Male circumcision: a South Korean perspective. BJU Int (1999) 2.24
Structure of the IgG-binding regions of streptococcal protein G. EMBO J (1986) 2.20
Eye contact and face scanning in early infancy. Science (1977) 2.20
The clinical outcome of abdominoplasty performed under conscious sedation: increased use of fentanyl correlated with longer stay in outpatient unit. Plast Reconstr Surg (1999) 2.18
The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development. Genes Dev (2001) 2.17
Characteristics of alcohol/polyol dehydrogenases. The zinc-containing long-chain alcohol dehydrogenases. Eur J Biochem (1987) 2.17
Randomised clinical trial: the effects of Helicobacter pylori eradication on glandular atrophy and intestinal metaplasia after subtotal gastrectomy for gastric cancer. Aliment Pharmacol Ther (2013) 2.17
PD98059 is an equipotent antagonist of the aryl hydrocarbon receptor and inhibitor of mitogen-activated protein kinase kinase. Mol Pharmacol (1998) 2.16
Characterization of a gastrin releasing peptide from porcine non-antral gastric tissue. Biochem Biophys Res Commun (1979) 2.16
Cell-surface alterations in Escherichia coli K-12 with chromosmal mutations changing ampicillin resistance. Ann N Y Acad Sci (1971) 2.16
Prospective multicenter surveillance study of funguria in hospitalized patients. The National Institute for Allergy and Infectious Diseases (NIAID) Mycoses Study Group. Clin Infect Dis (2000) 2.15
Resistance of Escherichia coli to penicillins. IV. Genetic study of mutants resistant to D,L-ampicillin concentrations o 100 mu-g-ml. Genet Res (1968) 2.15
Resistance of Escherichia coli to penicillins. 3. AmpB, a locus affecting episomally and chromosomally mediated resistance to ampicillin and chlorampheincol. Genet Res (1968) 2.12
Pancreastatin, a novel pancreatic peptide that inhibits insulin secretion. Nature (1987) 2.09
Inducible antibacterial defence system in Drosophila. Nature (1972) 2.08
Rubella virus replication complexes are virus-modified lysosomes. Virology (1998) 2.07
CD44 is a major E-selectin ligand on human hematopoietic progenitor cells. J Cell Biol (2001) 2.07
Purification and biochemical characterization of the Epstein-Barr virus-determined nuclear antigen and an associated protein with a 53,000-dalton subunit. J Virol (1980) 2.07
Remodelling of nasal mucosa in mild and severe persistent allergic rhinitis with special reference to the distribution of collagen, proteoglycans, and lymphatic vessels. Clin Exp Allergy (2010) 2.04
N-terminally extended somatostatin: the primary structure of somatostatin-28. FEBS Lett (1980) 2.04
Structural analyses of mutant and wild-type alcohol dehydrogenases from drosophila melanogaster. Eur J Biochem (1976) 2.00
Dog saliva - an important source of dog allergens. Allergy (2013) 2.00
Vasoactive intestinal polypeptide in cholinergic neurons of exocrine glands: functional significance of coexisting transmitters for vasodilation and secretion. Proc Natl Acad Sci U S A (1980) 2.00
Localization of peptide YY (PYY) in gastrointestinal endocrine cells and effects on intestinal blood flow and motility. Proc Natl Acad Sci U S A (1982) 1.95
Acetylation of Protein N-terminal amino groups structural observations on alpha-amino acetylated proteins. J Theor Biol (1975) 1.93
Relationships of S-phase fraction of breast carcinoma in relapse to duration of remission, estrogen receptor content, therapeutic responsiveness, and duration of survival. Cancer Res (1980) 1.92
Structural insights into the mode of action of a pure antiestrogen. Structure (2001) 1.92
Re-evaluating the treatment of nongonococcal urethritis: emphasizing emerging pathogens--a randomized clinical trial. Clin Infect Dis (2011) 1.92
Structures of N-terminally acetylated proteins. Eur J Biochem (1985) 1.92
Specific binding of proinsulin C-peptide to human cell membranes. Proc Natl Acad Sci U S A (1999) 1.91
Cell-free immunity in Cecropia. A model system for antibacterial proteins. Eur J Biochem (1991) 1.90
Folic acid supplementation prevents deficient blood folate levels and hyperhomocysteinemia during longterm, low dose methotrexate therapy for rheumatoid arthritis: implications for cardiovascular disease prevention. J Rheumatol (1998) 1.88
In vitro induction of cecropin genes--an immune response in a Drosophila blood cell line. Biochem Biophys Res Commun (1992) 1.86
Molecular cloning, cDNA sequencing, and chemical synthesis of cecropin B from Hyalophora cecropia. Proc Natl Acad Sci U S A (1985) 1.85
Role for ceramide in cell cycle arrest. J Biol Chem (1995) 1.83
Aspirin use and bleeding risk after endoscopic submucosal dissection in patients with gastric neoplasms. Endoscopy (2012) 1.81
6,7-Bis(bromomethyl)-2,11,18,21,24-pentaoxatetracyclo. Acta Crystallogr C (2001) 1.79
Insect immunity. I. Characteristics of an inducible cell-free antibacterial reaction in hemolymph of Samia cynthia pupae. Infect Immun (1974) 1.78
Isolation and in vivo and in vitro antifungal activity of phenylacetic acid and sodium phenylacetate from Streptomyces humidus. Appl Environ Microbiol (2001) 1.77
Interaction of the mammalian antibacterial peptide cecropin P1 with phospholipid vesicles. Biochemistry (1995) 1.77
Somatic mutations in the kinase domain of the Met/hepatocyte growth factor receptor gene in childhood hepatocellular carcinomas. Cancer Res (1999) 1.74