Published in Psychoneuroendocrinology on July 30, 2007
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Nat Genet (2009) 14.86
A polymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels, and Alzheimer's disease risk. Cell (2008) 2.55
U-statistics-based tests for multiple genes in genetic association studies. Ann Hum Genet (2008) 1.53
Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease. Mol Psychiatry (2009) 1.51
Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease. Mol Psychiatry (2012) 1.20
The CALHM1 P86L polymorphism is a genetic modifier of age at onset in Alzheimer's disease: a meta-analysis study. J Alzheimers Dis (2010) 1.19
Structural and functional similarities of calcium homeostasis modulator 1 (CALHM1) ion channel with connexins, pannexins, and innexins. J Biol Chem (2013) 1.10
Genome wide association for addiction: replicated results and comparisons of two analytic approaches. PLoS One (2010) 1.04
Genomic regions identified by overlapping clusters of nominally-positive SNPs from genome-wide studies of alcohol and illegal substance dependence. PLoS One (2011) 1.00
Growth arrest-specific 1 binds to and controls the maturation and processing of the amyloid-beta precursor protein. Hum Mol Genet (2011) 0.94
CALHM1 P86L polymorphism modulates CSF Aβ levels in cognitively healthy individuals at risk for Alzheimer's disease. Mol Med (2011) 0.90
"Replicated" genome wide association for dependence on illegal substances: genomic regions identified by overlapping clusters of nominally positive SNPs. Am J Med Genet B Neuropsychiatr Genet (2010) 0.89
PIN1 gene variants in Alzheimer's disease. BMC Med Genet (2009) 0.86
Transgenic animal models of neurodegeneration based on human genetic studies. J Neural Transm (Vienna) (2010) 0.85
Total ApoE and ApoE4 isoform assays in an Alzheimer's disease case-control study by targeted mass spectrometry (n=669): a pilot assay for methionine-containing proteotypic peptides. Mol Cell Proteomics (2012) 0.82
Advances with RNA interference in Alzheimer's disease research. Drug Des Devel Ther (2013) 0.81
Neuropsychiatric Symptoms, Endophenotypes, and Syndromes in Late-Onset Alzheimer's Disease: Focus on APOE Gene. Int J Alzheimers Dis (2011) 0.81
Effect of the CALHM1 G330D and R154H human variants on the control of cytosolic Ca2+ and Aβ levels. PLoS One (2014) 0.80
Epigenetics of Alzheimer's disease and frontotemporal dementia. Neurotherapeutics (2013) 0.80
Study protocol: EXERcise and cognition in sedentary adults with early-ONset dementia (EXERCISE-ON). BMC Neurol (2012) 0.79
Gas1 interferes with AβPP trafficking by facilitating the accumulation of immature AβPP in endoplasmic reticulum-associated raft subdomains. J Alzheimers Dis (2012) 0.77
Searching for an endogenous anti-Alzheimer molecule: identifying small molecules in the brain that slow Alzheimer disease progression by inhibition of ß-amyloid aggregation. J Psychiatry Neurosci (2013) 0.75
Closing the gap between brain banks and proteomics to advance the study of neurodegenerative diseases. Proteomics Clin Appl (2015) 0.75
The algorithm for Alzheimer risk assessment based on APOE promoter polymorphisms. Alzheimers Res Ther (2016) 0.75
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Nat Genet (2009) 14.86
TREM2 variants in Alzheimer's disease. N Engl J Med (2012) 11.35
Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA (2010) 9.52
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet (2011) 9.23
Alpha-synuclein locus duplication as a cause of familial Parkinson's disease. Lancet (2004) 7.69
Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet (2012) 7.59
C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med (2012) 6.39
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet (2012) 4.63
Fruit and vegetable consumption and risk of coronary heart disease: a meta-analysis of cohort studies. J Nutr (2006) 4.63
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25
A polymorphism in CALHM1 influences Ca2+ homeostasis, Abeta levels, and Alzheimer's disease risk. Cell (2008) 2.55
Risk factors for coronary heart disease in patients treated for human immunodeficiency virus infection compared with the general population. Clin Infect Dis (2003) 2.54
Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium. Ann Neurol (2011) 2.37
Interleukin-18 and the risk of coronary heart disease in European men: the Prospective Epidemiological Study of Myocardial Infarction (PRIME). Circulation (2003) 2.26
Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population. Hum Mol Genet (2010) 2.21
Fruit and vegetable consumption and risk of stroke: a meta-analysis of cohort studies. Neurology (2005) 2.12
CYP2D6 polymorphism, pesticide exposure, and Parkinson's disease. Ann Neurol (2004) 2.03
Circulating soluble adhesion molecules ICAM-1 and VCAM-1 and incident coronary heart disease: the PRIME Study. Atherosclerosis (2003) 2.02
C-reactive protein, interleukin-6, and fibrinogen as predictors of coronary heart disease: the PRIME Study. Arterioscler Thromb Vasc Biol (2003) 1.99
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nat Genet (2012) 1.90
Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nat Genet (2012) 1.79
Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis. PLoS Genet (2011) 1.77
The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis. PLoS Med (2013) 1.70
Contribution of novel biomarkers to incident stable angina and acute coronary syndrome: the PRIME Study. Eur Heart J (2008) 1.68
Polymorphisms in the promoter regions of MMP-2, MMP-3, MMP-9 and MMP-12 genes as determinants of aneurysmal coronary artery disease. J Am Coll Cardiol (2002) 1.66
Implication of the immune system in Alzheimer's disease: evidence from genome-wide pathway analysis. J Alzheimers Dis (2010) 1.65
A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease. Circ Cardiovasc Genet (2011) 1.63
Household income is associated with the risk of metabolic syndrome in a sex-specific manner. Diabetes Care (2005) 1.59
Prognostic impact of matrix metalloproteinase gene polymorphisms in patients with heart failure according to the aetiology of left ventricular systolic dysfunction. Eur Heart J (2004) 1.59
Independent contribution of dairy products and calcium intake to blood pressure variations at a population level. J Hypertens (2006) 1.56
Fish consumption is associated with lower heart rates. Circulation (2003) 1.56
Single nucleotide polymorphisms in the FADS gene cluster are associated with delta-5 and delta-6 desaturase activities estimated by serum fatty acid ratios. J Lipid Res (2010) 1.54
Genes encoding endothelin-converting enzyme-1 and endothelin-1 interact to influence blood pressure in women: the EVA study. J Hypertens (2004) 1.49
The impact of the AMPD1 gene polymorphism on exercise capacity, other prognostic parameters, and survival in patients with stable congestive heart failure: a study in 686 consecutive patients. Am Heart J (2006) 1.48
Association between the metabolic syndrome and parental history of premature cardiovascular disease. Eur Heart J (2006) 1.47
Fruits, vegetables and coronary heart disease. Nat Rev Cardiol (2009) 1.47
Body mass index, hypertension and 5-year coronary heart disease incidence in middle aged men: the PRIME study. J Hypertens (2003) 1.45
Genetics of venous thrombosis: insights from a new genome wide association study. PLoS One (2011) 1.43
Lipoprotein (a) as a predictor of coronary heart disease: the PRIME Study. Atherosclerosis (2002) 1.41
The pursuit of susceptibility genes for Alzheimer's disease: progress and prospects. Trends Genet (2010) 1.41
Association between the T-381C polymorphism of the brain natriuretic peptide gene and risk of type 2 diabetes in human populations. Hum Mol Genet (2007) 1.40
Excessive daytime sleepiness is an independent risk indicator for cardiovascular mortality in community-dwelling elderly: the three city study. Stroke (2009) 1.38
Ischemic stroke is associated with the ABO locus: the EuroCLOT study. Ann Neurol (2013) 1.30
Evidence of a role for lactadherin in Alzheimer's disease. Am J Pathol (2007) 1.28
Genetics of Alzheimer's disease: new evidences for an old hypothesis? Curr Opin Genet Dev (2011) 1.25
Association between Parkinson's disease and polymorphisms in the nNOS and iNOS genes in a community-based case-control study. Hum Mol Genet (2003) 1.23
Plasma cystatin-C and development of coronary heart disease: The PRIME Study. Atherosclerosis (2005) 1.19
The CALHM1 P86L polymorphism is a genetic modifier of age at onset in Alzheimer's disease: a meta-analysis study. J Alzheimers Dis (2010) 1.19
Impact of genetic variation of PPARgamma in humans. Mol Genet Metab (2004) 1.17
The role of clusterin, complement receptor 1, and phosphatidylinositol binding clathrin assembly protein in Alzheimer disease risk and cerebrospinal fluid biomarker levels. Arch Gen Psychiatry (2011) 1.16
High consumptions of grain, fish, dairy products and combinations of these are associated with a low prevalence of metabolic syndrome. J Epidemiol Community Health (2007) 1.16
A functional polymorphism in a STAT5B site of the human PPAR gamma 3 gene promoter affects height and lipid metabolism in a French population. Arterioscler Thromb Vasc Biol (2003) 1.12
Two-dimensional maps and databases of the human macrophage proteome and secretome. Proteomics (2004) 1.11
Genome-wide association analysis identifies a susceptibility locus for pulmonary arterial hypertension. Nat Genet (2013) 1.11
Alcohol intake and diet in France, the prominent role of lifestyle. Eur Heart J (2004) 1.11
High blood pressure prevalence and control in a middle-aged French population and their associated factors: the MONA LISA study. J Hypertens (2011) 1.10
Gender differences in the implementation of cardiovascular prevention measures after an acute coronary event. Heart (2010) 1.10
Value of HDL cholesterol, apolipoprotein A-I, lipoprotein A-I, and lipoprotein A-I/A-II in prediction of coronary heart disease: the PRIME Study. Prospective Epidemiological Study of Myocardial Infarction. Arterioscler Thromb Vasc Biol (2002) 1.09
Both common variations and rare non-synonymous substitutions and small insertion/deletions in CLU are associated with increased Alzheimer risk. Mol Neurodegener (2012) 1.08
Bilirubin and coronary heart disease risk in the Prospective Epidemiological Study of Myocardial Infarction (PRIME). Eur J Cardiovasc Prev Rehabil (2007) 1.07
Genome-wide pathway analysis implicates intracellular transmembrane protein transport in Alzheimer disease. J Hum Genet (2010) 1.07
Frequency of fruit and vegetable consumption and coronary heart disease in France and Northern Ireland: the PRIME study. Br J Nutr (2004) 1.07
Usefulness of circulating biomarkers for the prediction of left ventricular remodeling after myocardial infarction. Am J Cardiol (2012) 1.06
Effect of an FTO polymorphism on fat mass, obesity, and type 2 diabetes mellitus in the French MONICA Study. Metabolism (2009) 1.05
Sex hormone-binding globulin is a major determinant of the lipid profile: the PRIME study. Atherosclerosis (2004) 1.04
Association between beta-1 and beta-2 adrenergic receptor gene polymorphisms and the response to beta-blockade in patients with stable congestive heart failure. Pharmacogenet Genomics (2005) 1.04
Distension of the carotid artery and risk of coronary events: the three-city study. Arterioscler Thromb Vasc Biol (2008) 1.04
Systematic analysis of candidate genes for Alzheimer's disease in a French, genome-wide association study. J Alzheimers Dis (2010) 1.03
Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI. Circ Cardiovasc Genet (2015) 1.03
Impact of APOA5/A4/C3 genetic polymorphisms on lipid variables and cardiovascular disease risk in French men. Int J Cardiol (2006) 1.03
Association study of the GAB2 gene with the risk of developing Alzheimer's disease. Neurobiol Dis (2008) 1.03
The proteome and secretome of human arterial smooth muscle cells. Proteomics (2005) 1.02
Association study of the PIN1 gene with Alzheimer's disease. Neurosci Lett (2006) 1.01
Measures of abdominal adiposity and the risk of stroke: the MOnica Risk, Genetics, Archiving and Monograph (MORGAM) study. Stroke (2011) 1.00
C-reactive protein, interleukin 6, fibrinogen and risk of sudden death in European middle-aged men: the PRIME study. Arterioscler Thromb Vasc Biol (2010) 1.00
Evidence of the association of BIN1 and PICALM with the AD risk in contrasting European populations. Neurobiol Aging (2011) 1.00
KNG1 Ile581Thr and susceptibility to venous thrombosis. Blood (2011) 0.98
Residential environment and blood pressure in the PRIME Study: is the association mediated by body mass index and waist circumference? J Hypertens (2008) 0.98
S18Y polymorphism in the UCH-L1 gene and Parkinson's disease: evidence for an age-dependent relationship. Mov Disord (2003) 0.96
Single-nucleotide polymorphism of CD36 locus and obesity in European adolescents. Obesity (Silver Spring) (2009) 0.95
Genome-wide study links MTMR7 gene to variant Creutzfeldt-Jakob risk. Neurobiol Aging (2011) 0.95
Alcohol consumption and cardiovascular disease: differential effects in France and Northern Ireland. The PRIME study. Eur J Cardiovasc Prev Rehabil (2004) 0.94
Association of arginase 1 gene polymorphisms with the risk of myocardial infarction and common carotid intima media thickness. J Med Genet (2007) 0.94
Equivalence of indapamide SR and enalapril on microalbuminuria reduction in hypertensive patients with type 2 diabetes: the NESTOR Study. J Hypertens (2004) 0.94
Impact of APOE gene polymorphisms on the lipid profile in an Algerian population. Lipids Health Dis (2013) 0.94
Excessive daytime sleepiness and vascular events: the Three City Study. Ann Neurol (2012) 0.94
The impact of beta-adrenoreceptor gene polymorphisms on survival in patients with congestive heart failure. Eur J Heart Fail (2005) 0.93
FADS1 genetic variability interacts with dietary α-linolenic acid intake to affect serum non-HDL-cholesterol concentrations in European adolescents. J Nutr (2011) 0.93
Association of vascular risk factors with cervical artery dissection and ischemic stroke in young adults. Circulation (2011) 0.92
Genetic and molecular insights into the role of PROX1 in glucose metabolism. Diabetes (2012) 0.92
Association between peroxisome proliferator-activated receptor gamma haplotypes and the metabolic syndrome in French men and women. Diabetes (2005) 0.92
The Gly16-->Arg16 and Gln27-->Glu27 polymorphisms of beta2-adrenergic receptor are associated with metabolic syndrome in men. J Clin Endocrinol Metab (2003) 0.91
Calf circumference is inversely associated with carotid plaques. Stroke (2008) 0.91
Proteomic analysis of left ventricular remodeling in an experimental model of heart failure. J Proteome Res (2008) 0.91
A possible role for the PPARG Pro12Ala polymorphism in preterm birth. Diabetes (2007) 0.91
Role of proinflammatory CD68(+) mannose receptor(-) macrophages in peroxiredoxin-1 expression and in abdominal aortic aneurysms in humans. Arterioscler Thromb Vasc Biol (2012) 0.91
Multiple biomarkers for the prediction of ischemic stroke: the PRIME study. Arterioscler Thromb Vasc Biol (2013) 0.90
Associations of complement factor H and smoking with early age-related macular degeneration: the ALIENOR study. Invest Ophthalmol Vis Sci (2011) 0.90